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79 条记录 (耗时 0.028 秒)

    Capillary electrophoresis device
    37.
    发明授权
    Capillary electrophoresis device 有权
    毛细管电泳装置

    公开(公告)号：US07081191B2

    公开(公告)日：2006-07-25

    申请号：US10239308

    申请日：2002-01-18

    申请人： Tomihiro Shoji ,  Masaya Kojima ,  Yoshiyuki Okishima ,  Ryoji Inaba

    发明人： Tomihiro Shoji ,  Masaya Kojima ,  Yoshiyuki Okishima ,  Ryoji Inaba

    IPC分类号： G01N27/447 ,  G01N27/953

    CPC分类号： G01N27/44769 ,  G01N27/447

    摘要： The capillary electrophoresis device using one pressure-resistant syringe (125) is capable of automatically suctioning in polymer solution and injecting polymer solution into a capillary array (100). An electric hook (131) is installed for pulling up the syringe plunger on a push-in action type syringe (125). A check valve (124) is inserted between a polymer bottle (123) and syringe to prevent solution from flowing back into the polymer bottle. As a result, one syringe portion of polymer solution can be suctioned and injected, a large volume of polymer solution can be continuously used and device processing capability is improved.

    摘要翻译： 使用一个耐压注射器（125）的毛细管电泳装置能够在聚合物溶液中自动抽吸并将聚合物溶液注入毛细管阵列（100）中。 安装电钩（131）以将注射器柱塞提升在推入式注射器（125）上。 将止回阀（124）插入聚合物瓶（123）和注射器之间以防止溶液流回到聚合物瓶中。 结果，可以吸引和注入聚合物溶液的一个注射器部分，可以连续使用大量的聚合物溶液，并且提高装置处理能力。

    Capillary electrophoresis apparatus and electrophoresis method
    38.
    发明授权
    Capillary electrophoresis apparatus and electrophoresis method 有权
    毛细管电泳仪和电泳法

    公开(公告)号：US08012327B2

    公开(公告)日：2011-09-06

    申请号：US11653332

    申请日：2007-01-16

    申请人： Motohiro Yamazaki ,  Ryoji Inaba ,  Satoshi Takahashi ,  Isao Haraura ,  Tomoyuki Sakai

    发明人： Motohiro Yamazaki ,  Ryoji Inaba ,  Satoshi Takahashi ,  Isao Haraura ,  Tomoyuki Sakai

    IPC分类号： G01N27/447

    CPC分类号： G01N27/44704 ,  G01N27/44721

    摘要： An object of the present invention is to provide a capillary electrophoresis apparatus in which simultaneity can be ensured between sensitivity and data acquisition to decrease a pull-up signal while spectral data acquisition is eliminated in each capillary exchange. The invention relates to a capillary electrophoresis apparatus in which capillary position shift is detected in each capillary exchange by detecting a capillary position. A capillary position measuring light source is provided in the capillary electrophoresis apparatus of the invention. The capillary is irradiated with light emitted from the capillary position measuring light source, a capillary image is detected with a two-dimensional detector, and thereby a position deviation of the capillary is determined. On the basis of the position deviation of the capillary, a data acquisition area is set in the two-dimensional detector, or a reference fluorescent light spectrum determined from the capillary at the standard position is corrected.

    摘要翻译： 本发明的目的是提供一种毛细管电泳装置，其中在每个毛细管交换中消除光谱数据采集时，可以在灵敏度和数据采集之间确保同时性，以减小上拉信号。 本发明涉及一种毛细管电泳装置，其中通过检测毛细管位置在每个毛细管交换中检测毛细管位置偏移。 在本发明的毛细管电泳装置中设置毛细管位置测定光源。 用从毛细管位置测量光源发射的光照射毛细管，用二维检测器检测毛细管图像，从而确定毛细管的位置偏差。 基于毛细管的位置偏差，在二维检测器中设置数据获取区域，或者校正从标准位置处的毛细管确定的参考荧光光谱。

    Capillary electrophoresis apparatus
    39.
    发明授权
    Capillary electrophoresis apparatus 有权
    毛细管电泳仪

