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    Method for producing pressure sensitive poly (N-vinyl lactam)
    31.
    发明授权
    Method for producing pressure sensitive poly (N-vinyl lactam) 失效
    用于生产压敏聚（N-乙烯基内酰胺）粘合剂的方法

    公开(公告)号：US5409966A

    公开(公告)日：1995-04-25

    申请号：US137665

    申请日：1993-10-15

    Applicant: Daniel C. Duan ,  Robert A. Asmus ,  Timothy M. Dietz ,  Rosa Uy ,  Olester Benson, Jr.

    Inventor： Daniel C. Duan ,  Robert A. Asmus ,  Timothy M. Dietz ,  Rosa Uy ,  Olester Benson, Jr.

    IPC: A61B5/0408 ,  A61K9/70 ,  A61L15/58 ,  A61N1/30 ,  C08F20/26 ,  C08F20/52 ,  C08F26/10 ,  C08F220/28 ,  C08F220/56 ,  C08F226/10 ,  C09J137/00 ,  C09J139/04 ,  H01R4/04 ,  C08J3/28 ,  C09J139/06

    CPC classification number: A61K9/703 ,  A61K9/7053 ,  A61L15/58 ,  C09J139/04 ,  H01R4/04 ,  H01R2201/12 ,  Y10S522/912 ,  Y10S526/931

    Abstract: A hydrophilic, pressure-sensitive adhesive composition prepared by irradiating solid poly(N-vinyl lactam) with ionizing radiation to crosslink the poly(N-vinyl lactam) and thereafter mixing the radiation-crosslinked poly(N-vinyl lactam) with essentially unirradiated plasticizer in an amount sufficient to form a cohesive, pressure-sensitive adhesive composition. The composition is useful as a biomedical adhesive for transmitting or receiving electrical signals as a component of a biomedical electrode. The composition is also useful as a drug delivery device to deliver pharmaceuticals or other active ingredients to or through mammalian skin. The composition is also useful as a component in a skin covering for protecting mammalian skin Or mammalian skin openings with antimicrobial agents. A method of preparation of the composition is also disclosed.

    Abstract translation: 通过用电离辐射照射固体聚（N-乙烯基内酰胺）以交联聚（N-乙烯基内酰胺），然后将辐射交联的聚（N-乙烯基内酰胺）与基本上未照射的增塑剂混合而制备的亲水性压敏粘合剂组合物 其量足以形成粘合的压敏粘合剂组合物。 该组合物可用作生物医学粘合剂，用于作为生物医学电极的组分传输或接收电信号。 组合物还可用作药物递送装置，以将药物或其它活性成分递送至哺乳动物皮肤或通过哺乳动物皮肤。 组合物还可用作用于用抗微生物剂保护哺乳动物皮肤或哺乳动物皮肤开口的皮肤覆盖物中的组分。 还公开了组合物的制备方法。

    HYDROGELS WITH RELEASE ELEMENT
    33.
    发明申请
    HYDROGELS WITH RELEASE ELEMENT 有权
    带释放元件的水晶

    公开(公告)号：US20110166492A1

    公开(公告)日：2011-07-07

    申请号：US13119225

    申请日：2009-09-23

    Applicant: David R. Holm ,  Scott A. Burton ,  Robert A. Asmus ,  Richard L. Jacobson

    Inventor： David R. Holm ,  Scott A. Burton ,  Robert A. Asmus ,  Richard L. Jacobson

    IPC: A61F13/02 ,  A61L15/44 ,  A61L15/22

    CPC classification number: A61L15/60 ,  A61F13/0256 ,  A61F2013/00753 ,  A61L15/46 ,  A61L15/58 ,  A61L2300/404 ,  A61L2300/602

    Abstract: An adhesive hydrogel dressing as well as methods of applying the dressing to a patient. The dressing generally comprises an adhesive hydrogel pad, a backing layer, and an adhesive layer on the backing layer facing the hydrogel pad. The adhesive layer and backing layer form a perimeter around the hydrogel pad and hold the hydrogel pad in place on an application surface. A release element is in contact with at least a portion of the edge of the hydrogel pad proximate the area that the hydrogel pad and release liner separate during liner removal.

