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公开(公告)号：US20150141972A1
公开(公告)日：2015-05-21
申请号：US14509850
申请日：2014-10-08
发明人： Bruce Woodley , Javier Gonzalez
CPC分类号： A61F9/008 , A61B3/102 , A61F9/00804 , A61F9/00827 , A61F9/0084 , A61F2009/00851 , A61F2009/00855 , A61F2009/00882 , G01B9/02091
摘要： A laser system is calibrated with a tomography system capable of measuring locations of structure within an optically transmissive material such as a tissue of an eye. Alternatively or in combination, the tomography system can be used to track the location of the eye and adjust the treatment in response to one or more of the location or an orientation of the eye. In many embodiments, in situ calibration and tracking of an optically transmissive tissue structure such as an eye can be provided. The optically transmissive material may comprise one or more optically transmissive structures of the eye, or a non-ocular optically transmissive material such as a calibration gel in a container or an optically transmissive material of a machined part.
摘要翻译： 使用能够测量透光材料（例如眼睛组织）内的结构位置的断层摄影系统对激光系统进行校准。 替代地或组合地，层析摄影系统可以用于跟踪眼睛的位置并且响应于眼睛的位置或取向中的一个或多个来调整治疗。 在许多实施例中，可以提供诸如眼睛之类的光学透射组织结构的原位校准和跟踪。 光学透射材料可以包括眼睛的一个或多个光学透射结构，或非眼睛透光材料，例如容器中的校准凝胶或加工部件的光学透射材料。
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公开(公告)号：US20140114296A1
公开(公告)日：2014-04-24
申请号：US14062401
申请日：2013-10-24
发明人： Bruce Woodley , Javier Gonzales , Katrina Bell Sheehy , Daniel Oliveira Santos , Darrel Q. Pham , Paul Daniel Gallagher , Lawrence Edward Miller
CPC分类号： A61B5/4836 , A61B3/0008 , A61B3/1005 , A61B3/102 , A61B5/7425 , A61B5/748 , A61B34/25 , A61B2034/107 , A61B2034/258 , A61B2090/3735 , A61F9/00736 , A61F9/00754 , A61F9/008 , A61F9/009
摘要： Methods and systems for planning and forming incisions in a cornea, lens capsule, and/or crystalline lens nucleus are disclosed. A method includes measuring spatial dispositions, relative to a laser surgery system, of at least portions of the corneal anterior and posterior surfaces. A spatial disposition of an incision of the cornea is generated based at least in part on the measured corneal anterior and posterior spatial dispositions and at least one corneal incision parameter. A composite image is displayed that includes an image representative of the measured corneal anterior and posterior surfaces and an image representing the corneal incision.
摘要翻译： 公开了用于在角膜，晶状体囊和/或晶状体核中规划和形成切口的方法和系统。 一种方法包括测量相对于激光手术系统的角膜前表面和后表面的至少部分的空间布置。 至少部分地基于所测量的角膜前后空间布置和至少一个角膜切开参数产生角膜切口的空间布置。 显示包括表示测量的角膜前表面和后表面的图像和表示角膜切口的图像的合成图像。
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公开(公告)号：US20200038244A1
公开(公告)日：2020-02-06
申请号：US16601478
申请日：2019-10-14
发明人： Javier G. Gonzalez , Bruce Woodley
摘要： Systems and methods automatically locate optical surfaces of an eye and automatically generate surface models of the optical surfaces. A method includes OCT scanning of an eye. Returning portions of a sample beam are processed to locate a point on the optical surface and first locations on the optical surface within a first radial distance of the point. A first surface model of the optical surface is generated based on the location of the point and the first locations. Returning portions of the sample beam are processed so as to detect second locations on the optical surface beyond the first radial distance and within a second radial distance from the point. A second surface model of the optical surface is generated based on the location of the point on the optical surface and the first and second locations on the optical surface.
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公开(公告)号：US10441464B2
公开(公告)日：2019-10-15
申请号：US15376491
申请日：2016-12-12
发明人： Javier G. Gonzalez , Bruce Woodley
摘要： Systems and methods automatically locate optical surfaces of an eye and automatically generate surface models of the optical surfaces. A method includes OCT scanning of an eye. Returning portions of a sample beam are processed to locate a point on the optical surface and first locations on the optical surface within a first radial distance of the point. A first surface model of the optical surface is generated based on the location of the point and the first locations. Returning portions of the sample beam are processed so as to detect second locations on the optical surface beyond the first radial distance and within a second radial distance from the point. A second surface model of the optical surface is generated based on the location of the point on the optical surface and the first and second locations on the optical surface.
