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公开(公告)号：US20190011380A1
公开(公告)日：2019-01-10
申请号：US16030520
申请日：2018-07-09
发明人： Dallin S. Durfee , Jarom Jackson
IPC分类号： G01N23/20 , G01N23/046
摘要： A method of measuring an object is disclosed. In one step, a first interference pattern of interference waves is created. In another step, first measurement information is measured by measuring the scattering of the first interference pattern off the object, the transmission of the first interference pattern through the object, or the transmission of the first interference pattern around the object. In yet another step, a second interference pattern of interfered waves is created having a different shape or different scale than the first interference pattern. In another step, second measurement information is measured by measuring the scattering of the second interference pattern off the object, the transmission of the second interference pattern through the object, or the transmission of the second interference pattern around the object. In still another step, measurements of the object are determined using knowledge about shape of the first and second interference patterns and the first and second measurement information.
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公开(公告)号：US10119151B2
公开(公告)日：2018-11-06
申请号：US14103618
申请日：2013-12-11
摘要： Systems and methods for manipulating molecular material are provided. In one aspect, for example, a method for manipulating molecular material may include positioning an uncharged needle structure in electrical proximity with a charged molecular material at a first locus in a liquid environment, charging the needle structure such that at least a portion of the charged molecular material becomes associated with the needle structure, moving the needle structure and the first locus relative to one another, and discharging the needle structure to disassociate the charged molecular material at a second locus.
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公开(公告)号：US20180313856A1
公开(公告)日：2018-11-01
申请号：US15771174
申请日：2016-10-26
IPC分类号： G01N33/92
CPC分类号： G01N33/92
摘要： A panel of lipid biomarkers of preeclampsia in pregnant women, useful prior to onset of symptoms to identify women at risk of preeclampsia as early as 12-14 weeks gestation is disclosed. Methods of diagnosing a pregnant subject at risk of developing preeclampsia, and methods of reducing symptoms or preventing the onset of preeclampsia in a pregnant subject, employing the disclosed lipid biomarkers are also disclosed.
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公开(公告)号：US10095812B2
公开(公告)日：2018-10-09
申请号：US14925548
申请日：2015-10-28
摘要： A computer-implemented method for providing CAx data may include (1) storing a model of an engineering object as a group of nodes including one or more feature nodes, (2) associating a corresponding transaction history with each feature node, the transaction history indicating one or more states for a feature over time, and (3) determining a state of a selected feature node at a selected point in time by accessing the corresponding transaction history of the selected feature node. Various other methods and systems are also disclosed.
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35.发明申请公开(公告)号：US20180282901A1
公开(公告)日：2018-10-04
申请号：US15765964
申请日：2017-09-08
摘要： Embodiments disclosed herein are related to polycrystalline textured materials exhibiting heterogeneous templated grain growth, methods of forming such materials, and related systems. An example of a method of forming a polycrystalline textured material exhibiting heterogeneous templated grain growth includes providing a plurality of seeds. The method also includes aligning at least some of the plurality of seeds (e.g., single-crystal seeds) so that a selected crystallographic orientation of at least some of the plurality of seeds are substantially aligned with each other. Additionally, the method includes positioning the plurality of seeds in a powder matrix. The method then includes pressing the plurality of seeds and the powdered matrix to form a green body. Further, the method includes sintering the green body at a temperature that is sufficient to grow a plurality of grains from corresponding ones of the plurality of seeds to form the polycrystalline textured material.
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公开(公告)号：US20180274223A1
公开(公告)日：2018-09-27
申请号：US15516834
申请日：2016-12-08
摘要： Embodiments disclosed herein relate to a beam-to-column connection systems for a moment-resisting frame as well as moment-resisting frames that include such connection systems.
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公开(公告)号：US10070894B2
公开(公告)日：2018-09-11
申请号：US15006490
申请日：2016-01-26
发明人： Anton E. Bowden , Aubrie Taylor , Cassandra Bell
CPC分类号： A61B17/70 , A61B17/7044 , A61B17/8085 , A61B17/809 , A61B2017/564
摘要： In one general aspect, a vertebral attachment device can include an attachment member having a curved shape defining a concave surface, a flex structure included in the attachment member, and an anchor member coupled to the attachment member and protruding from the concave surface.
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公开(公告)号：US20180243506A1
公开(公告)日：2018-08-30
申请号：US15445377
申请日：2017-02-28
发明人： Jeffrey E. Niven , Jason Dearden , Peter S. Schleede , Andrew J. Moulton , Larry L. Howell , Spencer P. Magleby
CPC分类号： A61M5/3129 , A61M5/2033 , A61M5/3234 , A61M5/326 , A61M5/3287 , A61M5/46 , A61M2005/2026 , A61M2005/206 , A61M2005/314 , A61M2205/273 , A61M2205/276
摘要： An auto-injection syringe shaped similar to a credit card and having a biased injection mechanism operable to drive a needle into a user's body by a fixed distance to dispense a dose of fluid at a subcutaneous location. A safety may be provided to avoid undesired actuation of the injection mechanism. After the safety is bypassed, a trigger may be actuated by the user to allow operation of the injection mechanism. A reciprocating needle-cover resists casual view of the needle by the user during and after use of the syringe. A locking mechanism automatically holds the needle-cover at an extended position to isolate the needle from further contact and to resist re-use of the syringe.
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公开(公告)号：US10052749B2
公开(公告)日：2018-08-21
申请号：US14704327
申请日：2015-05-05
发明人： Christopher Mattson , Robert Campbell , Clark Davis , David Olligschlager , Brad Solomon , Samuel Wilding
CPC分类号： B25F5/001 , B25B21/00 , B25B21/02 , B25B23/0028 , B25F5/02
摘要： A drive train for supplying power to a power tool may include, a motor, a motor shaft, a rotational coupling mechanism connected to the motor shaft, and a drive shaft connected to the rotational coupling mechanism that forms the shape of a “U.” A pair of enmeshed bevel gears transfers the motion from the motor shaft to an orthogonal tool bit. The drive train may also include a hammering device that transfers a rotational impacting motion to the tool bit. A hand power tool for driving a screw may include a tool shell with an integrally formed vertical handle, a rotational recess formed into the tool shell opposite the handle, and a tool chuck within the rotational recess that drives a screw. The tool may incorporate the drive train as described above. The tool may include a mechanism for locking the tool chuck in a particular position.
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公开(公告)号：US20180100147A1
公开(公告)日：2018-04-12
申请号：US15727279
申请日：2017-10-06
发明人： Joshua Yates , Jonathon Hill
CPC分类号： C12N15/11 , C12N15/1082 , C12N15/113 , C12N2310/20 , C12N2310/531 , C12N2330/31
摘要： The disclosure generally relates to compositions, polynucleotides, kits, methods, and systems for generating clustered regularly interspaced short palindromic repeats (CRISPR) libraries. Disclosed are polynucleotides encoding for a constant region of a CRISPR single guide RNA (sgRNA) or CRISPR targeting RNA (crRNA) having a non-palindromic recognition site for a type II restriction enzyme oriented in a manner recognized by the type II restriction enzyme for cutting a site past an end of the polynucleotide. The methods include using the polynucleotide to prepare CRISPR libraries.
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