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    System and Method for Generating Theme Based Dynamic Groups
    31.
    发明申请
    System and Method for Generating Theme Based Dynamic Groups 审中-公开
    用于生成基于主题的动态组的系统和方法

    公开(公告)号：US20130311556A1

    公开(公告)日：2013-11-21

    申请号：US13475905

    申请日：2012-05-18

    申请人： Piyush Kumar Srivastava ,  Ashootosh Chand

    发明人： Piyush Kumar Srivastava ,  Ashootosh Chand

    IPC分类号： G06F15/16

    CPC分类号： G06Q50/01

    摘要： Methods, system and computer readable medium for generating a dynamic group includes defining a theme for the group. A group is initiated for the defined theme and plurality of users are invited to join the group. The activities of the plurality of users that have joined the group are monitored over time, wherein the activities are directed toward enriching information associated with the defined theme or one or more sub-themes of the defined theme. User dynamics of the group are adjusted dynamically based on the monitored activities of the users. The adjusted user dynamics define a strength value of the theme for the group of users.

    摘要翻译： 用于生成动态组的方法，系统和计算机可读介质包括定义该组的主题。 针对定义的主题启动一个组，并邀请多个用户加入组。 已经加入组的多个用户的活动随时间被监控，其中活动旨在丰富与所定义的主题相关联的信息或所定义主题的一个或多个子主题。 基于用户的监控活动，动态调整组的用户动态。 经调整的用户动态定义用户组的主题的强度值。

    Datacenter workflow automation scenarios using virtual databases
    33.
    发明授权
    Datacenter workflow automation scenarios using virtual databases 有权

    公开(公告)号：US08566361B2

    公开(公告)日：2013-10-22

    申请号：US13316263

    申请日：2011-12-09

    申请人： Charles Li Zha ,  Jedidiah Yueh ,  Alok Kumar Srivastava

    发明人： Charles Li Zha ,  Jedidiah Yueh ,  Alok Kumar Srivastava

    IPC分类号： G06F17/30

    CPC分类号： G06F17/30088 ,  G06F17/30144 ,  G06F17/30174 ,  G06F17/30566 ,  G06F17/30592

    摘要： Information from multiple databases is retrieved and stored on a database storage system. Multiple point-in-time copies are obtained for each database. A point-in-time copy retrieves data changed in the database since the retrieval of a previous point-in-time copy. A virtual database (VDB) is created by creating a set of files in the data storage system. Each file in the set of files created for a VDB is linked to the database blocks on the database storage system associated with a point-in-time copy of the source database. The set of files associated with the VDB are mounted on a database server allowing the database server to read from and write to the set of files. Workflows based on VDBs allow various usage scenarios based on databases to be implemented efficiently, for example, testing and development, backup and recovery, and data warehouse building.

    METHOD FOR PREDICTING AND MODELING ANTI-PSYCHOTIC ACTIVITY USING VIRTUAL SCREENING MODEL
    35.
    发明申请
    METHOD FOR PREDICTING AND MODELING ANTI-PSYCHOTIC ACTIVITY USING VIRTUAL SCREENING MODEL 审中-公开
    使用虚拟筛选模型预测和建模抗心理活动的方法

    公开(公告)号：US20130184462A1

    公开(公告)日：2013-07-18

    申请号：US13876658

    申请日：2011-09-30

    申请人： Santosh Kumar Srivastava ,  Feroz Khan ,  Shikha Gupta ,  Dharmendra K. Yadav ,  Vinay Kumar Khanna

    发明人： Santosh Kumar Srivastava ,  Feroz Khan ,  Shikha Gupta ,  Dharmendra K. Yadav ,  Vinay Kumar Khanna

