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公开(公告)号：US20210337807A1
公开(公告)日：2021-11-04
申请号：US17416881
申请日：2019-12-20
IPC分类号： A01N65/00 , A61K8/9728 , A61Q17/00
摘要： The biologically active substance is obtained or capable of being obtained by alkaline extraction, using an aqueous solution of at least one base in the presence of at least one reducing agent, of at least one macroscopic edible mushroom reduced to powder, to obtain a mixture having a liquid portion containing the soluble extracted materials and a solid portion formed of insoluble solid particles; filtering the resulting mixture to remove the solid portion and optionally clarifying the liquid portion; neutralising the liquid portion using a cation exchange resin and optionally filtering/clarifying the liquid portion thus neutralised to obtain the biologically active substance in the aqueous phase; and treating the resulting aqueous phase, the treatment being selected from dilution in water, concentration, dehydration and lyophilisation to obtain a biologically active substance which is, respectively, more diluted in water, in an aqueous solution more concentrated, dehydrated in powder form or lyophilised.
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公开(公告)号：US11079589B2
公开(公告)日：2021-08-03
申请号：US16633831
申请日：2018-07-11
发明人： Abdel Fetah Benabid
摘要： An optical fibre for an ultrafast laser endoscope including at least the following structures: a hollow core, the periphery of which has an order of symmetry of at least six when considering axes of symmetry passing through the centre of the core and through the centre of convex shapes, seen from the centre of the core, the convex shapes at least partly making up the periphery of the core; an intermediate layer of cellular structure surrounding the core; a light conducting peripheral structure surrounding the intermediate layer of cellular structure; and an outer sheath surrounding the light-conducting peripheral structure. A particular advantage of the optical fibre is that it optimizes the emission of a high-power flux associated with fluorescence collection.
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公开(公告)号：US10965282B2
公开(公告)日：2021-03-30
申请号：US16490017
申请日：2018-02-27
申请人： THALES , COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES , UNIVERSITE DE LIMOGES
发明人： Olivier Jardel , Raymond Quere , Stéphane Piotrowicz , Philippe Bouysse , Sylvain Delage , Audrey Martin
IPC分类号： H03K17/687 , H02M3/156 , H03F3/19 , H03K19/094
摘要： A power switching cell, and associated multi-level converter, include an input port capable of receiving a switching control signal, an input transistor linked by the gate to the input port, and by the source to a reference voltage, a self-biasing circuit comprising a self-biasing transistor linked by the gate to the drain of the input transistor, and a resistor connected in parallel between the gate and the source of the self-biasing transistor, and in series between the drain of the input transistor and the source of the self-biasing transistor, a power transistor, linked by the gate to the source of the self-biasing transistor and by the drain to a power supply voltage, and an isolating transistor linked by the gate and by the source to the gate and to the source of the power transistor, and by the drain to the output port of the cell.
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公开(公告)号：US20200321166A1
公开(公告)日：2020-10-08
申请号：US16303639
申请日：2017-05-16
摘要： A radio frequency micro-electromechanical switch (generally referred to using the acronyms RF MEMS) is described. Also described is a method of producing such an RF MEMS switch.
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公开(公告)号：US10447002B2
公开(公告)日：2019-10-15
申请号：US15568876
申请日：2016-04-22
摘要： A monomode optical fiber, and a process for manufacturing such a fiber, that comprises a monomode core and at least one cladding encircling the core. The monomode core comprises at least two zones, a first zone with at least one first refractive index and a second zone with at least one second refractive index different from the first refractive index. The difference between the first refractive index and the second refractive index is of the same order of magnitude as the variation in the refractive index of the second zone between the inactive state and the active state of the fiber.
