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21.发明申请Proton-conductive composite electrolyte membrane and producing method thereof 审中-公开质子导电复合电解质膜及其制备方法公开(公告)号：US20080213646A1
公开(公告)日：2008-09-04
申请号：US12081551
申请日：2008-04-17
IPC分类号： H01M8/10
CPC分类号： H01M8/1023 , B01D67/0079 , B01D67/0088 , B01D67/0093 , B01D69/02 , B01D69/10 , B01D69/141 , B29C67/20 , H01M8/106 , H01M8/1067 , H01M8/1081 , H01M2300/0082 , H01M2300/0091 , Y02P70/56 , Y10T428/249953
摘要： A composite electrolyte membrane of the present invention includes a porous body composed of an inorganic substance and an electrolyte material. The porous body includes therein plural spherical pores in which a diameter is substantially equal, and communicating ports each allowing the spherical pores adjacent to each other to communicate with each other. The electrolyte material is provided on the spherical pores and the communicating ports, has proton conductivity, and is composed of a hydrocarbon polymer. The proton-conductive composite electrolyte membrane has excellent ion conductivity, high heat resistance, and restricted swelling when being hydrous, and is capable of being produced at low cost.
摘要翻译： 本发明的复合电解质膜包括由无机物质和电解质材料构成的多孔体。 多孔体中具有直径大致相等的多个球形孔，并且各自允许彼此相邻的球形孔彼此连通的连通口。 电解质材料设置在球形孔和连通孔上，具有质子传导性，由烃类聚合物构成。 质子传导复合电解质膜具有优异的离子传导性，高耐热性，并且在含水时具有有限的溶胀，并能够以低成本制造。
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公开(公告)号：US20060173401A1
公开(公告)日：2006-08-03
申请号：US11195364
申请日：2005-08-02
申请人： Akihiko Tanioka , Mie Minagawa , Kiyoshi Kanamura , Akihiko Matsumura , Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama
发明人： Akihiko Tanioka , Mie Minagawa , Kiyoshi Kanamura , Akihiko Matsumura , Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama
IPC分类号： A61N1/30
CPC分类号： A61N1/044 , A61N1/0436 , A61N1/0444
摘要： The present invention provides an iontophoresis device with high administration efficient of a drug. An iontophoresis device, including an active electrode structure including: an electrode to which a positive electrical potential is applied; a drug holding part for holding a drug solution containing positively charged drug ions, the drug holding part being placed on a front side of the electrode; a cellulose-based resin film placed on a front side of the drug holding part or a complex film composed of a cation exchange membrane and a cellulose-based resin film placed on a front side of the cation exchange membrane, the complex film being placed on a front side of the drug holding part, in which the drug ions are administered through the cellulose-based resin film.
摘要翻译： 本发明提供了具有药物高效给药的离子电渗疗法装置。 一种离子电渗疗法装置，包括有源电极结构，包括：施加正电位的电极; 用于保持含有带正电荷的药物离子的药液的药物保持部，药物保持部位于电极的前侧; 将放置在药物保持部的前侧的纤维素系树脂膜或配置在阳离子交换膜前侧的阳离子交换膜和纤维素系树脂膜构成的复合膜，将复合膜置于 药物保持部的前侧，其中通过纤维素系树脂膜施用药物离子。
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公开(公告)号：US09017868B2
公开(公告)日：2015-04-28
申请号：US13151844
申请日：2011-06-02
CPC分类号： H01M4/8864 , H01M4/0404 , H01M4/0411 , H01M4/8828 , Y02E60/122 , Y02E60/50 , Y02P70/54 , Y10T29/49002 , Y10T29/49108 , Y10T29/49115
摘要： A negative-electrode active material layer formed between a negative-electrode current collector and a solid electrolyte layer has a line-and-space structure in which a plurality of stripe-shaped pattern elements extending in a Y direction are arranged while being separated from each other. A gradient at each contact point where the stripe-shaped pattern element, the negative-electrode current collector and the solid electrolyte layer are in contact with each other is made smaller than 90°.
