Demand-based cardiac function therapy
    21.
    发明授权
    Demand-based cardiac function therapy 有权
    基于需求的心脏功能治疗

    公开(公告)号:US07392084B2

    公开(公告)日:2008-06-24

    申请号:US10669170

    申请日:2003-09-23

    IPC分类号: A61N1/368

    摘要: A method and device for delivering cardiac function therapy on a demand basis. An implantable device for delivering cardiac function therapy is programmed to suspend such therapy at periodic intervals or upon command from an external programmer. Measurements related to hemodynamic performance are then taken using one or more sensing modalities incorporated into the device. Based upon these measurements, the device uses a decision algorithm to determine whether further delivery of the cardiac function therapy is warranted.

    摘要翻译: 一种用于在需求的基础上提供心脏功能治疗的方法和装置。 用于递送心脏功能治疗的可植入装置被编程为以周期性间隔或根据来自外部编程器的命令来暂停这种治疗。 然后使用结合到该装置中的一种或多种感测模式进行与血液动力学性能相关的测量。 基于这些测量,该设备使用决策算法来确定是否需要进一步递送心脏功能治疗。

    Ablation catheter, system, and method of use thereof
    24.
    发明授权
    Ablation catheter, system, and method of use thereof 失效
    消融导管,系统及其使用方法

    公开(公告)号:US06893438B2

    公开(公告)日:2005-05-17

    申请号:US10286548

    申请日:2002-11-01

    摘要: A cardiac ablation apparatus for producing a circumferential ablation that electrically isolates a heart chamber wall portion from vessel such as a pulmonary vein extending into said wall portion comprises (a) an elongate centering catheter having a distal end portion; (b) an expandable centering element connected to said centering catheter distal end portion and configured for positioning within said vessel when in a retracted configuration, and for securing said elongate centering catheter in a substantially axially aligned position with respect to said vessel when said centering element is in an expanded configuration; (c) an ablation catheter slidably connected to said centering catheter said ablation element having a distal end portion, and (d) an expandable ablation element connected to said ablation catheter distal end portion. The ablation element is configured to form a circumferential ablation on the wall around the elongate centering catheter when the centering catheter is axially aligned with respect to the vessel. In a further embodiment, a non-expandable, compliant centering element is employed, such as an elastic finger. Systems incorporating such an apparatus and methods of use thereof are also disclosed.

    摘要翻译: 一种心脏消融装置,用于产生将心脏室壁部分与血管延伸到所述壁部分中的肺静脉电隔离的周缘消融,包括:(a)具有远端部分的细长定心导管; (b)连接到所述定心导管远端部分并且构造成当处于缩回构型时定位在所述容器内的可扩张定心元件,并且用于当所述定心元件相对于所述容器基本轴向对准的位置时将所述细长定心导管固定 处于扩展配置; (c)消融导管,其可滑动地连接到所述定心导管,所述消融元件具有远端部分,以及(d)可扩张的消融元件,其连接到所述消融导管远端部分。 消融元件构造成当定心导管相对于血管轴向对准时,在围绕细长定心导管的壁上形成周边消融。 在另一个实施例中,使用不可膨胀的柔性定心元件,例如弹性指状物。 还公开了包含这种装置及其使用方法的系统。

    Method and apparatus for treating cardiac arrhythmia using electrogram features
    25.
    发明授权
    Method and apparatus for treating cardiac arrhythmia using electrogram features 有权
    使用电描记图特征治疗心律失常的方法和装置

    公开(公告)号:US06839591B2

    公开(公告)日:2005-01-04

    申请号:US10396946

    申请日:2003-03-24

    IPC分类号: A61N1/39

    CPC分类号: A61N1/3962

    摘要: A method and system for ventricular defibrillation by coordinating the delivery of defibrillation shocks with sensed ventricular fibrillation complexes in a way which improves the probability of success of the defibrillation shock. Ventricular electrical activity is monitored in two ventricular locations during ventricular fibrillation to detect coarse ventricular fibrillation complexes and contractions of the ventricular cardiac tissue. The defibrillation shock is delivered in coordination with the occurrence of coarse ventricular fibrillation complexes and the contractions of ventricular cardiac tissue, and specifically to occur on the up-slope portion thereof, for optimal probability of success.

    Cardiac rhythm management system with arrhythmia prediction and prevention
    26.
    发明授权
    Cardiac rhythm management system with arrhythmia prediction and prevention 有权
    心律失常预防与心律失常管理系统

    公开(公告)号:US06400982B2

    公开(公告)日:2002-06-04

    申请号:US09850283

    申请日:2001-05-07

    IPC分类号: A61B50452

    摘要: A cardiac rhythm management system predicts when an arrhythmia will occur and in one embodiment invokes a therapy to prevent or reduce the consequences of the arrhythmia. A cardiac arrhythmia trigger/marker is detected from a patient, and based on the trigger/marker, the system estimates a probability of a cardiac arrhythmia occurring during a predetermined future time interval. The system provides a list of triggers/markers, for which detection values are recurrently obtained at various predetermined time intervals. Based on detection values and conditional probabilities associated with the triggers/markers, a probability estimate of a future arrhythmia is computed. An arrhythmia prevention therapy is selected and activated based on the probability estimate of the future arrhythmia.

