公开(公告)号：US07711842B2

公开(公告)日：2010-05-04

申请号：US11824240

申请日：2007-06-29

Applicant: Yang Liu ,  Larry James Wilson ,  Donald Franklin Smith, Jr. ,  William Todd Hasty ,  Todd Philip Cole

Inventor： Yang Liu ,  Larry James Wilson ,  Donald Franklin Smith, Jr. ,  William Todd Hasty ,  Todd Philip Cole

IPC: G06F13/00

CPC classification number: H04L67/06 ,  G06F19/00 ,  G07C5/008 ,  G07C5/085 ,  H04L67/125

Abstract: A method for data transfer between a client system and a server comprises receiving one or more user-defined file transfer specifications and establishing a communication channel between a client system and a server system based on the file transfer specifications. The method also includes initializing transfer of operation data between the client system and the server system via the communication channel. The method further includes providing an exception notification to one or more user-designated recipients if the transfer of the operation data between the client system and the server system is inconsistent with the file transfer specifications.

Abstract translation: 一种用于在客户端系统和服务器之间进行数据传输的方法包括：接收一个或多个用户定义的文件传输规范，并根据文件传输规范在客户机系统和服务器系统之间建立通信信道。 该方法还包括通过通信信道初始化客户端系统和服务器系统之间的操作数据的传送。 该方法还包括如果客户端系统与服务器系统之间的操作数据的传送与文件传输规范不一致，则向一个或多个用户指定的接收者提供异常通知。

公开(公告)号：US07652772B2

公开(公告)日：2010-01-26

申请号：US11803029

申请日：2007-05-11

Applicant: Vadim Backman ,  Hemant Roy ,  Young Kim ,  Yang Liu ,  Vladimir Turzhitsky ,  Jeremy Rogers

Inventor： Vadim Backman ,  Hemant Roy ,  Young Kim ,  Yang Liu ,  Vladimir Turzhitsky ,  Jeremy Rogers

IPC: G01B9/02

CPC classification number: G01J3/4412 ,  G01J3/02 ,  G01J3/0221 ,  G01J3/0224 ,  G01J3/10 ,  G01N21/31 ,  G01N21/47 ,  G01N2021/4709

Abstract: Systems, methods, and apparatuses of low-coherence enhanced backscattering spectroscopy are described within this application. One embodiment includes providing incident light comprising at least one spectral component having low coherence, wherein the incident light is to be illuminated on a target object in vivo. An intensity of one or more of at least one spectral component and at least one angular component of backscattering angle of backscattered light is recorded, wherein the backscattered light is to be backscattered from illumination of the incident light on the target object and wherein the backscattering angle is an angle between incident light propagation direction and backscattered light propagation direction. The intensity of the at least one spectral component and the at least one backscattering angle of backscattered light is analyzed, to obtain one or more optical markers of the backscattered light, toward evaluating said properties.

Abstract translation: 本申请中描述了低相干增强后向散射光谱的系统，方法和装置。 一个实施例包括提供包括具有低相干性的至少一个光谱分量的入射光，其中入射光将在体内照射在目标物体上。 记录至少一个光谱分量中的一个或多个光束分量和至少一个后向散射光的后向散射角度的角度分量的强度，其中后向散射光将从目标物体上入射光的照射反向散射，并且其中后向散射角 是入射光传播方向和反向散射光传播方向之间的角度。 分析至少一个光谱分量的强度和背散射光的至少一个后向散射角度，以获得反向散射光的一个或多个光学标记，以评估所述性质。

公开(公告)号：US20090324397A1

公开(公告)日：2009-12-31

申请号：US11671933

申请日：2007-02-06

Applicant: Philip Caruso ,  Dwight Davidson ,  Yang Liu ,  William Parker ,  Roger Walker ,  Sivaraman Vedhagiri

Inventor： Philip Caruso ,  Dwight Davidson ,  Yang Liu ,  William Parker ,  Roger Walker ,  Sivaraman Vedhagiri

IPC: F01D25/08

CPC classification number: F01D9/065 ,  F02C6/08 ,  F05D2260/231

Abstract: A gas turbine engine is provided comprising a compressor with an insulated cooling circuit. The compressor comprises a compressor casing having a compression chamber and at least one stator and at least one rotor disposed in the compression chamber, the at least one stator comprising a stator body having a plurality of tubes for transporting cooling air through passages in the stator body into the compression chamber. The plurality of tubes are surrounded by an air gap for insulating the tubes from the stator body.

