公开(公告)号：US07175669B2

公开(公告)日：2007-02-13

申请号：US11222666

申请日：2005-09-09

Applicant: Kurt Geitz

Inventor： Kurt Geitz

IPC: A61F2/04

CPC classification number: A61F5/0076 ,  A61F2/04 ,  A61F2002/044 ,  A61F2210/0004

Abstract: A porous weave of bioabsorbable filaments is encased in an elastic membrane to form a thin-walled stent. The stent is sized to be snugly fitted in the proximate portion of the duodenum of a patient, to induce weight loss by limiting uptake of food passing through the stent. After a predetermined period, the stent degrades and passes from the body without surgical intervention.

Abstract translation: 生物可吸收长丝的多孔织物被包裹在弹性膜中以形成薄壁支架。 该支架的尺寸设计成紧密地配合在患者十二指肠的近端部分中，以通过限制通过支架的食物的摄取而引起体重减轻。 经过一段预定的时间后，支架会从身体退化而不进行手术干预。

公开(公告)号：US20060030949A1

公开(公告)日：2006-02-09

申请号：US11222666

申请日：2005-09-09

Applicant: Kurt Geitz

Inventor： Kurt Geitz

IPC: A61F2/04

CPC classification number: A61F5/0076 ,  A61F2/04 ,  A61F2002/044 ,  A61F2210/0004

Abstract: A porous weave of bioabsorbable filaments is encased in an elastic membrane to form a thin-walled stent. The stent is sized to be snugly fitted in the proximate portion of the duodenum of a patient, to induce weight loss by limiting uptake of food passing through the stent. After a predetermined period, the stent degrades and passes from the body without surgical intervention.

公开(公告)号：US06939374B2

公开(公告)日：2005-09-06

申请号：US10024261

申请日：2001-12-21

Applicant: Michael S. Banik ,  Kurt Geitz

Inventor： Michael S. Banik ,  Kurt Geitz

IPC: A61F2/00 ,  A61F2/82 ,  A61L31/16 ,  A61M25/00 ,  A61F2/06

CPC classification number: A61F2/82 ,  A61F2250/0068 ,  A61L31/16 ,  A61L2300/00 ,  A61M2025/0057 ,  A61M2025/1013 ,  A61M2025/105 ,  A61M2025/1086

Abstract: A stenting system for insertion into the lumen of a body duct or vessel for delivering a therapeutic agent to a treatment site on the duct or vessel. The stenting system includes an a tubular stent member having a lumen there through to allow the passage of material, an outer membrane attached to the stent at least a portion of which is porous to the therapeutic agent to allow the agent to pass to the treatment site, an inner membrane attached to the stent which is nonporous to the therapeutic agent to prevent the agent from entering the lumen of the stent, and a chamber located between the inner and outer membranes for holding the therapeutic agent. The therapeutic agent in the chamber may diffuse through the porous portion of the membrane and be deposited directly on the body site.

Abstract translation: 一种用于插入身体管道或血管的腔的支架系统，用于将治疗剂递送到管道或血管上的治疗部位。 所述支架系统包括管状支架构件，所述管状支架构件具有内腔，以允许材料通过;附接至所述支架的外膜，所述支架的至少一部分对于所述治疗剂是多孔的，以允许所述药剂通过所述治疗部位 附着到支架上的内膜，其与治疗剂无关，以防止药剂进入支架的内腔，以及位于内膜和外膜之间用于保持治疗剂的腔室。 腔室中的治疗剂可以扩散通过膜的多孔部分并直接沉积在身体部位上。

公开(公告)号：US20120165955A1

公开(公告)日：2012-06-28

申请号：US13408578

申请日：2012-02-29

Applicant: Kurt GEITZ

Inventor： Kurt GEITZ

IPC: A61F2/04

CPC classification number: A61F5/0036 ,  A61B17/0469 ,  A61B2017/00004 ,  A61B2017/00867 ,  A61F2/0036

Abstract: A porous weave of bioabsorbable filaments having an open mesh configuration is formed into an oblate shape having dimensions greater than the esophageal opening and gastric outlet of a stomach. The resulting prosthesis is deployed in the stomach and is of a size to be retained in the proximate portion thereof for exerting pressure on the upper fundus. The prosthesis limits the amount of food that may be held within the stomach, and exerts pressure on the fundus to create a sensation of being full, resulting in weight loss.

