公开(公告)号：US20060200325A1

公开(公告)日：2006-09-07

申请号：US11331219

申请日：2006-01-13

申请人： Yoshiharu Hayashi

发明人： Yoshiharu Hayashi

IPC分类号： G06F17/10

CPC分类号： F22B35/18 ,  Y02E20/16

摘要： A method for configuring the physical model of a heat recovery steam generator that can estimate the state quantity of generated steam from the state quantity of the exhaust gas to be introduced, and capable of establishing the physical model of a combined cycle power generation facility thereby. The optimum values for the flow rates Flp and Fhp, pressures and temperatures Tlp and Thp of the low pressure main steam and high pressure main steam are computed in such a way as to ensure that an objective function E stored in advance will come close to zero.

摘要翻译： 一种用于配置热回收蒸汽发生器的物理模型的方法，所述热回收蒸汽发生器可以从待引入的排气的状态量估计产生的蒸汽的状态量，并且能够建立由此产生的联合循环发电设备的物理模型。 计算低压主蒸汽和高压主蒸汽的流量Flp和Fhp，压力和温度Tlp和Thp的最佳值，以确保预先存储的目标函数E将接近零 。

公开(公告)号：US20060148875A1

公开(公告)日：2006-07-06

申请号：US11363202

申请日：2006-02-28

申请人： Yoshiharu Hayashi ,  Nobuharu Goto

发明人： Yoshiharu Hayashi ,  Nobuharu Goto

IPC分类号： A61K31/4164

CPC分类号： C07D233/54 ,  A61K31/4164 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： The present invention relates to an agent for the prophylaxis and treatment of diabetic complications comprising, as an active ingredient, 4-[α-hydroxy-2-methyl-5-(1-imidazolyl)benzyl]-3,5-dimethylbenzoic acid, an optically active compound thereof or a pharmaceutically acceptable salt thereof. The present invention further relates to a method for the prophylaxis and treatment of diabetic complications comprising administering an effective amount of this compound. The medicament of the present invention is useful for the prophylaxis and treatment of diabetic complications, namely, diabetic neuropathy, nephropathy, ophthalmopathy, arteriosclerosis and the like. The action of the drug is long-lasting for very small doses and a single administration a day is sufficient.

摘要翻译： 本发明涉及用于预防和治疗糖尿病并发症的药剂，其包含作为活性成分的4- [α-羟基-2-甲基-5-（1-咪唑基）苄基] -3,5-二甲基苯甲酸， 其光学活性化合物或其药学上可接受的盐。 本发明还涉及预防和治疗糖尿病并发症的方法，包括给予有效量的该化合物。 本发明的药物可用于预防和治疗糖尿病并发症，即糖尿病性神经病，肾病，眼病，动脉硬化等。 药物的作用对于非常小的剂量是持久的，每天一次给药是足够的。

公开(公告)号：US4708734A

公开(公告)日：1987-11-24

申请号：US807799

申请日：1985-12-11

申请人： Yoshiharu Hayashi ,  Teruyuki Misumi

发明人： Yoshiharu Hayashi ,  Teruyuki Misumi

IPC分类号： C07C45/71 ,  C07C49/84 ,  C07C59/90 ,  C07C205/38 ,  C07C205/45 ,  C07C251/54 ,  C07C327/22 ,  A01N37/00 ,  C07C79/46 ,  C07C81/08 ,  C07C101/00

CPC分类号： C07C327/22 ,  C07C205/38 ,  C07C205/45 ,  C07C251/54 ,  C07C45/71 ,  C07C49/84 ,  C07C59/90

摘要： 5-2-chloro-4-trifluoromethylphenoxy)-2-nitro-.alpha.-substituted-acetophenones and oxime derivatives thereof represented by the formula ##STR1## wherein R.sup.1 and Y are as defined in the disclosure, process for the preparation thereof, herbicidal composition and method for the destruction of undesirable weeds. The herbicides comprising the above compounds are capable of selectively controlling undesirable weeds among desirable crop plants.