    IPC分类号： G06F19/00

    CPC分类号： C07D459/00 ,  G16C20/30 ,  G16C20/50

    摘要： The present invention relates to the development of a virtual screening model for predicting antipsychotic activity using quantitative structure activity relationship (QSAR), molecular docking, oral bioavailability, ADME and Toxicity studies. The present invention also relates to the development of QSAR model using forward stepwise method of multiple linear regression with leave-one-out validation approach. QSAR model showed activity-descriptors relationship correlating measure (r2) 0.87 (87%) and predictive accuracy of 81% (rCV2=0.81). The present invention specifically showed strong binding affinity of the untested (unknown) novel compounds against anti-psychotic targets viz., Dopamine D2 and Serotonin (5HT2A) receptors through molecular docking approach. Theoretical results were in accord with the in vitro and in vivo experimental data. The present invention further showed compliance of Lipinski's rule of five for oral bioavailability and toxicity risk assessment for all the active Yohimbine derivatives. Therefore, use of developed virtual screening model will definitely facilitate the screening of more effective antipsychotic leads/drugs with improved antipsychotic activity and also reduced the drug discovery cost and duration.

    摘要翻译： 本发明涉及使用定量结构活性关系（QSAR），分子对接，口服生物利用度，ADME和毒性研究来预测抗精神病活性的虚拟筛选模型。 本发明还涉及使用多元线性回归的前向逐步方法与离开一个验证方法开发QSAR模型。 QSAR模型显示活动描述符关系相关度（r2）0.87（87％）和预测精度81％（rCV2 = 0.81）。 本发明通过分子对接方法具体显示未测试（未知）新化合物对抗精神病性靶标即多巴胺D2和5-羟色胺（5HT2A）受体的强结合亲和力。 理论结果符合体外和体内实验数据。 本发明进一步显示了所有活跃的育亨宾衍生物的Lipinski的五条规则符合口服生物利用度和毒性风险评估。 因此，使用开发的虚拟筛选模型肯定会有助于筛选更有效的抗精神病药物，抗精神病药物活性更好，降低药物发现成本和持续时间。

    Knowledge discovery appliance
    36.
    发明授权
    Knowledge discovery appliance 有权
    知识发现设备

    公开(公告)号：US08484217B1

    公开(公告)日：2013-07-09

    申请号：US13045028

    申请日：2011-03-10

    申请人： Manoj Kumar Srivastava ,  William Andrews Walker ,  Eric Alexander Olson ,  Steven Robert Smith

    发明人： Manoj Kumar Srivastava ,  William Andrews Walker ,  Eric Alexander Olson ,  Steven Robert Smith

    IPC分类号： G06F7/00 ,  G06F17/30

    CPC分类号： G06F17/30864 ,  G06F19/00 ,  Y02A90/26

    摘要： Methods and systems for collecting and processing large volumes of data to determine the relevancy and value thereof comprise: deploying one or more data retrieval modules to interface with one or more data sources within the local network, wherein the one or more data retrieval modules comprise executable program code; executing the one or more data retrieval modules to perform operations comprising: accessing application data representing data stored or communicated through the one or more data sources; and forwarding the application data for analysis; and analyzing the forwarded application data to determine whether it is relevant to the topic, wherein the analyzing is performed by one or more devices within the local network.

    摘要翻译： 用于收集和处理大量数据以确定其相关性和价值的方法和系统包括：将一个或多个数据检索模块部署到与本地网络内的一个或多个数据源接口，其中所述一个或多个数据检索模块包括可执行 程序代码; 执行所述一个或多个数据检索模块以执行操作，包括：访问表示通过所述一个或多个数据源存储或传达的数据的应用数据; 并转发应用数据进行分析; 以及分析所转发的应用数据以确定其是否与所述主题相关，其中所述分析由所述本地网络内的一个或多个设备执行。

    GENERATION OF USER PROFILES BASED ON FUTURE LOCATIONS
    38.
    发明申请
    GENERATION OF USER PROFILES BASED ON FUTURE LOCATIONS 审中-公开
    基于未来位置生成用户配置文件

