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公开(公告)号:US20100311735A1
公开(公告)日:2010-12-09
申请号:US12742997
申请日:2008-09-11
申请人: Youla S. Tsantrizos , Murray D. Bailey , Francois Bilodeau , Rene Coulombe , Teddy Halmos , Stephen Kawai , Serge R. Landry , Steven LaPlante , Sebastien Morin , Marc-Andre Poupart , Bruno Simoneau , Lee Fader , Rebekah J. Carson , Mathieu Parisien
发明人: Youla S. Tsantrizos , Murray D. Bailey , Francois Bilodeau , Rene Coulombe , Teddy Halmos , Stephen Kawai , Serge R. Landry , Steven LaPlante , Sebastien Morin , Marc-Andre Poupart , Bruno Simoneau , Lee Fader , Rebekah J. Carson , Mathieu Parisien
IPC分类号: A61K31/5383 , C07D215/14 , A61K31/47 , C07D405/10 , A61K31/4709 , C07D401/10 , C07D491/16 , A61K31/4741 , C07D413/10 , A61K31/538 , C07D498/06 , A61P31/18
CPC分类号: C07D215/14 , A61K31/47 , A61K31/4709 , A61K31/473 , A61K31/4741 , A61K31/538 , A61K31/5383 , C07D215/18 , C07D221/16 , C07D401/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D491/06 , C07D498/06
摘要: Compounds of formula I: wherein R4, R6 and R7 are defined herein, are useful as inhibitors of HIV replication.
摘要翻译: 式I化合物(其中R 4,R 6和R 7在本文中定义)可用作HIV复制的抑制剂。
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公开(公告)号:US20080109946A1
公开(公告)日:2008-05-15
申请号:US11586678
申请日:2006-10-26
申请人: Bastien Jourde , Martin Laberge , Sebastien Morin
发明人: Bastien Jourde , Martin Laberge , Sebastien Morin
IPC分类号: A42B1/06
摘要: A sports helmet having a front shell adapted to cover a front portion of a head of a wearer, a rear shell adapted to cover a rear portion of the head of the wearer, the rear shell cooperating with the front shell to surround the head, and a plurality of straps interconnecting the front and rear shells, the straps being connected to the front shell along an inner surface thereof.
摘要翻译: 一种运动头盔,其具有适于覆盖佩戴者头部前部的前壳,适于覆盖佩戴者头部后部的后壳,后壳与前壳协调以围绕头部,以及 连接前壳和后壳的多个带子,带子沿其内表面连接到前壳体。
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公开(公告)号:US08349839B2
公开(公告)日:2013-01-08
申请号:US12756276
申请日:2010-04-08
申请人: Claudio Sturino , Patrick Deroy , Martin Duplessis , Paul J. Edwards , Anne-Marie Faucher , Teddy Halmos , Clint James , Jean-Eric Lacoste , Eric Malenfant , Joannie Minville , Louis Morency , Sebastien Morin , Martin Tremblay , Christiane Yoakim
发明人: Claudio Sturino , Patrick Deroy , Martin Duplessis , Paul J. Edwards , Anne-Marie Faucher , Teddy Halmos , Clint James , Jean-Eric Lacoste , Eric Malenfant , Joannie Minville , Louis Morency , Sebastien Morin , Martin Tremblay , Christiane Yoakim
IPC分类号: A61K31/501 , A61K31/34 , C07D237/36 , C07D307/92
CPC分类号: C07D491/048 , C07D487/04 , C07D491/147 , C07D513/04 , C07D519/00
摘要: Compounds of formula (I): wherein R1, R2, A1, A2, A3, A4, X and Y are as defined herein, are useful as inhibitors of HIV replication.
摘要翻译: 式(I)化合物:其中R1,R2,A1,A2,A3,A4,X和Y如本文所定义,可用作HIV复制的抑制剂。
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公开(公告)号:USD637766S1
公开(公告)日:2011-05-10
申请号:US29352367
申请日:2009-12-18
申请人: Sebastien Morin
设计人: Sebastien Morin
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公开(公告)号:US20100305115A1
公开(公告)日:2010-12-02
申请号:US12743143
申请日:2008-11-03
申请人: Rebekah J. Carson , Lee Fader , Stephen Kawai , Serge R. Landry , Youla S. Tsantrizos , Christian Brochu , Sebastien Morin , Mathieu Parisien , Bruno Simoneau
发明人: Rebekah J. Carson , Lee Fader , Stephen Kawai , Serge R. Landry , Youla S. Tsantrizos , Christian Brochu , Sebastien Morin , Mathieu Parisien , Bruno Simoneau
IPC分类号: A61K31/538 , C07D495/04 , A61K31/4365 , C07D491/06 , A61K31/436 , A61P31/18
CPC分类号: C07D495/04 , C07D519/00
摘要: The present invention relates to compounds of formula (I) wherein c, X, Y, R2, R3, R4 and R6 are as defined herein, compositions and uses thereof for treating human immunodeficiency virus (HIV) infection. In particular, the present invention provides novel inhibitors of HIV integrase, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HIV infection
摘要翻译: 本发明涉及其中c,X,Y,R 2,R 3,R 4和R 6如本文所定义的式(I)化合物,其用于治疗人类免疫缺陷病毒(HIV)感染的组合物和用途。 特别地,本发明提供HIV整合酶的新型抑制剂,含有这些化合物的药物组合物和使用这些化合物治疗HIV感染的方法
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公开(公告)号:US20070079429A1
公开(公告)日:2007-04-12
申请号:US11529358
申请日:2006-09-29
IPC分类号: A42B1/06
CPC分类号: A42B3/324
摘要: A helmet having a helmet shell including cooperating first and second sections in slidable engagement with one another, at least one locking assembly inter-connecting the first and second sections, the locking assembly including a pivoting member pivotable between a locked position and an unlocked position, the pivoting member in the locked position pressing the shell sections against one another such as to prevent a relative sliding motion therebetween, the pivoting member in the unlocked position allowing the relative sliding motion, and at least one engagement member connected to the first shell section and removably engaging the pivoting member in the locked position to prevent accidental movement of the pivoting member toward the unlocked position.
