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31.
公开(公告)号:US20240001004A1
公开(公告)日:2024-01-04
申请号:US18037684
申请日:2021-11-18
Applicant: University of Virginia Patent Foundation
Inventor: Steven R. Caliari , Ivan Basurto
CPC classification number: A61L27/56 , A61L27/3826 , A61L27/3834 , A61L27/26 , A61N1/05 , A61L2430/30
Abstract: A multicompartment conductive collagen scaffold composite, comprising a scaffold comprising collagen and an electrically conductive material, optionally wherein the electrically conductive material comprises electrically conductive particles, and further comprising longitudinally aligned pores, and methods of making and using the same.
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公开(公告)号:US11850448B2
公开(公告)日:2023-12-26
申请号:US18065727
申请日:2022-12-14
Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Inventor: Jeffrey Vincent Siebers , Mahmoud Ahmed
IPC: A61N5/10
CPC classification number: A61N5/1075 , A61N2005/1054 , G06T2207/10116
Abstract: An image calibration method includes capturing and correcting a flood field image for background signal and effects of known image-panel features (dead/bad pixels). The corrected image is processed to separate frequencies characteristic of relative pixel sensitivities from frequencies characteristic of radiation energy fluence. The incident energy fluence has a known maximum in-field energy fluence gradient. A model that describes the incident energy fluence on a detector is generated or received. The corrected image may be modeled at frequencies at or below the maximum in-field energy fluence gradient. A pixel sensitivity matrix (PSM) is generated by adjusting the corrected image with the model of the incident energy fluence on the detector. For example, the corrected image signal may be divided by the model or the model may be subtracted from the corrected image. The PSM may be used to correct additional raw images captured by the detector.
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公开(公告)号:US20230407788A1
公开(公告)日:2023-12-21
申请号:US17841281
申请日:2022-06-15
Inventor: Brian J. Connolly , Eric Loth , Crawford F. Smith, III
IPC: F02C7/052
CPC classification number: F02C7/052 , F05D2260/607
Abstract: An inlet duct for a gas turbine engine includes a particle separator, a scavenge duct, and a layer of material having a low coefficient of restitution. The particle separator including an outer wall spaced, an inner wall, and a splitter located radially between the outer wall and the inner wall. The scavenge duct is coupled with particle separator. The layer of material is located on at least one of the outer wall, the splitter, and the scavenge duct.
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公开(公告)号:US11846692B2
公开(公告)日:2023-12-19
申请号:US17733967
申请日:2022-04-29
Applicant: University of Virginia Patent Foundation
Inventor: Quan Dou , Zhixing Wang , Xue Feng , John P. Mugler, III , Craig H. Meyer
IPC: G01R33/56 , G01R33/565 , G06T7/262
CPC classification number: G01R33/5608 , G01R33/56509 , G06T7/262 , G06T2207/10088 , G06T2207/20084
Abstract: Training a neural network to correct motion-induced artifacts in magnetic resonance images includes acquiring motion-free magnetic resonance image (MRI) data of a target object and applying a spatial transformation matrix to the motion-free MRI data. Multiple frames of MRI data are produced having respective motion states. A Non-uniform Fast Fourier Transform (NUFFT) can be applied to generate respective k-space data sets corresponding to each of the multiple frames of MRI; the respective k-space data sets can be combined to produce a motion-corrupted k-space data set and an adjoint NUFFT can be applied to the motion-corrupted k-space data set. Updated frames of motion-corrupted MRI data can be formed. Using the updated frames of motion corrupted MRI data, a neural network can be trained that generates output frames of motion free MRI data; and the neural network can be saved.
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公开(公告)号:US20230390586A1
公开(公告)日:2023-12-07
申请号:US18453788
申请日:2023-08-22
Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Inventor: Jeffrey Vincent Siebers , Mahmoud Ahmed
IPC: A61N5/10
CPC classification number: A61N5/1075 , G06T2207/10116 , A61N2005/1054
Abstract: An image calibration method includes capturing and correcting a flood field image for background signal and effects of known image-panel features (dead/bad pixels). The corrected image is processed to separate frequencies characteristic of relative pixel sensitivities from frequencies characteristic of radiation energy fluence. The incident energy fluence has a known maximum in-field energy fluence gradient. A model that describes the incident energy fluence on a detector is generated or received. The corrected image may be modeled at frequencies at or below the maximum in-field energy fluence gradient. A pixel sensitivity matrix (PSM) is generated by adjusting the corrected image with the model of the incident energy fluence on the detector. For example, the corrected image signal may be divided by the model or the model may be subtracted from the corrected image. The PSM may be used to correct additional raw images captured by the detector.
