公开(公告)号：US20150018930A1

公开(公告)日：2015-01-15

申请号：US14503522

申请日：2014-10-01

Applicant: Medtronic, Inc.

Inventor： Joshua Dwork ,  Hubert Yeung ,  Adam Shipley

IPC: A61F2/966

CPC classification number: A61F2/966 ,  A61F2/95 ,  A61F2002/9505

Abstract: An attachment mechanism for coupling a stent to a delivery system is disclosed. The attachment mechanism is configured to pivot relative to an inner shaft assembly of the delivery system in order to release the stent from the delivery system.

Abstract translation: 公开了一种用于将支架耦合到输送系统的附接机构。 附接机构构造成相对于输送系统的内轴组件枢转，以将支架从输送系统释放。

公开(公告)号：US11612482B2

公开(公告)日：2023-03-28

申请号：US16807010

申请日：2020-03-02

Applicant: Medtronic, Inc.

Inventor： James Keogh ,  Joshua Dwork

IPC: A61F2/24

Abstract: A delivery system for delivering a heart valve prosthesis includes a heart valve prosthesis and a delivery catheter. The heart valve prosthesis includes an anchoring member and an inner valve support, and further includes a radially collapsed configuration and a radially expanded configuration. The delivery catheter includes a handle, an outer shaft, an intermediate shaft, an inner shaft, and a distal tip component. The delivery catheter further includes a delivery configuration. In the delivery configuration, the outer shaft of the delivery catheter is configured to retain a first portion of the anchoring member, the intermediate shaft is configured to retain a first portion of the inner valve support, and the distal tip component is configured to retain a second end of the anchoring member and a second end of the inner valve support each in a radially compressed state.

公开(公告)号：US10321992B2

公开(公告)日：2019-06-18

申请号：US15012533

申请日：2016-02-01

Applicant: Medtronic, Inc.

Inventor： Jason Quill ,  Padraig Savage ,  Joshua Dwork ,  Kshitija Garde ,  Sarah Ahlberg ,  Igor Kovalsky

IPC: A61F2/24

Abstract: Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom. The plurality of support arms may include a main support arm configured to extend from the valve support for capturing at least a portion of a valve leaflet of a native heart valve therebetween when the valve prosthesis is in an expanded configuration and deployed within the native heart valve. In addition, the plurality of support arms may include multiple supplemental support arms disposed about the circumference of the valve support that when deployed in the expanded configuration are configured to at least partially engage subannular tissue at the native heart valve.

公开(公告)号：US20180098846A1

公开(公告)日：2018-04-12

申请号：US15838717

申请日：2017-12-12

Applicant: Medtronic, Inc.

Inventor： Joshua Dwork

IPC: A61F2/24

CPC classification number: A61F2/2427 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2230/0013 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/0039 ,  Y10T29/49405

Abstract: A heart valve prosthesis and delivery systems are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame includes a portion having a crimp that provides additional flexibility to the self-expanding frame in the collapsed configuration.

公开(公告)号：US09492275B2

公开(公告)日：2016-11-15

申请号：US13905632

申请日：2013-05-30

Applicant: Medtronic, Inc.

Inventor： Joshua Dwork

IPC: A61F2/24 ,  A61F2/966

CPC classification number: A61F2/2436 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2002/9665

Abstract: A device for percutaneously delivering a stented prosthetic heart valve. The device includes an inner shaft assembly, a delivery sheath assembly, an outer stability tube, and a handle. The sheath assembly is slidably disposed over the inner shaft, and includes a capsule and a shaft. The capsule compressively contains the prosthesis over the inner shaft. The stability tube is slidably disposed over the delivery sheath, and includes a distal region configured to be radially expandable from a first shape having a first diameter to a second shape having a larger, second diameter. In a first delivery state, the distal region assumes the first shape, providing a low profile appropriate for traversing a patient's vasculature. In a second delivery state, the distal region has the expanded diameter second shape, sized to receive the capsule, such as when retracting the capsule to implant the prosthesis.

公开(公告)号：US09226823B2

公开(公告)日：2016-01-05

申请号：US13658044

申请日：2012-10-23

Applicant: Medtronic, Inc.

Inventor： Joshua Dwork

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2230/0013 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/0039 ,  Y10T29/49405

Abstract: A heart valve prosthesis and delivery systems are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame includes a portion having a crimp that provides additional flexibility to the self-expanding frame in the collapsed configuration.

Abstract translation: 提供心脏瓣膜假体和输送系统以更换心脏瓣膜。 心脏瓣膜假体包括自扩张框架，其包括具有卷曲的部分，其在折叠构型中为自扩张框架提供额外的灵活性。

公开(公告)号：US08974524B2

公开(公告)日：2015-03-10

申请号：US14056467

申请日：2013-10-17

Applicant: Medtronic, Inc.

