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    FUNCTIONAL SOFT MATERIALS AND METHODS OF MAKING AND USING THEREOF
    21.
    发明申请
    FUNCTIONAL SOFT MATERIALS AND METHODS OF MAKING AND USING THEREOF 有权

    公开(公告)号：US20250164324A1

    公开(公告)日：2025-05-22

    申请号：US19022634

    申请日：2025-01-15

    Applicant: UNIVERSITY OF KANSAS

    Inventor： Cory BERKLAND ,  Jonathan WHITLOW ,  Jean SALASH

    IPC: G01L1/12 ,  B29C64/118 ,  B29K83/00 ,  B29K105/16 ,  B29K509/08 ,  B33Y10/00 ,  B33Y70/00 ,  B33Y80/00 ,  C09D11/037 ,  C09D11/102 ,  H01F1/032 ,  H01F7/20

    Abstract: Disclosed are functional materials for use in additive manufacturing (AM). The functional material can comprise an elastomeric composition (e.g., a silicone composite) for use in, for example, direct ink writing. The elastomeric composition can include and elastomeric resin, and a magnetic nanorod filler dispersed within the elastomeric resin. Nanorod characteristics (e.g., length, diameter, aspect ratio) can be selected to create 3D-printed constructs with desired mechanical properties along different axes. Furthermore, since nickel nanorods are ferromagnetic, the spatial distribution and orientation of nanorods within the continuous phase can be controlled with an external magnetic field. This level of control over the nanostructure of the material system offers another degree of freedom in the design of functional parts and components with anisotropic properties. Magnetic fields can be used to remotely sense compression of the constructs, or alternatively, control the stiffness of these.

    SMALL-PARTICLE SIZE POLYMERIC CHELATORS
    23.
    发明申请
    SMALL-PARTICLE SIZE POLYMERIC CHELATORS 有权

    公开(公告)号：US20240368356A1

    公开(公告)日：2024-11-07

    申请号：US18683230

    申请日：2022-08-12

    Applicant: THE UNIVERSITY OF KANSAS

    Inventor： Cory BERKLAND ,  Jian QIAN

    IPC: C08J3/12 ,  C08F8/00 ,  C08J3/075 ,  C08J3/24

    Abstract: Compositions and methods for making a composition comprising a plurality of polymeric chelator particles comprising a plurality of cross-linked polyamine polymer backbone chains and one or more chelators covalently coupled thereto, wherein at least 90% of the plurality of the polymeric chelator particles have a particle size of 300 μm or less. Also disclosed are methods of using the composition, e.g., for removing metal from a medium or treating iron overload disease.

    MAGNETIC SENSORS AND METHODS OF MAKING AND USING THEREOF
    24.
    发明公开
    MAGNETIC SENSORS AND METHODS OF MAKING AND USING THEREOF 审中-公开

    公开(公告)号：US20240272018A1

    公开(公告)日：2024-08-15

    申请号：US18565719

    申请日：2022-05-31

    Applicant: UNIVERSITY OF KANSAS

    Inventor： Cory BERKLAND ,  Jonathan MILLER

    IPC: G01L1/12 ,  A61B5/05 ,  H01F7/08

    CPC classification number: G01L1/122 ,  A61B5/05 ,  H01F7/081 ,  A61B2562/0223

    Abstract: Described herein are magnetic sensors (e.g., force sensors) as well as methods of making and using thereof The magnetic sensors can employ a soft magnetic composite (e.g a composite comprising a population of magnetic particles dispersed within an elastomeric resin) paired with a magnetometer. These sensors can overcome many of the traditional shortcomings that have hampered the effectiveness of existing compression sensors in certain applications, including large size, a lack of 3-dimensional sensing capacity, need for sensors to incorporate rigid components, and/or signal quality issues associated with the orientation or deformation of soft composites under compression.

    HYDROGEL PRECURSORS HAVING NANOPARTICLES
    26.
    发明申请
    HYDROGEL PRECURSORS HAVING NANOPARTICLES 审中-公开

    公开(公告)号：US20190314554A1

    公开(公告)日：2019-10-17

    申请号：US16428534

    申请日：2019-05-31

    Applicant: THE UNIVERSITY OF KANSAS

    Inventor： Michael DETAMORE ,  Emily BECK ,  Stevin GEHRKE ,  Cory BERKLAND

    IPC: A61L27/48 ,  A61L27/38 ,  A61L27/50 ,  A61L27/20 ,  A61L27/52 ,  A61L27/54

    Abstract: An implantable hydrogel precursor composition can include: a cross-linkable polymer matrix that is biocompatible; and a plurality of polymer particles in the cross-linkable polymer matrix. The cross-linkable polymer matrix can include a cross-linkable hyaluronic acid polymer that has cross-linkable functional groups. The hyaluronic acid polymer can be a methacrylated hyaluronic acid polymer. The methacrylated hyaluronic acid polymer can have a molecular weight from about 500 kDa to about 1.8 MDa. The polymer particles can include a cross-linked hyaluronic acid. The cross-linkable polymer matrix having the polymer particles has a yield stress. The cross-linkable polymer matrix having the polymer particles has shape retention at physiological temperatures. The composition can include live cells in the cross-linkable polymer matrix. The composition can include a biologically active agent in the cross-linkable polymer matrix.

    FUNCTIONAL SOFT MATERIALS AND METHODS OF MAKING AND USING THEREOF
    28.
    发明申请
    FUNCTIONAL SOFT MATERIALS AND METHODS OF MAKING AND USING THEREOF 有权

    公开(公告)号：US20240402023A1

    公开(公告)日：2024-12-05

    申请号：US18601260

    申请日：2024-03-11

    Applicant: UNIVERSITY OF KANSAS

    Inventor： Cory BERKLAND ,  Jonathan WHITLOW ,  Jean SALASH

    IPC: G01L1/12 ,  B29C64/118 ,  B29K83/00 ,  B29K105/16 ,  B29K509/08 ,  B33Y10/00 ,  B33Y70/00 ,  B33Y80/00 ,  C09D11/037 ,  C09D11/102 ,  H01F1/032 ,  H01F7/20

    Abstract: Disclosed are functional materials for use in additive manufacturing (AM). The functional material can comprise an elastomeric composition (e.g., a silicone composite) for use in, for example, direct ink writing. The elastomeric composition can include and elastomeric resin, and a magnetic nanorod filler dispersed within the elastomeric resin. Nanorod characteristics (e.g., length, diameter, aspect ratio) can be selected to create 3D-printed constructs with desired mechanical properties along different axes. Furthermore, since nickel nanorods are ferromagnetic, the spatial distribution and orientation of nanorods within the continuous phase can be controlled with an external magnetic field. This level of control over the nanostructure of the material system offers another degree of freedom in the design of functional parts and components with anisotropic properties. Magnetic fields can be used to remotely sense compression of the constructs, or alternatively, control the stiffness of these.

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