    Abstract translation: 粘合剂水凝胶敷料以及将敷料施用于患者的方法。 敷料通常包括粘合剂水凝胶垫，背衬层和位于背衬层上面向水凝胶垫的粘合剂层。 粘合剂层和背衬层形成围绕水凝胶垫的周边，并将水凝胶垫保持在施加表面上的适当位置。 释放元件与水凝胶垫的边缘的至少一部分接近邻近在衬垫移除期间水凝胶垫和释放衬垫分离的区域。

    STABLE HYDROALCOHOLIC COMPOSITIONS
    34.
    发明申请
    STABLE HYDROALCOHOLIC COMPOSITIONS 审中-公开
    稳定的水溶性组合物

    公开(公告)号：US20100331422A1

    公开(公告)日：2010-12-30

    申请号：US12878883

    申请日：2010-09-09

    Applicant: Robert A. Asmus ,  Matthew T. Scholz ,  Jill R. Charpentier

    Inventor： Robert A. Asmus ,  Matthew T. Scholz ,  Jill R. Charpentier

    IPC: A61K31/155 ,  A61K31/045 ,  A61P31/04 ,  A61P31/12 ,  A61P31/10

    CPC classification number: A61Q19/00 ,  A61K8/31 ,  A61K8/34 ,  A61K8/342 ,  A61K8/39 ,  A61K8/86 ,  A61K8/894 ,  A61K31/045 ,  A61Q17/005 ,  Y10S514/844 ,  Y10S514/938 ,  Y10S514/941

    Abstract: A hydroalcoholic lotion is disclosed which comprises (a) a lower alcohol and water in a weight ratio of about 35:65 to 100:0, and (b) between at least 0.5% and 8% by weight thickener system comprised of at least one emulsifier present in at least 0.05% by weight wherein the composition in a polymer free state has a viscosity of at least 4,000 centipoise at 23 degrees C. and wherein the emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The hydroalcoholic composition is useful as a hand preparation such as a lotion or as a presurgical scrub replacement.

    Abstract translation: 公开了一种水醇洗剂，其包含（a）重量比为约35:65至100:0的低级醇和水，和（b）至少0.5％至8％重量比的增稠剂体系，其包含至少一种 乳化剂以至少0.05重量％的量存在，其中无聚合物状态的组合物在23℃具有至少4,000厘泊的粘度，并且其中乳化剂由至少一个疏水基团和至少一个亲水基团组成。 水醇组合物可用作手制剂如洗剂或作为手术前洗涤剂。

    Skin antiseptic composition dispenser and methods of use
    35.
    发明授权
    Skin antiseptic composition dispenser and methods of use 有权
    皮肤防腐剂组合物分配器及使用方法

    公开(公告)号：US07261701B2

    公开(公告)日：2007-08-28

    申请号：US10263518

    申请日：2002-10-03

    Applicant: Robert A. Davis ,  Matthew T. Scholz ,  Mark V. Johnson ,  Triet M. Lu ,  Robert A. Asmus ,  John D. Dell

    Inventor： Robert A. Davis ,  Matthew T. Scholz ,  Mark V. Johnson ,  Triet M. Lu ,  Robert A. Asmus ,  John D. Dell

    IPC: A61M35/00 ,  B43K5/14 ,  A46B11/04

    CPC classification number: A61M35/006

    Abstract: Skin antiseptic composition dispensers and methods of use are disclosed. The skin antiseptic composition dispenser may include a container with one or more walls that are substantially impermeable to ethylene oxide gas during normal ethylene oxide sterilization processes. In some embodiments, the container may include flexible walls free of metallic foil barrier layers. The containers may also include one or more vents in addition to one or more openings used to dispense the skin antiseptic composition within the container. The dispenser may include an applicator with a hydrophilic foam.

    Abstract translation: 公开了皮肤防腐剂组合物分配器和使用方法。 皮肤消毒组合物分配器可以包括具有一个或多个壁的容器，所述壁在正常环氧乙烷灭菌过程中基本上不渗透环氧乙烷气体。 在一些实施例中，容器可以包括没有金属箔阻挡层的柔性壁。 除了用于分配容器内的皮肤消毒组合物的一个或多个开口之外，容器还可以包括一个或多个通气口。 分配器可以包括具有亲水性泡沫的涂布器。

    Sterilization indicator with chemically stabilized enzyme
    36.
    发明授权
    Sterilization indicator with chemically stabilized enzyme 有权
    具有化学稳定酶的灭菌指示剂

    公开(公告)号：US06897059B2

    公开(公告)日：2005-05-24

    申请号：US10014736

    申请日：2001-12-11

    Applicant: William E. Foltz ,  Robert A. Asmus ,  Ronald G. Lulich

    Inventor： William E. Foltz ,  Robert A. Asmus ,  Ronald G. Lulich

    IPC: A61L2/14 ,  A61L2/20 ,  A61L2/26 ,  A61L2/28 ,  C12Q1/22 ,  G01N31/22 ,  C12M1/34

    CPC classification number: G01N31/226 ,  A61L2/28 ,  C12Q1/22

    Abstract: A sterilization indicator for testing the effectiveness of a sterilization procedure comprises a source of an enzyme, a sterilant-resistant chemical associated with the enzyme, and a substrate that reacts with the enzyme to form a detectable enzyme-modified product that provides an indication of the failure of the sterilization procedure. The sterilant-resistant chemical may be a polyglycerol alkyl ester, polyglycerol alkyl ether, an ethoxylated polyhydric alcohol ester, or a polyhydric alcohol ether. The indicator may be used to test the effectiveness of a hydrogen peroxide plasma sterilization procedure and may be provided with a non-challenge test pack or a lumen-challenge test pack.