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公开(公告)号：US20190173256A1
公开(公告)日：2019-06-06
申请号：US16320993
申请日：2017-07-25
发明人： Sébastien FEVRIER , Leonid KOTOV , Ammar HIDEUR
摘要： A femtosecond laser source includes an injection laser oscillator with an optical fiber doped with a given material, suitable for delivering, via an output optical fiber, a first picosecond pulse, at a first wavelength λ1; a power amplifier with an amplifying optical fiber for producing, from the first pulse, a second pulse at the first wavelength, with an energy that is amplified relative to the first pulse, the amplifying optical fiber being doped with the same material as the optical fiber of the injection oscillator and having a length less than or equal to the distance from the point of soliton compression and greater than the distance from which the amplifying optical fiber operates in non-linear mode; a fiber with a frequency shift suitable for receiving the second pulse and generating, by Raman self-shifting, a fundamental soliton at a second wavelength λ2 that is strictly greater than the first wavelength λ1.
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37.发明申请公开(公告)号：US20190123506A1
公开(公告)日：2019-04-25
申请号：US16093120
申请日：2017-03-31
摘要： A generating device includes at least one pulsed laser source that delivers primary photons having at least one wavelength in a single spatial mode and in pulses having a high pump energy, forming means that act on the primary photons to deliver an input beam, and at least one optical fiber having at least ten modes between which the pump energy is initially distributed, and able to relocate the latter via a non-linear effect into a fundamental mode, before generating secondary photons of various wavelengths by wavelength conversions from the wavelength of the primary photons in the fundamental spatial mode.
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公开(公告)号：US20190056373A1
公开(公告)日：2019-02-21
申请号：US15770966
申请日：2016-10-27
申请人： UNIVERSITE DE LIMOGES , CNRS
发明人： Ameni Gharzouni , Laëticia Vidal , Sylvie Rossignol , Elodie Prud'Homme , Alexandre Autef , Emmanuel JOUSSEIN
摘要： A method for determination of the behavior of a reactive mixture intended for obtaining a geopolymer. The reactive mixture comprises at least one aluminosilicate material. The method includes determining a proportion of amorphous phase of the at least one aluminosilicate material and determining a degree of wettability of the at least one aluminosilicate material. If the proportion of amorphous phase is greater than 45% and if the degree of wettability is situated in a range between 300 μg/l and 1400 μg/l, then the reactive mixture, formed by the reaction of the at least one aluminosilicate material with an alkaline solution, forms a geopolymer.
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公开(公告)号：US20180364238A1
公开(公告)日：2018-12-20
申请号：US15780675
申请日：2016-12-02
IPC分类号： G01N33/574
摘要： The invention relates to the use of a lectin that recognizes the fucose α 1-2 galactose unit, as a means for labeling colorectal cancer stem cells, for the detection and/or quantification of said colorectal cancer stem cells, and the use of said lectin in a method for diagnosing the aggressiveness, recurrence risk and a prognostic value in order to adapt colorectal cancer treatment.
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公开(公告)号：US10038441B2
公开(公告)日：2018-07-31
申请号：US15306027
申请日：2015-04-17
申请人： THALES , COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES , UNIVERSITE DE LIMOGES , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人： Olivier Jardel , Raymond Quere , Stéphane Piotrowicz , Philippe Bouysse , Sylvain Delage , Audrey Martin
IPC分类号： H03B1/00 , H03K3/00 , H03K17/687 , H03K19/094 , H03K17/041
CPC分类号： H03K17/687 , H03K17/04106 , H03K19/09407
摘要： A power switching cell with normally on field-effect transistors comprises a current switch receiving the control input signal over an activation input and a power transistor for switching a high voltage VDD applied to its drain, to its source that is connected to the output port of the cell. The control of the gate of the power transistor whose source is floating, according to the input signal, is provided by a self-biasing circuit connected between its gate and source. The current switch is connected between the self-biasing circuit and a zero or negative reference voltage. The self-biasing circuit comprises a transistor whose source or drain is connected to the gate or source of the power transistor. The gate of this transistor is biased by a resistor connected between its gate and source, and between the current switch and the source. The transistors are HEMT transistors using GaN or AsGa technology.
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