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公开(公告)号:US20240201210A1
公开(公告)日:2024-06-20
申请号:US18555880
申请日:2022-04-20
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor: Manish Deshpande , Ethan Warner , Emma Orton
CPC classification number: G01N35/00732 , G01N35/00871 , G06K19/0723 , G01N2035/00742
Abstract: An automated analyzer is described. The analyzer includes a housing, a consumable insert, a consumable support device, a reader and a control system. The housing has a sample port. The consumable insert has a consumable insert type and an identification component and receives a consumable. The consumable support device is disposed within the sample port, supports the consumable insert, and is moveable to a testing position within the internal cavity. The consumable support device has an identifier component configured to identify the consumable insert type based in part on the identification component and configured to output a first data signal indicative of the consumable insert type. The reader outputs a second data signal indicative of a reading from the consumable. The control system receives the first and second data signals, and interprets the second data signal based on the first data signal.
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公开(公告)号:US20160038938A1
公开(公告)日:2016-02-11
申请号:US14775338
申请日:2014-03-13
Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Inventor: Dafeng Chen , James E. Rasmussen , Manish Deshpande
IPC: B01L3/00
CPC classification number: B01L3/5027 , B01L3/502715 , B01L3/502738 , B01L3/523 , B01L2200/10 , B01L2200/16 , B01L2300/0672 , B01L2300/0816 , B01L2300/0867 , B01L2300/123 , B01L2400/0481 , B01L2400/0683 , F16K99/003 , F16K2099/008 , F16K2099/0084
Abstract: A microfluidic product pouch assembly may be used in a microfluidic chip. The microfluidic product pouch may include a pouch surrounding an inner chamber and having a rupturing portion and an inner membrane positioned within the inner chamber. The inner membrane may separate the inner chamber into a first cavity and a second cavity. A reagent may be positioned within the first cavity and/or the second cavity. The microfluidic product pouch assembly may also include a rupturing structure. The rupturing structure may be configured to selectively break the rupturing portion of the microfluidic product pouch.
Abstract translation: 微流体产品袋组件可用于微流体芯片。 微流体产品袋可以包括围绕内室的袋,并且具有破裂部分和位于内室内的内膜。 内膜可以将内室分离成第一腔和第二腔。 试剂可以定位在第一腔和/或第二腔内。 微流体产品袋组件还可以包括破裂结构。 破裂结构可以被配置为选择性地破坏微流体产品袋的破裂部分。
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公开(公告)号:US20230347338A1
公开(公告)日:2023-11-02
申请号:US18245752
申请日:2021-09-22
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor: Aaron Kauffmann , Manish Deshpande
IPC: B01L3/00
CPC classification number: B01L3/5023 , B01L2200/04 , B01L2300/022 , B01L2300/027 , B01L2300/0609 , B01L2300/0654 , B01L2300/0825
Abstract: A reagent strip is described. The reagent strip includes a substrate and at least one reagent pad positioned on the substrate. The substrate has a storage unit storing an authentication code. The authentication code has a lot value and a secondary value related to the lot value by a predetermined function assigned to the lot value.
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公开(公告)号:US20230324307A1
公开(公告)日:2023-10-12
申请号:US18040901
申请日:2021-08-10
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor: Manish Deshpande , Willis Howard III
CPC classification number: G01N21/78 , F21V19/0025 , G06T7/0002 , G06T7/90 , H04N23/56 , H04N23/74 , F21Y2115/10
Abstract: A reagent analyzer having a circuit board, an imaging system and a processor is disclosed. The circuit board has a substrate, and a plurality of conductive leads. The substrate has a first and a second major surface. The first major surface is opposite the second major surface. The substrate has an opening extending between the first major surface and the second major surface. The reagent analyzer also includes an imaging system having a field of view extending through the opening formed in the substrate and configured to capture an image of a wet reagent test device positioned at a read position in the field of view, the image having a plurality of pixels. The processor is configured to receive the image, and to analyze pixels of the image to determine a presence or an absence of a target constituent being in a sample applied to the wet reagent pad.
