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35 条记录 (耗时 0.025 秒)

    System and method for serum based cancer detection
    22.
    发明授权
    System and method for serum based cancer detection 有权

    公开(公告)号：US11145411B2

    公开(公告)日：2021-10-12

    申请号：US14440987

    申请日：2013-11-06

    申请人： CHEMIMAGE CORPORATION ,  Patrick Treado ,  Shona Stewart ,  Heather Kirschner ,  Ryan Priore ,  Alan Wilson

    发明人： Patrick Treado ,  Shona Stewart ,  Heather Kirschner ,  Ryan Priore ,  Alan Wilson

    IPC分类号： G01N21/65 ,  G01N33/49 ,  G16H50/20 ,  G16B40/00 ,  G01N33/574 ,  G01J3/44 ,  G01J3/18

    摘要： A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.

    Overpressure indicating reverse buckling disk apparatus
    24.
    发明授权
    Overpressure indicating reverse buckling disk apparatus 有权
    超压指示反屈曲盘装置

    公开(公告)号：US08387647B1

    公开(公告)日：2013-03-05

    申请号：US13110585

    申请日：2011-05-18

    申请人： Alan Wilson

    发明人： Alan Wilson

    IPC分类号： F16K17/40

    CPC分类号： F16K17/1606 ,  F16K37/0008 ,  Y10T137/1707 ,  Y10T137/1737 ,  Y10T137/1744

    摘要： An overpressure indicating disk apparatus for indicating an over pressure condition in a pressurized system includes a body having first and second end portions and a bore, the first end portion configured for attachment to the pressurized system and in pressure communication therewith so that the pressure in the bore is the same pressure as the pressure of the pressurized system. A reverse buckling disk having an annular peripheral portion and a concave convex dome portion is provided. The annular peripheral portion surrounds the dome. The disk annular peripheral portion is mounted to the body, closing the bore at the first end portion. An indicating component or ring is affixed to the combination of a body and reverse buckling disk. The indicating ring has an annular peripheral portion that aligns generally with the annular peripheral portion of the reverse buckling rupture disk. A movable central tab portion is mounted inside the indicating component or ring. A hinge connects the central tab portion to the indicating ring. The concave side of the reverse buckling disk faces the central tab. The convex side of the reverse buckling disk faces the pressure inside the bore. When the pressure in the bore exceeds a preselected maximum pressure value, the disk reverses to engage and displace the central tab thereby indicating visually that an overpressure condition exists within the bore.

    摘要翻译： 用于指示加压系统中的过压状态的超压指示盘装置包括具有第一和第二端部和孔的主体，第一端部构造成用于附接到加压系统并与其进行压力连通， 孔与压力系统的压力相同。 提供具有环形周边部分和凹形凸起圆顶部分的反向弯曲盘。 环形周边部分围绕圆顶。 盘状环形周边部分安装到主体上，在第一端部处封闭孔。 指示部件或环被固定到主体和反向屈曲盘的组合。 指示环具有环形周边部分，其大致与逆向压曲破裂盘的环形周边部分对准。 可移动中心突出部分安装在指示部件或环内。 铰链将中央突片部分连接到指示环。 反向弯曲盘的凹面朝向中央突出部。 反向弯曲盘的凸面面对孔内的压力。 当孔中的压力超过预选的最大压力值时，盘反转以接合和移动中央突片，从而可视地显示孔内存在过压状况。

    ENVIRONMENT MONITORING AND RECORDING TAG WITH REMOTE SENSING CAPABILITY
    25.
    发明申请
    ENVIRONMENT MONITORING AND RECORDING TAG WITH REMOTE SENSING CAPABILITY 有权
    具有远程感测能力的环境监测和记录标签

    公开(公告)号：US20100170352A1

    公开(公告)日：2010-07-08

    申请号：US12722958

    申请日：2010-03-12

    申请人： Michael Petersen ,  Alan Wilson ,  Dean Brotzel

    发明人： Michael Petersen ,  Alan Wilson ,  Dean Brotzel

    IPC分类号： G01D11/24 ,  G06K19/06

    CPC分类号： G01D21/00 ,  G01D9/005 ,  G06K19/0717

    摘要： A tag includes an integrated circuit thereon, including memory, antenna means for RF transmission of data acquired by the integrated circuit, a sensor sensing environmental conditions to which the sensor is subjected, the sensor providing signals based on the environmental conditions to the integrated circuit, a thermistor device of increasing the accuracy of the tag by confining on-board calculation data to a resistance domain and leaving conversion of the data to a temperature domain for an external device once the data is retrieved from the tag's memory.