    摘要翻译: 心律管理系统预测何时发生心律失常,并且在一个实施例中调用治疗以预防或减少心律失常的后果。 从患者检测到心律失常触发/标记,并且基于触发/标记,系统估计在预定的未来时间间隔期间发生心律失常的概率。 该系统提供了一个触发/标记列表,为各种预定时间间隔循环获得检测值。 基于与触发/标记相关联的检测值和条件概率,计算未来心律失常的概率估计。 基于对未来心律失常的概率估计,选择并激活心律失常预防疗法。

    Method and apparatus for treating cardiac arrhythmia using electrogram
features

    公开(公告)号:US6112117A

    公开(公告)日:2000-08-29

    申请号:US852103

    申请日:1997-05-06

    IPC分类号: A61N1/39

    CPC分类号: A61N1/3962

    摘要: A method and system for ventricular defibrillation by coordinating the delivery of defibrillation shocks with sensed ventricular fibrillation complexes in a way which improves the probability of success of the defibrillation shock. Ventricular electrical activity is monitored in two ventricular locations during ventricular fibrillation to detect coarse ventricular fibrillation complexes and contractions of the ventricular cardiac tissue. The defibrillation shock is delivered in coordination with the occurrence of coarse ventricular fibrillation complexes and the contractions of ventricular cardiac tissue, and specifically to occur on the up-slope portion thereof, for optimal probability of success.

    Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction

    公开(公告)号:US10188856B1

    公开(公告)日:2019-01-29

    申请号:US13314119

    申请日:2011-12-07

    IPC分类号: A61N1/18 A61N1/05 A61N1/36

    摘要: An implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction is provided. A stimulation therapy lead includes helical electrodes configured to conform to an outer diameter of a cervical vagus nerve sheath, and a set of connector pins electrically connected to the helical electrodes. A neurostimulator includes an electrical receptacle into which the connector pins are securely and electrically coupled. The neurostimulator also includes a pulse generator configured to therapeutically stimulate the vagus nerve through the helical electrodes in alternating cycles of stimuli application and stimuli inhibition that are tuned to both efferently activate the heart's intrinsic nervous system and afferently activate the patient's central reflexes by triggering bi-directional action potentials.

    Implantable device for evaluating autonomic cardiovascular drive in a patient suffering from chronic cardiac dysfunction
    29.
    发明授权
    Implantable device for evaluating autonomic cardiovascular drive in a patient suffering from chronic cardiac dysfunction 有权
    用于评估患有慢性心脏功能障碍的患者的自主心血管驱动的植入式装置

    公开(公告)号:US08918190B2

    公开(公告)日:2014-12-23

    申请号:US13314133

    申请日:2011-12-07

    IPC分类号: A61N1/32

    摘要: An implantable device for evaluating autonomic cardiovascular drive in a patient suffering from chronic cardiac dysfunction is provided. A stimulation therapy lead includes helical electrodes configured to conform to an outer diameter of a cervical vagus nerve sheath, and a set of connector pins electrically connected to the helical electrodes. A neurostimulator includes an electrical receptacle into which the connector pins are securely and electrically coupled. The neurostimulator also includes a pulse generator configured to therapeutically stimulate the vagus nerve through the helical electrodes in alternating cycles of stimuli application and stimuli inhibition that are tuned to both efferently activate the heart's intrinsic nervous system and afferently activate the patient's central reflexes by triggering bi-directional action potentials. The neurostimulator includes a recordable memory storing a baseline heart rate. The neurostimulator includes an integrated leadless heart rate sensor configured to continually monitor heart rate in light of the baseline heart rate.

    摘要翻译: 提供了一种用于评估患有慢性心脏功能障碍的患者的自主心血管驱动的可植入装置。 刺激治疗引线包括构造成符合颈部迷走神经鞘的外径的螺旋电极和电连接到螺旋电极的一组连接器引脚。 神经刺激器包括一个电插座,连接器插头牢固地和电连接到该插座中。 神经刺激器还包括脉冲发生器,其被配置为在刺激应用和刺激抑制的交替周期中通过螺旋电极治疗性地刺激迷走神经,该循环被调谐到两者以显着激活心脏的内在神经系统,并通过触发双向激活来传入激活患者的中心反射, 方向动作电位。 神经刺激器包括存储基线心率的可记录存储器。 神经刺激器包括集成无引线心率传感器,其配置成根据基线心率不断监测心率。

    Method and apparatus for establishing context among events and optimizing implanted medical device performance
    30.
    发明授权
    Method and apparatus for establishing context among events and optimizing implanted medical device performance 有权
    用于在事件之间建立上下文并优化植入的医疗设备性能的方法和装置

    公开(公告)号:US08694116B2

    公开(公告)日:2014-04-08

    申请号:US13447816

    申请日:2012-04-16

    IPC分类号: A61N1/08

    摘要: An apparatus and method for adjusting the performance of an implanted device based on data including contextual information. Contextual information, including operational and performance data concerning the implanted device as well as the patient with the implanted device, is stored by a portable electronic device. In one embodiment, the portable electronic device is adapted for battery operation and includes a personal digital assistant (PDA). The portable electronic device is adapted for use as an interface to conduct wireless communications with the implanted device. In one embodiment, the portable electronic device interfaces with a clinical programmer for use by a physician.

    摘要翻译: 一种用于基于包括上下文信息的数据来调整植入装置的性能的装置和方法。 上下文信息,包括关于植入装置的操作和性能数据以及具有植入装置的患者,由便携式电子装置存储。 在一个实施例中,便携式电子设备适用于电池操作并且包括个人数字助理(PDA)。 便携式电子设备适于用作与植入的设备进行无线通信的接口。 在一个实施例中,便携式电子设备与临床程序员接口以供医生使用。