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    CHROMATOGRAPHY COLUMNS AND THEIR OPERATION
    22.
    发明申请
    CHROMATOGRAPHY COLUMNS AND THEIR OPERATION 审中-公开

    公开(公告)号：US20180015389A1

    公开(公告)日：2018-01-18

    申请号：US15716912

    申请日：2017-09-27

    申请人： Biotechflow Ltd

    发明人： Martin John Hofmann

    IPC分类号： B01D15/22 ,  G01C9/06

    CPC分类号： B01D15/22 ,  G01C9/06 ,  G01N30/6021 ,  G01N30/6047 ,  G01N30/6052 ,  G01N2030/565

    摘要： A chromatography column comprises a 2-axis inclinometer for determining or monitoring the orientation the axial verticality of the column tube or of a column component such as a piston. A column inclinometer may be mounted on the column. A piston inclinometer may be mounted on the piston. Outputs from the inclinometer may be fed to a programmable logic controller and used to control the operation of the column, e.g. by adjusting a support stand of the column, or controlling a piston drive mechanism.

    CHROMATOGRAPHY COLUMN ASSEMBLY
    26.
    发明申请
    CHROMATOGRAPHY COLUMN ASSEMBLY 审中-公开
    色谱柱组装

    公开(公告)号：US20160228792A1

    公开(公告)日：2016-08-11

    申请号：US15022813

    申请日：2014-08-15

    申请人： GE HEALTHCARE BIO-SCIENCES AB

    发明人： Veena Rao ,  Manoj Ramakrishna ,  Nikhil Kamble

    IPC分类号： B01D15/42 ,  C07K1/16 ,  G01N30/60

    CPC分类号： B01D15/424 ,  C07K1/16 ,  G01N30/6004 ,  G01N30/6021

    摘要： The invention relates to a chromatography column assembly that offers an affordable self-packed column for performing chromatographic separation. The chromatography column assembly comprises a column tube having a first and a second opening at substantially opposite ends, and an end cap of either a snap fit design or a bolted design. The column assembly may further include an adaptor shaft inserted into the column through the end cap for achieving a desired bed volume. The column assembly may also include a second end cap enclosing the second opening, and an optional adaptor shaft may be inserted into the column through the second end cap, enabling further adjustment of the bed volume.

    摘要翻译： 本发明涉及一种色谱柱组件，其提供了用于进行色谱分离的经济实惠的自填柱。 色谱柱组件包括具有在基本相对的端部处的第一和第二开口的柱管和卡扣配合设计或螺栓设计的端盖。 柱组件还可以包括通过端盖插入柱中的适配器轴，以实现所需的床体积。 柱组件还可以包括封闭第二开口的第二端盖，并且可选的适配器轴可以通过第二端盖插入柱中，使得能够进一步调节床体积。

    AN ARRANGEMENT FOR A COLUMN, A METHOD FOR SUBSTITUTING A TUBULAR HOUSING IN SUCH AN ARRANGEMENT FOR A COLUMN AND A METHOD FOR CONDUCTING PEPTIDE AND/OR OLIGONUCLEOTIDE SYNTHESIS IN A COLUMN
    27.
    发明申请
    AN ARRANGEMENT FOR A COLUMN, A METHOD FOR SUBSTITUTING A TUBULAR HOUSING IN SUCH AN ARRANGEMENT FOR A COLUMN AND A METHOD FOR CONDUCTING PEPTIDE AND/OR OLIGONUCLEOTIDE SYNTHESIS IN A COLUMN 审中-公开
    柱的布置，用于替换柱中的管状壳体的方法和用于在柱中导入肽和/或寡核苷酸合成的方法

    公开(公告)号：US20160152660A1

    公开(公告)日：2016-06-02

    申请号：US14904080

    申请日：2014-07-08

    申请人： GE HEALTHCARE BIO-SCIENCES AB

    发明人： Johan AVALLIN ,  Per DENKER

    IPC分类号： C07K1/02 ,  G01N30/60 ,  C07H1/06 ,  B01J19/24 ,  C07H21/00 ,  C07K1/16

    CPC分类号： C07K1/02 ,  B01D15/22 ,  B01J19/2415 ,  C07H1/06 ,  C07H21/00 ,  C07K1/16 ,  G01N30/6017 ,  G01N30/6021 ,  G01N30/6047 ,  G01N2030/8831

    摘要： An arrangement for a column comprising a stand provided with a platform adapted to receive a second end of a tubular housing and for supporting the arrangement on a floor, a first end unit removably connected to a first end of the tubular housing, an adaptor assembly movable within said tubular housing and an adaptor rod connected to said adaptor assembly, which adaptor rod is arranged to extend through an opening in the first end unit. A frame is connected to the first end unit, which frame and first end unit can be lifted and lowered in a substantially vertical direction, so that the tubular housing may be removed and substituted for another tubular housing with different dimensions in relation to the removed tubular housing when the frame and first end unit are lifted.

