公开(公告)号：US20190310221A1

公开(公告)日：2019-10-10

申请号：US16441282

申请日：2019-06-14

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Michael Marquant ,  Samuel Evgin ,  Melanie Klein

IPC: G01N27/327

Abstract: A method for determining a concentration of at least one analyte in bodily fluid, comprising: a signal generation step, wherein an excitation voltage signal is generated by a signal generator, wherein the excitation voltage signal comprises a poly frequent alternating current (AC) voltage and a direct current (DC) voltage profile, wherein the poly frequent AC voltage comprises at least two frequencies; a signal application step, wherein the excitation voltage signal is applied to at least two measurement electrodes; a measurement step, wherein a response is measured by using the measurement electrodes; an evaluation step, wherein an AC current response for each frequency and a DC current response are evaluated from the response; a determination step, wherein the concentration of the analyte is determined from the DC current response and from one or both of the phase and impedance information by using at least one predetermined relationship.

公开(公告)号：US20170251922A1

公开(公告)日：2017-09-07

申请号：US15486948

申请日：2017-04-13

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Bernd Roesicke ,  Karin Obermaier ,  Stefan Lindegger ,  Andreas Menke ,  Joerg Scherer ,  Karin Schwind ,  Otto Gaa ,  Gregor Bainczyk ,  Michael Marquant ,  Sandro Niederhauser ,  Michael Schoemaker ,  Martin Mueri

IPC: A61B5/00 ,  A61B90/98 ,  A61B5/1459 ,  A61B5/145 ,  A61B5/1495 ,  A61B5/1486

CPC classification number: A61B5/0031 ,  A61B5/0002 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1459 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/6849 ,  A61B5/7232 ,  A61B5/742 ,  A61B90/98 ,  A61B2560/0209 ,  A61B2560/0219 ,  A61B2560/0481

Abstract: The analyte concentration, such as glucose, in a human or animal body is measured with an implantable sensor that generates measurement signals. The measurement signals are compressed through statistical techniques to produced compressed measurement data that can is easier to process and communicate. A base station carries the implantable sensor along with a signal processor, memory, and a transmitter. A display device is also disclosed that can receive the compressed measurement data from the base station for further processing and display.

公开(公告)号：US20140345130A1

公开(公告)日：2014-11-27

申请号：US14452825

申请日：2014-08-06

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Michael Marquant ,  Gregor Bainczyk

IPC: G01N27/327 ,  H01R43/16 ,  C25D5/48

CPC classification number: G01N27/4166 ,  A61B5/14532 ,  A61B5/14865 ,  C25D5/48 ,  G01N27/301 ,  G01N27/327 ,  G01N27/3272 ,  G01N33/4833 ,  H01R43/16 ,  Y10T29/49204

Abstract: The invention relates to an electrochemical sensor for the determination of a concentration of at least one analyte in a medium, in particular a body tissue and/or a body fluid, to an apparatus that includes the electrochemical sensor, and to a use of the electrochemical sensor, and finally to a method for producing it. The electrochemical sensor has an isolation element and at least two electrodes. The at least two electrodes comprise at least one working electrode and at least one further electrode, in particular at least one counter electrode and/or at least one reference electrode. The at least two electrodes run parallel to one another and form an electrochemical measuring cell of the electrochemical sensor.

Abstract translation: 本发明涉及一种电化学传感器，用于确定介质中的至少一种分析物，特别是身体组织和/或体液的浓度，包括电化学传感器的装置，以及使用电化学 传感器，最后是一种生产它的方法。 电化学传感器具有隔离元件和至少两个电极。 至少两个电极包括至少一个工作电极和至少一个另外的电极，特别是至少一个对电极和/或至少一个参考电极。 至少两个电极彼此平行地延伸并形成电化学传感器的电化学测量单元。

公开(公告)号：US20140066730A1

公开(公告)日：2014-03-06

申请号：US14076428

申请日：2013-11-11

Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.

Inventor： Bernd Roesicke ,  Karin Obermaier ,  Stefan Lindegger ,  Andreas Menke ,  Joerg Scherer ,  Karin Schwind ,  Otto Gaa ,  Gregor Bainczyk ,  Michael Marquant ,  Sandro Niederhauser ,  Michael Schoemaker ,  Martin Mueri

IPC: A61B5/145

CPC classification number: A61B5/0031 ,  A61B5/0002 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1459 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/6849 ,  A61B5/7232 ,  A61B5/742 ,  A61B90/98 ,  A61B2560/0209 ,  A61B2560/0219 ,  A61B2560/0481

Abstract: The analyte concentration, such as glucose, in a human or animal body is measured with an implantable sensor that generates measurement signals. The measurement signals are compressed through statistical techniques to produced compressed measurement data that can is easier to process and communicate. A base station carries the implantable sensor along with a signal processor, memory, and a transmitter. A display device is also disclosed that can receive the compressed measurement data from the base station for further processing and display.

Abstract translation: 使用可产生测量信号的可植入传感器来测量人或动物体内的分析物浓度，例如葡萄糖。 测量信号通过统计技术进行压缩，以产生可以更容易处理和通信的压缩测量数据。 基站与信号处理器，存储器和发射器一起携带可植入传感器。 还公开了可以从基站接收压缩的测量数据以进一步处理和显示的显示装置。