公开(公告)号：US20050233465A1

公开(公告)日：2005-10-20

申请号：US11107348

申请日：2005-04-14

Applicant: Scott Miller

Inventor： Scott Miller

IPC: C07D221/22 ,  C09B5/62 ,  G01N21/75 ,  G01N21/80

CPC classification number: B82Y30/00 ,  C09B5/62

Abstract: The present invention provides chemical compounds (compositions of matter) and methods useful for determining pH and/or pH change in an environment. Specific compounds of the invention include at least five fused molecular rings.

Abstract translation: 本发明提供化合物（物质组合物）和用于测定环境中pH和/或pH变化的方法。 本发明的具体化合物包括至少五个稠合的分子环。

公开(公告)号：US20050032204A1

公开(公告)日：2005-02-10

申请号：US10664067

申请日：2003-09-16

Applicant: Seth Rodgers ,  Andrey Zarur ,  A. Russo ,  Sean Leblanc ,  Xinyu Li ,  Howard Schreyer

Inventor： Seth Rodgers ,  Andrey Zarur ,  A. Russo ,  Sean Leblanc ,  Xinyu Li ,  Howard Schreyer

IPC: C12M1/34 ,  C12Q1/20

CPC classification number: B01L3/5027 ,  B01L2200/028 ,  B01L2300/0874 ,  B01L2300/0877 ,  B01L2300/0887 ,  B01L2400/046

Abstract: The present invention generally relates to chemical, biological, and/or biochemical reactor chips and other reaction systems such as microreactor systems, as well as systems and methods for constructing and using such devices. In one aspect, a chip or other reaction system may be constructed so as to promote cell growth within it. In certain embodiments, the chips or other reaction systems of the invention include one or more reaction sites. The reaction sites can be very small, for example, with a volume of less than about 1 ml. In one aspect of the invention, a chip is able to detect, measure and/or control an environmental factor such as the temperature, pressure, CO2 concentration, O2 concentration, relative humidity, pH, etc. associated with one or more reaction sites, by using one or more sensors, actuators, processors, and/or control systems. In another aspect, the present invention is directed to materials and systems having humidity and/or gas control, for example, for use with a chip. Such materials may have high oxygen permeability and/or low water vapor permeability. The present invention, in still another aspect, generally relates to light-interacting components suitable for use in chips and other reactor systems. These components may include waveguides, optical fibers, light sources, photodetectors, optical elements, and the like.

Abstract translation: 本发明一般涉及化学，生物和/或生化反应堆芯片和其他反应系统，例如微反应器系统，以及用于构建和使用这些装置的系统和方法。 在一个方面，可以构建芯片或其它反应系统，以促进细胞内的细胞生长。 在某些实施方案中，本发明的芯片或其它反应体系包括一个或多个反应位点。 反应位点可以非常小，例如，体积小于约1ml。 在本发明的一个方面，芯片能够检测，测量和/或控制与一个或多个反应位点相关联的环境因素例如温度，压力，CO 2浓度，O 2浓度，相对湿度，pH等， 通过使用一个或多个传感器，致动器，处理器和/或控制系统。 在另一方面，本发明涉及具有例如用于芯片的湿度和/或气体控制的材料和系统。 这样的材料可以具有高氧渗透性和/或低水蒸汽渗透性。 在另一方面，本发明通常涉及适用于芯片和其它反应器系统的光相互作用组分。 这些组件可以包括波导，光纤，光源，光电检测器，光学元件等。

公开(公告)号：US20040132166A1

公开(公告)日：2004-07-08

申请号：US10664046

申请日：2003-09-16

Applicant: BioProcessors Corp.

Inventor： Scott E. Miller ,  Gennady Malin ,  Howard B. Schreyer ,  Seth T. Rodgers ,  Andrey J. Zarur

IPC: C12M001/34

CPC classification number: C12M23/16 ,  B01L3/502707 ,  B01L7/00 ,  B01L2200/0689 ,  B01L2300/0816 ,  B01L2300/0874 ,  B01L2300/0883 ,  B01L2300/0887 ,  B01L2300/10 ,  B01L2300/1822 ,  B01L2300/1827

Abstract: The present invention generally relates to chemical, biological, and/or biochemical reactor chips and other reaction systems such as microreactor systems, as well as systems and methods for constructing and using such devices. In one aspect, a chip or other reaction system may be constructed so as to promote cell growth within it. In certain embodiments, the chips or other reaction systems of the invention include one or more reaction sites. The reaction sites can be very small, for example, with a volume of less than about 1 ml. In one aspect of the invention, a chip is able to detect, measure and/or control an environmental factor such as the temperature, pressure, CO2 concentration, O2 concentration, relative humidity, pH, etc. associated with one or more reaction sites, by using one or more sensors, actuators, processors, and/or control systems. In another aspect, the present invention is directed to materials and systems having humidity and/or gas control, for example, for use with a chip. Such materials may have high oxygen permeability and/or low water vapor permeability. The present invention, in still another aspect, generally relates to light-interacting components suitable for use in chips and other reactor systems. These components may include waveguides, optical fibers, light sources, photodetectors, optical elements, and the like.

Abstract translation: 本发明一般涉及化学，生物和/或生化反应堆芯片和其他反应系统，例如微反应器系统，以及用于构建和使用这些装置的系统和方法。 在一个方面，可以构建芯片或其它反应系统，以促进细胞内的细胞生长。 在某些实施方案中，本发明的芯片或其它反应体系包括一个或多个反应位点。 反应位点可以非常小，例如，体积小于约1ml。 在本发明的一个方面，芯片能够检测，测量和/或控制与一个或多个反应位点相关联的环境因素例如温度，压力，CO 2浓度，O 2浓度，相对湿度，pH等， 通过使用一个或多个传感器，致动器，处理器和/或控制系统。 在另一方面，本发明涉及具有例如用于芯片的湿度和/或气体控制的材料和系统。 这样的材料可以具有高氧渗透性和/或低水蒸汽渗透性。 在另一方面，本发明通常涉及适用于芯片和其它反应器系统的光相互作用组分。 这些组件可以包括波导，光纤，光源，光电检测器，光学元件等。