公开(公告)号：US11971615B2

公开(公告)日：2024-04-30

申请号：US17821079

申请日：2022-08-19

Applicant: ACUCELA INC.

Inventor： Ryo Kubota ,  Amitava Gupta

IPC: G02C7/08 ,  G02F1/29

CPC classification number: G02C7/083 ,  G02F1/294 ,  G02C2202/24

Abstract: An apparatus to treat refractive error of an eye comprises an electroactive component configured to switch between a light scattering or optical power providing configuration to treat refractive error of the eye and a substantially transparent configuration to allow normal viewing. The electroactive component can be located on the lens away from a central axis of the lens to provide light to a peripheral region of the retina to decrease the progression of myopia. The electroactive component can be located on the lens away from the central axis of the lens in order for the wearer to view objects through an optical zone while the electroactive component scatters light. The electroactive component can be configured to switch to the substantially transparent configuration to allow light to pass through the electroactive component and to allow the lens to refract light to correct vision and allow normal viewing through the lens.

公开(公告)号：US11860454B2

公开(公告)日：2024-01-02

申请号：US18175648

申请日：2023-02-28

Applicant: ACUCELA INC.

Inventor： Ryo Kubota ,  Philip M. Buscemi ,  Pascal Loser ,  Ben Crook ,  Massimo Pinazza ,  Jim Niebanck ,  James Phillips ,  Stefan Bauer

IPC: G02C5/14 ,  G02C7/08 ,  G02C11/00

CPC classification number: G02C7/083 ,  G02C5/146 ,  G02C11/10 ,  G02C2200/08

Abstract: An electronic case for electronic spectacles may include a base comprising a cavity formed therein. A first spectacle retention device may be located within the cavity. The first spectacle retention device may be configured to retain spectacles. An electrical control system may be included. An electrical connector may be configured to couple the electrical control system in electronic communication with the spectacles.

公开(公告)号：US20230324717A1

公开(公告)日：2023-10-12

申请号：US18330010

申请日：2023-06-06

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Philip M. BUSCEMI ,  Amitava GUPTA ,  Stefan BAUER ,  Benjamin CROOK ,  Julien SAUVET

IPC: G02C7/08 ,  G02C7/06 ,  G02C7/14 ,  G02C7/10 ,  G02C7/02

CPC classification number: G02C7/08 ,  G02C7/06 ,  G02C7/14 ,  G02C7/10 ,  G02C7/022 ,  G02C2202/24

Abstract: An apparatus to treat refractive error of an eye comprises an optic comprising an optical zone and a peripheral defocus optical structure to form images of a plurality of stimuli anterior or posterior to a peripheral portion of a retina of the eye. In some embodiments, the peripheral defocus optical structure located outside the optical zone. In some embodiments, the peripheral defocus optical structure comprises optical power to focus light to a different depth of the eye than the optical zone. In some embodiments, the optic comprises one or more of a lens, an optically transparent substrate, a beam splitter, a prism, or an optically transmissive support.

公开(公告)号：US11719957B2

公开(公告)日：2023-08-08

申请号：US17823208

申请日：2022-08-30

Applicant: ACUCELA INC.

Inventor： Ryo Kubota ,  Philip M. Buscemi ,  Amitava Gupta ,  Stefan Bauer ,  Benjamin Crook ,  Julien Sauvet

IPC: G02C7/08 ,  G02C7/06 ,  G02C7/14 ,  G02C7/10 ,  G02C7/02

CPC classification number: G02C7/08 ,  G02C7/022 ,  G02C7/06 ,  G02C7/10 ,  G02C7/14 ,  G02C2202/24

Abstract: An apparatus to treat refractive error of an eye comprises an optic comprising an optical zone and a peripheral defocus optical structure to form images of a plurality of stimuli anterior or posterior to a peripheral portion of a retina of the eye. In some embodiments, the peripheral defocus optical structure is located outside the optical zone. In some embodiments, the peripheral defocus optical structure comprises optical power to focus light to a different depth of the eye than the optical zone. In some embodiments, the optic comprises one or more of a lens, an optically transparent substrate, a beam splitter, a prism, or an optically transmissive support.

公开(公告)号：US20230144121A1

公开(公告)日：2023-05-11

申请号：US18153000

申请日：2023-01-11

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Karim HAROUD ,  Beat WYSS ,  Hans BERNHARD ,  Jean-Noel FEHR ,  Patrizia WEBER ,  Moritz HAEBERLI ,  Amitava GUPTA

IPC: A61N5/06 ,  G02B27/30 ,  G02B27/01

CPC classification number: A61N5/0622 ,  G02B27/30 ,  G02B27/0172 ,  A61N2005/063 ,  A61N2005/0648 ,  A61N2005/0652 ,  A61N2005/0663 ,  G02B2027/0178

Abstract: A device to stimulate the retina comprises one or more light sources coupled to one or more optical elements. The one or more optical elements is configured to illuminate the retina with one or more images at a location away from a fovea of a wearer. In some embodiments, each of the one or more images comprises a depth of focus and a spatial resolution. The one or more images can be formed at a distance anterior to the retina, at a distance posterior to the retina or on the retina. In some embodiments, the depth of focus is less than the distance, and the spatial resolution greater than a spatial resolution of the retina at the location.

