公开(公告)号：US09375574B2

公开(公告)日：2016-06-28

申请号：US14279415

申请日：2014-05-16

Applicant: Greatbatch Ltd.

Inventor： Norbert Kaula ,  Yohannes Iyassu

IPC: A61N1/36 ,  A61N1/372 ,  G06F19/00

CPC classification number: A61N1/36071 ,  A61N1/36132 ,  A61N1/36185 ,  A61N1/37247 ,  G06F19/00 ,  G06F19/3481 ,  G16H40/63

Abstract: A computer assisted programming method includes ramping up a stimulation current for a plurality of contacts on a lead. Patient feedback is received while the stimulation current is being ramped up. Patient feedback indicates that the patient is beginning to feel stimulation. Based on the patient feedback, amplitude of the stimulation current that resulted in the patient feedback is recorded, and contacts are divided into groups. The contacts are activated one group at a time to the recorded amplitude. For each activated group of contacts, whether the patient can feel stimulation is determined. Thereafter, the target group that caused the patient to feel stimulation is then sub-divided into sub-groups. This process repeats a plurality of cycles until one or more contacts that caused the patient to feel stimulation are identified. The recorded amplitude is assigned as a perception threshold for the identified one or more contacts.

Abstract translation: 计算机辅助编程方法包括增加引线上的多个触点的刺激电流。 当刺激电流正在上升时，接收到患者反馈。 患者反馈表明患者开始感觉到刺激。 根据患者反馈，记录导致患者反馈的刺激电流的幅度，并将接触分成组。 触点一次被激活到记录的幅度。 对于每个激活的接触组，确定患者是否感觉到刺激。 此后，导致患者感觉到刺激的目标群体然后被分为亚组。 该过程重复多个周期，直到导致患者感觉到刺激的一个或多个接触被识别。 记录的幅度被分配为所识别的一个或多个触点的感知阈值。

公开(公告)号：US09234920B2

公开(公告)日：2016-01-12

申请号：US14451830

申请日：2014-08-05

Applicant: Greatbatch Ltd.

Inventor： Norbert Kaula ,  Jeff A. Weisgarber ,  Yohannes Iyassu

IPC: A61N1/04 ,  G01R19/25 ,  A61N1/08 ,  A61N1/05

CPC classification number: G01R19/2503 ,  A61N1/025 ,  A61N1/04 ,  A61N1/0488 ,  A61N1/05 ,  A61N1/08 ,  A61N1/3752

Abstract: An electrically identifiable medical electrode lead. The lead includes a flexible lead body having a distal end and a connector end. The lead also includes a plurality of electrodes disposed near the distal end of the flexible lead body. The lead further includes a connector disposed at the connector end of the flexible lead body, the connector including a plurality of contacts. The lead additionally includes a plurality of conductors supported by and passing through the flexible lead body, the plurality of conductors including electrical conductors that provide paths for electrical current from the connector to the plurality of electrodes. Finally, the lead includes a memory circuit supported by the flexible lead body and being in electrical communication with a contact of the plurality of contacts in the connector.

Abstract translation: 电可识别的医用电极引线。 引线包括具有远端和连接器端的柔性引线体。 引线还包括设置在柔性引线主体的远端附近的多个电极。 引线还包括设置在柔性引线主体的连接器端处的连接器，该连接器包括多个触点。 引线还包括由柔性引线主体支撑并穿过柔性引线主体的多个导体，所述多个导体包括提供用于从连接器到多个电极的电流的路径的电导体。 最后，引线包括由柔性引线体支撑并与连接器中的多个触点的触点电连通的存储器电路。

公开(公告)号：US20150328463A1

公开(公告)日：2015-11-19

申请号：US14810758

申请日：2015-07-28

Applicant: Greatbatch Ltd.

Inventor： Norbert Kaula ,  Yohannes Iyassu

IPC: A61N1/36

CPC classification number: A61N1/36071 ,  A61N1/36132

Abstract: A patient feedback device for use in an electrical stimulation system is calibrated. The electrical stimulation system includes an implantable pulse generator (IPG) implanted in a patient and a patient feedback device having a force sensor. Input from the patient is sensed using the patient feedback device. At a first time, an electrical stimulus is applied with the IPG. The force sensor is monitored at a plurality of time points. A level of force sensed by the force sensor at each of the plurality of time points is recorded. A time point at which a maximum force is applied is identified, or a time point at which a minimum force is applied is identified. The first time is compared to the time point at which a minimum force is applied or the time point at which a maximum force is applied, in order to determine a patient response time.

