公开(公告)号：US10765781B2

公开(公告)日：2020-09-08

申请号：US15642968

申请日：2017-07-06

Applicant: ARSENAL MEDICAL, INC.

Inventor： Upma Sharma ,  Irina Gitlin ,  Gregory T. Zugates ,  Adam Rago ,  Parisa Zamiri ,  Rany Busold ,  Toby Freyman ,  Robert J. Caulkins ,  Quynh P Pham ,  Changcheng You ,  Jeffrey D. Carbeck

IPC: A61L31/06 ,  A61J1/20 ,  A61L27/18 ,  A61L27/56 ,  A61L27/58 ,  A61L31/14 ,  A61M37/00 ,  A61B17/12 ,  C08L63/00

Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).

公开(公告)号：US10307515B2

公开(公告)日：2019-06-04

申请号：US14928857

申请日：2015-10-30

Applicant: ARSENAL MEDICAL, INC.

Inventor： Upma Sharma ,  Irina Gitlin ,  Gregory T. Zugates ,  Adam Rago ,  Parisa Zamiri ,  Rany Busold ,  Robert J. Caulkins ,  Toby Freyman ,  Quynh Pham ,  Changcheng You ,  Jeffrey Carbeck

IPC: A61F2/02 ,  A61L31/06 ,  A61J1/20 ,  A61L27/18 ,  A61L27/56 ,  A61L27/58 ,  A61L31/14 ,  A61M37/00 ,  A61B17/12 ,  C08L63/00

Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).

公开(公告)号：US20180140740A1

公开(公告)日：2018-05-24

申请号：US15355397

申请日：2016-11-18

Applicant: ARSENAL MEDICAL, INC.

Inventor： Adam Rago ,  John Marini ,  Gregory T. Zugates ,  Marc Helmick ,  Upma Sharma

IPC: A61L24/00 ,  A61L24/06

CPC classification number: A61L24/0036 ,  A61L24/06

Abstract: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.

公开(公告)号：US09883865B2

公开(公告)日：2018-02-06

申请号：US14728393

申请日：2015-06-02

Applicant: ARSENAL MEDICAL, INC.

Inventor： Toby Freyman ,  Joseph Lomakin ,  John Marini ,  Jennifer Mortensen ,  Adam Rago ,  Rany Busold ,  Upma Sharma ,  Gregory T. Zugates

IPC: A61F2/06 ,  A61B17/12 ,  A61M37/00 ,  A61L31/06 ,  A61L31/12 ,  A61L31/14 ,  A61L24/00 ,  A61L24/04 ,  A61F2/07 ,  A61J1/20

CPC classification number: A61B17/12181 ,  A61B17/12113 ,  A61B17/12118 ,  A61B17/1214 ,  A61B2017/1205 ,  A61F2/07 ,  A61F2002/065 ,  A61F2002/077 ,  A61F2210/0085 ,  A61J1/2093 ,  A61L24/0036 ,  A61L24/0089 ,  A61L24/046 ,  A61L31/06 ,  A61L31/128 ,  A61L31/146 ,  A61L2300/60 ,  A61L2400/06 ,  A61M37/00 ,  C08L67/04 ,  C08L83/04

Abstract: Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms or fluid filled spaces are disclosed. The systems include an insertable medical device and an in-situ forming foam of lava like materials with a fast forming outer skin and a slower hardening interior that is formed from a one-, two- or multi-part formulation. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.

公开(公告)号：US20240342338A1

公开(公告)日：2024-10-17

申请号：US18756670

申请日：2024-06-27

Applicant: Arsenal Medical, Inc.

Inventor： Jeffrey Groom ,  Craig Wiltsey ,  Quynh Pham ,  Nikhita Mansukhani ,  Courtney Guertin ,  Lee Core ,  Upma Sharma

IPC: A61L24/06 ,  A61K47/02 ,  A61K47/34 ,  A61K49/04 ,  A61L24/00 ,  A61L24/02 ,  A61L24/04 ,  C08L83/04

CPC classification number: A61L24/06 ,  A61K47/02 ,  A61K47/34 ,  A61K49/04 ,  A61K49/0409 ,  A61L24/0021 ,  A61L24/02 ,  A61L24/043 ,  A61L24/046 ,  C08L83/04 ,  A61L2400/06 ,  A61L2430/36

Abstract: The present disclosure pertains to crosslinkable compositions and systems as well as methods for forming crosslinked compositions in situ, including the use of the same for embolizing vasculature including the neurovasculature within a patient, among many other uses.