公开(公告)号：US11620749B2

公开(公告)日：2023-04-04

申请号：US17805299

申请日：2022-06-03

Applicant: ACUCELA INC.

Inventor： Stephan Wyder ,  Matthias Pfister ,  Cyril Stoller ,  Philip M. Buscemi

IPC: G06T7/00 ,  G06T7/11 ,  G06T3/00 ,  G06V10/82 ,  G06N3/08 ,  G16H30/40

Abstract: A neural network is trained to segment interferogram images. A first plurality of interferograms are obtained, where each interferograms corresponds to data acquired by an OCT system using a first scan pattern, annotating each of the plurality of interferograms to indicate a tissue structure of a retina, training a neural network using the plurality of interferograms and the annotations, inputting a second plurality of interferograms corresponding to data acquired by an OCT system using a second scan pattern and obtaining an output of the trained neural network indicating the tissue structure of the retina that was scanned using the second scan pattern. The system and methods may instead receive a plurality of A-scans and output a segmented image corresponding to a plurality of locations along an OCT scan pattern.

公开(公告)号：US11619831B2

公开(公告)日：2023-04-04

申请号：US17806326

申请日：2022-06-10

Applicant: ACUCELA INC.

Inventor： Beat Wyss ,  Jean-Noël Fehr ,  Glenn Noronha ,  Karim Haroud ,  Julien Sauvet ,  Hans Bernhard ,  Christian Oggenfuss ,  Amitava Gupta ,  Ryo Kubota

IPC: G02C7/04 ,  G02C7/14 ,  G02C11/04

Abstract: A soft contact lens comprises a plurality of light sources coupled to a plurality of optical elements. The plurality of light sources and the plurality of optical elements are embedded in a soft contact lens material. Each of said plurality of optical elements generates an image focused in front of a peripheral retina of a wearer. In some embodiments, each of the images is focused at a distance in front of the peripheral retina at a location, and each of the images comprises a depth of focus and a spatial resolution. The depth of focus can be less than the distance, and the spatial resolution greater than a spatial resolution of the peripheral retina at the location.

公开(公告)号：US20230063265A1

公开(公告)日：2023-03-02

申请号：US17904450

申请日：2021-02-19

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Patrizia WEBER ,  Marco BURGENER ,  Jonas BUTSCHER ,  Praveenth SANMUGARAJAH ,  Hans BERNHARD ,  Amitava GUPTA

IPC: H02J50/10 ,  H02J50/40 ,  H02J7/00 ,  G02C7/04 ,  G02C11/00 ,  A45C11/00 ,  A45C15/00

Abstract: A contact lens charging case comprises a container sized and shaped to receive an electronic contact lens (“eCL”) and charging coil to couple to a coil of the eCL. In some embodiments, the charging coil comprises a diameter larger than a diameter of the coil of the eCL, so as to decrease sensitivity of the location and orientation of the eCL in the container and improve coupling between the coils. In some embodiments, the charging coil is dimensioned so as to extend at least partially around the container that receives the eCL.

公开(公告)号：US20220390766A1

公开(公告)日：2022-12-08

申请号：US17820493

申请日：2022-08-17

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Philip M. BUSCEMI ,  Pascal LOSER ,  Ben CROOK ,  Massimo PINAZZA ,  Jim NIEBANCK ,  James PHILLIPS ,  Stefan BAUER

IPC: G02C7/08 ,  G02C5/14 ,  G02C11/00

Abstract: An electronic case for electronic spectacles may include a base comprising a cavity formed therein. A first spectacle retention device may be located within the cavity. The first spectacle retention device may be configured to retain spectacles. An electrical control system may be included. An electrical connector may be configured to couple the electrical control system in electronic communication with the spectacles.

公开(公告)号：US20220382076A1

公开(公告)日：2022-12-01

申请号：US17753773

申请日：2020-09-15

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Jean-Noël FEHR ,  Hans BERNHARD ,  Patrizia WEBER ,  Alain SAURER ,  Amitava GUPTA

IPC: G02C7/04 ,  G02C11/00 ,  G02C11/04

Abstract: An opto-electronic module is configured to fit between anterior and posterior surfaces of a contact lens. The opto-electronics module may comprise a plurality of light sources configured to direct a plurality of light beams to a region of the retina away from the fovea and in some embodiments away from the macula. Each of the plurality of light sources may comprises an LED and one or more projection optics. Each of the projection optics can be coupled to an LED with an adhesive prior to placing the opto-electronics module on a layer of contact lens material. The opto-electronics module may comprise a flex PCB with the plurality of light sources, an antenna, a battery, a capacitor and a processor supported on the flex PCB.