公开(公告)号：US20120160408A1

公开(公告)日：2012-06-28

申请号：US13335637

申请日：2011-12-22

Applicant: Claude Clerc ,  Gerald Fredrickson ,  Ralph J. Barry ,  Paul Norton ,  Kurt Geitz ,  Mike Madden

Inventor： Claude Clerc ,  Gerald Fredrickson ,  Ralph J. Barry ,  Paul Norton ,  Kurt Geitz ,  Mike Madden

IPC: B32B38/08 ,  A61L33/00

CPC classification number: B29C69/00 ,  A61L31/10 ,  B29C41/085 ,  B29C70/70 ,  B29K2021/00 ,  B29K2083/00 ,  B29K2627/18 ,  B29L2031/753 ,  B29L2031/758 ,  C08L27/18 ,  C08L83/04

Abstract: A medical device consists of a stent having a first surface and a second surface parallel to the first surface; a single expanded polytetrafluoroethylene (ePTFE) layer contacting the first surface of the stent; and an elastomeric layer applied to at least one surface of the stent. In at least one embodiment, the elastomeric layer is silicone. In at least one embodiment, the medical device is manufactured by positioning the ePTFE layer such that a first surface of the ePTFE layer contacts a first surface of the stent to form a stent-ePTFE assembly; and applying an elastomeric solution to the first surface of the ePTFE layer and at least one surface of the stent.

Abstract translation: 医疗装置由具有平行于第一表面的第一表面和第二表面的支架构成; 与支架的第一表面接触的单个膨胀聚四氟乙烯（ePTFE）层; 以及应用于支架的至少一个表面的弹性体层。 在至少一个实施方案中，弹性体层是有机硅。 在至少一个实施例中，通过定位ePTFE层使得ePTFE层的第一表面接触支架的第一表面以形成支架ePTFE组件来制造医疗装置; 以及将弹性体溶液施加到所述ePTFE层的第一表面和所述支架的至少一个表面。

公开(公告)号：US08974622B2

公开(公告)日：2015-03-10

申请号：US13335637

申请日：2011-12-22

Applicant: Claude Clerc ,  Gerald Fredrickson ,  Ralph Barry ,  Paul Norton ,  Kurt Geitz ,  Mike Madden

Inventor： Claude Clerc ,  Gerald Fredrickson ,  Ralph Barry ,  Paul Norton ,  Kurt Geitz ,  Mike Madden

IPC: B32B38/08 ,  A61L31/10 ,  B29C41/08 ,  B29C70/70 ,  B29K83/00 ,  B29K627/18 ,  B29L31/00

CPC classification number: B29C69/00 ,  A61L31/10 ,  B29C41/085 ,  B29C70/70 ,  B29K2021/00 ,  B29K2083/00 ,  B29K2627/18 ,  B29L2031/753 ,  B29L2031/758 ,  C08L27/18 ,  C08L83/04

Abstract: A medical device consists of a stent having a first surface and a second surface parallel to the first surface; a single expanded polytetrafluoroethylene (ePTFE) layer contacting the first surface of the stent; and an elastomeric layer applied to at least one surface of the stent. In at least one embodiment, the elastomeric layer is silicone. In at least one embodiment, the medical device is manufactured by positioning the ePTFE layer such that a first surface of the ePTFE layer contacts a first surface of the stent to form a stent-ePTFE assembly; and applying an elastomeric solution to the first surface of the ePTFE layer and at least one surface of the stent.

