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    Fiber-optic sensor for strain-insensitive temperature measurements
    31.
    发明授权
    Fiber-optic sensor for strain-insensitive temperature measurements 有权

    公开(公告)号：US09677949B1

    公开(公告)日：2017-06-13

    申请号：US14526168

    申请日：2014-10-28

    Applicant: The Board of Regents of the University of Nebraska

    Inventor： Ming Han

    IPC: G01K11/32 ,  G01K1/26 ,  G01K11/12 ,  G01J3/45

    CPC classification number: G01K11/3206 ,  G01J3/45 ,  G01J5/0821 ,  G01J5/602 ,  G01J2005/583 ,  G01K1/26 ,  G01K11/125

    Abstract: An in-line fiber-optic temperature sensor is disclosed. In an implementation, the in-line fiber-optic temperature sensor includes an optically transmissive fiber, a reflector, a microstructured fiber defining a channel therein for receiving a fluid, and a Fabry-Perot cavity in fluid communication with the microstructured fiber. The microstructured fiber can be retained between the optically transmissive fiber and the reflector. The Fabry-Perot cavity defined by a material and configured to receive a gas having an index of refraction that changes in a known way with temperature and pressure changes in fluid communication with the channel of the microstructured fiber. The in-line fiber-optic temperature sensor also includes a chamber defined between the optically transmissive fiber and the microstructured fiber for connecting in fluid communication with a vacuum/pressure source for changing pressure. The in-line fiber-optic temperature sensor also includes a sensor for determining an optical interferometric reflection spectrum associated with the Fabry-Perot cavity.

    INTUBATION GUIDE
    35.
    发明申请
    INTUBATION GUIDE 审中-公开

    公开(公告)号：US20130211263A1

    公开(公告)日：2013-08-15

    申请号：US13799775

    申请日：2013-03-13

    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA

    Inventor： Benje Boedeker

    IPC: A61M16/04 ,  A61B1/04 ,  A61B5/00 ,  A61B1/267

    CPC classification number: A61M16/0488 ,  A61M16/0418 ,  A61M16/0434

    Abstract: Apparatuses for guiding an endotracheal tube during intubation and associated methods of their use; the apparatuses formed to contain a plastic element able to hold deformations so as to conform the apparatus to the shape of a patient's endotracheal airway. The plastic element has sufficient give so as to minimize traumatic engagement with the inner surface of the airway lumen. Methods for using the apparatuses exploit indirect visualization where the person performing the intubation can shape the apparatuses so as to place the distal end into the field of view of the indirect visualization instrument even with minimal alignment of the patient's airway.

    Sulfur dye protection systems and compositions and methods employing same
    37.
    发明申请
    Sulfur dye protection systems and compositions and methods employing same 审中-公开
    硫化染料保护系统及其组合物和方法

    公开(公告)号：US20040194225A1

    公开(公告)日：2004-10-07

    申请号：US10821139

    申请日：2004-04-09

    Applicant: The Board of Regents of the University of Nebraska

    Inventor： Jiping Wang

    IPC: D06M010/00

    CPC classification number: C11D3/046 ,  C09B49/00 ,  C09B67/0077 ,  C11D3/168 ,  C11D3/40 ,  C11D7/10 ,  C11D17/041 ,  D06P1/30 ,  D06P1/67341 ,  D06P5/02 ,  Y10S8/918

    Abstract: The present invention relates to sulfur dye protection systems and compositions and methods employing same, as well as processes for making sulfur dyes, especially bleach stable sulfur dyes, processes for dying textiles with sulfur dyes and textiles dyed by such processes. More particularly, the present invention relates to modifying existing dyes and/or making newly formed sulfur dyes. Even more particularly, the present invention relates to materials that can chemically or physically interact with sulfur dyes to protect the sulfur dyes from oxidation by oxidizing agents, such as bleaching agents.

