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31.发明申请Method and system for determining channel response in a block transmission system 审中-公开用于确定块传输系统中的信道响应的方法和系统公开(公告)号：US20070217527A1
公开(公告)日：2007-09-20
申请号：US11481616
申请日：2006-07-06
CPC分类号： H04L25/022 , H04L25/0232 , H04L27/2601
摘要： A method and system for determining channel response is provided. The method for determining a channel frequency response (CFR) in a block transmission system comprises performing an N′ point Fast Fourier Transformation (FFT), where N′ is a function of N and K, and N is approximately equal to the number of sub-carriers in a block, and K depends on the coherence bandwidth of the channel corresponding to the block.
摘要翻译： 提供了一种用于确定信道响应的方法和系统。 用于确定块传输系统中的信道频率响应（CFR）的方法包括执行N'点快速傅里叶变换（FFT），其中N'是N和K的函数，并且N近似等于子数 - 块中的载波，并且K取决于对应于该块的信道的相干带宽。
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公开(公告)号：US20130130751A1
公开(公告)日：2013-05-23
申请号：US13309290
申请日：2011-12-01
申请人： Shashidhar Vummintala , Gowrisankar Somichetty , Sriram Rajagopal , Sindhu Verma , Manish Airy , Hariprasad Gangadharan , Pugazhanthi R.P. , Felix Varghese , Erik Stauffer
发明人： Shashidhar Vummintala , Gowrisankar Somichetty , Sriram Rajagopal , Sindhu Verma , Manish Airy , Hariprasad Gangadharan , Pugazhanthi R.P. , Felix Varghese , Erik Stauffer
IPC分类号： H04W52/02
CPC分类号： H04W52/0216 , H03D7/16 , H04L41/0803 , H04W28/0263 , Y02D70/00 , Y02D70/1262 , Y02D70/146 , Y02D70/164 , Y02D70/23 , Y02D70/24
摘要： A wireless communication device is disclosed that is capable of reduced power consumption. Uplink and downlink sub-frames in a WiMAX, 802.16m or LTE environment often include several vacant symbols during which power-hungry hardware and software components need not operate at full power. By analyzing a physical layer beacon and control information of a received signal, the specific locations of data bursts can be determined, as well as periods of needed operation of a receiver module to effectively decode those data bursts. The receiver module can otherwise be controlled to operate in a LOW power state during remaining periods of vacant time, thereby conserving power consumption and extending battery life.
摘要翻译： 公开了能够降低功耗的无线通信设备。 WiMAX，802.16m或LTE环境中的上行链路和下行链路子帧通常包括几个空闲符号，在此期间，功耗很大的硬件和软件组件不需要在全功率下运行。 通过分析接收信号的物理层信标和控制信息，可以确定数据突发的特定位置以及接收机模块有效解码这些数据脉冲串的所需操作周期。 否则，在空闲时间的剩余时间期间，接收器模块可以被控制为在低功率状态下操作，从而节省功耗并延长电池寿命。
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公开(公告)号：US07786142B2
公开(公告)日：2010-08-31
申请号：US11546299
申请日：2006-10-12
申请人： Siripragada Mahender Rao , Akella Satya Surya Visweswara Srinvas , Shikha Rani , Gaddam Om Reddy , Sriram Rajagopal , Uma Ramachandran , Duddu Savaraiah Sharada , Rajagopalan Nirmala , Velaiah Sivasudar , Lakshmanan Manikandan , Ramachandran Balaji
发明人： Siripragada Mahender Rao , Akella Satya Surya Visweswara Srinvas , Shikha Rani , Gaddam Om Reddy , Sriram Rajagopal , Uma Ramachandran , Duddu Savaraiah Sharada , Rajagopalan Nirmala , Velaiah Sivasudar , Lakshmanan Manikandan , Ramachandran Balaji
IPC分类号： A61K31/4468 , A61K31/403 , C07D405/14 , C07D209/88
CPC分类号： C07D209/88 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D417/12
摘要： The present invention relates to novel heterocyclic compounds of the general formula (I), as IL-6 inhibitors, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts and compositions, their metabolites and prodrugs thereof. The present invention more particularly provides novel heterocyclic compounds of the general formula (I). Also included is a method for treatment of cancer, cancer cachexia and inflammatory diseases including immunological diseases, particularly those mediated by cytokines such as IL-6, through pSTAT3 inhibition, in a mammal comprising administering an effective amount of a compound of formula (I) as described above