摘要翻译： 5-2-氯-4-三氟甲基苯氧基）-2-硝基-α-取代的 - 苯乙酮及其由式（I）表示的肟衍生物，其中R 1和Y如本公开所定义，其制备方法 ，除草组合物和破坏不需要的杂草的方法。 包含上述化合物的除草剂能够选择性地控制期望的作物植物中不期望的杂草。

公开(公告)号：US08534236B2

公开(公告)日：2013-09-17

申请号：US12893711

申请日：2010-09-29

申请人： Masayuki Taniguchi ,  Tsuyoshi Shibata ,  Yoshiharu Hayashi

发明人： Masayuki Taniguchi ,  Tsuyoshi Shibata ,  Yoshiharu Hayashi

IPC分类号： F23B80/02

CPC分类号： F23C9/003 ,  F23C2202/10 ,  F23C2900/06041 ,  F23J2215/50 ,  F23L7/007 ,  F23L2900/07001 ,  F23L2900/07005 ,  F23L2900/07006 ,  F25J3/04533 ,  F25J2215/02 ,  F25J2245/40 ,  F25J2245/42 ,  F25J2260/80 ,  Y02E20/322 ,  Y02E20/344

摘要： An oxyfuel combustion boiler plant comprising: a boiler having an air separation unit for manufacturing oxygen by separating nitrogen from air, a burner for burning the oxygen supplied from the air separation unit and pulverized coal, and a primary system pipe for supplying the pulverized coal to the burner, exhaust gas recirculation system pipe for supplying combustion exhaust gas discharged from the boiler to the primary system pipe, a carbon dioxide capture unit for capturing carbon dioxide in the exhaust gas discharged from the boiler, the oxyfuel combustion boiler plant is further comprising: an oxygen buffer tank disposed on a downstream side of the air separation unit; an oxygen supply pipe for supplying oxygen to the primary system pipe of the burner from the oxygen buffer tank; and a nitrogen supply pipe for supplying a part of nitrogen generated from the air separation unit or an air supply pipe for supplying air from outside which is connected to the oxygen supply pipe on a downstream side of the oxygen buffer tank and on an upstream side of a junction of the primary system pipe.

摘要翻译： 一种氧燃烧锅炉设备，包括：锅炉，具有用于通过从空气中分离氮气来制造氧气的空气分离单元，用于燃烧从空气分离单元和粉煤供应的氧气的燃烧器，以及用于将粉煤供应到主体系统管 所述燃烧器，用于从所述锅炉向所述主系统管排出的燃烧废气的排气再循环系统管，用于捕获从所述锅炉排出的废气中的二氧化碳的二氧化碳捕获单元，所述氧燃料燃烧锅炉设备还包括： 设置在所述空气分离单元的下游侧的氧缓冲罐; 用于从氧气缓冲罐向燃烧器的主系统管供氧的供氧管; 以及氮气供给管，其用于供给来自所述空气分离单元的氮气的一部分或用于从外部供给空气的空气供给管，所述空气供给管与所述氧气缓冲罐的下游侧的氧供给管连接，并且在所述供气管的上游侧 主系统管道的接头。

公开(公告)号：US20120324893A1

公开(公告)日：2012-12-27

申请号：US13578642

申请日：2011-02-07

申请人： Yoshiharu Hayashi

发明人： Yoshiharu Hayashi

IPC分类号： F01K11/02 ,  F01K9/00 ,  F01K7/34

CPC分类号： F01K7/40 ,  F01K7/34 ,  F01K13/02 ,  F22D1/003 ,  F22D1/02 ,  F22D1/12 ,  F22D1/32 ,  F22D1/325 ,  F22D1/40 ,  F23J15/06 ,  Y02E20/363

摘要： A coal-fired power plant having a control unit including a first flow rate control valve for regulating a water flow rate of a water feed bypass system, a second flow rate control valve installed in an extraction pipe for extracting steam from a steam turbine, a first temperature sensor on a downstream side of a heat recovery device, and a second temperature sensor on a downstream side of a heat exchanger and the control unit regulates opening of the first and second flow rate control valves on the basis of an exhaust gas temperature detected by the first temperature sensor and a feed water temperature detected by the second temperature sensor.Accordingly, even when a recovery heat quantity of the heat recovery device installed on a gas duct is changed due to deterioration with age of a boiler, a reduction in plant reliability and plant efficiency can be suppressed.

