公开(公告)号：US20200309793A1

公开(公告)日：2020-10-01

申请号：US16860189

申请日：2020-04-28

Applicant: Meso Scale Technologies, LLC.

Inventor： Robert M. Umek ,  Pankaj Oberoi

IPC: G01N33/68

Abstract: Described are assay methods, modules and kits useful in the detection, treatment and/or prevention of dementia and related conditions, including but not limited to Alzheimer's disease and mild cognitive disorders.

公开(公告)号：US20200057070A1

公开(公告)日：2020-02-20

申请号：US16653268

申请日：2019-10-15

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. Glezer ,  Anu Mathew ,  Martin Stengelin ,  Mingyue Wang

IPC: G01N33/574

Abstract: The present invention relates to methods of diagnosing a liver disorder in a patient, as well as methods of monitoring the progression of a liver disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a chemotherapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

公开(公告)号：USD867614S1

公开(公告)日：2019-11-19

申请号：US29571999

申请日：2016-07-23

Applicant: Meso Scale Technologies, LLC.

Designer： Eric Jones ,  Jennifer Parker ,  Manish Kochar ,  Nicholas Sammons

公开(公告)号：US20190291103A1

公开(公告)日：2019-09-26

申请号：US16227081

申请日：2018-12-20

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. Glezer ,  Sudeep Kumar ,  Pankaj Oberoi ,  George Sigal ,  Michael Tsionsky

IPC: B01L3/00 ,  C12Q1/6804 ,  G01N33/68 ,  G01N33/543 ,  C12Q1/6816 ,  C12Q1/6876

Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.

公开(公告)号：US10408823B2

公开(公告)日：2019-09-10

申请号：US15311309

申请日：2015-05-15

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Anahit Aghvanyan ,  Eli N. Glezer ,  John Kenten ,  George Sigal ,  Martin Stengelin ,  David Routenberg

IPC: C12Q1/6832 ,  C12Q1/6837 ,  G01N33/543 ,  C12Q1/6844

Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.

公开(公告)号：US20190257823A1

公开(公告)日：2019-08-22

申请号：US16401513

申请日：2019-05-02

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. Glezer ,  Kent Johnson ,  Michael Tsionsky ,  John H. Kenten ,  Jeff D. Debad ,  Robert M. Umek ,  Paula Denney Eason ,  Hans Biebuyck ,  Jacob N. Wohlstadter ,  James Wilbur ,  George Sigal ,  Niranjan Y. Sardesai

IPC: G01N33/53 ,  G01N33/68 ,  G01N33/573 ,  G01N33/569 ,  C12Q1/48 ,  G01N33/543

Abstract: Multiplexed test measurements are conducted using an assay module having a plurality of assay domains. In preferred embodiments, these measurements are conducted in assay modules having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.

公开(公告)号：USD852975S1

公开(公告)日：2019-07-02

申请号：US29591550

申请日：2017-01-20

Applicant: Meso Scale Technologies, LLC

Designer： Eric Jones ,  Manish Kochar

公开(公告)号：US20190083976A1

公开(公告)日：2019-03-21

申请号：US16210165

申请日：2018-12-05

Applicant: Meso Scale Technologies, LLC

Inventor： Eli N. Glezer ,  Sudeep Kumar ,  Pankaj Oberoi ,  George Sigal ,  Michael Tsionsky

IPC: B01L3/00 ,  C12Q1/6804 ,  G01N33/68 ,  G01N33/543 ,  C12Q1/6876 ,  C12Q1/6816

Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.

公开(公告)号：US20180238882A1

公开(公告)日：2018-08-23

申请号：US15886020

申请日：2018-02-01

Applicant: Meso Scale Technologies, LLC.

Inventor： Michael Tsionsky ,  Eli N. Glezer ,  Selen Stromgren ,  George Sigal ,  Jonathan K. Leland ,  Mark A. Billadeau ,  Svetlana Leytner ,  Mark Martin ,  Larry Helms

IPC: G01N33/573 ,  G01N33/58 ,  C12Q1/48 ,  G01N21/76 ,  G01N33/53 ,  G01N33/543

Abstract: The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.

公开(公告)号：US20180088108A1

公开(公告)日：2018-03-29

申请号：US15813411

申请日：2017-11-15

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. Glezer ,  Anu Mathew

IPC: G01N33/543 ,  G01N33/574

CPC classification number: G01N33/543 ,  G01N33/57438 ,  G01N2800/52

Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.