摘要翻译： 本发明涉及通式（I）的新型杂环化合物，作为IL-6抑制剂，其衍生物，其类似物，其互变异构形式，其立体异构体，其多晶型物，其水合物，其溶剂合物，其药学上可接受的盐和组合物 ，它们的代谢物和前药。 本发明更具体地提供了通式（I）的新型杂环化合物。 还包括在哺乳动物中治疗癌症，癌症恶病质和炎性疾病的方法，包括免疫疾病，特别是通过pSTAT3抑制的细胞因子如IL-6介导的疾病，包括给予有效量的式（I）化合物， 如上所述
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公开(公告)号：US07687488B2
公开(公告)日：2010-03-30
申请号：US11822956
申请日：2007-07-11
申请人： Senthilkumar Udayampalayam Palanisamy , Andrew Gnanaprakasam , Panchapakesan Ganapathy , Mukut Gohain , Venkatasubramanian Hariharan , Sriram Rajagopal , Maneesh Paul-Satyaseela , Shakti Singh Solanki , Sathishkumar Devarajan
发明人： Senthilkumar Udayampalayam Palanisamy , Andrew Gnanaprakasam , Panchapakesan Ganapathy , Mukut Gohain , Venkatasubramanian Hariharan , Sriram Rajagopal , Maneesh Paul-Satyaseela , Shakti Singh Solanki , Sathishkumar Devarajan
IPC分类号： A61K31/43 , C07D499/00
CPC分类号： C07D499/86 , Y02P20/55
摘要： Novel 2-substituted methyl penam derivatives include the formula (I), their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their solvates, their pharmaceutically acceptable salts, and pharmaceutical compositions containing them; wherein A=C or N; Het is a three- to seven-membered heterocyclic ring; R1 represents carboxylate anion, or —COOR4 where R4 represents hydrogen, carboxylic acid protecting group or a pharmaceutically acceptable salt; R2 and R3 may be same or different and independently represent hydrogen, halogen, amino, alkyl, protected amino, optionally substituted alkyl, alkenyl, alkynyl and the like; R represents substituted or unsubstituted alkyl, alkenyl, aryl, aralkyl, cycloalkyl, heterocyclyl or heterocyclylalkyl.
摘要翻译： 新的2-取代的甲基penam衍生物包括式（I），它们的类似物，它们的互变异构形式，它们的立体异构体，它们的多晶型物，它们的溶剂合物，其药学上可接受的盐和含有它们的药物组合物; 其中A = C或N; Het是一个三至七元的杂环; R1表示羧酸根阴离子，或-COOR4，其中R4表示氢，羧酸保护基或药学上可接受的盐; R2和R3可以相同或不同，并且独立地表示氢，卤素，氨基，烷基，保护的氨基，任选取代的烷基，烯基，炔基等; R代表取代或未取代的烷基，烯基，芳基，芳烷基，环烷基，杂环基或杂环基烷基。
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公开(公告)号：US20080015156A1
公开(公告)日：2008-01-17
申请号：US11822956
申请日：2007-07-11
申请人： Senthilkumar Udayampalayam Palanisamy , Andrew Gnanaprakasam , Panchapakesan Ganapathy , Mukut Gohain , Venkatasubramanian Hariharan , Sriram Rajagopal , Maneesh Paul-Satyaseela , Shakti Solanki , Sathishkumar Devarajan
发明人： Senthilkumar Udayampalayam Palanisamy , Andrew Gnanaprakasam , Panchapakesan Ganapathy , Mukut Gohain , Venkatasubramanian Hariharan , Sriram Rajagopal , Maneesh Paul-Satyaseela , Shakti Solanki , Sathishkumar Devarajan
IPC分类号： A61K31/431 , A61K31/7036 , A61P31/00 , C07D499/00
CPC分类号： C07D499/86 , Y02P20/55
摘要： Novel 2-substituted methyl penam derivatives include the formula (I), their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their solvates, their pharmaceutically acceptable salts, and pharmaceutical compositions containing them; wherein A=C or N; Het is a three- to seven-membered heterocyclic ring; R1 represents carboxylate anion, or —COOR4 where R4 represents hydrogen, carboxylic acid protecting group or a pharmaceutically acceptable salt; R2 and R3 may be same or different and independently represent hydrogen, halogen, amino, alkyl, protected amino, optionally substituted alkyl, alkenyl, alkynyl and the like; R represents substituted or unsubstituted alkyl, alkenyl, aryl, aralkyl, cycloalkyl, heterocyclyl or heterocyclylalkyl.