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公开(公告)号:US20220023857A1
公开(公告)日:2022-01-27
申请号:US17299821
申请日:2019-12-05
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor: Jennifer Samproni , Manish Deshpande
Abstract: A device including a housing, a zone and a means for testing a fluid sample within the housing is disclosed. The housing is constructed of a fluid impermeable material, and defines a first fluid port, and a second fluid port. The first fluid port is configured to connect to a fluid collection device to receive a fluid sample from the fluid collection device into the housing. The second port is configured to pass the fluid sample from the housing into a testing instrument. The zone is formed in the housing. The zone is constructed of a material that allows an analysis of the fluid sample positioned within the housing, and located adjacent to the zone.
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公开(公告)号:US20230375480A1
公开(公告)日:2023-11-23
申请号:US18246548
申请日:2021-09-24
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor: Siraj Issani , Simit Pradhan , Sudipa Bhattacharya , Manish Deshpande
IPC: G01N21/84
CPC classification number: G01N21/8483
Abstract: An image analysis system, a method and a point of care device are provided for determining, from an image of a cassette containing a sample, a concentration of one or more target analytes in the sample. The method includes identifying a region of interest (ROI) from the image corresponding to a result viewing area of the cassette, generating a unidimensional (1D) profile of the ROI, and probabilistically determining from the 1D profile, the concentration of the target analyte(s) in the sample based on a statistical model having one or more parameters of the 1D profile varying with respect to time and/or the concentration of the target analyte(s) in the sample.
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公开(公告)号:US20230324422A1
公开(公告)日:2023-10-12
申请号:US18042847
申请日:2021-08-30
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor: Manish Deshpande
IPC: G01N35/00
CPC classification number: G01N35/00693 , G01N35/00732 , G01N35/00029 , G01N2035/00752 , G01N2035/00831 , G01N2035/00108
Abstract: A reagent analyzer comprising an imaging system having a first field of view of a reagent test device and a second field of view of a fluid sample information indicator, and configured to capture a first image depicting the reagent test device and a second image depicting the information indicator; a mirror moveable between a first position outside the first field of view and a second position inside the first field of view and located between the imaging system and the reagent test device, the mirror in the second position reflecting light to produce the second field of view; and a processor executing instructions to: receive the first and second images; analyze the first image to determine calibration information from the information indicator; and analyze the second image to determine constituent presence/absence in the fluid sample applied to the reagent test device, using, in part, the determined calibration information.
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公开(公告)号:US11235321B2
公开(公告)日:2022-02-01
申请号:US16598363
申请日:2019-10-10
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor: Dafeng Chen , James E. Rasmussen , Manish Deshpande
IPC: B01L3/00
Abstract: A microfluidic product pouch assembly may be used in a microfluidic chip. The microfluidic product pouch may include a pouch surrounding an inner chamber and having a rupturing portion and an inner membrane positioned within the inner chamber. The inner membrane may separate the inner chamber into a first cavity and a second cavity. A reagent may be positioned within the first cavity and/or the second cavity. The microfluidic product pouch assembly may also include a rupturing structure. The rupturing structure may be configured to selectively break the rupturing portion of the microfluidic product pouch.
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公开(公告)号:US20200038855A1
公开(公告)日:2020-02-06
申请号:US16598363
申请日:2019-10-10
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor: Dafeng Chen , James E. Rasmussen , Manish Deshpande
Abstract: A microfluidic product pouch assembly may be used in a microfluidic chip. The microfluidic product pouch may include a pouch surrounding an inner chamber and having a rupturing portion and an inner membrane positioned within the inner chamber. The inner membrane may separate the inner chamber into a first cavity and a second cavity. A reagent may be positioned within the first cavity and/or the second cavity. The microfluidic product pouch assembly may also include a rupturing structure. The rupturing structure may be configured to selectively break the rupturing portion of the microfluidic product pouch.
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公开(公告)号:US10441951B2
公开(公告)日:2019-10-15
申请号:US14775338
申请日:2014-03-13
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor: Dafeng Chen , James E. Rasmussen , Manish Deshpande
Abstract: A microfluidic product pouch assembly may be used in a microfluidic chip. The microfluidic product pouch may include a pouch surrounding an inner chamber and having a rupturing portion and an inner membrane positioned within the inner chamber. The inner membrane may separate the inner chamber into a first cavity and a second cavity. A reagent may be positioned within the first cavity and/or the second cavity. The microfluidic product pouch assembly may also include a rupturing structure. The rupturing structure may be configured to selectively break the rupturing portion of the microfluidic product pouch.
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