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3698 条记录 (耗时 0.031 秒)

    HEMAGGLUTININ-BINDING PEPTIDE
    22.
    发明公开
    HEMAGGLUTININ-BINDING PEPTIDE 审中-公开

    公开(公告)号：US20240228544A1

    公开(公告)日：2024-07-11

    申请号：US17432072

    申请日：2020-02-17

    申请人： PeptiDream Inc.

    发明人： Keiichi MASUYA ,  Masaki OHUCHI

    IPC分类号： C07K7/64 ,  A61K38/00 ,  A61P31/16 ,  G01N33/569

    CPC分类号： C07K7/64 ,  A61P31/16 ,  G01N33/56983 ,  A61K38/00 ,  G01N2333/11 ,  G01N2469/10

    摘要： [Problem to be solved] To provide a compound having markedly higher antiviral activity than iHA 100, an intermediate for producing the compound, and a medical drug, or the like, containing the high-activity compound above. [Solution] The invention relates to a hemagglutinin-binding peptide, a pharmaceutically acceptable salts, or a solvate thereof, the hemagglutinin-binding peptide being: (1) a polypeptide comprising the amino acid sequence represented by SEQ ID NO: 1 or 2: Trp-Thr-MeGly-Asp-MePhe-MePhe-Ala-MeAla-His-Tyr-Thr-Val-hydPro-Ala-Cys (SEQ ID NO: 1), Trp-Thr-MeGly-Asp-MePhe-MePhe-Ala-MeAla-His-Tyr-Thr-Val-hydPro-Ala-Cys-Lys (SEQ ID NO: 2), or the like.

    METHOD FOR DETECTING SUBSTANCE TO BE DETECTED WITHIN SAMPLE
    23.
    发明公开
    METHOD FOR DETECTING SUBSTANCE TO BE DETECTED WITHIN SAMPLE 审中-公开

    公开(公告)号：US20240210409A1

    公开(公告)日：2024-06-27

    申请号：US18567208

    申请日：2020-10-07

    申请人： NANOTIS CORPORATION

    发明人： Jinsei MIYAZAKI ,  Yoko NAGAI ,  Teruyuki NAGAMUNE ,  Lisa Kato

    IPC分类号： G01N33/58 ,  G01N21/64 ,  G01N33/569

    CPC分类号： G01N33/582 ,  G01N21/6428 ,  G01N33/56983 ,  G01N2021/6432 ,  G01N2021/6439 ,  G01N2333/11

    摘要： A method for detecting a substance within a sample, including: locally concentrating a substance to be detected, a material for recognizing the substance to be detected, or a binding product of a substance to be detected and a material for recognizing the substance to be detected within a sample by electrophoresis or dielectrophoresis; optionally binding the substance to be detected and the material for recognizing the substance to be detected in the sample; measuring changes in fluorescence intensity of a binding product of the substance to be detected and the material for recognizing the substance to be detected; and confirming the presence of the substance to be detected in the sample based on the measured fluorescence intensity, in which the material for recognizing the substance to be detected is labeled with a fluorescent substance that emits fluorescence at a specific wavelength and specifically recognizes and binds to the substance.

    Simultaneous disease detection system method and devices
    27.
    发明授权
    Simultaneous disease detection system method and devices 有权

    公开(公告)号：US12000823B2

    公开(公告)日：2024-06-04

    申请号：US17832632

    申请日：2022-06-04

    申请人： Matthew Hummer ,  Gregory J. Hummer

    发明人： Matthew Hummer ,  Gregory J. Hummer

    IPC分类号： G01N33/48 ,  G01N33/487 ,  G01N33/569 ,  G16H10/40

    CPC分类号： G01N33/48792 ,  G01N33/48714 ,  G01N33/4875 ,  G01N33/56983 ,  G16H10/40

    摘要： The embodiments disclose a method including providing impedimetric biosensor electrodes and circuits on a substrate, providing at least two different biopolymer materials on the conductive impedimetric biosensors electrodes and circuits, applying a predetermined electrical current to the impedimetric biosensor electrodes for establishing a baseline value, providing at least one biologic sample onto the impedimetric biosensors electrodes for detection of at least one disease microorganism, measuring the electrical current after contact with the at least one biologic sample for changes in the baseline value, recording changes in the electrical current measurements, analyzing the electrical current measurements for identifying predetermined detected disease microorganisms electrical current measurements changes, and determining the concentration of a detected disease microorganism.

    VIRUS DETECTION METHOD USING WELL ARRAY, WELL ARRAY, AND DETECTION DEVICE
    28.
    发明公开
    VIRUS DETECTION METHOD USING WELL ARRAY, WELL ARRAY, AND DETECTION DEVICE 审中-公开

    公开(公告)号：US20240168023A1

    公开(公告)日：2024-05-23

    申请号：US18552365

    申请日：2022-03-04

    申请人： NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY

    发明人： Makoto Fujimaki ,  Hiroki Ashiba

    IPC分类号： G01N33/569 ,  G01N33/543

    CPC分类号： G01N33/56983 ,  G01N33/54386 ,  G01N2333/11 ,  G01N2469/10

    摘要： An object is to detect a virus with high speed and high sensitivity. Provided is a virus detection method including using a well array formed by defining a plurality of wells adjacent to each other by a side wall stood on a substrate and detecting a virus in a test liquid based on the detection of light emission from the wells, wherein the well array has a test region in which a well formation area, which is an area of the substrate in a region where the wells are formed, is 5 mm2 or more, a total volume of the wells obtained by integrating individual volumes of the wells is 17 nL or more, a depth of the wells is 3.5 μm to 40 μm, an opening area of the wells is 18 μm2 to 1,700 μm2, a volume of the wells is 74 fL to 6,000 fL, and a thickness of the side wall between the wells adjacent to each other is 0.5 μm to 15 μm; and the detection of light emission from the wells is performed in a detection unit in which an observation visual field is fixed to have a size including the test region.