公开(公告)号：US20210393439A1

公开(公告)日：2021-12-23

申请号：US17402244

申请日：2021-08-13

Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE

Inventor： Malik Y. KAHOOK

IPC: A61F9/013 ,  A61F9/007 ,  A61B17/3209

Abstract: A microsurgical device and methods of its use can be used for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. A dual-blade device can be used for cutting the trabecular meshwork (“TM”) in the eye. The device tip provides entry into the Schlemm's canal via its size (i.e., for example, 0.2-0.3 mm width) and configuration where a ramp elevates the TM away from the outer wall of the Schlemm's canal and guides the TM to first and second lateral elements for creating first and second incisions through the TM. The dimensions and configuration of the blade is such that an entire strip of TM is removed without leaving TM leaflets behind and without causing collateral damage to adjacent tissues.

公开(公告)号：US20200375800A1

公开(公告)日：2020-12-03

申请号：US16997663

申请日：2020-08-19

Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE

Inventor： Malik Y. KAHOOK

IPC: A61F9/013 ,  A61F9/007 ,  A61B17/3209

Abstract: A microsurgical device and methods of its use can be used for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. A dual-blade device can be used for cutting the trabecular meshwork (“TM”) in the eye. The device tip provides entry into the Schlemm's canal via its size (i.e., for example, 0.2-0.3 mm width) and configuration where a ramp elevates the TM away from the outer wall of the Schlemm's canal and guides the TM to first and second lateral elements for creating first and second incisions through the TM. The dimensions and configuration of the blade is such that an entire strip of TM is removed without leaving TM leaflets behind and without causing collateral damage to adjacent tissues.

公开(公告)号：US20200129337A1

公开(公告)日：2020-04-30

申请号：US16678785

申请日：2019-11-08

Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE

Inventor： Malik Y. KAHOOK

IPC: A61F9/013 ,  A61B17/3209 ,  A61F9/007

Abstract: A microsurgical device and methods of its use can be used for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. A dual-blade device can be used for cutting the trabecular meshwork (“TM”) in the eye. The device tip provides entry into the Schlemm's canal via its size (i.e., for example, 0.2-0.3 mm width) and configuration where a ramp elevates the TM away from the outer wall of the Schlemm's canal and guides the TM to first and second lateral elements for creating first and second incisions through the TM. The dimensions and configuration of the blade is such that an entire strip of TM is removed without leaving TM leaflets behind and without causing collateral damage to adjacent tissues.

公开(公告)号：US20180036169A1

公开(公告)日：2018-02-08

申请号：US15719986

申请日：2017-09-29

Applicant: The Regents of the University of Colorado, a body corporate

Inventor： Malik Y. KAHOOK

IPC: A61F9/00 ,  A61H23/02 ,  A61N1/36 ,  A61N1/372 ,  A61F7/12 ,  A61N5/06 ,  A61N7/00 ,  A61N2/00 ,  A61N1/05 ,  A61F9/007 ,  A61N1/378

CPC classification number: A61F9/0017 ,  A61F7/12 ,  A61F9/0026 ,  A61F9/00772 ,  A61H23/02 ,  A61N1/0551 ,  A61N1/36 ,  A61N1/36046 ,  A61N1/36057 ,  A61N1/37205 ,  A61N1/37211 ,  A61N1/37229 ,  A61N1/3787 ,  A61N2/004 ,  A61N5/0603 ,  A61N7/00 ,  A61N2007/0004

Abstract: A device for inducing production of tears may include a body extending from a proximal end to a distal end. The body may be configured for insertion through a puncta of a subject. The device also may include a stimulus delivery mechanism positioned between the proximal end and the distal end and an induction coil operably coupled to the stimulus delivery mechanism. Further, the device may include an external controller wirelessly coupled to the induction coil for inductively transferring energy to the induction coil.

公开(公告)号：US20170216097A1

公开(公告)日：2017-08-03

申请号：US15484041

申请日：2017-04-10

Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE

Inventor： Malik Y. KAHOOK

IPC: A61F9/013 ,  A61F9/007 ,  A61B17/3209

CPC classification number: A61F9/0133 ,  A61B17/3209 ,  A61F9/00736 ,  A61F9/00781

Abstract: A microsurgical device and methods of its use can be used for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. A dual-blade device can be used for cutting the trabecular meshwork (“TM”) in the eye. The device tip provides entry into the Schlemm's canal via its size (i.e., for example, 0.2-0.3 mm width) and configuration where a ramp elevates the TM away from the outer wall of the Schlemm's canal and guides the TM to first and second lateral elements for creating first and second incisions through the TM. The dimensions and configuration of the blade is such that an entire strip of TM is removed without leaving TM leaflets behind and without causing collateral damage to adjacent tissues.