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公开(公告)号：US20190076017A1
公开(公告)日：2019-03-14
申请号：US16188119
申请日：2018-11-12
发明人： Georg Schuele , Noah Bareket , David Dewey , John S. Hart , Javier G. Gonzalez , Raymond Woo , Thomas Z. Teisseyre , Jeffrey A. Golda , Katrina B. Sheehy , Madeleine C O'Meara , Bruce Woodley
摘要： A laser surgery system includes a light source, an eye interface device, a scanning assembly, a confocal detection assembly and preferably a confocal bypass assembly. The light source generates an electromagnetic beam. The scanning assembly scans a focal point of the electromagnetic beam to different locations within the eye. An optical path propagates the electromagnetic beam from a light source to the focal point, and also propagates a portion of the electromagnetic beam reflected from the focal point location back along at least a portion of the optical path. The optical path includes an optical element associated with a confocal detection assembly that diverts a portion of the reflected electromagnetic radiation to a sensor. The sensor generates an intensity signal indicative of intensity the electromagnetic beam reflected from the focal point location. The confocal bypass assembly reversibly diverts the electromagnetic beam along a diversion optical path around the optical element.
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公开(公告)号：US20180207031A1
公开(公告)日：2018-07-26
申请号：US15924121
申请日：2018-03-16
发明人： Bruce Woodley , Javier Gonzalez
CPC分类号： A61F9/008 , A61B3/102 , A61F9/00804 , A61F9/00827 , A61F9/0084 , A61F2009/00851 , A61F2009/00855 , A61F2009/00882 , G01B9/02091
摘要： A laser system is calibrated with a tomography system capable of measuring locations of structure within an optically transmissive material such as a tissue of an eye. Alternatively or in combination, the tomography system can be used to track the location of the eye and adjust the treatment in response to one or more of the location or an orientation of the eye. In many embodiments, in situ calibration and tracking of an optically transmissive tissue structure such as an eye can be provided. The optically transmissive material may comprise one or more optically transmissive structures of the eye, or a non-ocular optically transmissive material such as a calibration gel in a container or an optically transmissive material of a machined part.
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27.发明申请METHOD AND APPARATUS FOR AUTOMATED PLACEMENT OF SCANNED LASER CAPSULORHEXIS INCISIONS 审中-公开自动放置扫描激光加速器的方法和装置公开(公告)号：US20170027756A1
公开(公告)日：2017-02-02
申请号：US15294436
申请日：2016-10-14
CPC分类号： A61F9/00825 , A61B3/102 , A61B3/107 , A61B5/0066 , A61F9/008 , A61F9/0084 , A61F9/009 , A61F2009/00851 , A61F2009/00865 , A61F2009/0087 , A61F2009/00872 , A61F2009/00876 , A61F2009/00889 , A61F2009/00897 , G06T7/0012 , G06T7/13 , G06T7/149 , G06T2207/10101 , G06T2207/30041
摘要： Systems and methods are described for cataract intervention. In one embodiment a system comprises a laser source configured to produce a treatment beam comprising a plurality of laser pulses; an integrated optical system comprising an imaging assembly operatively coupled to a treatment laser delivery assembly such that they share at least one common optical element, the integrated optical system being configured to acquire image information pertinent to one or more targeted tissue structures and direct the treatment beam in a 3-dimensional pattern to cause breakdown in at least one of the targeted tissue structures; and a controller operatively coupled to the laser source and integrated optical system, and configured to adjust the laser beam and treatment pattern based upon the image information, and distinguish two or more anatomical structures of the eye based at least in part upon a robust least squares fit analysis of the image information.
摘要翻译： 描述白内障干预的系统和方法。 在一个实施例中，系统包括被配置为产生包括多个激光脉冲的治疗束的激光源; 一种集成光学系统，包括可操作地耦合到治疗激光输送组件的成像组件，使得它们共享至少一个公共光学元件，所述集成光学系统被配置为获取与一个或多个目标组织结构相关的图像信息，并且指导治疗束 在3维图案中以引起至少一个目标组织结构中的破坏; 以及控制器，其可操作地耦合到所述激光源和集成光学系统，并且被配置为基于所述图像信息来调整所述激光束和治疗图案，并且至少部分地基于鲁棒的最小二乘法来区分所述眼睛的两个或多个解剖结构 适合分析图像信息。
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公开(公告)号：US20140128853A1
公开(公告)日：2014-05-08
申请号：US14069703
申请日：2013-11-01
发明人： David Angeley , Bruce Woodley , David Dewey , Mike Simoneau , Georg Schuele
IPC分类号： A61F9/008
CPC分类号： A61F9/00827 , A61F9/009 , A61F2009/00846 , A61F2009/0087 , A61F2009/00872 , A61F2009/00887 , A61F2009/00889
摘要： The amount of energy to provide optical breakdown can be determined based on mapped optical breakdown thresholds of the treatment volume, and the laser energy can be adjusted in response to the mapped breakdown thresholds. The mapping of threshold energies can be combined with depth and lateral calibration in order to determine the location of optical breakdown along the laser beam path for an amount of energy determined based on the mapping. The mapping can be used with look up tables to determine mapped locations from one reference system to another reference system.
摘要翻译： 可以基于处理体积的映射光学击穿阈值来确定提供光学击穿的能量的量，并且可以响应于映射的击穿阈值来调整激光能量。 阈值能量的映射可以与深度和横向校准相结合，以便根据映射确定一定量的能量沿着激光束路径确定光学击穿的位置。 映射可以与查找表一起使用，以确定从一个参考系统到另一个参考系统的映射位置。
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