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    Bioactive Compositions From Fruit and Methods for Their Production
    21.
    发明申请
    Bioactive Compositions From Fruit and Methods for Their Production 审中-公开
    水果生物活性成分及其生产方法

    公开(公告)号：US20160000848A1

    公开(公告)日：2016-01-07

    申请号：US14769877

    申请日：2014-03-12

    Applicant: AKZO NOBEL CHEMICALS INTERNATIONAL B.V.

    Inventor： Michael Koganov ,  Olga V. Dueva-Koganov ,  Artyom Duev ,  Steven Micceri

    IPC: A61K36/73

    CPC classification number: A61K36/73 ,  A61K36/185 ,  A61K36/45 ,  A61K36/736 ,  A61K36/752 ,  A61K36/81 ,  A61K36/88 ,  A61K2236/31 ,  A61K2236/37

    Abstract: The present invention relates to bioactive fractions (ingredients) derived from fruit juices. The bioactive fractions are either free of or substantially free of patulin and protein. Further, the bioactive fractions have antioxidant, free radical scavenging, moisturizing and buffering properties. The present invention also relates to a method for isolating bioactive fractions that are derived from fruit juices and are free or substantially free of protein and patulin. The present invention also relates to a method for preparing a bioactive fractions derived from fruit juices that are stabilized and are either free of or substantially free of patulin and protein.

    Abstract translation: 本发明涉及来自果汁的生物活性级分（成分）。 生物活性级分不含或基本上不含patulin和蛋白质。 此外，生物活性级分具有抗氧化，自由基清除，保湿和缓冲性能。 本发明还涉及一种用于分离衍生自果汁并且游离或基本上不含蛋白质和蛋白质的生物活性级分的方法。 本发明还涉及一种用于制备源自果汁的生物活性成分的方法，其稳定化并且不含或基本上不含蛋白和蛋白质。

    Method and process for relieving or preventing symptoms
    27.
    发明申请
    Method and process for relieving or preventing symptoms 审中-公开
    减轻或预防症状的方法和过程

    公开(公告)号：US20140044811A1

    公开(公告)日：2014-02-13

    申请号：US13998314

    申请日：2013-10-21

    Applicant: Kent J. Truscott ,  Susan M. Abernathy

    Inventor： Kent J. Truscott ,  Susan M. Abernathy

    IPC: A61K36/736 ,  A61K33/00 ,  A61K36/23

    CPC classification number: A61K36/736 ,  A61K9/0053 ,  A61K9/20 ,  A61K9/48 ,  A61K31/513 ,  A61K33/00 ,  A61K36/23 ,  A61K2300/00

    Abstract: A method for relieving or preventing symptoms associated with uric acid crystals, comprising consuming a formulation that supports three or more processes, the processes comprising: 1) one that inhibits formation of uric acid in the body; 2) one that increases elimination of uric acid from the body; and 3) one that interferes with formation of uric acid crystals in the body. Also, a process to make a formulation, comprising mixing together: i. a material that inhibits formation of uric acid in a body; ii. a material that increases elimination of uric acid from the body; iii. a material that interferes with formation of uric acid crystals in the body; and forming the mixture into a medicament.

    Abstract translation: 一种用于缓解或预防与尿酸晶体相关的症状的方法，包括消耗支持三种或更多种过程的制剂，所述方法包括：1）抑制体内尿酸形成的方法; 2）增加体内尿酸的消除; 和3）干扰体内尿酸晶体的形成。 此外，制备制剂的方法，包括混合在一起：i。 抑制体内尿酸形成的物质; ii。 增加尿酸从体内消除的物质; iii。 干扰体内尿酸晶体形成的物质; 并将混合物形成药物。

    COMPOSITION FOR PREVENTING OR TREATING DEMENTIA CONTAINING PRUNUS MUME EXTRACT
    28.
    发明申请
    COMPOSITION FOR PREVENTING OR TREATING DEMENTIA CONTAINING PRUNUS MUME EXTRACT 有权
    用于预防或治疗含有PRUNUS MUME提取物的DEMENTIA的组合物