    公开(公告)号：US07883613B2

    公开(公告)日：2011-02-08

    申请号：US11806889

    申请日：2007-06-05

    申请人： Takashi Gomi ,  Ryoji Inaba ,  Motohiro Yamazaki ,  Hidenori Namba ,  Jin Matsumura ,  Hiromi Yamashita ,  Seiichi Ugai ,  Kazumichi Imai

    发明人： Takashi Gomi ,  Ryoji Inaba ,  Motohiro Yamazaki ,  Hidenori Namba ,  Jin Matsumura ,  Hiromi Yamashita ,  Seiichi Ugai ,  Kazumichi Imai

    IPC分类号： G01N27/453

    CPC分类号： G01N27/44721

    摘要： The present invention provides a capillary electrophoresis apparatus in which a capillary is easily attached to and detached from a migration medium filling unit without mixing impurities into the capillary. Mixture of impurities such as dust is also prevented when a capillary negative-electrode end is brought into contact with a sample stored in a vessel. Furthermore, temperature control is efficiently performed in the capillary. In the capillary electrophoresis apparatus, the whole of capillary array can be supported by grasping a grip portion by hand. A migration medium filling mechanism includes a slide mechanism which moves a polymer block with respect to a capillary head. The capillary electrophoresis apparatus includes a vessel in which a sample and a buffer can simultaneously be stored. Temperatures of the capillary and an irradiation and detection unit are controlled by a temperature control function provided in a thermostatic device.

    摘要翻译： 本发明提供了一种毛细管电泳装置，其中毛细管容易地连接到迁移介质填充单元并从迁移介质填充单元中分离而不将杂质混入毛细管中。 当毛细管负极端与存储在容器中的样品接触时，也可以防止诸如灰尘等杂质的混合物。 此外，在毛细管中有效地进行温度控制。 在毛细管电泳装置中，通过用手抓握把手部分可以支撑整个毛细管阵列。 迁移介质填充机构包括相对于毛细管头移动聚合物嵌段的滑动机构。 毛细管电泳装置包括可以同时存储样品和缓冲液的容器。 毛细管和照射和检测单元的温度由恒温装置中提供的温度控制功能控制。

    ELECTROPHORESIS DEVICE
    40.
    发明申请
    ELECTROPHORESIS DEVICE 审中-公开
    电泳装置

    公开(公告)号：US20090255814A1

    公开(公告)日：2009-10-15

    申请号：US12420289

    申请日：2009-04-08

    申请人： Motohiro Yamazaki ,  Ryoji Inaba ,  Satoshi Takahashi

    发明人： Motohiro Yamazaki ,  Ryoji Inaba ,  Satoshi Takahashi

    IPC分类号： C25B9/00

    CPC分类号： G01N27/44721

    摘要： The invention aims to improve the spatial resolution in a multi-focus type electrophoresis apparatus that irradiates a capillary array from both ends thereof with laser beams. The invention relates to an electrophoresis apparatus in which capillaries at both ends of a capillary array are irradiated respectively with laser beams, and each of the two laser beams traverses multiple capillaries. In the electrophoresis apparatus, the laser beams are coaxially introduced into the capillary array from the both ends thereof to travel in a direction vertical to axis of each capillary and horizontal to the aligrnent plane of the capillary array; and a λ/4 plate and a polarizer are arranged on the laser beam optical axes. According to the invention, the total width of the incident laser beams is made narrow, generation of pseudo signals is prevented, and an analysis performance is improved.

    摘要翻译： 本发明旨在提高从其两端用激光束照射毛细管阵列的多焦点型电泳装置中的空间分辨率。 本发明涉及一种电泳装置，其中毛细管阵列的两端的毛细管分别照射激光束，并且两个激光束中的每一个穿过多个毛细管。 在电泳装置中，激光束从其两端同轴地引入到毛细管阵列中，以沿垂直于每个毛细管的轴线的方向行进，并且横向于毛细管阵列的致密平面; 并且在激光束光轴上设置λ/ 4板和偏振片。 根据本发明，使入射激光束的总宽度变窄，防止伪信号的产生，提高分析性能。