公开(公告)号：US20160331519A1

公开(公告)日：2016-11-17

申请号：US15218658

申请日：2016-07-25

Applicant: ClarVista Medical, Inc. ,  The Regents of the University of Colorado, a body corporate

Inventor： Malik Y. KAHOOK ,  Glenn SUSSMAN ,  Paul McLEAN ,  Andrew SCHIEBER

IPC: A61F2/16

CPC classification number: A61F2/1648 ,  A61F2/1613 ,  A61F2/1664 ,  A61F2/167 ,  A61F2/1672 ,  A61F2/1678 ,  A61F2002/1689 ,  A61F2002/169 ,  A61F2002/16902 ,  A61F2002/16905 ,  A61F2250/0067 ,  A61F2310/0097

Abstract: Modular IOL systems including a base and a lens, wherein the lens includes fixed and actuatable tabs for connection to the base. The modular IOL allows for the lens to be adjusted or exchanged while leaving the base in place, either intra-operatively or post-operatively. Drug delivery capabilities and/or sensing capabilities may be incorporated into the base. Injector devices may be used to facilitate placement of the base and the lens sequentially or simultaneously into the eye.

Abstract translation: 包括底座和透镜的模块化IOL系统，其中透镜包括用于连接到基座的固定和可启动的突出部。 模块化IOL允许调整或更换镜片，同时将基座放置在手术或手术后的位置。 药物递送能力和/或感测能力可以并入到基础中。 可以使用注射器装置以便于将基底和透镜顺序地或同时地放置到眼睛中。

公开(公告)号：US20250152334A1

公开(公告)日：2025-05-15

申请号：US19025447

申请日：2025-01-16

Applicant: Alcon Inc. ,  The Regents of the University of Colorado, a body corporate

Inventor： Malik Y. KAHOOK ,  Glenn SUSSMAN ,  Rudolph F. Zacher ,  Paul J. McLean ,  Robert E. ATKINSON

IPC: A61F2/16

Abstract: Intraocular lenses (IOLs) that improve lens stability by, for example, increasing anterior-posterior stiffness of the IOL, increasing anterior-posterior dimensions of the IOL and/or increasing contact area with the equator of the bag to resist movement of the IOL as the bag collapses over time. These IOLs may be non-modular (single component) or modular (multiple component). In modular embodiments, the IOL system may include intraocular base and optic components, which, when combined, form a modular IOL.

公开(公告)号：US20240148555A1

公开(公告)日：2024-05-09

申请号：US18409312

申请日：2024-01-10

Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE

Inventor： Malik Y. KAHOOK

IPC: A61F9/013 ,  A61B17/3209 ,  A61F9/007

CPC classification number: A61F9/0133 ,  A61B17/3209 ,  A61F9/00736 ,  A61F9/00781

Abstract: A microsurgical device and methods of its use can be used for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. A device can be used for cutting the trabecular meshwork (“TM”) in the eye. The device tip provides entry into the Schlemm's canal via its size (i.e., for example, 0.2-0.3 mm width) and configuration where a ramp elevates the TM away from the outer wall of the Schlemm's canal and guides the TM to first and second lateral elements for creating first and second incisions through the TM. The dimensions and configuration of the device is such that an entire strip of TM is removed without leaving TM leaflets behind and without causing collateral damage to adjacent tissues.

公开(公告)号：US20230404808A1

公开(公告)日：2023-12-21

申请号：US18237684

申请日：2023-08-24

Applicant: The Regents of the University of Colorado, a body corporate ,  New World Medical, Inc.

Inventor： Malik Y. KAHOOK ,  Khalid MANSOUR ,  Suhail ABDULLAH ,  Eric PORTEOUS ,  Vijay R. BALAN

IPC: A61F9/013 ,  A61F9/007 ,  A61B17/32

CPC classification number: A61F9/0133 ,  A61F9/00781 ,  A61B17/320068 ,  A61F9/00745 ,  A61B2017/00867

Abstract: The present invention relates to an ophthalmic knife and methods of its use for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. The device is configured for cutting the tissues within the eye, for example, a trabecular meshwork (TM).

公开(公告)号：US20230091994A1

公开(公告)日：2023-03-23

申请号：US18070218

申请日：2022-11-28

Applicant: The Regents of the University of Colorado, a body corporate ,  New World Medical, Inc.

Inventor： Malik Y. KAHOOK ,  Khalid MANSOUR ,  Suhail ABDULLAH ,  Eric PORTEOUS ,  Vijay R. BALAN

IPC: A61F9/013 ,  A61F9/007 ,  A61B17/32

Abstract: The present invention relates to an ophthalmic knife and methods of its use for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. The device is configured for cutting the tissues within the eye, for example, a trabecular meshwork (TM).