Abstract translation: 提供一种燃气涡轮发动机，其包括具有绝缘冷却回路的压缩机。 压缩机包括压缩机壳体，其具有压缩室和至少一个定子以及设置在压缩室中的至少一个转子，所述至少一个定子包括具有多个管的定子体，所述多个管用于将冷却空气通过定子体中的通道传送 进入压缩室。 多个管被气隙包围，用于使管与定子体绝缘。

公开(公告)号：US20090252741A1

公开(公告)日：2009-10-08

申请号：US10536113

申请日：2005-09-07

Applicant: Yang Liu ,  Pan Zheng ,  Kenneth May, JR. ,  Ken Lute

Inventor： Yang Liu ,  Pan Zheng ,  Kenneth May, JR. ,  Ken Lute

IPC: A61K39/395 ,  C07K16/00 ,  C12Q1/02 ,  A61P37/04

CPC classification number: C07K16/2818 ,  A61K2039/505 ,  C07K2319/30

Abstract: Although results from preclinical studies in animal models have proven the concept for use of anti-CTLA-4 antibodies in cancer immunotherapy, two major obstacles have hindered their successful application for human cancer therapy. First, the lack of in vitro correlates of the anti-tumor effect of the antibodies makes it difficult to screen for the most efficacious antibody by in vitro analysis. Second, significant autoimmune side-effects have been observed In a recent clinical trial. In order to address these two issues, we have generated human CTLA-4 gene knock-in mice and used them to compare a panel of anti-human CTLA-4 antibodies for their ability to induce tumor rejection and autoimmunity. Surprisingly, while all antibodies induced protection against cancer and demonstrated some autoimmune side effects, the antibody that induced the strongest protection also induced the least autoimmune side effects. These results demonstrate that autoimmune disease does not quantitatively correlate with cancer immunity. Our approach may be generally applicable to the development of human therapeutic antibodies.

Abstract translation: 尽管动物模型临床前研究的结果证明了在抗癌免疫治疗中使用抗CTLA-4抗体的概念，但是两个主要障碍阻碍了其成功应用于人类癌症治疗。 首先，抗体的抗肿瘤作用的缺乏体外相关性使得难以通过体外分析筛选最有效的抗体。 第二，已经观察到显着的自身免疫副作用在最近的临床试验中。 为了解决这两个问题，我们产生了人CTLA-4基因敲入小鼠，并用它们来比较一组抗人CTLA-4抗体诱导肿瘤排斥和自身免疫的能力。 令人惊讶的是，虽然所有的抗体都能诱导对癌症的保护并且显示出一些自身免疫的副作用，但是诱导最强保护的抗体也诱导最小的自身免疫副作用。 这些结果表明，自身免疫性疾病与肿瘤免疫无定量关联。 我们的方法可能通常适用于人类治疗性抗体的开发。

公开(公告)号：US07483808B2

公开(公告)日：2009-01-27

申请号：US11819879

申请日：2007-06-29

Applicant: Jonny R. Greiner ,  Yang Liu

Inventor： Jonny R. Greiner ,  Yang Liu

IPC: G01L5/13 ,  G01L5/12 ,  G01L3/26 ,  G06F19/00 ,  G01M19/00

CPC classification number: G01M17/02

Abstract: A method of measuring rolling resistance of a machine is disclosed. The method may include determining a drive axle torque value of the machine and calculating a total effective grade value using the drive axle torque value. The method may further include determining at least one drivetrain efficiency loss factor value and calculating a total drivetrain efficiency loss value of the machine using the at least one drivetrain efficiency loss factor value. The method may also include determining position data of the machine and calculating an actual grade value based on the position data. The method may additionally include calculating a rolling resistance value of the machine by subtracting the actual grade value and the drivetrain efficiency loss value from the total effective grade value and outputting the rolling resistance value.

Abstract translation: 公开了一种测量机器滚动阻力的方法。 该方法可以包括确定机器的驱动轴扭矩值并使用驱动轴扭矩值计算总有效等级值。 该方法还可以包括使用至少一个传动系效率损失因子值来确定至少一个传动系效率损失因子值并计算机器的总传动系效率损失值。 该方法还可以包括确定机器的位置数据并基于位置数据计算实际坡度值。 该方法可以另外包括通过从总有效等级值中减去实际坡度值和传动系效率损失值并输出滚动阻力值来计算机器的滚动阻力值。

公开(公告)号：US20080278713A1

公开(公告)日：2008-11-13

申请号：US11891877

申请日：2007-08-13

Applicant: Vadim Backman ,  Yang Liu ,  Young Kim ,  Hemant Roy ,  Michael Goldberg ,  Randall Brand ,  Prabhakar Pradhan ,  Hariharan Subramanian

