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公开(公告)号：US10076445B2
公开(公告)日：2018-09-18
申请号：US14412168
申请日：2013-03-14
CPC分类号： A61F9/00834 , A61F2/1662 , A61F9/0081 , A61F9/00831 , A61F9/0084 , A61F2009/00851 , A61F2009/0087 , A61F2009/00889
摘要： A system and method are provided for removing a natural lens and inserting an Intraocular Lens (IOL) into the lens capsule of an eye. Specifically, this is accomplished by inserting the IOL through an opening on the posterior capsule that is created using a focused laser beam. The system includes a laser unit, a detector for creating images of the interior of the eye, and a computer that controls the cooperative functions of the detector and the laser unit. Based on images of the posterior capsule provided by the detector, the computer is used to control movements of the focal point through tissue of the posterior capsule to perform Laser Induced Optical Breakdown (LIOB) on posterior capsule tissue. The result is a laser capsulotomy that creates an opening through the posterior capsule allowing the natural lens to be removed and the IOL to be implanted.
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22.发明申请公开(公告)号：US20180250163A1
公开(公告)日：2018-09-06
申请号：US15756553
申请日：2016-08-31
申请人： LUTRONIC VISION INC.
发明人： Hee Chul LEE
CPC分类号： A61F9/0084 , A61F9/008 , A61F9/00814 , A61F9/00821 , A61F9/009 , A61F2009/00851 , A61F2009/00863 , A61F2009/0087 , A61F2009/00872
摘要： An apparatus for ocular treatment according to the present invention comprises: a beam generation unit for generating a therapeutic beam; a beam transfer unit comprising a first lens part capable of forming an optical path through which the therapeutic beam oscillated from the beam generation unit travels in the ocular fundus, and of varying the focal length so that the beam is transferred in a predetermined spot size in the ocular fundus; and a control unit, connected to the beam transfer unit, for controlling the focal length of the therapeutic beam of the first lens part.
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公开(公告)号：US20180200112A1
公开(公告)日：2018-07-19
申请号：US15746415
申请日：2016-07-06
IPC分类号： A61F9/008
CPC分类号： A61F9/00834 , A61B3/1005 , A61B3/102 , A61B3/1025 , A61B3/14 , A61F9/00827 , A61F9/0084 , A61F2009/00844 , A61F2009/00851 , A61F2009/0087 , A61F2009/00887
摘要： Systems and methods for localizing intraocular lens and/or existing refractive index patterns, to laser write-patterns, and to refractive index patterns in order to modify the refractive index by application of femtosecond laser pulses. OCT-based confocal detection and sectional image systems are provided for localization purposes, the systems being particularly suitable for the detection of phase patterns in addition to the localization of the IOL. With respect to laser write-patterns, the modification of existing refractive index patterns in the IOL is carried out by destroying existing structures or supplementing existing refractive index patterns.
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公开(公告)号：US10010451B2
公开(公告)日：2018-07-03
申请号：US14460778
申请日：2014-08-15
申请人： NIDEK CO., LTD.
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00825 , A61F2009/00851 , A61F2009/0087 , A61F2009/00872 , A61F2009/00897
摘要： An ophthalmic laser surgical apparatus includes an XY scan unit, a light guiding optical element, an objective lens, and a Z scan unit. The XY scan unit includes a deflecting device for deflecting the pulsed laser beam, and scans the pulsed laser beam in a direction crossing an optical axis. The light guiding optical element is provided downstream of the deflecting device on the optical path of the pulsed laser beam. The light guiding optical element has refractive power, and guides the pulsed laser beam. The objective lens causes the pulsed laser beam through the XY scan unit and the light guiding optical element to converge in a tissue of a patient's eye. The Z scan unit varies the optical path length between the light guiding optical element and the objective lens while the objective lens is fixed in position on the optical path.
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公开(公告)号：US20180177630A1
公开(公告)日：2018-06-28
申请号：US15759409
申请日：2016-09-15
CPC分类号： A61F9/008 , A61B34/10 , A61B34/25 , A61B2034/107 , A61F2009/00851 , A61F2009/00878 , A61F2009/00887
摘要： A computer program product for controlling a laser-assisted eye treatment, configured to encode a system controller with a routine for planning the eye treatment, invention further relates to a laser-assisted eye treatment system including a laser treatment unit and a system controller, to a method for generating control data for a laser-assisted eye treatment system, to a planning method for a laser-assisted eye treatment and to an eye treatment method using a laser beam for treating a patient's eye. The invention provides systems and methods for a fast laser-assisted eye treatment of a patient's eye which improve the security and minimize the risk of a non-optimal eye treatment and enable sale eye treatment planning and a shortening of the critical phase of the eye treatment. Encoding a system controller by a routine for planning the eye treatment is strictly based on an anatomy of a patient's eye.