    公开(公告)号：US20130309334A1

    公开(公告)日：2013-11-21

    申请号：US13996319

    申请日：2011-10-04

    Applicant: Won Kyung Jeon ,  Jung-Soo Han ,  Chang Hyun Han ,  Goya Choi

    Inventor： Won Kyung Jeon ,  Jung-Soo Han ,  Chang Hyun Han ,  Goya Choi

    IPC: A61K36/736

    CPC classification number: A61K36/736 ,  A61K2236/33

    Abstract: The present invention relates to a composition for preventing or treating dementia containing an extract of Prunus mume (Fructus Mume), and the Prunus mume extract of the present invention has outstanding effects in improving spatial recognition ability and in normalizing hippocampal damage (normalizing ERK phosphorylation, increasing ChAT and normalizing NF-kappa B) induced by chronic vascular brain damage in a vascular dementia animal model, and hence can be used to advantage as a medicinal product for preventing or treating dementia diseases and as a functional health food for preventing or alleviating dementia diseases that accompany vascular brain damage such as vascular dementia.

    Abstract translation: 本发明涉及用于预防或治疗含有李子提取物（Fructus Mume）的痴呆组合物，本发明的李属植物提取物具有突出的提高空间识别能力和正常化海马损伤的作用（归一化ERK磷酸化， 增加血管性痴呆动物模型中由慢性血管性脑损伤引起的ChAT和归一化NF-κB），因此可以用作预防或治疗痴呆疾病的药用产品，以及用作预防或减轻痴呆的功能性保健食品 血管性脑损伤如血管性痴呆的疾病。

    PROCESS FOR PYGEUM EXTRACTION
    30.
    发明申请
    PROCESS FOR PYGEUM EXTRACTION 有权
    萃取方法

    公开(公告)号：US20130236574A1

    公开(公告)日：2013-09-12

    申请号：US13877164

    申请日：2012-07-19

    Applicant: Kiran Tewari ,  Ashok Sharma

    Inventor： Kiran Tewari ,  Ashok Sharma

    IPC: A61K36/736 ,  A23L2/52 ,  A23L1/30

    CPC classification number: A61K36/736 ,  A23L2/52 ,  A23L33/105 ,  A61K2236/00

    Abstract: An improved process for the extraction of pygeum from the plant of the family rosacaea, amygdales tribe, genus Prunus species domestica (Indian Prunus) and related species (as herein defined) comprising the steps of collecting the plant material i.e. stem cuttings/twigs, removing the leaves and drying till moisture content is about 10-15%, powdering the stem material, extracting with chlorinated organic solvents and water-alcohol mixture, in ratio of 1:4, filtering and drying the extract under vacuum at 30 degree Celsius to obtain a greenish mass with bitter almond smell, the mass being referred to as ‘pygeum’ wherein in the improved process, a ‘renewable plant source’ i.e. stem cuttings/twigs, are used for extraction of pygeum instead of a ‘non-renewable’ source such as bark of the tree. The pygeum obtained by the new process has a pharmacopeia profile similar to the product ‘pygeum’ obtained from a ‘non-renewable source’ i.e. bark of Pygeum africanum. Further, it is non-toxic and shows anti-BPH (benign prostatic hyperplasia) activity comparable with that of pygeum obtained from non-renewable source i.e. bark of Prunus Africana.

    Abstract translation: 一种改进的从蔷薇科，杏仁属部落，本州属（Indian Prunus）和相关物种（如本文所定义）的植物中提取py草的方法，包括以下步骤：收集植物材料，即茎切片/枝条，去除 叶片干燥直到水分含量约为10-15％，粉碎茎材，用氯化有机溶剂和水 - 醇混合物萃取，比例为1：4，在30℃真空下过滤和干燥提取物，得到 一种具有苦杏仁气味的绿色群落，质量被称为“py”，其中在改进过程中，“可再生植物来源”（即茎扦插/枝杈）用于提取py草而不是“不可再生”来源 如树的树皮。 通过新方法获得的py木具有类似于从“不可再生来源”获得的产品“pygeum”的药典谱，即Pygeum africanum的树皮。 此外，它是无毒的并且显示与从非可再生来源（即非洲樱桃的皮）获得的py皮相比的抗BPH（良性前列腺增生）活性。

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