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公开(公告)号：US20230211336A1
公开(公告)日：2023-07-06
申请号：US17996669
申请日：2021-04-20
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor： Aaron Kauffmann
CPC classification number: B01L3/502 , G01N33/721 , B01L2200/16 , B01L2300/0816 , B01L2300/0838 , B01L2300/0858
Abstract: Analytical assay reaction cartridges are disclosed that include a reagent tray containing a liquid reagent disposed therein and a flexible cover removably attached thereto. The flexible cover has a portion that extends beyond the reagent tray and that forms a tab portion extends through an opening in a lid member of the cartridge in order to facilitate removal of at least a portion of the cover and release of the liquid reagent. Also disclosed are analytical assay reaction kits that include the cartridges and diagnostic instruments for use with the analytical assay reaction cartridges/kits, as well as methods of making and using the cartridges/kits.
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公开(公告)号：US20220034914A1
公开(公告)日：2022-02-03
申请号：US17279890
申请日：2019-09-23
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor： Aaron Kauffmann
Abstract: Devices and methods for calculating various coagulation characteristics associated with a patients liquid test sample. The presently disclosed and claimed inventive concept(s) relate to an improved device(s) and method(s) for conducting coagulation assays on a patients liquid test sample, including, without limitation, a patients whole blood sample.
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公开(公告)号：US20210389307A1
公开(公告)日：2021-12-16
申请号：US17279958
申请日：2019-09-20
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor： Julie Chaney , Jon Stradinger , Aaron Kauffmann , Jeffrey Mayfield , Chris Zimmerle
IPC: G01N33/53 , G01N21/27 , G01N21/78 , G01N21/82 , G01N33/543
Abstract: Devices and methods for the hook effect detection associated with analytes of interest in the conductance of one or more diagnostic assays, including, without limitation, immunoassays.
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公开(公告)号：USD934446S1
公开(公告)日：2021-10-26
申请号：US29683615
申请日：2019-03-14
Applicant: Siemens Healthcare Diagnostics Inc.
Designer： Aaron Kauffmann
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公开(公告)号：US11994517B2
公开(公告)日：2024-05-28
申请号：US18000944
申请日：2021-06-16
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor： Aaron Kauffmann , Jon Stradinger
IPC: G01N33/543 , B01L3/00 , G01N33/68
CPC classification number: G01N33/54326 , B01L3/502761 , G01N33/54386 , G01N33/6872 , B01L2200/04 , B01L2200/0668 , B01L2200/16 , B01L2400/043 , G01N2333/4737
Abstract: Analytical assay reaction cartridges, kits containing same, and methods of production and use thereof are disclosed. These cartridges include a magnetic assembly that surrounds at least a portion of a sample read window on the cartridge. The cartridge also includes an analytical reagent positioned therewithin, wherein the analytical reagent comprises magnetic beads coated with at least one anti-red blood cell antibody.
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Patent Agency Ranking
6.发明授权公开(公告)号：US11971415B2
公开(公告)日：2024-04-30
申请号：US17259361
申请日：2019-06-20
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor： Aaron Kauffmann
CPC classification number: G01N33/58 , B01L3/502 , G01N33/70 , B01L2300/16 , B01L2400/0406
Abstract: Devices, kits, and methods related to embodiments of an improved liquid test sample injection device comprising a sample mixture that comprises at least one sample flag compound for detecting the presence or non-presence of a patient's liquid test sample upon being interrogated by a pre-determined wavelength of light.
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公开(公告)号：US11850583B2
公开(公告)日：2023-12-26
申请号：US17617881
申请日：2020-06-05
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor： Aaron Kauffmann , David Ledden
IPC: B01L3/00
CPC classification number: B01L3/502 , B01L2200/0605 , B01L2400/0406
Abstract: Devices, kits, and methods separating and metering a plasma sample from a patient's liquid test sample.
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公开(公告)号：US11460476B2
公开(公告)日：2022-10-04
申请号：US17435433
申请日：2020-02-26
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor： Aaron Kauffmann , David Ledden , Chris Zimmerle , Jon Stradinger
Abstract: Devices, kits, and methods are disclosed for use in detecting a concentration of an analyte of interest in a patient's liquid test sample. The devices, kits, and methods employ the use of one or more solid reagent zones that includes at least one analytical reagent for detection of an analyte of interest. The solid reagent zone(s) also includes at least one dye for determining whether results obtained from the diagnostic assay for the at least one analyte of interest are biased or inaccurate due to a loss of volume of a liquid reagent during the dispensing of the liquid reagent.
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公开(公告)号：US11020743B2
公开(公告)日：2021-06-01
申请号：US16968717
申请日：2019-02-13
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor： Aaron Kauffmann
Abstract: Devices, kits, and methods for conducting a plurality of diagnostic assays on a patient's single liquid test sample within a single reaction cassette.
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公开(公告)号：US11859734B2
公开(公告)日：2024-01-02
申请号：US18252842
申请日：2021-11-12
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor： Aaron Kauffmann
IPC: F16K99/00
CPC classification number: F16K99/0015 , F16K99/0059
Abstract: A microfluidic device has a first substrate, a resilient diaphragm, an actuator, and a second substrate. The first substrate has an opening extending therethrough. The resilient diaphragm is secured to a second side and surrounds the opening. The actuator is secured to a first side and surrounds the opening. The first substrate, the resilient diaphragm, and the actuator cooperate to form a gas-tight chamber. The second substrate has a channel formed therein having a first end and a second end. The second substrate is secured to the first substrate. A volume of gas disposed in the gas-tight chamber pressurizes the gas-tight chamber and expands the resilient diaphragm such that the resilient diaphragm is disposed in the channel between the first end and the second end. The resilient diaphragm retracts from the channel to open the channel from the first end and the second when the gas-tight chamber is depressurized.
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