Abstract translation: 医疗装置由具有平行于第一表面的第一表面和第二表面的支架构成; 与支架的第一表面接触的单个膨胀聚四氟乙烯（ePTFE）层; 以及应用于支架的至少一个表面的弹性体层。 在至少一个实施方案中，弹性体层是有机硅。 在至少一个实施例中，通过定位ePTFE层使得ePTFE层的第一表面接触支架的第一表面以形成支架ePTFE组件来制造医疗装置; 以及将弹性体溶液施加到所述ePTFE层的第一表面和所述支架的至少一个表面。

公开(公告)号：US20110270405A1

公开(公告)日：2011-11-03

申请号：US13088671

申请日：2011-04-18

Applicant: Kurt Geitz ,  Claude Clerc

Inventor： Kurt Geitz ,  Claude Clerc

IPC: A61F2/04 ,  B21F33/00

CPC classification number: A61F2/90 ,  A61F2/848 ,  A61F5/0076 ,  A61F2002/045 ,  A61F2002/828 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2250/0039

Abstract: In at least one embodiment, the invention is directed to an endoluminal device comprising a stent and a sleeve. In one embodiment, the endoluminal device is implanted in a portion of the gastrointestinal tract. In some embodiments, the stent has a first region and a second region where the first and second regions provide different levels of radial force. In one embodiment, the first region is made from a plurality of first wires having a first diameter and the second region is made from a plurality of second wires having a second diameter which is smaller than the first diameter. In other embodiments, the endoluminal device has at least one engagement mechanism engaging the stent to the sleeve, the endoluminal device to a body lumen, and any combination thereof. In at least one embodiment, the endoluminal device has a wall with at least one opening therein.

Abstract translation: 在至少一个实施例中，本发明涉及一种包括支架和套管的腔内装置。 在一个实施例中，腔内装置植入胃肠道的一部分。 在一些实施例中，支架具有第一区域和第二区域，其中第一和第二区域提供不同水平的径向力。 在一个实施例中，第一区域由具有第一直径的多个第一布线制成，并且第二区域由具有小于第一直径的第二直径的多个第二布线制成。 在其它实施例中，腔内装置具有至少一个接合机构，其将支架接合到套筒，腔内装置到体腔及其任何组合。 在至少一个实施例中，腔内装置具有其中具有至少一个开口的壁。

公开(公告)号：US08663211B2

公开(公告)日：2014-03-04

申请号：US13562150

申请日：2012-07-30

Applicant: Michael Fourkas ,  Steven Walak ,  Kurt Geitz ,  Kristine Tatsutani

Inventor： Michael Fourkas ,  Steven Walak ,  Kurt Geitz ,  Kristine Tatsutani

IPC: A61B18/02

CPC classification number: A61B18/02 ,  A61B19/54 ,  A61B90/39 ,  A61B2017/00084 ,  A61B2017/22051 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2019/5437 ,  A61B2090/3937

Abstract: A cryogenic tissue ablation instrument includes an elongate flexible body with a proximal supply port for coupling with a pressurized coolant, a supply lumen in communication with the proximal supply port, and an expandable balloon carried on the elongate body. A dispersion member coupled to the elongate body has an interior lumen in communication with the supply lumen, the dispersion member having one or more coolant dispersion apertures sized and located such that a pressurized flowable coolant will enter the balloon interior in the form of a liquid spray that contacts and provides substantially uniform cooling of the balloon.

Abstract translation: 低温组织消融器具包括细长的柔性体，其具有用于与加压的冷却剂联接的近端供应口，与近端供应口连通的供应腔，以及承载在细长体上的可膨胀气囊。 耦合到细长主体的分散部件具有与供应内腔连通的内腔，分散部件具有一个或多个冷却剂分配孔，其尺寸和位置使得加压的可流动的冷却剂将以液体喷雾的形式进入气囊内部 其接触并提供气囊的基本上均匀的冷却。

公开(公告)号：US20120121665A1

公开(公告)日：2012-05-17

申请号：US13357033

申请日：2012-01-24

Applicant: Kathleen M. Miller ,  Gregory T. Sydney ,  Kurt Geitz ,  Peter L. Dayton ,  Ronald A. Sahatjian

Inventor： Kathleen M. Miller ,  Gregory T. Sydney ,  Kurt Geitz ,  Peter L. Dayton ,  Ronald A. Sahatjian

