公开(公告)号：US12247989B2

公开(公告)日：2025-03-11

申请号：US17279890

申请日：2019-09-23

Applicant: Siemens Healthcare Diagnostics Inc.

Inventor： Aaron Kauffmann

IPC: G01N33/86 ,  B01L3/00 ,  G01N21/03 ,  G01N21/27 ,  G01N21/75

Abstract: Devices and methods for calculating various coagulation characteristics associated with a patients liquid test sample. The presently disclosed and claimed inventive concept(s) relate to an improved device(s) and method(s) for conducting coagulation assays on a patients liquid test sample, including, without limitation, a patients whole blood sample.

公开(公告)号：US20230383865A1

公开(公告)日：2023-11-30

申请号：US18252842

申请日：2021-11-12

Applicant: Siemens Healthcare Diagnostics Inc.

Inventor： Aaron Kauffmann

IPC: F16K99/00

CPC classification number: F16K99/0015 ,  F16K99/0059

Abstract: A microfluidic device has a first substrate, a resilient diaphragm, an actuator, and a second substrate. The first substrate has an opening extending therethrough. The resilient diaphragm is secured to a second side and surrounds the opening. The actuator is secured to a first side and surrounds the opening. The first substrate, the resilient diaphragm, and the actuator cooperate to form a gas-tight chamber. The second substrate has a channel formed therein having a first end and a second end. The second substrate is secured to the first substrate. A volume of gas disposed in the gas-tight chamber pressurizes the gas-tight chamber and expands the resilient diaphragm such that the resilient diaphragm is disposed in the channel between the first end and the second end. The resilient diaphragm retracts from the channel to open the channel from the first end and the second when the gas-tight chamber is depressurized.

公开(公告)号：US20230347338A1

公开(公告)日：2023-11-02

申请号：US18245752

申请日：2021-09-22

Applicant: Siemens Healthcare Diagnostics Inc.

Inventor： Aaron Kauffmann ,  Manish Deshpande

IPC: B01L3/00

CPC classification number: B01L3/5023 ,  B01L2200/04 ,  B01L2300/022 ,  B01L2300/027 ,  B01L2300/0609 ,  B01L2300/0654 ,  B01L2300/0825

Abstract: A reagent strip is described. The reagent strip includes a substrate and at least one reagent pad positioned on the substrate. The substrate has a storage unit storing an authentication code. The authentication code has a lot value and a secondary value related to the lot value by a predetermined function assigned to the lot value.

公开(公告)号：US20220143604A1

公开(公告)日：2022-05-12

申请号：US17593310

申请日：2020-03-12

Applicant: Siemens Healthcare Diagnostics Inc.

Inventor： Aaron Kauffmann ,  Jeffrey Mayfield ,  David Ledden

IPC: B01L3/00

Abstract: Microfluidic devices, method for making and using same are disclosed. The microfluidic device can be made by applying a reagent in liquid form into a sample treatment site within a substrate base. The substrate base has hydrophilic properties bordering a flow channel, and has an application site, the sample treatment site and an analytical site. The flow channel is sized and configured so as to draw a sample applied into the application site to the analytical site through the sample treatment site by capillary action. The reagent is freeze-dried within the sample treatment site.

公开(公告)号：US20220137031A1

公开(公告)日：2022-05-05

申请号：US17435471

申请日：2019-12-05

Applicant: Siemens Healthcare Diagnostics Inc.

Inventor： Jennifer Samproni ,  Aaron Kauffmann ,  David Ledden

IPC: G01N33/52 ,  B01L3/00 ,  G01N21/78

Abstract: A blood testing assembly and method are described. In the method, a blood testing device having a plasma separation membrane and a reagent is connected to a syringe containing blood having blood cells and plasma. A blood sample of the blood is passed from the syringe through a plasma separation membrane within the blood testing device to separate the plasma from the blood cells. A reagent is saturated with the plasma, and then the reagent is colorimetrically analyzed to determine a degree of hemolysis within the blood sample.

公开(公告)号：US20210302430A1

公开(公告)日：2021-09-30

申请号：US17259361

申请日：2019-06-20

Applicant: Siemens Healthcare Diagnostics Inc.

Inventor： Aaron Kauffmann

IPC: G01N33/58 ,  G01N33/70 ,  B01L3/00

Abstract: Devices, kits, and methods related to embodiments of an improved liquid test sample injection device comprising a sample mixture that comprises at least one sample flag compound for detecting the presence or non-presence of a patient's liquid test sample upon being interrogated by a pre-determined wavelength of light.

公开(公告)号：US20180321271A1

公开(公告)日：2018-11-08

申请号：US15970272

申请日：2018-05-03

Applicant: Siemens Healthcare Diagnostics Inc.

Inventor： Aaron Kauffmann

IPC: G01N35/10

CPC classification number: G01N35/1016 ,  G01N35/00584 ,  G01N35/1002

Abstract: Devices, kits, and methods related to embodiments of an improved liquid test sample injection device for use in diagnostic assays.