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公开(公告)号：US20170367878A9
公开(公告)日：2017-12-28
申请号：US14337843
申请日：2014-07-22
发明人： Michael KEMPE , Markus STREHLE , Dirk MUEHLHOFF , Mario GERLACH , Markus STICKER , Mark BISCHOFF , Manfred DICK , Michael BERGT
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00802 , A61F9/00804 , A61F9/00814 , A61F9/00825 , A61F9/00827 , A61F9/0084 , A61F2009/00844 , A61F2009/00851 , A61F2009/00865 , A61F2009/0087 , A61F2009/00872 , A61F2009/00874
摘要： The invention relates to a device for measuring an optical penetration that is triggered in a tissue underneath the tissue surface by means of therapeutic laser radiation which a laser-surgical device concentrates in a treatment focus located in said tissue. The inventive device is provided with a detection beam path comprising a lens system which couples radiation emanating from the tissue underneath the tissue surface into the detection beam path. A detector device generating a detection signal which indicates the spatial dimension and/or position of the optical penetration in the tissue is arranged downstream of the detection beam path.
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公开(公告)号：US20170258868A1
公开(公告)日：2017-09-14
申请号：US15602096
申请日：2017-05-22
CPC分类号： A61K38/10 , A61B3/102 , A61B3/1241 , A61F9/00821 , A61F2009/00851 , A61F2009/00863 , A61F2009/00865 , A61F2009/00872 , A61K38/08 , A61K45/06
摘要： The present invention relates to peptides for inhibiting angiogenesis. The present invention also relates to methods of inhibiting angiogenesis and methods of treating disorders associated with VEGF-induced vascular permeability using the peptides of the invention.
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公开(公告)号：US20170239088A1
公开(公告)日：2017-08-24
申请号：US15588405
申请日：2017-05-05
CPC分类号： A61F9/00825 , A61B3/0008 , A61B3/0025 , A61B3/102 , A61B3/14 , A61B90/39 , A61B2090/3937 , A61B2090/3979 , A61B2090/3983 , A61F9/00814 , A61F9/00817 , A61F9/0084 , A61F9/009 , A61F2009/00851 , A61F2009/0087 , A61F2009/00887 , A61F2009/00897
摘要： An ophthalmic system may comprise an imaging device having a field of view oriented toward the eye of the patient; a patient interface housing defining a passage therethrough, having a distal end coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of the patient, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage; and two or more registration fiducials coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing within the field of view of the imaging device such that they may be imaged by the imaging device in reference to predetermined geometric markers on the eye of the patient which may also be imaged by the imaging device.
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公开(公告)号：US20170216096A1
公开(公告)日：2017-08-03
申请号：US15433666
申请日：2017-02-15
发明人： Manfred DICK , Marcus BLUM , Matthias REICH
CPC分类号： A61F9/00825 , A61B18/20 , A61F9/008 , A61F9/00802 , A61F9/00804 , A61F9/00821 , A61F9/009 , A61F2009/00844 , A61F2009/00851 , A61F2009/00863 , A61F2009/0087 , A61F2009/00872 , A61F2009/00874 , A61F2009/00887
摘要： A device and a method for the femtosecond laser surgery of tissue, especially in the vitreous humor of the eye. The device includes an ultrashort pulse laser with pulse widths in the range of approximately 10 fs-1 ps, especially approximately 300 fs, pulse energies in the range of approximately 5 nJ-5 μJ, especially approximately 1-2 μJ and pulse repetition rates of approximately 10 kHz-10 MHz, especially 500 kHz. The laser system is coupled to a scanner system which allows the spatial variation of the focus in three dimensions (x, y and z). In addition to the therapeutic laser/scanner optical system, the device includes a navigation system.
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公开(公告)号：US09693903B2
公开(公告)日：2017-07-04
申请号：US15236284
申请日：2016-08-12
IPC分类号： A61B18/18 , A61F9/008 , A61F9/007 , A61F9/009 , A61B18/20 , A61F2/16 , A61B90/00 , A61B18/00
CPC分类号： A61F9/008 , A61B18/20 , A61B90/361 , A61B2018/00577 , A61F2/1602 , A61F9/00736 , A61F9/00754 , A61F9/00812 , A61F9/00814 , A61F9/00825 , A61F9/00831 , A61F9/00834 , A61F9/00836 , A61F9/00838 , A61F9/0084 , A61F9/009 , A61F2009/00844 , A61F2009/00851 , A61F2009/00865 , A61F2009/0087 , A61F2009/00878 , A61F2009/00882 , A61F2009/00887 , A61F2009/00889 , A61F2009/00895 , A61F2009/00897
摘要： A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.
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