公开(公告)号：US20240052406A1

公开(公告)日：2024-02-15

申请号：US18364849

申请日：2023-08-03

Applicant: Singular Genomics Systems, Inc.

Inventor： Daan Witters ,  Eli N. Glezer

IPC: C12Q1/6844 ,  C12Q1/6834

CPC classification number: C12Q1/6844 ,  C12Q1/6834

Abstract: Disclosed herein, inter alia, are methods for increasing monoclonal nucleic acid amplification products on a solid support.

公开(公告)号：US11859244B2

公开(公告)日：2024-01-02

申请号：US18185786

申请日：2023-03-17

Applicant: Singular Genomics Systems, Inc

Inventor： Ryan Shultzaberger ,  Allen Lipson ,  Daan Witters

IPC: C12Q1/6874 ,  C12Q1/6876 ,  C12Q1/6855

CPC classification number: C12Q1/6855 ,  C12Q1/6874 ,  C12Q1/6876

Abstract: Disclosed herein, inter alia, are polynucleotides, supports, kits, and methods of use thereof for amplifying, immobilizing, and sequencing polynucleotides.

公开(公告)号：US20210277461A1

公开(公告)日：2021-09-09

申请号：US17194023

申请日：2021-03-05

Applicant: SINGULAR GENOMICS SYSTEMS, INC.

Inventor： Eli N. Glezer ,  Martin Maria Fabani ,  Timothy Looney ,  Sabrina Shore ,  Ryan Shultzaberger ,  Daan Witters

IPC: C12Q1/6869 ,  C12Q1/6855

Abstract: Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.

公开(公告)号：US20240392369A1

公开(公告)日：2024-11-28

申请号：US18776983

申请日：2024-07-18

Applicant: Singular Genomics Systems, Inc.

Inventor： Daan Witters ,  Eli N. Glezer ,  Andrew King ,  Sabrina Shore ,  Ryan Shultzaberger

IPC: C12Q1/6874

Abstract: Disclosed herein, inter alia, are compositions and methods for amplification and sequencing of nucleic acids.

公开(公告)号：US20240150826A1

公开(公告)日：2024-05-09

申请号：US18412289

申请日：2024-01-12

Applicant: Singular Genomics Systems, Inc.

Inventor： Eli N. Glezer ,  Martin Maria Fabani ,  Sabrina Shore ,  Daan Witters

IPC: C12Q1/6869 ,  C12Q1/6855

CPC classification number: C12Q1/6869 ,  C12Q1/6855

Abstract: Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.

公开(公告)号：US11802307B2

公开(公告)日：2023-10-31

申请号：US18185783

申请日：2023-03-17

Applicant: Singular Genomics Systems, Inc

Inventor： Ryan Shultzaberger ,  Allen Lipson ,  Daan Witters

IPC: C12Q1/6855

CPC classification number: C12Q1/6855

Abstract: Disclosed herein, inter alia, are polynucleotides, supports, kits, and methods of use thereof for amplifying, immobilizing, and sequencing polynucleotides.

公开(公告)号：US11795505B2

公开(公告)日：2023-10-24

申请号：US18119393

申请日：2023-03-09

Applicant: Singular Genomics Systems, Inc.

Inventor： Mark Kalaj ,  Daan Witters

IPC: C12Q1/6874

CPC classification number: C12Q1/6874

Abstract: Disclosed herein, inter alia, are degradable nanoparticles, nanoarrays, and methods of use thereof in nucleic acid sequencing.

公开(公告)号：US20230203579A1

公开(公告)日：2023-06-29

申请号：US18111422

申请日：2023-02-17

Applicant: Singular Genomics Systems, Inc.

Inventor： Eli N. Glezer ,  Vahid Karimkhani ,  Shahed Kay ,  Mohammad Vatankhah Varnosfaderani ,  Daan Witters

IPC: C12Q1/6874 ,  C12Q1/6876 ,  C40B40/06

CPC classification number: C12Q1/6874 ,  C12Q1/6876 ,  C40B40/06

Abstract: Disclosed herein, inter alia, are nanoarrays and methods of use thereof.

公开(公告)号：US11649452B2

公开(公告)日：2023-05-16

申请号：US18046458

申请日：2022-10-13

Applicant: SINGULAR GENOMICS SYSTEMS, INC.

Inventor： Eli N. Glezer ,  Daan Witters ,  Niek Van Wietmarschen

IPC: C12N15/10 ,  C12Q1/6874 ,  C12Q1/6806

CPC classification number: C12N15/1068 ,  C12Q1/6874 ,  C12Q1/6806

Abstract: Disclosed herein, inter alia, are methods and compositions for sequencing a plurality of template nucleic acids.

公开(公告)号：US20220396834A1

公开(公告)日：2022-12-15

申请号：US17817960

申请日：2022-08-05

Applicant: Singular Genomics Systems, Inc.

Inventor： Eli N. Glezer ,  Vahid Karimkhani ,  Shahed Kay ,  Mohammad Vatankhah Varnosfaderani ,  Daan Witters

IPC: C12Q1/6874 ,  C12Q1/6876

Abstract: Disclosed herein, inter alia, are nanoarrays and methods of use thereof.