摘要:
An injection system for co-delivery of two medicaments (1, 2) having a drug delivery device (7) containing a primary reservoir (11) containing a first medicament (1) and having a secondary reservoir (5, 17, 30) containing a second medicament (2) where the drug delivery device (7) has only one dose setter (12) for the primary reservoir (11) and that automatically determines the dose of the second medicament (2). Both medicaments (1, 2) are delivered through a single dispense interface (3, 16, 21, 31).
摘要:
A medicated module for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module containing a single dose of a secondary medicament and where both medicaments are delivered through a hollow needle. The medicated module is user selectable so that it will deliver a priming dose of a primary medicament or both the primary and secondary medicaments. The module also contains a needle guard that locks after dose delivery. The needle guard prevents accidental needle sticks before and after an injection. A locking collar rotates during use as an inner protrusion follows three paths of a track located on the outer surface of a body housing. When the inner facing protrusion is in the third path, it encounters a hard stop and a rotational bias that locks the guard from further refraction and thus covers the sharp distal end of the needle.
摘要:
A medicated module (4) for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module (4) containing a single dose of a secondary medicament (2) and where both medicaments are delivered through a single hollow needle (5). The medicated module (4) is user selectable so that it will deliver both the primary (1) and secondary medicaments (2), or only the primary medicament (1). The module (4) also contains a guard (42) that locks after dose delivery.
摘要:
A injection system for co-delivery of two medicaments (1, 2) having a drug delivery device (10) containing a primary reservoir containing a first medicament (1) and that has a secondary reservoir containing a second medicament (2) where the drug delivery device (10) has only one dose setter (12) for the primary reservoir and that automatically determines the dose of the second medicament (2). Both medicaments (1, 2) are delivered through a single dispense interface.
摘要:
A drug delivery device having a collar and a linkage component. The drug delivery device includes a variable dose setting mechanism, a fixed dose setting mechanism, a single dose setter, a collar, and a linkage component. The variable dose setting mechanism is operably coupled to a primary reservoir holding a first medicament. The fixed dose setting mechanism is operably coupled to a secondary reservoir holding a second medicament. Further, the single dose setter is operably coupled to the variable dose setting mechanism, and the collar is disposed on the variable dose setting mechanism. Still further, the linkage component is disposed on the fixed dose setting mechanism, wherein the linkage component is capable of engagement with the collar.
摘要:
A medicated module (100) is attachable to a drug delivery device (102). The medicated module (100) includes a housing (104) having a proximal end and a distal end, the proximal end has a connector (110) configured for attachment to a drug delivery device (102). The distal end contains a shuttle (112). A first needle (114) is fixed in the housing (104) and a second needle (116) is fixed in the shuttle (112). The medicated module (100) also includes a reservoir (118) in the housing (104) comprising a medicament (12). Further, the medicated module (100) includes a guard assembly (122) positioned in the housing (104) and configured to move in an axial direction during application to an injection site. Preferably, the medicated module (100) is locked out after at least two injections of the medicament (105) contained in the drug delivery device (102).
摘要:
A medicated module for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module containing a single dose of a secondary medicament and where both medicaments are delivered through a hollow needle. The medicated module does not require the user to manually engage a reservoir containing the secondary medicament. Instead, a rotating housing automatically activates the reservoir when the needle guard is retracted. The needle guard prevents accidental needle sticks after an injection, and locks after dose delivery.
摘要:
A medicated module for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module containing a single dose of a secondary medicament and where both medicaments are delivered through a hollow needle. The medicated module is initially in a locked state until attached to a drug delivery where interaction of the cartridge holder with the module bypass housing changes the module to a triggerable state. The medicated module does not require the user to manually engage a reservoir containing the secondary medicament. Instead, a biasing member automatically activates the reservoir when the needle guard is retracted when the module is in the triggerable state. The needle guard prevents accidental needle sticks before and after an injection, and locks after removal from the injection site.
摘要:
A module assembly for use with an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts the module that has an automatic triggering system activated by a dispense interface needle guard. When the module contains a single dose of a secondary medicament, both the primary and secondary medicaments are delivered through a single dispense interface, preferably a hollow needle. The module assembly does not require the user to manually engage a reservoir containing the secondary medicament. Instead, a trigger automatically activates movement of a lower hub when the needle guard is retracted.
摘要:
Disclosed herein are various examples of a medicated module that can be attached to a drug delivery device such that a user can administer a user settable dose of a first medicament and a fixed dose of a second medicament through a single dispense interface. In one example, the medicated module includes (i) an outer housing having a hub that holds a first needle, (ii) a bypass housing including a reservoir containing a second medicament, (iii) a lower hub including a second needle, (iv) a slidable needle guard including at least one disengagement member, where the needle guard is configured to activate the medicated module by forcing the bypass housing to disengage from the outer housing at a pre-defined amount of proximal displacement of the needle guard; and (v) a biasing member, where the biasing member is configured to place the second needle in fluid communication with the first and second medicaments automatically after activation of the medicated module.