公开(公告)号：US20230414840A1

公开(公告)日：2023-12-28

申请号：US18465782

申请日：2023-09-12

Applicant: Arsenal Medical, Inc.

Inventor： Upma Sharma ,  Irina Gitlin ,  Gregory T. Zugates ,  Adam Rago ,  Parisa Zamiri ,  Rany Busold ,  Robert J. Caulkins ,  Toby Freyman ,  Quynh Pham ,  Changcheng You ,  Jeffrey Carbeck

IPC: A61L31/06 ,  A61J1/20 ,  A61L27/18 ,  A61L27/56 ,  A61L27/58 ,  A61L31/14 ,  A61M37/00 ,  A61B17/12 ,  C08L63/00

CPC classification number: A61L31/06 ,  A61J1/2093 ,  A61L27/18 ,  A61L27/56 ,  A61L27/58 ,  A61L31/148 ,  A61L31/146 ,  A61M37/00 ,  A61B17/12031 ,  A61B17/12163 ,  A61B17/12186 ,  A61L31/141 ,  C08L63/00 ,  A61L2400/04 ,  A61L2400/06 ,  A61B2017/12004 ,  A61L2400/18

Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).

公开(公告)号：US11844870B2

公开(公告)日：2023-12-19

申请号：US18322852

申请日：2023-05-24

Applicant: Arsenal Medical, Inc.

Inventor： Jeffrey Groom ,  Craig Wiltsey ,  Quynh Pham ,  Nikhita Mansukhani ,  Courtney Guertin ,  Lee Core ,  Upma Sharma

IPC: A61L24/04 ,  A61L24/02 ,  C08L83/04

CPC classification number: A61L24/043 ,  A61L24/02 ,  C08L83/04 ,  A61L2400/06 ,  A61L2430/36

Abstract: The present disclosure pertains to crosslinkable compositions and systems as well as methods for forming crosslinked compositions in situ, including the use of the same for embolizing vasculature including the neurovasculature within a patient, among many other uses.

公开(公告)号：US11246964B2

公开(公告)日：2022-02-15

申请号：US16376087

申请日：2019-04-05

Applicant: ARSENAL MEDICAL, INC.

Inventor： Upma Sharma ,  Irina Gitlin ,  Gregory T. Zugates ,  Adam Rago ,  Parisa Zamiri ,  Rany Busold ,  Robert J. Caulkins ,  Toby Freyman ,  Quynh Pham ,  Changcheng You ,  Jeffrey Carbeck

IPC: A61L27/56 ,  A61L31/06 ,  A61J1/20 ,  A61L27/18 ,  A61L27/58 ,  A61L31/14 ,  A61M37/00 ,  A61B17/12 ,  C08L63/00

Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).

公开(公告)号：US20210379207A1

公开(公告)日：2021-12-09

申请号：US17342945

申请日：2021-06-09

Applicant: Arsenal Medical, Inc.

Inventor： Jeffrey Groom ,  Craig Wiltsey ,  Quynh Pham ,  Nikhita Mansukhani ,  Courtney Guertin ,  Lee Core ,  Upma Sharma

IPC: A61K49/04 ,  A61K47/34 ,  A61K47/02 ,  A61L24/04 ,  A61L24/02

Abstract: The present disclosure pertains to crosslinkable compositions and systems as well as methods for forming crosslinked compositions in situ, including the use of the same for embolizing vasculature including the neurovasculature within a patient, among many other uses.

公开(公告)号：US10687795B2

公开(公告)日：2020-06-23

申请号：US15411505

申请日：2017-01-20

Applicant: Arsenal Medical, Inc.

Inventor： Upma Sharma ,  Rany Busold ,  Adam Rago ,  Gregory T. Zugates ,  Toby Freyman ,  Lisette Manrique Miller

IPC: A61F2/02 ,  A61B17/00 ,  B05B7/24 ,  B01F5/06 ,  B01F7/00 ,  B01F13/00 ,  B01F15/00 ,  B01F15/02 ,  B05C17/005 ,  B01F3/04 ,  A61C9/00 ,  A61M5/14 ,  A61M5/145 ,  A61M5/168 ,  B05B7/00 ,  A61M13/00 ,  A61M5/19 ,  B65D81/32 ,  A61B17/88

Abstract: Delivery systems for in situ forming foam formulations are provided. The devices may include various actuation mechanisms and may entrain air into fluid formulation components in a variety of ways, including mixing with air and the addition of compressed gas.