    Abstract translation: 用于测试灭菌程序的有效性的消毒指示剂包括酶的来源，与酶相关的杀菌剂抗性化学品，以及与酶反应形成可检测的酶修饰产物的底物，其提供 灭菌程序失败。 杀菌剂抗性化学品可以是聚甘油烷基酯，聚甘油烷基醚，乙氧基化多元醇酯或多元醇醚。 该指示剂可用于测试过氧化氢等离子体灭菌方法的有效性，并且可以提供非挑战性测试包或流明挑战测试包。

    Sterilization indicator with chemically stabilized enzyme
    38.
    发明授权
    Sterilization indicator with chemically stabilized enzyme 有权
    具有化学稳定酶的灭菌指示剂

    公开(公告)号：US06355448B1

    公开(公告)日：2002-03-12

    申请号：US09228712

    申请日：1999-01-12

    Applicant: William E. Foltz ,  Robert A. Asmus ,  Ronald G. Lulich

    Inventor： William E. Foltz ,  Robert A. Asmus ,  Ronald G. Lulich

    IPC: C12Q122

    CPC classification number: G01N31/226 ,  A61L2/28 ,  C12Q1/22

    Abstract: A sterilization indicator for testing the effectiveness of a sterilization procedure comprises a source of an enzyme, a sterilant-resistant chemical associated with the enzyme, and a substrate that reacts with the enzyme to form a detectable enzyme-modified product that provides an indication of the failure of the sterilization procedure. The sterilant-resistant chemical may be a polyglycerol alkyl ester, polyglycerol alkyl ether, an ethoxylated polyhydric alcohol ester, or a polyhydric alcohol ether. The indicator may be used to test the effectiveness of a hydrogen peroxide plasma sterilization procedure and may be provided with a non-challenge test pack or a lumen-challenge test pack.

    Abstract translation: 用于测试灭菌程序的有效性的消毒指示剂包括酶的来源，与酶相关的杀菌剂抗性化学品，以及与酶反应形成可检测的酶修饰产物的底物，其提供 灭菌程序失败。 杀菌剂抗性化学品可以是聚甘油烷基酯，聚甘油烷基醚，乙氧基化多元醇酯或多元醇醚。 该指示剂可用于测试过氧化氢等离子体灭菌方法的有效性，并且可以提供非挑战性测试包或流明挑战测试包。

    Stable hydroalcoholic compositions
    39.
    发明授权
    Stable hydroalcoholic compositions 有权
    稳定的水醇组合物

    公开(公告)号：US06352701B1

    公开(公告)日：2002-03-05

    申请号：US09320590

    申请日：1999-05-27

    Applicant: Matthew T. Scholz ,  Robert A. Asmus ,  Jill R. Charpentier

    Inventor： Matthew T. Scholz ,  Robert A. Asmus ,  Jill R. Charpentier

    IPC: A01N2500

    CPC classification number: A61K8/34 ,  A61K8/342 ,  A61K8/37 ,  A61K8/39 ,  A61K8/416 ,  A61K8/604 ,  A61K8/86 ,  A61Q17/005 ,  A61Q19/00 ,  Y10S514/846 ,  Y10S514/873 ,  Y10S514/944 ,  Y10S514/945 ,  Y10S514/946 ,  Y10S514/975

    Abstract: Disclosed is a composition including a lower alcohol and water in a weight ratio of about 35:65 to 100:0, between at least 0.5% and 8.0% by weight thickener system comprised of at least two emulsifiers, each emulsifier present in at least 0.05% by weight wherein the composition free of auxiliary thickeners has a viscosity of at least 4,000 centipoise at 23 degrees C. and wherein each emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The composition is useful as a presurgical scrub replacement, a lotion or other hand preparation.

    Abstract translation: 公开了包含低级醇和水的组合物，其重量比为约35:65至100:0，至少0.5重量％至8.0重量％的由至少两种乳化剂组成的增稠剂体系，每种乳化剂存在于至少0.05 重量％，其中不含辅助增稠剂的组合物在23℃具有至少4,000厘泊的粘度，并且其中每个乳化剂由至少一个疏水基团和至少一个亲水基团组成。 组合物可用作术前洗刷替代物，洗剂或其他手制剂。

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