摘要翻译： 形成在负极集电体和固体电解质层之间的负极活性物质层具有线状空间结构，其中沿着Y方向延伸的多个条状图案元素被排列成与每个 其他。 条状图案元件，负极集电体和固体电解质层彼此接触的各接触点的梯度小于90°。
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公开(公告)号：US08386030B2
公开(公告)日：2013-02-26
申请号：US11501672
申请日：2006-08-08
申请人： Kiyoshi Kanamura , Nobuharu Kosiba , Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama , Akihiko Matsumura
发明人： Kiyoshi Kanamura , Nobuharu Kosiba , Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama , Akihiko Matsumura
CPC分类号： A61N1/0436 , A61N1/044 , A61N1/0444 , A61N1/0448
摘要： An iontophoresis device including an active electrode assembly or a counter electrode assembly with a polarizable electrode containing any one of a conductive material having a capacitance per unit weight of 1 F/g or greater, a conductive material having a specific surface area of 10 m2/g or greater, and activated carbon is disclosed. The generation of gas or ions due to an electrode reaction occurring in an electrode assembly may be reduced or prevented. In addition, the alteration of an active agent due to a chemical reaction upon energization may be reduced or prevented.
摘要翻译： 1.一种离子电渗疗法装置，其特征在于，包括具有可极化电极的活性电极组件或对电极组件，所述可极化电极含有每单位重量的电容为1F / g以上的导电材料，比表面积为10m 2 / g以上，并且公开了活性炭。 可以减少或防止由于在电极组件中发生电极反应而产生气体或离子。 此外，可以减少或防止由于通电时的化学反应引起的活性剂的改变。
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公开(公告)号：US08295922B2
公开(公告)日：2012-10-23
申请号：US11501176
申请日：2006-08-07
CPC分类号： A61N1/0448 , A61N1/0436 , A61N1/0444
摘要： An iontophoresis device may be capable of preventing or reducing the generation of gas, or the production of undesirable ions, due to an electrode reaction occurring in an electrode assembly; or the alteration of an active agent due to a chemical reaction upon energization. A doping layer made of a substance such as a conductive polymer that effects an electrochemical reaction due to the doping or de-doping of an ion, may be formed in an electrode in an active electrode assembly or counter electrode assembly of an iontophoresis device.
摘要翻译： 离子电渗装置可以由于在电极组件中发生电极反应而能够防止或减少气体的产生或不需要的离子的产生; 或由于通电时的化学反应引起的活性剂的改变。 可以在离子电渗装置的有源电极组件或对电极组件中的电极中形成由诸如导电聚合物的物质制成的掺杂层，其由于离子的掺杂或去掺杂而实现电化学反应。
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26.发明申请公开(公告)号：US20120058416A1
公开(公告)日：2012-03-08
申请号：US13292679
申请日：2011-11-09
CPC分类号： H01M8/1023 , B01D67/0079 , B01D67/0088 , B01D67/0093 , B01D69/02 , B01D69/10 , B01D69/141 , B29C67/20 , H01M8/106 , H01M8/1067 , H01M8/1081 , H01M2300/0082 , H01M2300/0091 , Y02P70/56 , Y10T428/249953
摘要： A composite electrolyte membrane of the present invention includes a porous body composed of an inorganic substance and an electrolyte material. The porous body includes therein plural spherical pores in which a diameter is substantially equal, and communicating ports each allowing the spherical pores adjacent to each other to communicate with each other. The electrolyte material is provided on the spherical pores and the communicating ports, has proton conductivity, and is composed of a hydrocarbon polymer. The proton-conductive composite electrolyte membrane has excellent ion conductivity, high heat resistance, and restricted swelling when being hydrous, and is capable of being produced at low cost.
摘要翻译： 本发明的复合电解质膜包括由无机物质和电解质材料构成的多孔体。 多孔体中具有直径大致相等的多个球形孔，并且各自允许彼此相邻的球形孔彼此连通的连通口。 电解质材料设置在球形孔和连通孔上，具有质子传导性，由烃类聚合物构成。 质子传导复合电解质膜具有优异的离子传导性，高耐热性，并且在含水时具有有限的溶胀，并能够以低成本制造。
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公开(公告)号：US20090301882A1
公开(公告)日：2009-12-10
申请号：US11917497
申请日：2006-08-01
IPC分类号： C02F1/469
CPC分类号： A61N1/0448 , A61N1/0436 , A61N1/0444
摘要： An iontophoresis device may include an electrolyte solution holding portion and a drug solution holding portion. The electrolyte solution holding portion holds a solution of an electrolyte that dissociates into a first electrolytic ion of a first polarity type and a second electrolytic ion of a second polarity type in a solution. The drug solution holding portion holds a solution of a drug that dissociates into a drug ion of the first polarity type and a drug counter ion of the second polarity type. The iontophoresis device may also include a first ion exchange membrane with an ion exchange group of the first polarity type and a second ion exchange membrane with an ion exchange group of the second polarity type. The first and the second ion exchange members interpose the electrolyte solution holding portion and the drug solution holding portion.