摘要翻译： 一种燃煤发电厂，具有控制单元，该控制单元包括用于调节给水旁路系统的水流量的第一流量控制阀，安装在从蒸汽轮机抽取蒸汽的抽取管中的第二流量控制阀， 在热回收装置的下游侧的第一温度传感器和热交换器的下游侧的第二温度传感器，并且控制单元基于检测到的废气温度来调节第一和第二流量控制阀的打开 由第一温度传感器和由第二温度传感器检测的给水温度。 因此，即使当由于锅炉的老化而劣化而改变安装在气体导管上的热回收装置的回收热量时，也可以抑制工厂可靠性和设备效率的降低。

公开(公告)号：US20110094105A1

公开(公告)日：2011-04-28

申请号：US12908551

申请日：2010-10-20

申请人： Tetsuma TATSUMI ,  Masayuki Taniguchi ,  Tsuyoshi Shibata ,  Yoshiharu Hayashi

发明人： Tetsuma TATSUMI ,  Masayuki Taniguchi ,  Tsuyoshi Shibata ,  Yoshiharu Hayashi

IPC分类号： B21D51/24

CPC分类号： F23L7/007 ,  F23C9/003 ,  F23C2202/30 ,  F23L2900/07001 ,  Y02E20/322 ,  Y02E20/344 ,  Y10T29/49352 ,  Y10T29/49387 ,  Y10T29/49716

摘要： A method for retrofitting a pulverized coal boiler in an air combustion boiler system is disclosed, which has a plurality of burners over a plurality of stages along the vertical direction on a wall surface of a furnace of the pulverized coal boiler and an after-air port for introducing air for two-stage combustion located above the burners to retrofit into a two-stage combustion pulverized coal boiler in an oxyfuel combustion boiler system.

摘要翻译： 公开了一种在空气燃烧锅炉系统中改造粉煤锅炉的方法，该方法在粉煤锅炉的炉壁的表面上沿着垂直方向在多个级上具有多个燃烧器，以及后空气口 用于引入位于燃烧器上方的用于两级燃烧的空气，以改造为在氧燃烧锅炉系统中的两级燃烧粉煤锅炉。

公开(公告)号：US20070203669A1

公开(公告)日：2007-08-30

申请号：US11710422

申请日：2007-02-26

申请人： Yoshiharu Hayashi

发明人： Yoshiharu Hayashi

IPC分类号： G06F17/40 ,  G06F17/00

CPC分类号： G05B23/0235 ,  Y02E20/16

摘要： A performance monitoring system for monitoring the performance of a single shaft combined cycle plant having a steam turbine, a gas turbine and a generator connected by a single shaft, comprising: a gas turbine calculation means 2 for estimating a gas turbine output and a gas turbine exhaust gas temperature from a process value related to the gas turbine; a steam turbine calculation means 3 for estimating a steam turbine output from a process value related to the steam turbine; and a performance monitoring calculation means 6 which, in the case where the difference between the total of the estimate values for the estimated steam turbine output and the estimated gas turbine output and the actual measurement of the generator output exceeds a prescribed value, if the difference between the estimate value of the gas turbine exhaust gas temperature and the actual measurement of the gas turbine exhaust gas temperature exceeds another prescribed value, determines gas turbine abnormality, while if the difference between the estimate value of the gas turbine exhaust gas temperature and the actual measurement of the gas turbine exhaust gas temperature does not exceed the another prescribed value, determines steam turbine abnormality.

摘要翻译： 一种用于监测具有蒸汽轮机，燃气轮机和通过单个轴连接的发电机的单轴联合循环设备的性能的性能监视系统，包括：用于估计燃气轮机输出的燃气轮机计算装置2和燃气轮机 来自与燃气轮机相关的过程值的废气温度; 蒸汽轮机计算装置3，用于根据与蒸汽轮机相关的过程值来估计蒸汽轮机的输出; 以及性能监视计算装置6，其中，在估计的蒸汽涡轮机输出的估计值和估计的燃气轮机的输出的总和与发电机的输出的实际测量之间的差异超过规定值的情况下，如果差值 在燃气轮机排气温度的估计值与燃气轮机废气温度的实际测量值之间超过另一规定值时，确定燃气轮机异常，而如果燃气轮机废气温度的估计值与实际 燃气轮机废气温度的测量不超过另一规定值，从而确定汽轮机异常。

公开(公告)号：US20060173056A1

公开(公告)日：2006-08-03

申请号：US11351118

申请日：2006-02-10

申请人： Hiroshi Kitajima ,  Hiroshi Sakashita ,  Fumihiko Akahoshi ,  Yoshiharu Hayashi

发明人： Hiroshi Kitajima ,  Hiroshi Sakashita ,  Fumihiko Akahoshi ,  Yoshiharu Hayashi

IPC分类号： A61K31/427 ,  A61K31/4025 ,  C07D417/02 ,  C07D403/02

CPC分类号： C07D401/14 ,  C07D207/16 ,  C07D403/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04 ,  C07D417/06 ,  C07D417/14 ,  C07D471/10 ,  C07D487/04

摘要： The present invention aims at providing compounds having therapeutic effects due to a DPP-IV inhibitory action, and satisfactory as pharmaceutical products. The present inventors have found that derivatives having a substituent introduced into the γ-position of proline represented by the formula (I) wherein each symbol is as defined in the specification, have a potent DPP-IV inhibitory activity, and completed the present invention by increasing the stability.