IPC: A61K9/00 ,  A61K31/704 ,  A61K31/519 ,  A61K31/337 ,  A61K31/56 ,  A61K47/32 ,  A61K31/085 ,  A61K31/155 ,  A61K31/60 ,  A61K31/197 ,  A61K31/573 ,  A61P31/00 ,  A61P35/00 ,  A61P29/00 ,  A61K33/24

CPC classification number: A61L2/232 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/202 ,  A61L2300/206 ,  A61L2300/21 ,  A61L2300/404 ,  A61L2300/45 ,  Y10T428/1334 ,  Y10T428/1352 ,  Y10T428/1372 ,  Y10T428/1379 ,  Y10T428/1386 ,  Y10T428/1393

Abstract: Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents

Abstract translation: 公开了可植入或可插入的医疗装置，其在装置的环境和环境中提供对微生物生长的抵抗力，并且抵抗微生物附着和在装置上的生物膜形成。 特别地，本发明公开了可植入或可插入的医疗装置，其包括至少一个生物相容性基质聚合物区域，用于提供对微生物生长的抗性的抗微生物剂和用于抑制微生物附着的微生物粘附/生物膜合成抑制剂以及合成和积累 生物膜在医疗器械的表面上。 还公开了在基本上防止任何所述生物活性剂优先分配到生物相容性基质聚合物的表面并基本上防止所述生物活性剂的化学修饰的条件下制造这种装置的方法

公开(公告)号：US20070162073A1

公开(公告)日：2007-07-12

申请号：US11715966

申请日：2007-03-09

Applicant: Kurt Geitz

Inventor： Kurt Geitz

IPC: A61B17/08

CPC classification number: A61B17/0643 ,  A61B17/00234 ,  A61B17/07207 ,  A61B17/10 ,  A61B2017/00827 ,  A61B2017/0647 ,  A61B2017/07214

Abstract: The present invention relates to devices and methods for creating and securing a tissue fold during an endoluminal medical procedure. The devices and methods may be used for folding and securing, for example, a fundus wall onto an esophagus wall. An aspect of the invention includes a two-piece tissue clip configured to be installed through an endoluminal device to secure a tissue fold. The clip includes a female member and a male member configured to engage one another to secure the tissue fold. Another aspect of the invention includes a clipping device comprising a tissue clip magazine. The magazine is configured to hold a plurality of tissue clips and install the plurality of tissue clips in a single actuation of the magazine. A method for using the clipping device together with the tissue clips of the present invention to create and secure a fold of tissue during an endoluminal procedure also is disclosed.

公开(公告)号：US07175669B2

公开(公告)日：2007-02-13

申请号：US11222666

申请日：2005-09-09

Applicant: Kurt Geitz

Inventor： Kurt Geitz

IPC: A61F2/04

CPC classification number: A61F5/0076 ,  A61F2/04 ,  A61F2002/044 ,  A61F2210/0004

Abstract: A porous weave of bioabsorbable filaments is encased in an elastic membrane to form a thin-walled stent. The stent is sized to be snugly fitted in the proximate portion of the duodenum of a patient, to induce weight loss by limiting uptake of food passing through the stent. After a predetermined period, the stent degrades and passes from the body without surgical intervention.

Abstract translation: 生物可吸收长丝的多孔织物被包裹在弹性膜中以形成薄壁支架。 该支架的尺寸设计成紧密地配合在患者十二指肠的近端部分中，以通过限制通过支架的食物的摄取而引起体重减轻。 经过一段预定的时间后，支架会从身体退化而不进行手术干预。

公开(公告)号：US20060030949A1

公开(公告)日：2006-02-09

申请号：US11222666

申请日：2005-09-09

Applicant: Kurt Geitz

Inventor： Kurt Geitz

IPC: A61F2/04

CPC classification number: A61F5/0076 ,  A61F2/04 ,  A61F2002/044 ,  A61F2210/0004

Abstract: A porous weave of bioabsorbable filaments is encased in an elastic membrane to form a thin-walled stent. The stent is sized to be snugly fitted in the proximate portion of the duodenum of a patient, to induce weight loss by limiting uptake of food passing through the stent. After a predetermined period, the stent degrades and passes from the body without surgical intervention.