    摘要翻译： 标签包括其上的集成电路，包括存储器，用于RF传输由集成电路获取的数据的天线装置，感测传感器经受的环境条件的传感器，传感器基于环境条件向集成电路提供信号， 一种热敏电阻器件，其通过将板上计算数据限制在电阻域上，并且一旦从标签的存储器检索到数据，就将数据转换为外部设备的温度域，从而提高了标签的精度。

    Method of manufacturing an electrical component
    26.
    发明申请
    Method of manufacturing an electrical component 有权
    制造电气部件的方法

    公开(公告)号：US20070173048A1

    公开(公告)日：2007-07-26

    申请号：US10581552

    申请日：2004-12-01

    申请人： Alan Wilson ,  Peter Vincent ,  Richard Muscat

    发明人： Alan Wilson ,  Peter Vincent ,  Richard Muscat

    IPC分类号： H01L21/44

    CPC分类号： C23F4/00 ,  G01N17/04 ,  H05K1/162 ,  H05K1/165 ,  H05K3/0038 ,  H05K3/027 ,  H05K2201/0187 ,  H05K2201/10151

    摘要： There is disclosed a method of manufacturing an electrical component, involving bonding a thin metal foil to an insulating substrate and thereby forming a component blank, and laser machining at least the metal foil of said component blank to produce at least one trench for defining one or more foil tracks, said trench being at least equal in depth to the thickness of the foil so as to prevent current flow across the trench.

    摘要翻译： 公开了一种制造电气部件的方法，包括将薄金属箔接合到绝缘基板上，从而形成部件坯料，并激光加工至少所述部件坯件的金属箔，以产生至少一个沟槽，用于限定一个或 更多的箔轨道，所述沟槽至少与箔的厚度相等，以防止电流流过沟槽。

    Wire electrical discharge machined rupture disk and method
    29.
    发明授权
    Wire electrical discharge machined rupture disk and method 有权
    线放电加工破裂盘及方法

    公开(公告)号：US08671550B1

    公开(公告)日：2014-03-18

    申请号：US11956047

    申请日：2007-12-13

    申请人： Alan Wilson

    发明人： Alan Wilson

    IPC分类号： B23P13/04

    CPC分类号： F16K17/40 ,  B23H7/02 ,  B23H7/26 ,  B23H9/00 ,  F16K17/16 ,  Y10T29/49995 ,  Y10T137/0491

    摘要： The present invention provides an improved method of manufacturing a rupture disk and specifically of forming a score on a rupture disk. The method of the present invention includes the rotating of a rupture disk blank relative to an electrical discharge machining or “EDM” cutting wire and the simultaneous moving of the EDM cutting wire toward the axis of the disk while maintaining the wire in a selected position such as generally parallel to the disk peripheral skirt or flange. The rotation of the disk and the movement of the EDM wire can be precisely controlled with the motion system of a commercially available EDM machine. With the present invention, a precise score is cut a partial distance through the disk thickness and preferably on the convex side of the dome, near the transition from the dome to the flange and in a generally “c” shaped pattern. The formed score creates a pattern of weakness so that the disk will open in either of the forward or reverse buckling direction. Score patterns other than the “c” shaped pattern could be cut.

    摘要翻译： 本发明提供一种改进的制造破裂盘的方法，特别是在破裂盘上形成刻痕。 本发明的方法包括相对于放电加工或“EDM”切割线旋转破裂盘坯料，同时将EDM切割线沿着盘的轴线移动，同时将线材保持在选定位置，例如 大致平行于盘周边裙缘或凸缘。 可以使用市售的EDM机的运动系统精确地控制盘的旋转和EDM线的移动。 利用本发明，通过盘的厚度，优选地在圆顶的凸面侧，在从圆顶到凸缘的过渡附近，以大致“c”形的图案，切割出精确得分。 形成的分数产生弱点，使得盘将在向前或向后的屈曲方向上打开。 除了“c”形图案之外的分数图案可以被切割。

    Rupture panel
    30.
    发明授权
    Rupture panel 有权
    破裂面板

    公开(公告)号：US08322360B2

    公开(公告)日：2012-12-04

    申请号：US12852975

    申请日：2010-08-09

    申请人： Alan Wilson

    发明人： Alan Wilson

    IPC分类号： F16K17/16 ,  F16K17/40

    CPC分类号： B65D90/36 ,  E04B1/98 ,  F16K17/16 ,  Y10T137/1692 ,  Y10T137/1714 ,  Y10T137/1744

    摘要： A rupture panel of three layers employs a lower layer (e.g. foam) that is adhesive, a middle layer (e.g. metallic) and a hold down layer. The middle layer has a weakened portion (scoring, openings, for example) that defines the panel burst pressure. A part of the lower layer does not connect to the middle layer. That part that does not connect to the middle layer adheres to the hold down layer. The hold down layer can be in the form of a ring with an open center, the weakened portion of the middle layer occupying a position within the open center of the hold down layer.

    摘要翻译： 三层的破裂板采用粘合剂，中间层（例如金属）和压紧层的下层（例如泡沫）。 中间层具有限定面板爆裂压力的弱化部分（例如刻痕，开口）。 下层的一部分不连接到中间层。 不连接到中间层的部分遵守按压层。 压紧层可以是具有开放中心的环的形式，中间层的弱化部分占据压紧层的开放中心内的位置。