摘要翻译： 离子电渗装置可以包括电解液保持部和药液保持部。 电解质溶液保持部分保持溶液中解离成第一极性类型的第一电解离子和第二极性类型的第二电解离子的电解质溶液。 药液保持部保持解离成第一极性药物离子的药物溶液和第二极性型药物抗衡离子。 离子电渗装置还可以包括具有第一极性类型的离子交换基团的第一离子交换膜和具有第二极性类型的离子交换基团的第二离子交换膜。 第一和第二离子交换构件插入电解液保持部和药液保持部。
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公开(公告)号：US07398121B2
公开(公告)日：2008-07-08
申请号：US10488970
申请日：2002-05-15
IPC分类号： A61N1/30
CPC分类号： A61N1/303 , A61N1/0444
摘要： An iontophoresis device useful for administering an ionic drug by iontophoresis has an iontophoresis electrode section (active electrode section) and a ground electrode section (inactive electrode section) both of which are to be connected to a power source. The iontophoresis device includes elements (members) of both of the electrode sections are all formed of membrane bodies, and includes ion exchange membranes different in ion selectivity, one being selective to ions of the same species as charged ions of the ionic drug and the other to ions different in species from the charged ions of the ionic drug that are arranged in the iontophoresis electrode section, and at least an ion exchange membrane selective to ions opposite to the charged ions of the ionic drug is arranged in the ground electrode section. The iontophoresis device can administer the ionic drug stably over a long period of time at high transport efficiency.
摘要翻译： 用于通过离子电渗法施用离子药物的离子电渗疗装置具有两个要连接到电源的离子电渗电极部分（有源电极部分）和接地电极部分（无电极部分）。 离子电渗装置包括两个电极部分的元件（构件）均由膜体形成，并且包括离子选择性不同的离子交换膜，一个对离子与离子药物的带电离子相同的离子的离子选择性 与离子电泳电极部中配置的离子性药物的带电离子不同的离子，并且至少对离子药物的与带电离子相反的离子选择性的离子交换膜配置在接地电极部。 离子电渗装置可以在高运输效率下长时间稳定地施用离子药物。
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公开(公告)号：US20070112294A1
公开(公告)日：2007-05-17
申请号：US11522496
申请日：2006-09-14
IPC分类号： A61N1/30
CPC分类号： A61N1/30
摘要： An iontophoresis device may be capable of preventing the generation of gas or ions upon energization, and/or may be capable of preventing the alteration of active agent ions due to an electrode reaction. Energization from an electrode to an active agent reservoir may be performed through an ionic liquid. The ionic liquid may include an anion such as PF6-, BF4-, AlCl4-, ClO4-, a hydrogen sulfate ion, bis-trifluoro-alkyl-sulfonyl-imide, or trifluoro-methane-sulfonate, and a cation such as an imidazolium derivative, a pyridinium derivative, a piperidinium derivative, a pyrolidinium derivative, and a tetra-alkyl-ammonium derivative.
摘要翻译： 离子电渗装置可能能够防止在通电时产生气体或离子，和/或可以防止由于电极反应而引起的活性剂离子的改变。 从电极到活性剂储存器的通电可以通过离子液体进行。 离子液体可以包括阴离子如PF6-，BF4-，AlCl4-，ClO4-，硫酸氢根离子，双 - 三氟 - 烷基 - 磺酰基 - 酰亚胺或三氟 - 甲烷磺酸盐，和阳离子如咪唑鎓 衍生物，吡啶鎓衍生物，哌啶鎓衍生物，吡咯烷鎓衍生物和四烷基铵衍生物。
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公开(公告)号：US20070060860A1
公开(公告)日：2007-03-15
申请号：US11506598
申请日：2006-08-18
IPC分类号： A61N1/30
CPC分类号： A61N1/0444 , A61N1/0448
摘要： One or more electrodes of an iontophoresis device may include a composite ion exchange membrane comprising a first ion exchange membrane of a first polarity and a second ion exchange membrane of a second polarity, or a first ion exchange membrane of the first polarity, a semi-permeable membrane, and a second ion exchange membrane of the second polarity. The respective membranes may be integrally coupled together. This may lead to simplified production processes, automated production, mass production, and reductions in production costs for the iontophoresis device.
摘要翻译： 离子电渗装置的一个或多个电极可以包括复合离子交换膜，其包括第一极性的第一离子交换膜和第二极性的第二离子交换膜，或第一极性的第一离子交换膜， 和第二极性的第二离子交换膜。 各个膜可以整体耦合在一起。 这可能导致简化的生产过程，自动化生产，批量生产以及降低离子电渗装置的生产成本。
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