公开(公告)号：US06939374B2

公开(公告)日：2005-09-06

申请号：US10024261

申请日：2001-12-21

Applicant: Michael S. Banik ,  Kurt Geitz

Inventor： Michael S. Banik ,  Kurt Geitz

IPC: A61F2/00 ,  A61F2/82 ,  A61L31/16 ,  A61M25/00 ,  A61F2/06

CPC classification number: A61F2/82 ,  A61F2250/0068 ,  A61L31/16 ,  A61L2300/00 ,  A61M2025/0057 ,  A61M2025/1013 ,  A61M2025/105 ,  A61M2025/1086

Abstract: A stenting system for insertion into the lumen of a body duct or vessel for delivering a therapeutic agent to a treatment site on the duct or vessel. The stenting system includes an a tubular stent member having a lumen there through to allow the passage of material, an outer membrane attached to the stent at least a portion of which is porous to the therapeutic agent to allow the agent to pass to the treatment site, an inner membrane attached to the stent which is nonporous to the therapeutic agent to prevent the agent from entering the lumen of the stent, and a chamber located between the inner and outer membranes for holding the therapeutic agent. The therapeutic agent in the chamber may diffuse through the porous portion of the membrane and be deposited directly on the body site.

Abstract translation: 一种用于插入身体管道或血管的腔的支架系统，用于将治疗剂递送到管道或血管上的治疗部位。 所述支架系统包括管状支架构件，所述管状支架构件具有内腔，以允许材料通过;附接至所述支架的外膜，所述支架的至少一部分对于所述治疗剂是多孔的，以允许所述药剂通过所述治疗部位 附着到支架上的内膜，其与治疗剂无关，以防止药剂进入支架的内腔，以及位于内膜和外膜之间用于保持治疗剂的腔室。 腔室中的治疗剂可以扩散通过膜的多孔部分并直接沉积在身体部位上。

公开(公告)号：US09034346B2

公开(公告)日：2015-05-19

申请号：US13357033

申请日：2012-01-24

Applicant: Kathleen M. Miller ,  Gregory T. Sydney ,  Kurt Geitz ,  Peter L. Dayton ,  Ronald A. Sahatjian

Inventor： Kathleen M. Miller ,  Gregory T. Sydney ,  Kurt Geitz ,  Peter L. Dayton ,  Ronald A. Sahatjian

IPC: A61L2/232 ,  A61L29/16 ,  A61L31/16

CPC classification number: A61L2/232 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/202 ,  A61L2300/206 ,  A61L2300/21 ,  A61L2300/404 ,  A61L2300/45 ,  Y10T428/1334 ,  Y10T428/1352 ,  Y10T428/1372 ,  Y10T428/1379 ,  Y10T428/1386 ,  Y10T428/1393

Abstract: Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.

Abstract translation: 公开了可植入或可插入的医疗装置，其在装置的环境和环境中提供对微生物生长的抵抗力，并且抵抗微生物附着和在装置上的生物膜形成。 特别地，本发明公开了可植入或可插入的医疗装置，其包括至少一个生物相容性基质聚合物区域，用于提供对微生物生长的抗性的抗微生物剂和用于抑制微生物附着的微生物粘附/生物膜合成抑制剂以及合成和积累 生物膜在医疗器械的表面上。 还公开了在基本上防止任何所述生物活性剂优先分配到生物相容性基质聚合物的表面并基本上防止所述生物活性剂的化学修饰的条件下制造这种装置的方法。