公开(公告)号：US20050245538A1

公开(公告)日：2005-11-03

申请号：US11142523

申请日：2005-06-02

申请人： Hiroshi Kitajima ,  Hiroshi Sakashita ,  Fumihiko Akahoshi ,  Yoshiharu Hayashi

发明人： Hiroshi Kitajima ,  Hiroshi Sakashita ,  Fumihiko Akahoshi ,  Yoshiharu Hayashi

IPC分类号： A61P1/02 ,  A61P3/04 ,  A61P3/10 ,  A61P13/08 ,  A61P17/00 ,  A61P31/18 ,  A61P35/04 ,  A61P37/06 ,  A61P43/00 ,  C07D207/16 ,  C07D401/14 ,  C07D403/14 ,  C07D413/14 ,  C07D417/06 ,  C07D417/14 ,  C07D471/10 ,  C07D487/04 ,  C07D498/04 ,  A61K31/496 ,  A61K31/427 ,  A61K31/454 ,  C07D417/02

CPC分类号： C07D401/14 ,  C07D207/16 ,  C07D403/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04 ,  C07D417/06 ,  C07D417/14 ,  C07D471/10 ,  C07D487/04

摘要： The present invention aims at providing compounds having therapeutic effects due to a DPP-IV inhibitory action, and satisfactory as pharmaceutical products. The present inventors have found that derivatives having a substituent introduced into the γ-position of proline represented by the formula (I) wherein each symbol is as defined in the specification, have a potent DPP-IV inhibitory activity, and completed the present invention by increasing the stability.

摘要翻译： 本发明旨在提供由于DPP-IV抑制作用而具有治疗作用的化合物，并且作为药物产品令人满意。 本发明人发现具有引入式（I）表示的脯氨酸的γ-位置的取代基的衍生物，其中每个符号如说明书中所定义，具有有效的DPP-IV抑制活性，并通过 增加稳定性。

公开(公告)号：US20050090531A1

公开(公告)日：2005-04-28

申请号：US10969885

申请日：2004-10-22

申请人： Masakazu Kawasaki ,  Nobuharu Gotoh ,  Yoshiharu Hayashi ,  Kazuyuki Kawasaki

发明人： Masakazu Kawasaki ,  Nobuharu Gotoh ,  Yoshiharu Hayashi ,  Kazuyuki Kawasaki

IPC分类号： A61K31/4164 ,  A61K31/4174 ,  A61K31/4439 ,  A61P25/28 ,  C07D521/00 ,  C07D43/02

CPC分类号： C07D249/08 ,  A61K31/4164 ,  A61K31/4174 ,  A61K31/4439 ,  C07D231/12 ,  C07D233/56

摘要： The MAG expression promoter of the present invention contains a compound of the formula (I) wherein each symbol is as defined in the specification, an optically active form thereof or a pharmaceutically acceptable salt thereof. As a compound of the formula (1), 4-[α-hydroxy-5-(1-imidazolyl)-2-methylbenzyl]-3,5-dimethylbenzoic acid is exemplified. The MAG expression promoter of the present invention is useful as an agent for the prophylaxis and/or treatment of a disease of mammals inclusive of humans, which mainly presents hypomyelination, further, dysmyelination or demyelination.

摘要翻译： 本发明的MAG表达启动子含有式（I）化合物，其中每个符号如说明书中所定义，其光学活性形式或其药学上可接受的盐。 作为式（1）的化合物，例举了4- [α-羟基-5-（1-咪唑基）-2-甲基苄基] -3,5-二甲基苯甲酸。 本发明的MAG表达启动子可用作预防和/或治疗包括人类在内的哺乳动物疾病的药剂，其主要表现为脱髓鞘，进一步发生脱髓鞘或脱髓鞘。