Abstract translation: 用于电刺激系统的患者反馈装置被校准。 电刺激系统包括植入患者的可植入脉冲发生器（IPG）和具有力传感器的患者反馈装置。 使用患者反馈装置感测来自患者的输入。 第一次，IPG应用电刺激。 在多个时间点监测力传感器。 记录在多个时间点的每一个时由力传感器感测的力的水平。 识别施加最大力的时间点，或者识别施加最小力的时间点。 将第一次与施加最小力的时间点或施加最大力的时间点进行比较，以便确定患者的反应时间。

公开(公告)号：US09180302B2

公开(公告)日：2015-11-10

申请号：US14011156

申请日：2013-08-27

Applicant: Greatbatch Ltd.

Inventor： Scott Drees ,  Norbert Kaula ,  Yohannes Iyassu ,  Scott G. Leyh ,  Richard J. Polefko ,  Stephen C. Trier ,  Raymond L. Yoder

IPC: A61N1/00 ,  A61N1/372 ,  G06F3/0354 ,  G06F3/044

CPC classification number: A61N1/37247 ,  A61N1/37282 ,  G06F3/03545 ,  G06F3/03547 ,  G06F3/0412 ,  G06F3/044 ,  G06F3/04812 ,  G06F3/0488 ,  G06F2203/04104 ,  G06F2203/04106 ,  G06F2203/04108 ,  G06F2203/04801 ,  G09G3/36

Abstract: A method of visualizing a user interaction with a clinician programmer is disclosed. A user engagement with respect to a screen of the clinician programmer is detected via one or more sensors associated with the screen of the clinician programmer. One or more locations on the screen of the clinician programmer corresponding to the user engagement is determined. An external monitor is communicatively coupled to the clinician programmer. The external monitor displays one or more cursors that graphically represent the one or more locations on the screen of the clinician programmer corresponding to the user engagement, respectively.

Abstract translation: 公开了一种可视化与临床医师程序员的用户交互的方法。 通过与临床医生编程器的屏幕相关联的一个或多个传感器来检测与临床医生编程器的屏幕的用户接合。 确定对应于用户参与的临床医师程序员的屏幕上的一个或多个位置。 外部监视器通信耦合到临床医生程序员。 外部监视器分别显示一个或多个图形地分别表示与用户参与对应的临床医师编程器的屏幕上的一个或多个位置的光标。

公开(公告)号：US20150134026A1

公开(公告)日：2015-05-14

申请号：US14536863

申请日：2014-11-10

Applicant: Greatbatch Ltd.

Inventor： Norbert Kaula ,  Yohannes Iyassu

IPC: A61N1/36 ,  A61N1/372

CPC classification number: A61N1/0558 ,  A61N1/05 ,  A61N1/0512 ,  A61N1/0551 ,  A61N1/36007 ,  A61N1/3606 ,  A61N1/36132 ,  A61N1/36146 ,  A61N1/37235 ,  A61N1/37247

Abstract: In response to input from a patient who is being treated by a sacral nerve stimulation therapy, an electronic diary is generated that includes a plurality of voiding responses of the patient over a period of time. The sacral nerve stimulation therapy includes electrical pulses delivered to the patient according to a first stimulation program and via a first subset of electrode contacts on a lead that is implanted in the patient. The lead has a plurality of electrode contacts that include the first subset. Based on the voiding responses in the electronic diary, a loss of efficacy of the sacral nerve stimulation therapy is detected. The sacral nerve stimulation therapy is automatically adjusted in response to the detected loss of efficacy. The automatically adjustment of the sacral nerve stimulation therapy may include either a program-based sweep or a contact-based sweep.