    公开(公告)号：US20130103496A1

    公开(公告)日：2013-04-25

    申请号：US13276328

    申请日：2011-10-19

    申请人： Bharathi Shekar ,  Piyush Kumar Srivastava ,  Ashootosh Chand

    发明人： Bharathi Shekar ,  Piyush Kumar Srivastava ,  Ashootosh Chand

    IPC分类号： G06Q30/02 ,  G06F15/18

    CPC分类号： G06Q30/0201

    摘要： A computer-implemented method for generating user profiles based on future locations of a user includes receiving one or more future locations along with time duration of a user at each of the one or more future locations. The computer-implemented method also includes identifying a plurality of attributes associated with the one or more future locations. Further, the computer-implemented method includes inferring future interests of the user. Moreover, the computer-implemented method includes dynamically generating user profiles in accordance with the time duration of the user at each of the one or more future locations.

    摘要翻译： 用于基于用户的未来位置生成用户简档的计算机实现的方法包括在一个或多个未来位置的每一个处接收一个或多个未来位置以及用户的持续时间。 计算机实现的方法还包括识别与一个或多个未来位置相关联的多个属性。 此外，计算机实现的方法包括推断用户的未来兴趣。 此外，计算机实现的方法包括根据在一个或多个未来位置中的每一个处的用户的持续时间来动态地生成用户简档。

    Plasma ashing apparatus and endpoint detection process
    39.
    发明授权
    Plasma ashing apparatus and endpoint detection process 有权
    等离子灰化装置和端点检测过程

    公开(公告)号：US08268181B2

    公开(公告)日：2012-09-18

    申请号：US12552316

    申请日：2009-09-02

    申请人： Aseem Kumar Srivastava ,  Palanikumaran Sakthivel ,  Thomas James Buckley

    发明人： Aseem Kumar Srivastava ,  Palanikumaran Sakthivel ,  Thomas James Buckley

    IPC分类号： G01L21/30 ,  G01R31/00

    CPC分类号： H01L21/67253 ,  G03F7/427 ,  H01J37/32357 ,  H01J37/32834 ,  H01J37/32935 ,  H01J2237/3342 ,  H01L21/67069

    摘要： A plasma ashing apparatus for removing organic matter from a substrate including a low k dielectric, comprising a first gas source; a plasma generating component in fluid communication with the first gas source; a process chamber in fluid communication with the plasma generating component; an exhaust conduit in fluid communication with the process chamber; wherein the exhaust conduit comprises an inlet for a second gas source and an afterburner assembly coupled to the exhaust conduit, wherein the inlet is disposed intermediate to the process chamber and an afterburner assembly, and wherein the afterburner assembly comprises means for generating a plasma within the exhaust conduit with or without introduction of a gas from the second gas source; and an optical emission spectroscopy device coupled to the exhaust conduit comprising collection optics focused within a plasma discharge region of the afterburner assembly. An endpoint detection process for an oxygen free and nitrogen free plasma process comprises monitoring an optical emission signal of an afterburner excited species in an exhaust conduit of the plasma asher apparatus. The process and apparatus can be used with carbon and/or hydrogen containing low k dielectric materials.

    摘要翻译： 一种用于从包括第一气体源的低k电介质的衬底去除有机物质的等离子体灰化装置; 与所述第一气体源流体连通的等离子体产生部件; 与所述等离子体产生部件流体连通的处理室; 与处理室流体连通的排气管道; 其中所述排气管道包括用于第二气体源的入口和耦合到所述排气管道的后燃烧器组件，其中所述入口设置在所述处理室和加力燃烧器组件的中间，并且其中所述后燃烧器组件包括用于在所述排气管内产生等离子体的装置 具有或不从第二气体源引入气体的排气导管; 以及耦合到所述排气导管的光发射光谱装置，包括聚焦在所述后燃器组件的等离子体放电区域内的收集光学器件。 用于无氧和无氮等离子体工艺的端点检测方法包括监测等离子体灰化装置的排气管道中的后燃器激发物质的光发射信号。 该方法和装置可以与含有低k电介质材料的碳和/或氢一起使用。