摘要翻译： 新的2-取代的甲基penam衍生物包括式（I），它们的类似物，它们的互变异构形式，它们的立体异构体，它们的多晶型物，它们的溶剂合物，其药学上可接受的盐和含有它们的药物组合物; 其中A = C或N; Het是一个三至七元的杂环; R 1表示羧酸根阴离子或-COOR 4，其中R 4表示氢，羧酸保护基或其药学上可接受的盐; R 2和R 3可以相同或不同，并且独立地表示氢，卤素，氨基，烷基，保护的氨基，任选取代的烷基，烯基，炔基等; R代表取代或未取代的烷基，烯基，芳基，芳烷基，环烷基，杂环基或杂环基烷基。
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公开(公告)号：US06576662B2
公开(公告)日：2003-06-10
申请号：US09849584
申请日：2001-05-04
IPC分类号： A61K3134
CPC分类号： C07D405/06 , C07D307/58 , C07D405/08 , C07D405/12 , C07D417/12
摘要： The present invention relates to novel anticancer agents, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, and their pharmaceutically acceptable solvates. The present invention more particularly relates to novel derivatives of andrographolide, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, and their pharmaceutically acceptable solvates. The novel derivatives of andrographolide have the general formula (I).
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公开(公告)号：US10285655B2
公开(公告)日：2019-05-14
申请号：US14002787
申请日：2012-03-09
申请人： Shufang Dong , Terrance Joseph Nemenz , Patrick Cumpson , Jeremy David Pettinato , Sriram Rajagopal
发明人： Shufang Dong , Terrance Joseph Nemenz , Patrick Cumpson , Jeremy David Pettinato , Sriram Rajagopal
摘要： A method includes receiving a subject support motion disable signal indicative of at least one of power removal of an imaging system, a collision of a horizontally moving tabletop of the imaging system, a decoupling of a horizontal motion drive system configured to horizontally drive the tabletop, or a collision of a vertically moving subject support of the imaging system, wherein a vertical motion drive system drives the subject support vertical motion, and disabling, in response to receiving the subject support motion disable signal, at least one of tabletop horizontal motion or subject support vertical motion.
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公开(公告)号：US08856609B2
公开(公告)日：2014-10-07
申请号：US13434552
申请日：2012-03-29
申请人： Shashidhar Vummintala , Arumugam Velayoudame , Gowrisankar Somichetty , Sriram Rajagopal , Sandip Solanki , Kalyana Krishnan
发明人： Shashidhar Vummintala , Arumugam Velayoudame , Gowrisankar Somichetty , Sriram Rajagopal , Sandip Solanki , Kalyana Krishnan
CPC分类号： H03M13/091 , G06F11/10 , H03M13/09 , H03M13/1515 , H03M13/23 , H03M13/29 , H03M13/2906 , H03M13/2957 , H03M13/6306 , H04L1/0045 , H04L1/0052 , H04L1/0061 , H04L1/1809
摘要： Improved strategies for a Cyclical Redundancy Check (CRC) are disclosed. A CRC check of a codeblock may be initiated by a CRC decoder before receiving all of the bits by a corresponding FEC encoder. Furthermore, an incremental CRC check with respect to the data packet without the need for requesting passed through data from higher layers.