Abstract translation: 响应于通过骶神经刺激疗法治疗的患者的输入，产生包括患者在一段时间内的多个排尿反应的电子日记。 骶神经刺激治疗包括根据第一刺激程序传送给患者的电脉冲，并且经由植入患者的引线上的电极接触的第一子集。 引线具有包括第一子集的多个电极接触。 根据电子日记中的排尿反应，检测到骶神经刺激疗法的功效丧失。 响应于检测到的功效丧失，自动调整骶神经刺激疗法。 骶神经刺激治疗的自动调整可以包括基于程序的扫描或基于接触的扫描。

公开(公告)号：US20140343633A1

公开(公告)日：2014-11-20

申请号：US14451830

申请日：2014-08-05

Applicant: Greatbatch Ltd.

Inventor： Norbert Kaula ,  Jeff A. Weisgarber ,  Yohannes Iyassu

IPC: G01R19/25 ,  A61N1/05

CPC classification number: G01R19/2503 ,  A61N1/025 ,  A61N1/04 ,  A61N1/0488 ,  A61N1/05 ,  A61N1/08 ,  A61N1/3752

Abstract: An electrically identifiable medical electrode lead. The lead includes a flexible lead body having a distal end and a connector end. The lead also includes a plurality of electrodes disposed near the distal end of the flexible lead body. The lead further includes a connector disposed at the connector end of the flexible lead body, the connector including a plurality of contacts. The lead additionally includes a plurality of conductors supported by and passing through the flexible lead body, the plurality of conductors including electrical conductors that provide paths for electrical current from the connector to the plurality of electrodes. Finally, the lead includes a memory circuit supported by the flexible lead body and being in electrical communication with a contact of the plurality of contacts in the connector.

Abstract translation: 电可识别的医用电极引线。 引线包括具有远端和连接器端的柔性引线体。 引线还包括设置在柔性引线主体的远端附近的多个电极。 引线还包括设置在柔性引线主体的连接器端处的连接器，该连接器包括多个触点。 引线还包括由柔性引线主体支撑并穿过柔性引线主体的多个导体，所述多个导体包括提供用于从连接器到多个电极的电流的路径的电导体。 最后，引线包括由柔性引线体支撑并与连接器中的多个触点的触点电连通的存储器电路。

公开(公告)号：US20140343628A1

公开(公告)日：2014-11-20

申请号：US14279841

申请日：2014-05-16

Applicant: Greatbatch Ltd.

Inventor： Norbert Kaula ,  Yohannes Iyassu

IPC: A61N1/36 ,  A61N1/372

CPC classification number: A61N1/37247 ,  A61N1/36185 ,  G06F3/0482 ,  G06F3/0484 ,  G06F3/04842 ,  G06F3/04847 ,  G06F3/0485 ,  G06F19/00 ,  G06F19/3481 ,  G16H20/30 ,  G16H40/63 ,  G16H50/50

Abstract: A method of programming electrodes includes automatic current balancing and lock control. A virtual representation of a lead is displayed. The lead includes a plurality of electrodes. A subset of the electrodes is selected for programming. Each of the electrodes in the subset has one of two polarities. The two polarities are anode and cathode. A first percentage of a total stimulation current is assigned to a first one of the electrodes in the subset. In response to a user input, the first percentage is fixed to the first electrode. A plurality of second electrodes in the subset that have the same polarity as the first electrode is identified. Thereafter, a respective second percentage of the total stimulation current is automatically assigned to each of the second electrodes. A sum of the first percentage and the respective second percentages is equal to 100%.

Abstract translation: 一种编程电极的方法包括自动电流平衡和锁定控制。 显示线索的虚拟表示。 引线包括多个电极。 选择电极的子集进行编程。 子集中的每个电极具有两个极性之一。 这两个极性是阳极和阴极。 总刺激电流的第一百分比被分配给子集中的第一个电极。 响应于用户输入，第一百分比被固定到第一电极。 识别出具有与第一电极相同极性的子集中的多个第二电极。 此后，相应的第二百分比的总刺激电流被自动分配给每个第二电极。 第一百分比和相应的第二百分比的总和等于100％。

公开(公告)号：US20140304773A1

公开(公告)日：2014-10-09

申请号：US14245225

申请日：2014-04-04

Applicant: Greatbatch Ltd.