    Abstract translation: 本发明涉及硫化染料保护体系及其组合物和使用方法，以及制备硫化染料，特别是漂白稳定硫化染料的方法，用硫染料染色纺织品和通过这些方法染色的织物的方法。 更具体地说，本发明涉及改性现有染料和/或制备新形成的硫化染料。 更具体地说，本发明涉及能够与硫化染料进行化学或物理相互作用以保护硫化染料免受氧化剂如漂白剂氧化的材料。

    Microbubble compositions and methods for oligonucleotide delivery
    38.
    发明申请
    Microbubble compositions and methods for oligonucleotide delivery 有权
    微泡组合物和寡核苷酸递送方法

    公开(公告)号：US20040013662A1

    公开(公告)日：2004-01-22

    申请号：US10355388

    申请日：2003-01-31

    Applicant: The Board of Regents of the University of Nebraska

    Inventor： Thomas R. Porter ,  Patrick L. Iversen

    IPC: A61K038/47 ,  A61K038/42 ,  A61K038/38

    CPC classification number: A61K41/0028 ,  A61K47/6925 ,  A61K49/223

    Abstract: The invention relates to a new and improved pharmaceutical composition and method for delivery of therapeutic agents. The methods and composition of the invention can be used with several therapeutic agents and can achieve site specific delivery of a therapeutic or diagnostic substance. This can allow for lower doses and for improved efficacy with drugs which traditionally reach targeted sites and can result in improved utility for agents such as oligonucleotides and polynucleotides which are plagued with problems with biodistribution.

    Abstract translation: 本发明涉及用于递送治疗剂的新的和改进的药物组合物和方法。 本发明的方法和组合物可以与几种治疗剂一起使用，并且可以实现治疗或诊断物质的位点特异性递送。 这可以允许较低剂量和用于改善传统上达到目标部位的药物的功效，并且可以导致药物如寡核苷酸和多核苷酸的改善效用，这些药物被困扰生物分布的问题。

    Computer server having non-client-specific persistent connections
    40.
    发明申请
    Computer server having non-client-specific persistent connections 审中-公开
    具有非客户端特定持久连接的计算机服务器

    公开(公告)号：US20020055983A1

    公开(公告)日：2002-05-09

    申请号：US10008035

    申请日：2001-11-05

    Applicant: The Board of Regents of the University of Nebraska

    Inventor： Stephen M. Goddard

    IPC: G06F015/16

    CPC classification number: H04L29/06 ,  H04L67/1002 ,  H04L67/1008 ,  H04L67/2814 ,  H04L67/2819 ,  H04L67/2842 ,  H04L69/16 ,  H04L69/161 ,  H04L69/329 ,  H04L2029/06054

    Abstract: Standalone and cluster-based servers, including Web servers, control the amount of data processed concurrently by such servers to thereby control server operating performance. Each server preferably includes a dispatcher for receiving data requests from clients, and at least one back-end server for processing such requests. The dispatcher preferably maintains a persistent connection, or a set of persistent connections, with the back-end server, and forwards the data requests received from clients to the back-end server over the persistent connections. Thus, instead of maintaining a one-to-one mapping of back-end connections to front-end connections as is done in the prior art, the back-end connections can be maintained by the dispatcher and used repeatedly for sending data between the dispatcher and the back-end server. In this manner, back-end connection overhead is markedly reduced.

    Abstract translation: 独立和基于群集的服务器（包括Web服务器）控制这些服务器并发处理的数据量，从而控制服务器的运行性能。 每个服务器优选地包括用于从客户端接收数据请求的调度器和用于处理这些请求的至少一个后端服务器。 调度员优选地与后端服务器维护持久连接或一组持久连接，并且通过持久连接将从客户端接收的数据请求转发到后端服务器。 因此，不像现有技术那样维持后端连接到前端连接的一对一映射，而是可以由调度器维护后端连接，并重复使用以在调度器之间发送数据 和后端服务器。 以这种方式，后端连接开销显着降低。

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