Inventor： Hubert Yeung ,  John Shanahan ,  Joshua Dwork ,  Adam Shipley ,  Jeffrey Allen ,  Susheel Deshmukh ,  Kishore Udipi ,  Ya Guo

IPC: A61F2/24 ,  A61F2/966 ,  A61F2/95

CPC classification number: A61F2/2436 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/966 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2220/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008

Abstract: A percutaneous stented valve delivery device including an inner shaft, a sheath, and a delivery capsule. The sheath slidably receives the inner shaft. A capsule proximal zone is attached to the sheath. A capsule distal zone is configured to transition between normal and flared states. A diameter of the distal zone is greater in the flared state, and the capsule includes a shape memory component that naturally assumes the normal state. The device is operable to perform a reversible partial deployment procedure in which a portion of the prosthesis is exposed distal the capsule and allowed to radially expand. Subsequently, with distal advancement of the capsule, the distal zone transitions to the flared state and imparts a collapsing force onto the prosthesis, causing the prosthesis to radially collapse and become recaptured within the delivery capsule. The capsule can include a laser cut tube encapsulated by a polymer.

Abstract translation: 一种经皮支架置入的瓣膜输送装置，包括内轴，护套和输送胶囊。 护套可滑动地容纳内轴。 胶囊近端区域附接到护套。 胶囊远端区域被配置为在正常和扩张状态之间转变。 远端区域的直径在扩张状态下较大，并且胶囊包括自然地呈现正常状态的形状记忆组件。 该装置可操作以执行可逆部分展开过程，其中假体的一部分暴露在胶囊的远端并允许径向扩张。 随后，随着胶囊的远端前进，远侧区域转变到扩张状态并且将塌陷力施加到假体上，导致假体径向折叠并在输送胶囊内重新捕获。 胶囊可以包括由聚合物包封的激光切割管。

公开(公告)号：US20140222142A1

公开(公告)日：2014-08-07

申请号：US14175100

申请日：2014-02-07

Applicant: Medtronic, Inc.

Inventor： Igor Kovalsky ,  Cathleen Bergin ,  Marian Creaven ,  Joshua Dwork ,  Kshitija Garde ,  Daniel Glozman ,  Ilia Hariton ,  Pham Lo ,  Jason Quill ,  Jeffrey Sandstrom ,  Padraig Savage ,  Michael Schendel ,  Elizabeth Schotzko ,  Yossi Tuval ,  Nadav Yellin

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2457 ,  A61F2210/0004 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008 ,  A61F2250/0036 ,  A61F2250/0071

Abstract: Heart valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular or central portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion.

Abstract translation: 公开了包括具有流入部分，阀保持管状或中心部分和一对支撑臂的框架或支撑结构的心脏瓣膜假体。 流入部分从阀保持管状部分的第一端径向延伸，并且一对支撑臂沿圆周间隔开并且从阀保持管状部分的相对的第二端径向延伸。

公开(公告)号：US20140046435A1

公开(公告)日：2014-02-13

申请号：US14056467

申请日：2013-10-17

Applicant: Medtronic, Inc.

Inventor： Hubert Yeung ,  John Shanahan ,  Joshua Dwork ,  Adam Shipley ,  Jeffrey Allen ,  Susheel Deshmukh ,  Kishore Udipi ,  Ya Guo

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/966 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2220/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008

Abstract: A percutaneous stented valve delivery device including an inner shaft, a sheath, and a delivery capsule. The sheath slidably receives the inner shaft. A capsule proximal zone is attached to the sheath. A capsule distal zone is configured to transition between normal and flared states. A diameter of the distal zone is greater in the flared state, and the capsule includes a shape memory component that naturally assumes the normal state. The device is operable to perform a reversible partial deployment procedure in which a portion of the prosthesis is exposed distal the capsule and allowed to radially expand. Subsequently, with distal advancement of the capsule, the distal zone transitions to the flared state and imparts a collapsing force onto the prosthesis, causing the prosthesis to radially collapse and become recaptured within the delivery capsule. The capsule can include a laser cut tube encapsulated by a polymer.

Abstract translation: 一种经皮支架置入的瓣膜输送装置，包括内轴，护套和输送胶囊。 护套可滑动地容纳内轴。 胶囊近端区域附接到护套。 胶囊远端区域被配置为在正常和扩张状态之间转变。 远端区域的直径在扩张状态下较大，并且胶囊包括自然地呈现正常状态的形状记忆组件。 该装置可操作以执行可逆部分展开过程，其中假体的一部分暴露在胶囊的远端并允许径向扩张。 随后，随着胶囊的远端前进，远侧区域转变到扩张状态并且将塌陷力施加到假体上，导致假体径向折叠并在输送胶囊内重新捕获。 胶囊可以包括由聚合物包封的激光切割管。