Inventor： Thomas F. Woods ,  Norbert Kaula ,  Yohannes Iyassu

IPC: H04L29/06 ,  A61B5/00 ,  A61N1/372

CPC classification number: H04L63/08 ,  A61B5/002 ,  A61B5/0031 ,  A61B5/7475 ,  A61N1/37247 ,  H04L63/083 ,  H04L63/0861 ,  H04L67/12

Abstract: The present disclosure involves a method of communicating with an implantable medical device. An authentication process is performed to verify an identity of a user of a mobile computing device. A request is received from the user to access an implantable medical device via the mobile computing device. Based on the identity of the user, a first user interface suitable for the user is selected from a plurality of user interfaces that are each configured to control an implantable medical device. The plurality of user interfaces have different visual characteristics and different levels of access to the implantable medical device. The first user interface is displayed on the mobile computing device.

Abstract translation: 本公开涉及与可植入医疗装置通信的方法。 执行认证处理以验证移动计算设备的用户的身份。 从用户接收到经由移动计算设备访问可植入医疗设备的请求。 基于用户的身份，从多个用户界面中选择适合用户的第一用户界面，每个用户界面被配置为控制可植入医疗设备。 多个用户界面具有不同的视觉特征和对可植入医疗装置的不同级别的访问。 第一用户界面显示在移动计算设备上。

公开(公告)号：US20140249599A1

公开(公告)日：2014-09-04

申请号：US14279415

申请日：2014-05-16

Applicant: Greatbatch Ltd.

Inventor： Norbert Kaula ,  Yohannes Iyassu

IPC: A61N1/36

CPC classification number: A61N1/36071 ,  A61N1/36132 ,  A61N1/36185 ,  A61N1/37247 ,  G06F19/00 ,  G06F19/3481 ,  G16H40/63

Abstract: A computer assisted programming method includes ramping up a stimulation current for a plurality of contacts on a lead. Patient feedback is received while the stimulation current is being ramped up. Patient feedback indicates that the patient is beginning to feel stimulation. Based on the patient feedback, amplitude of the stimulation current that resulted in the patient feedback is recorded, and contacts are divided into groups. The contacts are activated one group at a time to the recorded amplitude. For each activated group of contacts, whether the patient can feel stimulation is determined. Thereafter, the target group that caused the patient to feel stimulation is then sub-divided into sub-groups. This process repeats a plurality of cycles until one or more contacts that caused the patient to feel stimulation are identified. The recorded amplitude is assigned as a perception threshold for the identified one or more contacts.

Abstract translation: 计算机辅助编程方法包括增加引线上的多个触点的刺激电流。 当刺激电流正在上升时，接收到患者反馈。 患者反馈表明患者开始感觉到刺激。 根据患者反馈，记录导致患者反馈的刺激电流的幅度，将接触分成组。 触点一次被激活到记录的幅度。 对于每个激活的接触组，确定患者是否感觉到刺激。 此后，导致患者感觉到刺激的目标群体然后被分为亚组。 该过程重复多个周期，直到导致患者感觉到刺激的一个或多个接触被识别。 记录的幅度被分配为所识别的一个或多个触点的感知阈值。

公开(公告)号：US20140067354A1

公开(公告)日：2014-03-06

申请号：US13973268

申请日：2013-08-22

Applicant: Greatbatch Ltd.

Inventor： Norbert Kaula ,  Yohannes Iyassu

IPC: G06F19/00

CPC classification number: G16H50/50 ,  A61N1/36128 ,  A61N1/37247 ,  G06F19/3481 ,  G09B23/28 ,  G09B23/30

Abstract: The present disclosure involves a method of determining stimulation lead placements for a healthcare professional with respect to an implant of a neurostimulator device in a target patient. A human body model is provided. A pain map is generated over the human body model in response to user input. The pain map visually represents body regions of the target patient that are experiencing pain. A dermatome map is provided. The dermatome map includes a visual correlation between regions of a human body and segments of a spinal cord. The pain map is compared with the dermatome map. Recommendations regarding the implant of the neurostimulator device are displayed in response to the comparing.

Abstract translation: 本公开涉及一种确定医疗保健专业人员相对于目标患者中的神经刺激器装置的植入物的刺激引线放置的方法。 提供人体模型。 响应于用户输入，在人体模型上产生疼痛图。 疼痛图可视地表示正在经历疼痛的目标患者的身体区域。 提供皮肤图。 皮肤图包括人体的区域和脊髓的部分之间的视觉相关性。 疼痛图与皮肤图比较。 关于神经刺激器装置的植入的建议是响应于比较显示的。