Abstract translation: 具有开口网状结构的生物可吸收长丝的多孔织物形成为尺寸大于胃的食管开口和胃出口的扁圆形状。 所产生的假体部署在胃中并且具有保持在其近端部分中的尺寸以在上眼底上施加压力。 假体限制了可能在胃中保持的食物的量，并且对眼底施加压力以产生充满的感觉，导致体重减轻。

公开(公告)号：US20120128793A1

公开(公告)日：2012-05-24

申请号：US13357017

申请日：2012-01-24

Applicant: Kathleen M. Miller ,  Gregory T. Sydney ,  Kurt Geitz ,  Peter L. Dayton ,  Ronald A. Sahatjian

Inventor： Kathleen M. Miller ,  Gregory T. Sydney ,  Kurt Geitz ,  Peter L. Dayton ,  Ronald A. Sahatjian

IPC: A01N31/14 ,  A01N37/40 ,  A61K33/24 ,  A61K31/519 ,  A61L29/16 ,  A61K31/337 ,  A61K31/573 ,  A01P1/00 ,  A61P35/00 ,  A61P29/00 ,  A01N37/52 ,  A61K31/704

CPC classification number: A61L2/232 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/202 ,  A61L2300/206 ,  A61L2300/21 ,  A61L2300/404 ,  A61L2300/45 ,  Y10T428/1334 ,  Y10T428/1352 ,  Y10T428/1372 ,  Y10T428/1379 ,  Y10T428/1386 ,  Y10T428/1393

Abstract: Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents

公开(公告)号：US08137338B2

公开(公告)日：2012-03-20

申请号：US12216789

申请日：2008-07-10

Applicant: Charles H. Pugsley ,  Marcia McBride-Sakal ,  Kurt Geitz

Inventor： Charles H. Pugsley ,  Marcia McBride-Sakal ,  Kurt Geitz

IPC: A61K9/22

CPC classification number: A61F13/00063 ,  A61F13/0213 ,  A61F13/0226 ,  A61F13/0253 ,  A61L15/40 ,  A61L15/64

Abstract: Endoluminally delivered tissue patches and related systems and methods for delivering the tissue patches for treating lesions of the alimentary tract are disclosed. A tissue patch includes a substrate, a tissue implant attached to the substrate, and a protective liner covering at least a portion of the tissue implant. A method includes providing a tissue patch having a tissue implant attached to a substrate and a protective liner covering at least a portion of the tissue implant. The tissue patch is formed into a contracted state and inserted into a lumen containing the lesion. The tissue patch then is positioned in the vicinity of the lesion. After removing the protective liner to reveal the tissue implant, the tissue implant is placed in the lesion.

Abstract translation: 公开了用于递送用于治疗消化道病变的组织贴片的内给药组织贴片和相关系统和方法。 组织贴片包括衬底，附着到衬底的组织植入物和覆盖组织植入物的至少一部分的保护衬垫。 一种方法包括提供具有附着到基底的组织植入物和覆盖组织植入物的至少一部分的保护性衬里的组织贴片。 组织贴片形成收缩状态并插入含有病变的内腔。 然后将组织贴片定位在病变附近。 在去除保护衬垫以露出组织植入物之后，将组织植入物放置在病变体内。

公开(公告)号：US08105520B2

公开(公告)日：2012-01-31

申请号：US11040864

申请日：2005-01-21

Applicant: Kathleen M. Miller ,  Gregory T. Sydney ,  Kurt Geitz ,  Peter L. Dayton ,  Ronald A. Sahatjian

Inventor： Kathleen M. Miller ,  Gregory T. Sydney ,  Kurt Geitz ,  Peter L. Dayton ,  Ronald A. Sahatjian

IPC: B29C63/06

CPC classification number: A61L2/232 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/202 ,  A61L2300/206 ,  A61L2300/21 ,  A61L2300/404 ,  A61L2300/45 ,  Y10T428/1334 ,  Y10T428/1352 ,  Y10T428/1372 ,  Y10T428/1379 ,  Y10T428/1386 ,  Y10T428/1393

Abstract: Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.

Abstract translation: 公开了可植入或可插入的医疗装置，其在装置的环境和环境中提供对微生物生长的抵抗力，并且抵抗微生物附着和在装置上的生物膜形成。 特别地，本发明公开了可植入或可插入的医疗装置，其包括至少一个生物相容性基质聚合物区域，用于提供对微生物生长的抗性的抗微生物剂和用于抑制微生物附着的微生物粘附/生物膜合成抑制剂以及合成和积累 生物膜在医疗器械的表面上。 还公开了在基本上防止任何所述生物活性剂优先分配到生物相容性基质聚合物的表面并基本上防止所述生物活性剂的化学修饰的条件下制造这种装置的方法。