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公开(公告)号:US11813024B2
公开(公告)日:2023-11-14
申请号:US17302123
申请日:2021-04-23
Applicant: University of Virginia Patent Foundation
Inventor: Paul Andrew Yates , Kenneth Tran
CPC classification number: A61B3/156 , A61B3/12 , A61B3/1208 , A61B3/14 , G06V40/19
Abstract: System and Method pertaining to the modification and integration of an existing consumer digital camera, for example, with an optical imaging module to enable point and shoot fundus photography of the eye. The auto-focus macro capability of existing consumer cameras is adapted to photograph the retina over an extended diopter range, eliminating the need for manual diopter focus adjustment. The thru-the-lens (TTL) auto-exposure flash capability of existing consumer cameras is adapted to photograph the retina with automatic flash exposure eliminating the need for manual flash adjustment. The consumer camera imaging sensor and flash are modified to allow the camera sensor to perform both non-mydriatic focusing of the retina using infrared illumination and standard color flash photography of the retina without the need for additional imaging sensors or mechanical filters. These modifications and integration of existing consumer cameras for fundus photography of the eye significantly improve ease of manufacture and usability.
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公开(公告)号:US20230352185A1
公开(公告)日:2023-11-02
申请号:US18041659
申请日:2021-08-13
Applicant: University of Virginia Patent Foundation
Inventor: Boris P. KOVATCHEV , Marc D. BRETON , Ke WANG , Patricio COLMEGNA
CPC classification number: G16H50/50 , G16H20/17 , G16H20/60 , A61B5/14532
Abstract: A method, system, and computer-readable medium are provided for modeling a time-varying representation of the glucose homeostasis of a patient with Type 1 diabetes (T1D) according to a computational model therefor. The model implements a reconstruction of data supporting a glucose time series for the patient, and based on the reconstruction, further implements model personalization and a variability control (VC) signal accounting for insulin sensitivity so as to enable the patient to learn an effect of adjustment to one or more portions of the data. Such knowledge is acquired upon a replay of the reconstruction implementing the adjustment.
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38.
公开(公告)号:US20230343373A1
公开(公告)日:2023-10-26
申请号:US18306531
申请日:2023-04-25
Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Inventor: KEVIN SKADRON , MARZIEH LENJANI
CPC classification number: G11C7/1039 , G11C7/1057 , G06F17/16
Abstract: An integrated circuit memory device can include a plurality of banks of memory, each of the banks of memory including a first pair of sub-arrays comprising first and second sub-arrays, the first pair of sub-arrays configured to store data in memory cells of the first pair of sub-arrays, a first row buffer memory circuit located in the integrated circuit memory device adjacent to the first pair of sub-arrays and configured to store first row data received from the first pair of sub-arrays and configured to transfer the row data into and/or out of the first row buffer memory circuit, and a first sub-array level processor circuit in the integrated circuit memory device adjacent to the first pair of sub-arrays and operatively coupled to the first row data, wherein the first sub-array level processor circuit is configured to perform column oriented processing a sparse matrix kernel stored, at least in-part, in the first pair of sub-arrays, with input vector values stored, at least in part, in the first pair of sub-arrays to provide output vector values representing products of values stored in columns of the sparse matrix kernel with the input vector values.
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公开(公告)号:US11776594B2
公开(公告)日:2023-10-03
申请号:US17462836
申请日:2021-08-31
Applicant: University of Virginia Patent Foundation
Inventor: Kevin Skadron , Marzieh Lenjani , Abdolrasoul Sharifi , Lingxi Wu
CPC classification number: G11C7/1087 , G11C7/106 , G11C7/12 , H03K19/20
Abstract: Apparatus includes a plurality of memory cells (e.g., a dynamic random access memory (DRAM)) addressable as rows and columns and a plurality of matching circuits configured to be coupled to respective bit lines associated with the columns A control circuit is configured to store respective reference sequences (e.g., binary-encoded k-mer patterns) in respective ones of the columns, to sequentially provide rows of bits stored in the memory cells and bits of a query to the matching circuits, and to identify one of the reference sequences as corresponding to the query responsive to comparisons by the matching circuits.
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公开(公告)号:US20230293062A1
公开(公告)日:2023-09-21
申请号:US18325564
申请日:2023-05-30
Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Inventor: Boris P. KOVATCHEV , Marc D. BRETON , Stephen D. PATEK
CPC classification number: A61B5/14532 , G16H50/50 , A61B5/746 , A61B5/4839 , A61B5/7275 , G16H20/17 , A61B5/0004 , A61M5/1723 , G16H40/63 , A61B5/0002 , G16H40/67
Abstract: An aspect of an embodiment or partial embodiment of the present invention (or combinations of various embodiments in whole or in part of the present invention) comprises, but not limited thereto, a method and system (and related computer program product) for continually assessing the risk of hypoglycemia for a patient and then determining what action to take based on that risk assessment. A further embodiment results in two outputs: (1) an attenuation factor to be applied to the insulin rate command sent to the pump (either via conventional therapy or via open or closed loop control) and/or (2) a red/yellow/green light hypoglycemia alarm providing to the patient an indication of the risk of hypoglycemia. The two outputs of the CPHS can be used in combination or individually.
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