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21.发明申请CATHETER COMPRISING CAPACITIVE MICROMACHINED ULTRASONIC TRANSDUCERS WITH AN ADJUSTABLE FOCUS 有权包含具有可调焦点的电容式微超声波超声波传感器的导管公开(公告)号：US20140005521A1
公开(公告)日：2014-01-02
申请号：US13885791
申请日：2011-11-15
CPC分类号： A61B5/015 , A61B5/055 , A61B5/064 , A61B5/4836 , A61B6/03 , A61B6/12 , A61B6/4057 , A61B8/0841 , A61B8/12 , A61B8/445 , A61B8/4488 , A61B8/54 , A61B8/58 , A61B2018/00023 , A61B2090/064 , A61B2090/374 , A61B2562/028 , A61N7/022 , A61N2007/0095 , B06B1/0292 , G06F19/00
摘要： A catheter (700, 800, 1206) comprising: a shaft with distal (808, 906, 1004, 208) and proximal ends (1006),wherein the distal end comprises at least one array of capacitive micromachined ultrasound transducers (308, 402, 404, 500, 512, 600, 604, 802, 008) with an adjustable focus for controllably heating a target zone (806, 1014, 1210); and a connector (1012) at the proximal end for supplying the at least one array of capacitive micromachined ultrasound transducers with electrical power and for controlling the adjustable focus.
摘要翻译： 导管（700,800,1206）包括：具有远端（808,906,1004,208）和近端（1006）的轴，其中所述远端包括至少一个电容微加工超声换能器阵列（308,402， 具有可调焦点，用于可控制地加热目标区域（806,104,1210）; 以及在所述近端处的用于向所述至少一个电容微加工超声换能器阵列供电并用于控制所述可调焦点的连接器（1012）。
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22.发明申请公开(公告)号：US20100106005A1
公开(公告)日：2010-04-29
申请号：US12531495
申请日：2008-03-07
CPC分类号： A61N7/02 , A61B90/39 , A61B2090/374 , A61B2090/376 , A61N5/1049 , A61N2005/1061
摘要： The present disclosure provides for effective systems and methods for increasing target tissue conspicuity within a particular anatomy of a particular patient. In an exemplary embodiment, a system associated with the present disclosure includes: (a) a MRI-guided HIFU system for generating ablation markings on a target tissue region, the MRI-guided HIFU system including a transducer for delivering HIFU to the target tissue region, the delivered HIFU generating the ablation markings on the target tissue and an MRI imaging system adapted to generate a three dimensional image of the target tissue region during HIFU delivery for guiding the delivery of the HIFU to the target tissue region; (b) a radiotherapy delivery system for delivering radiotherapy treatment to the target tissue region; and (c) a CT imaging system operable within the radiotherapy delivery system for generating a three dimensional image of the target tissue region. The markings generated on the target tissue region by the MRI-guided HIFU are visible in the image generated by the CT imaging system. The image generated by the CT imaging system guides the location of the radiotherapy treatment delivered to the target tissue region.
摘要翻译： 本公开提供了用于增加特定患者的特定解剖结构内的目标组织显着性的有效系统和方法。 在示例性实施例中，与本公开相关联的系统包括：（a）用于在目标组织区域上产生消融标记的MRI引导的HIFU系统，所述MRI引导的HIFU系统包括用于将HIFU传送到目标组织区域的换能器 所传送的HIFU在靶组织上产生消融标记，以及MRI成像系统，其适于在HIFU递送期间产生目标组织区域的三维图像，用于将HIFU传送到目标组织区域; （b）放射治疗递送系统，用于向目标组织区域递送放射治疗; 和（c）可在放射治疗递送系统内操作的用于产生目标组织区域的三维图像的CT成像系统。 通过MRI引导的HIFU在靶组织区域上产生的标记在CT成像系统产生的图像中是可见的。 由CT成像系统产生的图像引导放射治疗治疗传送到目标组织区域的位置。
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公开(公告)号：US20100016765A1
公开(公告)日：2010-01-21
申请号：US12520432
申请日：2007-12-19
摘要： A method and apparatus for the integration of an ultrasound transducer with a SPECT imaging system is disclosed. The ultrasound transducer allows the delivery of particle-born drug therapies or thermally active therapies at the same site detected with SPECT imaging. The system includes a SPECT imaging subsystem; an ultrasound transducer for producing a signal representative of applied ultrasound and signally coupled to the SPECT imaging subsystem; and co-registering means for co-registering the signal representative of applied ultrasound in a coordinate system of SPECT imaging subsystem. The SPECT subsystem may be replaced with a SPECT/CT combined system to provide morphology that allows for treatment planning. In another embodiment, the ultrasound transducer can be used intermittently with the sequential gathering of SPECT images for tracking time-varying properties of the binding of specific SPECT contrast agents to biomarkers of disease. In this way, the ultrasound and SPECT imaging devices form a novel combination to improve patient care through improved spatial registration, therapy planning, and workflow.
摘要翻译： 公开了一种用于将超声换能器与SPECT成像系统集成的方法和装置。 超声换能器允许在用SPECT成像检测的相同部位输送粒子出生的药物治疗或热活性治疗。 该系统包括一个SPECT成像子系统; 超声换能器，用于产生代表施加的超声波并且信号耦合到SPECT成像子系统的信号; 以及用于在SPECT成像子系统的坐标系中共同对应表示应用的超声波的信号的共同配准装置。 可以用SPECT / CT组合系统替换SPECT子系统，以提供允许治疗计划的形态。 在另一个实施例中，可以间歇地使用超声换能器与SPECT图像的顺序收集，以跟踪特定SPECT造影剂与疾病生物标志物的结合的时变特性。 以这种方式，超声和SPECT成像装置形成了一种新颖的组合，通过改进空间注册，治疗计划和工作流程来改善患者的护理。
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公开(公告)号：US20080208059A1
公开(公告)日：2008-08-28
申请号：US11908199
申请日：2006-03-02
IPC分类号： A61B8/00
CPC分类号： A61B8/481 , A61B8/4281
摘要： Method and system for ultrasound imaging of body tissue in which a focused ultrasound (FUS) transducer (20) is oriented relative to the body such that ultrasonic waves generated by the FUS transducer (20) are directed toward the tissue being imaged. The FUS transducer (20) is operated to cause the formation of microbubbles (28) in the tissue and an ultrasound image of the tissue with the microbubbles (28) is acquired. Phase aberration in the acquired ultrasound image may be corrected, if necessary, using each microbubble (28) as a point source or point-like scatterer. Microbubble (28) formation can therefore be obtained in a non-invasive manner since FUS-induced microbubble (28) formation does not require the insertion of interventional tools into the body.
摘要翻译： 其中聚焦超声（FUS）换能器（20）相对于身体定向的身体组织的超声成像的方法和系统，使得由FUS换能器（20）产生的超声波指向被成像的组织。 操作FUS换能器（20）以在组织中形成微泡（28），并且获取具有微泡（28）的组织的超声图像。 如果需要，可以使用每个微泡（28）作为点源或点状散射体来校正所获取的超声图像中的相位差。 因此，由于FUS诱导的微泡（28）形成不需要将介入工具插入体内，因此可以非侵入性方式获得微泡（28）形成。
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