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公开(公告)号：US20180353555A1
公开(公告)日：2018-12-13
申请号：US15995393
申请日：2018-06-01
Applicant: Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed
Inventor： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed
IPC: A61K35/742 , C12N1/20 , A61P1/14
Abstract: Disclosed are the methods and compositions for the reduction of intestinal gas/flatulence. Specifically a method for reducing flatulence using a composition containing probiotic bacteria Bacillus coagulans MTCC 5856 is disclosed. More specifically, the invention discloses a method for inhibiting the growth of microorganisms that facilitate the production of intestinal gas, using a composition containing probiotic bacteria Bacillus coagulans MTCC 5856.
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公开(公告)号：US20180344754A1
公开(公告)日：2018-12-06
申请号：US16001096
申请日：2018-06-06
Applicant: Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed
Inventor： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed
IPC: A61K31/7024 , A61K35/742 , A61P31/04
Abstract: Disclosed are compositions containing at least 10% w/w or above of 1-O-galloyl-β-D-glucose (β-glucogallin) which additionally comprising of about 10% w/w to greater than 60% w/w total mucic acid gallates including mucic acid 1,4-lactone 5-O-gallate, mucic acid 2-O-gallate, mucic acid 6-Methyl ester 2-O-gallate, mucic acid 1-Methyl ester 2-O-gallate and ellagic acid, and a probiotic bacteria Bacillus coagulans MTCC 5856, individually or in combination for inhibiting the growth and managing infections of Helicobacter pylori.
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33.发明授权公开(公告)号：US09717766B2
公开(公告)日：2017-08-01
申请号：US14839923
申请日：2015-08-29
Applicant: Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali
Inventor： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali
CPC classification number: A61K35/742 , A61K36/45 , A61K36/47 , A61K36/48 , A61K36/55 , A61K36/68 , A61K36/815 , A61K36/889 , A61K36/9068 , A61K2035/115 , A61P5/50 , C12N1/20 , C12P7/6409 , Y02A50/473 , A61K2300/00
Abstract: The present invention disclosed herein describes (i) the growth promotional activity of natural plant based fibres on Bacillus coagulans MTCC 5856; (ii) the combination of natural plant based fibres and Bacillus coagulans MTCC 5856 to inhibit Gram Negative pathogenic bacteria and (iii) the production of short chain fatty acids (SCFA) by Bacillus coagulans MTCC 5856 using plant based natural fibres.
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公开(公告)号：US09681665B2
公开(公告)日：2017-06-20
申请号：US15214669
申请日：2016-07-20
Applicant: Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali
Inventor： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali
IPC: A61K35/00 , A01N63/02 , C12N1/20 , C12R1/07 , A01N31/08 , A01N37/12 , C12R1/085 , C12R1/19 , C12R1/385 , C12R1/42 , C12R1/445 , C12R1/45 , C12R1/46
CPC classification number: A01N63/02 , A01N31/08 , A01N37/12 , C12N1/20 , C12R1/07 , C12R1/085 , C12R1/19 , C12R1/385 , C12R1/42 , C12R1/445 , C12R1/45 , C12R1/46 , A01N65/08
Abstract: The antimicrobial effect of extracellular metabolite composition from Bacillus coagulans MTCC 5856 is described.
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公开(公告)号：US09635862B2
公开(公告)日：2017-05-02
申请号：US15214699
申请日：2016-07-20
Applicant: Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali
Inventor： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali
IPC: A61K35/00 , A01N63/02 , C12N1/20 , C12R1/07 , A01N31/08 , A01N37/12 , C12R1/085 , C12R1/19 , C12R1/385 , C12R1/42 , C12R1/445 , C12R1/45 , C12R1/46
CPC classification number: A01N63/02 , A01N31/08 , A01N37/12 , C12N1/20 , C12R1/07 , C12R1/085 , C12R1/19 , C12R1/385 , C12R1/42 , C12R1/445 , C12R1/45 , C12R1/46 , A01N65/08
Abstract: Process of inhibiting microbial biofilm formation using extracellular metabolite composition from Bacillus coagulans MTCC 5856 and composition comprising from about 61% w/w of thymol, about 38% w/w of monolaurin and about 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis is described.
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Patent Agency Ranking
36.发明申请公开(公告)号：US20160324162A1
公开(公告)日：2016-11-10
申请号：US15214685
申请日：2016-07-20
Applicant: Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali
Inventor： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali
IPC: A01N63/02
CPC classification number: A01N63/02 , A01N31/08 , A01N37/12 , C12N1/20 , C12R1/07 , C12R1/085 , C12R1/19 , C12R1/385 , C12R1/42 , C12R1/445 , C12R1/45 , C12R1/46 , A01N65/08
Abstract: Disclosed is a method for producing partially purified extracellular metabolite preparation from the probiotic bacterial strain Bacillus coagulans SBC-37 (Deposited in the Microbial Type Culture Collection and Gene Bank as strain number MTCC 5856) exhibiting 99% genetic homology with the known bacterial strains Bacillus coagulans ATCC 31284, Bacillus coagulans NBRC 3887 and Bacillus coagulans ATCC 7050. Also disclosed is the anti-microbial profile of said extracellular metabolite preparation against a panel of microbial pathogens, including synergistic anti-microbial effects of preparation when combined with a synergistic preservative blend comprising from about 61% w/w of thymol, about 38% of monolaurin and about 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis. The extracellular metabolite preparation alone or the combination of said extracellular metabolite preparation and preservative blend also inhibits microbial biofilm formation in a synergistic manner.