    摘要翻译： 一种用于柱的装置，其包括设置有平台的支架，所述平台适于容纳管状壳体的第二端并且用于将所述装置支撑在地板上，第一端部单元可移除地连接到所述管状壳体的第一端，可移动的适配器组件 在所述管状壳体内并且连接到所述适配器组件的适配杆，所述适配器杆被布置成延伸穿过所述第一端部单元中的开口。 框架连接到第一端单元，该框架和第一端单元可以在基本垂直的方向上升高和降低，使得可以移除管状壳体并且取代相对于移除的管状物的不同尺寸的另一个管状壳体 当框架和第一端单元被提起时，壳体。

    AN ADAPTOR FOR A CHROMATOGRAPHY COLUMN
    28.
    发明申请
    AN ADAPTOR FOR A CHROMATOGRAPHY COLUMN 审中-公开
    用于色谱柱的适配器

    公开(公告)号：US20150321121A1

    公开(公告)日：2015-11-12

    申请号：US14409593

    申请日：2013-06-18

    申请人： GE Healthcare Bio-Sciences AB

    发明人： Stefan Kjell ERIKSSON ,  Andreas BERGSTROM

    IPC分类号： B01D15/22 ,  G01N30/60 ,  B01D35/02

    CPC分类号： B01D15/22 ,  B01D35/02 ,  G01N30/56 ,  G01N30/6004 ,  G01N30/6017 ,  G01N30/6021 ,  G01N30/6047

    摘要： An adaptor for a chromatography column, the adaptor comprising a substantially circular bottom plate provided with an end surface; a ring shaped wall element arranged at the periphery of the bottom plate. The bottom plate and the wall element having a common axis and the adaptor is provided with a filter connection arrangement for removably connecting a filter on the end surface of the bottom plate of the adaptor.

    摘要翻译： 用于色谱柱的适配器，所述适配器包括设置有端面的基本上圆形的底板; 布置在底板周边的环形壁元件。 底板和具有共同轴线的壁元件和适配器设置有过滤器连接装置，用于可移除地连接适配器的底板的端面上的过滤器。

    Chromatography columns and their operation
    29.
    发明授权
    Chromatography columns and their operation 有权
    色谱柱及其操作

    公开(公告)号：US08715499B2

    公开(公告)日：2014-05-06

    申请号：US12558665

    申请日：2009-09-14

    申请人： Gerald James Spencer ,  Neil John Walker ,  John Mackay Scott

    发明人： Gerald James Spencer ,  Neil John Walker ,  John Mackay Scott

    IPC分类号： B01D15/22 ,  G01N30/60

    CPC分类号： G01N30/6021 ,  B01D15/22 ,  G01N30/603 ,  G01N30/6047 ,  G01N2030/522

    摘要： A method of operating chromatography column apparatus comprising a column tube (101) and first and second discrete end cell structures, associated with the respective ends of the column tube and positionable to close off the column tube and define therein a column space for retaining chromatography medium in use of the apparatus. The first end cell portion comprises a piston portion (106) fitting slidably in the column tube. The column tube and the second end cell structure are separated to provide an access spacing between them. The piston portion (106) of the first end cell structure is advanced through the column tube to expose it at the open second end of the column tube, for maintenance of the piston portion thus exposed. Corresponding chromatography apparatus is another aspect of the disclosure.

    摘要翻译： 一种操作色谱柱装置的方法，该色谱柱装置包括与柱管的相应端部相关联的柱管（101）和第一和第二离散端单元结构，并且可定位成将柱管封闭，并在其中限定用于保留色谱介质的柱空间 在使用该装置。 第一端部单元部分包括可滑动地装配在柱管中的活塞部分（106）。 柱管和第二端单元结构被分离以在它们之间提供进入间隔。 第一端部单元结构的活塞部分（106）通过柱管前进，以使其在柱管的开放的第二端处露出，以维持如此暴露的活塞部分。 相应的色谱装置是本公开的另一方面。