摘要翻译: 一种具有头盔外壳的头盔,包括协作的第一和第二部分,彼此可滑动地接合;至少一个锁定组件,其相互连接所述第一和第二部分,所述锁定组件包括枢转构件,所述枢转构件可在锁定位置和解锁位置之间枢转, 所述枢转构件处于所述锁定位置,以将所述壳部分彼此抵靠,以防止其间的相对滑动,所述枢转构件处于所述解锁位置,允许所述相对滑动运动,以及至少一个接合构件连接到所述第一壳部分,以及 可枢转地将枢转构件接合在锁定位置,以防止枢转构件朝向解锁位置的意外移动。
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公开(公告)号:US09226539B2
公开(公告)日:2016-01-05
申请号:US12835101
申请日:2010-07-13
CPC分类号: A42B3/324
摘要: A helmet has a rigid shell and an adjustable liner connected to the shell. The liner has a plurality of pads located in the shell cavity. The pads are movable with respect to the interior shell surface between a first position near the interior shell surface and a second position further away. In some embodiments, pads are biased towards their second position and the act of the wearer inserting his head into the helmet causes the pads to move towards their first position while remaining biased against the head of the wearer to assist in causing the liner to conform to the head of the wearer. In other embodiments, constriction of the pads moves pads from their second position to their first position, for this same purpose. In other embodiments, pads having both of the aforementioned characteristics are present.
摘要翻译: 头盔具有刚性外壳和连接到外壳的可调节衬垫。 衬套具有位于壳腔中的多个衬垫。 垫可相对于内壳表面在靠近内壳表面的第一位置和远离第二位置之间移动。 在一些实施例中,垫朝向其第二位置偏置,并且佩戴者将其头部插入头盔的动作使得垫朝向其第一位置移动,同时保持偏压抵靠穿着者的头部,以帮助使衬垫符合 佩戴者的头部。 在其它实施例中,为了相同的目的,垫的收缩将垫从它们的第二位置移动到它们的第一位置。 在其他实施例中,存在具有上述特征的焊盘。
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公开(公告)号:US08198458B2
公开(公告)日:2012-06-12
申请号:US12364551
申请日:2009-02-03
申请人: Patrick DeRoy , Anne-Marie Faucher , Alexandre Gagnon , Serge R. Landry , Sebastien Morin , Jeffrey O'Meara , Bruno Simoneau , Bounkham Thavonekham , Christiane Yoakim
发明人: Patrick DeRoy , Anne-Marie Faucher , Alexandre Gagnon , Serge R. Landry , Sebastien Morin , Jeffrey O'Meara , Bruno Simoneau , Bounkham Thavonekham , Christiane Yoakim
IPC分类号: A61K31/41 , C07D257/04
CPC分类号: C07D257/04 , A61K31/41 , A61K31/4439 , A61K31/454 , A61K31/4709 , A61K31/495 , A61K31/5377 , A61K31/541 , C07D231/18 , C07D233/84 , C07D249/08 , C07D249/12 , C07D277/36 , C07D285/06 , C07D285/125 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12
摘要: Compounds of formula (I): wherein Ar, X, R1, R2, R3 and R4 are as defined herein. The compounds are useful as reverse transcriptase inhibitors against wild type and single or double mutant strains of HIV.
摘要翻译: 式(I)化合物:其中Ar,X,R 1,R 2,R 3和R 4如本文所定义。 该化合物可用作针对野生型和单突变或双突变株的逆转录酶抑制剂。
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公开(公告)号:USD637767S1
公开(公告)日:2011-05-10
申请号:US29352368
申请日:2009-12-18
申请人: Sebastien Morin
设计人: Sebastien Morin
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公开(公告)号:USD534483S1
公开(公告)日:2007-01-02
申请号:US29245217
申请日:2005-12-20
申请人: Maurice Graas , Sebastien Morin
设计人: Maurice Graas , Sebastien Morin
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