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37.发明申请公开(公告)号：US20150173374A1
公开(公告)日：2015-06-25
申请号：US14576411
申请日：2014-12-19
Applicant: Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali
Inventor： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali
CPC classification number: A01N63/02 , A01N31/08 , A01N37/12 , C12N1/20 , C12R1/07 , C12R1/085 , C12R1/19 , C12R1/385 , C12R1/42 , C12R1/445 , C12R1/45 , C12R1/46 , A01N65/08
Abstract: Disclosed is a method for producing partially purified extracellular metabolite preparation from the probiotic bacterial strain Bacillus coagulans SBC-37 (Deposited in the Microbial Type Culture Collection and Gene Bank as strain number MTCC 5856) exhibiting 99% genetic homology with the known bacterial strains Bacillus coagulans ATCC 31284, Bacillus coagulans NBRC 3887 and Bacillus coagulans ATCC 7050. Also disclosed is the anti-microbial profile of said extracellular metabolite preparation against a panel of microbial pathogens, including synergistic anti-microbial effects of preparation when combined with a synergistic preservative blend comprising from about 61% w/w of thymol, about 38% of monolaurin and about 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis. The extracellular metabolite preparation alone or the combination of said extracellular metabolite preparation and preservative blend also inhibits microbial biofilm formation in a synergistic manner.
Abstract translation: 公开了一种从已知菌株凝结芽孢杆菌（Bacillus coagulans）显示出99％的遗传同源性的益生菌菌株凝结芽孢杆菌凝结芽孢杆菌SBC-37（沉积在微生物型培养物收集和基因库中的菌株号MTCC 5856）的部分纯化细胞外代谢物制剂的方法。 ATCC 31284，凝结芽孢杆菌NBRC 3887和凝结芽孢杆菌ATCC 7050.还公开了所述细胞外代谢产物针对一组微生物病原体的抗微生物特征，包括与协同防腐混合物组合时的制备的协同抗微生物作用， 约61％w / w的百里酚，约38％的单月桂酸和约1％w / w的从木兰超临界流体提取物获得的厚朴酚。 单独的胞外代谢物制剂或所述细胞外代谢物制剂和防腐剂混合物的组合也以协同方式抑制微生物生物膜形成。
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公开(公告)号：US20220145244A1
公开(公告)日：2022-05-12
申请号：US17431036
申请日：2020-02-14
Applicant: Muhammed Majeed , Kalyanam Nagabhushanam , Natarajan Sankaran , Sivakumar Arumugam , Muthuraman Gnanamani , Kulithalai Viswanathan Krishnamurthy , Ugraiah Amilineni
Inventor： Muhammed Majeed , Kalyanam Nagabhushanam , Natarajan Sankaran , Sivakumar Arumugam , Muthuraman Gnanamani , Kulithalai Viswanathan Krishnamurthy , Ugraiah Amilineni
IPC: C12N5/04
Abstract: The present invention discloses a method of isolating secondary metabolites, specifically arjunolic acid, from the calli and/or the suspension cultures derived from the pluripotent cambium tissue of Terminalia arjuna. The invention also discloses a method of inducing callus, establishing and maintaining suspension cultures of callus derived from the cambium of Terminalia arjuna for the isolation of secondary metabolites.
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39.发明授权公开(公告)号：US10966919B2
公开(公告)日：2021-04-06
申请号：US15996791
申请日：2018-06-04
Applicant: Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Lakshmi Mundkur , Shaheen Majeed
Inventor： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Lakshmi Mundkur , Shaheen Majeed
Abstract: Disclosed is the use of partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856 to prevent skin aging. More specifically the invention discloses the anti-collagenase, anti-elastase, anti-glycation activity and enhancement of TGF-β, epidermal growth factor and hyaluronic acid expression in human dermal fibroblasts, of extracellular metabolites isolated from Bacillus coagulans MTCC 5856.
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公开(公告)号：US20190264295A1
公开(公告)日：2019-08-29
申请号：US16281120
申请日：2019-02-21
Applicant: Muhammed Majeed , Kalyanam Nagabhushanam , Anju Majeed , Nooruddin Thajuddin , Sivakumar Arumugam , Krishnamurthy Kulithalai Viswanathan , Samuel Thomas Manoharan , Furqan Ali , John Adams Sebastian , Jamsheeda Moothedath , Muthuraman Gnanamani , Kirankumar Beede
Inventor： Muhammed Majeed , Kalyanam Nagabhushanam , Anju Majeed , Nooruddin Thajuddin , Sivakumar Arumugam , Krishnamurthy Kulithalai Viswanathan , Samuel Thomas Manoharan , Furqan Ali , John Adams Sebastian , Jamsheeda Moothedath , Muthuraman Gnanamani , Kirankumar Beede
IPC: C12R1/645 , A61K36/9066 , A61K31/216 , C12R1/38
Abstract: The present invention discloses a novel endophytic fungi, Ovatospora brasiliensis MTCC 25236 for the bioconversion of curcuminoids to Calebin-A and a method for its isolation from the rhizomes of Curcuma sp. The invention also discloses a method for the bioconversion of curcuminoids to Calebin-A using an endophytic fungi Ovatospora brasiliensis MTCC 25236 and bacterial species, Acinetobacter johnsonii and Pseudomonas putida.
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