Inventor： Vadim Backman ,  Yang Liu ,  Young Kim ,  Hemant Roy ,  Michael Goldberg ,  Randall Brand ,  Prabhakar Pradhan ,  Hariharan Subramanian

IPC: G01N21/41 ,  G01N21/55

CPC classification number: G01N21/49 ,  A61B5/0062 ,  A61B5/0068 ,  A61B5/0075 ,  A61B5/0084 ,  G01N2021/4709

Abstract: Systems and methods for identifying refractive-index fluctuations of a target are described in this application. One embodiment includes identifying one or more properties of emergent light, the emergent light to be emergent from a target, and determining refractive-index fluctuations of the target based on the one or more properties of the emergent light. The determining refractive-index fluctuations further comprises determining one or more of the variance of the refractive-index fluctuations and the spatial correlation length of the refractive-index fluctuations. The determining refractive-index fluctuations further comprises determining one or more of the variance of the refractive-index fluctuations and the spatial correlation length of the refractive-index fluctuations.

Abstract translation: 在本申请中描述了用于识别目标的折射率波动的系统和方法。 一个实施例包括识别出射光的一个或多个属性，从目标出射的出射光，以及基于出射光的一个或多个属性来确定目标的折射率波动。 确定折射率波动还包括确定折射率波动的方差和折射率波动的空间相关长度的一个或多个。 确定折射率波动还包括确定折射率波动的方差和折射率波动的空间相关长度的一个或多个。

公开(公告)号：US20080247372A1

公开(公告)日：2008-10-09

申请号：US12099111

申请日：2008-04-07

Applicant: Hua Mary Chion ,  Hongyun Qu ,  Ling Xu ,  Jerry Pak Lup Chow ,  Yang Liu ,  Yuqin Chen

Inventor： Hua Mary Chion ,  Hongyun Qu ,  Ling Xu ,  Jerry Pak Lup Chow ,  Yang Liu ,  Yuqin Chen

IPC: H04Q7/24

CPC classification number: H04W72/005 ,  H04B7/2606 ,  H04W84/047

Abstract: Wireless communication relay networks and techniques for providing data synchronization in Multicast Broadcast Services (MBS).

Abstract translation: 用于在组播广播服务（MBS）中提供数据同步的无线通信中继网络和技术。

公开(公告)号：US06380808B1

公开(公告)日：2002-04-30

申请号：US09472245

申请日：1999-12-27

Applicant: Tachio Uasa ,  Yang Liu

Inventor： Tachio Uasa ,  Yang Liu

IPC: H03F318

CPC classification number: H03F3/3067 ,  H03F1/3217 ,  H03F3/3001

Abstract: A push-pull amplifier circuit includes a push-pull output circuit having a P-channel FET 11 and an N-channel FET 10 connected in series between supply potentials VDD and VSS, a gate potential difference circuit 16A having ends OP and ON connected to the gates of the FET 11 and FET 10, respectively, wherein the voltage VPN between OP and ON is adjusted depending on a control signal VG3, an input circuit 17 for changing potentials of OP and ON in response to an input voltage VI while keeping the voltage VPN between OP and ON substantially constant, a constant current source 40 for outputting a reference current IS, and an idle current detecting and comparing circuit 30 for detecting a current proportional to an idle current flowing through the FET 11 and FET 10 and generating a control signal VG3 for the circuit 16A so that the detected current approaches a reference current IS. In another configuration, there is provided a voltage control circuit for providing a potential VB=&agr;·VA−&bgr; to the gate of the FET 11 in response to a potential VA provided to the gate of the FET 10, where &agr; and &bgr; are predetermined values, and a constant current source connected in parallel to the FET 10 to flow the idle current.

Abstract translation: 推挽放大器电路包括一个推挽输出电路，其具有串联连接在电源电位VDD和VSS之间的P沟道FET 11和N沟道FET 10，栅极电位差电路16A的端部OP和ON连接到 FET 11和FET 10的栅极分别根据控制信号VG3调节OP和ON之间的电压VPN，输入电路17响应于输入电压VI改变OP和ON的电位，同时保持 OP和ON之间的电压VPN基本恒定，用于输出参考电流IS的恒定电流源40和用于检测与流过FET 11和FET 10的空闲电流成比例的电流的空闲电流检测和比较电路30， 用于电路16A的控制信号VG3，使得检测到的电流接近参考电流IS。 在另一种配置中，提供了一个电压控制电路，用于响应于提供给FET 10的栅极的电位VA，向FET 11的栅极提供电位VB = alpha.VA-β，其中α和β是预定的 值和与FET 10并联连接的恒流源以使空闲电流流动。