摘要翻译： 公开了循环冗余校验（CRC）的改进策略。 在通过相应的FEC编码器接收所有比特之前，可以由CRC解码器发起码块的CRC校验。 此外，相对于数据分组的增量CRC校验，而不需要请求通过来自较高层的数据。
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公开(公告)号：US20130132796A1
公开(公告)日：2013-05-23
申请号：US13434552
申请日：2012-03-29
申请人： Shashidhar VUMMINTALA , Arumugam Velayoudame , Gowrisankar Somichetty , Sriram Rajagopal , Sandip Solanki , Kalyana Krishnan
发明人： Shashidhar VUMMINTALA , Arumugam Velayoudame , Gowrisankar Somichetty , Sriram Rajagopal , Sandip Solanki , Kalyana Krishnan
CPC分类号： H03M13/091 , G06F11/10 , H03M13/09 , H03M13/1515 , H03M13/23 , H03M13/29 , H03M13/2906 , H03M13/2957 , H03M13/6306 , H04L1/0045 , H04L1/0052 , H04L1/0061 , H04L1/1809
摘要： The disclosure relates generally to the field of communications in transceiver, and more particularly to improved strategies for Cyclical Redundancy Check (CRC). A CRC check of a codeblock may be initiated by a CRC decoder before receiving all of the bits by a corresponding FEC encoder. Furthermore, an incremental CRC check with respect to the data packet without the need for requesting passed through data from higher layers.
摘要翻译： 本公开一般涉及收发器中的通信领域，更具体地涉及用于循环冗余校验（CRC）的改进策略。 在通过相应的FEC编码器接收所有比特之前，可以由CRC解码器发起码块的CRC校验。 此外，相对于数据分组的增量CRC校验，而不需要请求通过来自较高层的数据。
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40.发明授权5(S)-(2′-hydroxyethoxy)-20(S)-camptothecin and its preparation and use for the treatment of cancer 失效5（S） - （2'-羟基乙氧基）-20（S） - 喜树碱及其制备及用于治疗癌症公开(公告)号：US08080559B2
公开(公告)日：2011-12-20
申请号：US12577399
申请日：2009-10-12
申请人： Venkateswarlu Akella , Shanavas Alikunju , Ajaya Kumar Reka , Ramesh Mullangi , Raju Sirisilla , Subrahmanyam Duvvuri , Sriram Rajagopal
发明人： Venkateswarlu Akella , Shanavas Alikunju , Ajaya Kumar Reka , Ramesh Mullangi , Raju Sirisilla , Subrahmanyam Duvvuri , Sriram Rajagopal
IPC分类号： A61K31/4745 , C07D491/22
CPC分类号： C07D491/22 , C07D519/00
摘要： A 5(S)-(2′-hydroxyethoxy)-20(S)-camptothecin diasterisomer is described which is a better inhibitor of topoisomerase I than either the diastereoisomeric mixture 5(RS)-(2′-hydroxyethoxy)-20(S)-camptothecin, or the 5(R)-(2′-hydroxyethoxy)-20(S)-camptothecin diastereoisomer. Pharmaceutical compositions of the 5(S)-(2′-hydroxyethoxy)-20(S)-camptothecin diastereoisomer are also described as are methods of using the compound for the inhibition of topoisomerase I and for the treatment of cancer.
摘要翻译： 描述了5（S） - （2'-羟基乙氧基）-20（S） - 喜树碱非对映异构体，其是非对映异构体混合物5（RS） - （2'-羟基乙氧基）-20（S ） - 喜树碱或5（R） - （2'-羟基乙氧基）-20（S） - 喜树碱非对映异构体。 还描述了5（S） - （2'-羟基乙氧基）-20（S） - 喜树碱非对映异构体的药物组合物是使用该化合物抑制拓扑异构酶I和治疗癌症的方法。
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