公开(公告)号：US08062348B2

公开(公告)日：2011-11-22

申请号：US11061741

申请日：2005-02-22

Applicant: Michael S. Banik ,  Kurt Geitz

Inventor： Michael S. Banik ,  Kurt Geitz

IPC: A61F2/06

CPC classification number: A61F2/82 ,  A61F2250/0068 ,  A61L31/16 ,  A61L2300/00 ,  A61M2025/0057 ,  A61M2025/1013 ,  A61M2025/105 ,  A61M2025/1086

Abstract: A stenting system for insertion into the lumen of a body duct or vessel for delivering a therapeutic agent to a treatment site on the duct or vessel. The stenting system includes an a tubular stent member having a lumen there through to allow the passage of material, an outer membrane attached to the stent at least a portion of which is porous to the therapeutic agent to allow the agent to pass to the treatment site, an inner membrane attached to the stent which is nonporous to the therapeutic agent to prevent the agent from entering the lumen of the stent, and a chamber located between the inner and outer membranes for holding the therapeutic agent. The therapeutic agent in the chamber may diffuse through the porous portion of the membrane and be deposited directly on the body site.

Abstract translation: 一种用于插入身体管道或血管的腔的支架系统，用于将治疗剂递送到管道或血管上的治疗部位。 所述支架系统包括管状支架构件，所述管状支架构件具有内腔，以允许材料通过;附接至所述支架的外膜，所述支架的至少一部分对于所述治疗剂是多孔的，以允许所述药剂通过所述治疗部位 附着到支架上的内膜，其与治疗剂无关，以防止药剂进入支架的内腔，以及位于内膜和外膜之间用于保持治疗剂的腔室。 腔室中的治疗剂可以扩散通过膜的多孔部分并直接沉积在身体部位上。

公开(公告)号：US20110270405A1

公开(公告)日：2011-11-03

申请号：US13088671

申请日：2011-04-18

Applicant: Kurt Geitz ,  Claude Clerc

Inventor： Kurt Geitz ,  Claude Clerc

IPC: A61F2/04 ,  B21F33/00

CPC classification number: A61F2/90 ,  A61F2/848 ,  A61F5/0076 ,  A61F2002/045 ,  A61F2002/828 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2250/0039

Abstract: In at least one embodiment, the invention is directed to an endoluminal device comprising a stent and a sleeve. In one embodiment, the endoluminal device is implanted in a portion of the gastrointestinal tract. In some embodiments, the stent has a first region and a second region where the first and second regions provide different levels of radial force. In one embodiment, the first region is made from a plurality of first wires having a first diameter and the second region is made from a plurality of second wires having a second diameter which is smaller than the first diameter. In other embodiments, the endoluminal device has at least one engagement mechanism engaging the stent to the sleeve, the endoluminal device to a body lumen, and any combination thereof. In at least one embodiment, the endoluminal device has a wall with at least one opening therein.

Abstract translation: 在至少一个实施例中，本发明涉及一种包括支架和套管的腔内装置。 在一个实施例中，腔内装置植入胃肠道的一部分。 在一些实施例中，支架具有第一区域和第二区域，其中第一和第二区域提供不同水平的径向力。 在一个实施例中，第一区域由具有第一直径的多个第一布线制成，并且第二区域由具有小于第一直径的第二直径的多个第二布线制成。 在其它实施例中，腔内装置具有至少一个接合机构，其将支架接合到套筒，腔内装置到体腔及其任何组合。 在至少一个实施例中，腔内装置具有其中具有至少一个开口的壁。

公开(公告)号：US20100324696A1

公开(公告)日：2010-12-23

申请号：US12870977

申请日：2010-08-30

Applicant: Kurt GEITZ

Inventor： Kurt GEITZ

IPC: A61F2/04

CPC classification number: A61F5/0036 ,  A61B17/0469 ,  A61B2017/00004 ,  A61B2017/00867 ,  A61F2/0036

Abstract: A porous weave of bioabsorbable filaments having an open mesh configuration is formed into an oblate shape having dimensions greater than the esophageal opening and gastric outlet of a stomach. The resulting prosthesis is deployed in the stomach and is of a size to be retained in the proximate portion thereof for exerting pressure on the upper fundus. The prosthesis limits the amount of food that may be held within the stomach, and exerts pressure on the fundus to create a sensation of being full, resulting in weight loss.

Abstract translation: 具有开口网状结构的生物可吸收长丝的多孔织物形成为尺寸大于胃的食管开口和胃出口的扁圆形状。 所产生的假体部署在胃中并且具有保持在其近端部分中的尺寸以在上眼底上施加压力。 假体限制了可能在胃中保持的食物的量，并且对眼底施加压力以产生充满的感觉，导致体重减轻。