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公开(公告)号:US06562317B2
公开(公告)日:2003-05-13
申请号:US09785274
申请日:2001-02-20
申请人: Richard J. Greff , George Wallace
发明人: Richard J. Greff , George Wallace
IPC分类号: A61K5100
CPC分类号: A61K51/06 , A61K51/1217 , A61K2121/00
摘要: Disclosed are novel radioactive compositions which are particularly suited for treating solid mass tumors via catheter delivery.
摘要翻译: 公开了特别适用于通过导管递送治疗固体肿瘤的新型放射性组合物。
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公开(公告)号:US06555104B2
公开(公告)日:2003-04-29
申请号:US09848303
申请日:2001-05-04
申请人: George Wallace , Richard J. Greff
发明人: George Wallace , Richard J. Greff
IPC分类号: A61K3174
CPC分类号: A61K49/048 , A61K31/717 , A61K31/765 , A61K49/0002
摘要: Disclosed are methods for treating incontinence in a mammal wherein a composition comprising a biocompatible polymer, a biocompatible solvent, and a contrast agent is delivered to the periurethral tissue of a mammal.
摘要翻译: 公开了用于治疗哺乳动物中失禁的方法,其中将包含生物相容性聚合物,生物相容性溶剂和造影剂的组合物递送至哺乳动物的尿道周围组织。
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公开(公告)号:US06241719B1
公开(公告)日:2001-06-05
申请号:US09311802
申请日:1999-05-13
申请人: George Wallace , Richard J. Greff
发明人: George Wallace , Richard J. Greff
IPC分类号: A61M3100
CPC分类号: A61F2/958 , A61F2210/0095 , A61K51/1282 , A61M2025/1086 , A61N5/1002
摘要: Disclosed are methods for the endovascular formation of a radioactive stent using a radioactive composition. These compositions are delivered to one or more vascular sites in a mammal as a fluid composition which solidifies in vivo to form a solid, coherent radioactive mass, preferably in the form or a stent. The solidified mass stents the vascular site thereby delivering the radioactivity attendant with the composition resulting in inhibition of restenosis.
摘要翻译: 公开了使用放射性组合物的放射性支架的血管内形成的方法。 这些组合物作为流体组合物递送至哺乳动物的一个或多个血管部位,其在体内固化以形成固体,相干放射性质量,优选为形式或支架。 凝固的质量支架血管部位,从而输送伴随该组合物的放射性物质,从而抑制再狭窄。
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34.
公开(公告)号:US06168777A
公开(公告)日:2001-01-02
申请号:US09185147
申请日:1998-11-03
申请人: Richard J. Greff , George Wallace
发明人: Richard J. Greff , George Wallace
IPC分类号: A61K5112
CPC分类号: A61K51/06 , A61K51/1217 , A61K2121/00
摘要: Disclosed are methods for treating solid mass prostate tumors in a male mammal by use of a radiation composition.
摘要翻译: 公开了通过使用辐射组合物治疗雄性哺乳动物中的固体质量前列腺肿瘤的方法。
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35.
公开(公告)号:US6146373A
公开(公告)日:2000-11-14
申请号:US953149
申请日:1997-10-17
申请人: Andrew H. Cragg , Richard J. Greff , Robert Pecor , John Perl , Blair Walker , George Wallace
发明人: Andrew H. Cragg , Richard J. Greff , Robert Pecor , John Perl , Blair Walker , George Wallace
CPC分类号: A61B17/12022 , A61B17/12113 , A61B17/12186 , A61B17/00491 , A61B2017/00495 , A61B2017/1205 , A61B90/39 , A61M2025/0034 , A61M2025/0037 , A61M2025/0039 , A61M25/00 , A61M25/0097
摘要: A catheter according to the present invention includes a multiple lumen catheter for delivery of a liquid embolic composition through a first lumen and delivery of a solidification agent through a second lumen. The catheter allows adjustment of the relative longitudinal position of the two lumens to control the solidification of the embolic composition within a blood vessel. The multiple lumen catheter system is used by inserting the catheter endovascularly into an aneurysm site and injecting a liquid embolic composition through the first lumen while injecting a solidification agent through the second lumen to wash the area of the aneurysm of blood which has become saturated with solvent, while replacing it with a fresh solidification agent. The controlled solidification of the liquid embolic composition by use of the solidification agent allows the aneurysm to be filled precisely and rapidly even when the aneurysm is located such that gravity does not cause the liquid embolic composition to flow into the aneurysm.
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公开(公告)号:US6015541A
公开(公告)日:2000-01-18
申请号:US962819
申请日:1997-11-03
申请人: Richard J. Greff , George Wallace
发明人: Richard J. Greff , George Wallace
IPC分类号: A61K47/30 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/38 , A61K49/04 , A61K51/00 , A61K51/06 , A61K51/12 , A61N5/10 , A61P35/00
CPC分类号: A61K51/06 , A61K51/1217 , A61K2121/00
摘要: Disclosed are novel radioactive compositions which are particularly suited for treating solid mass tumors via catheter delivery.
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公开(公告)号:US6007573A
公开(公告)日:1999-12-28
申请号:US707996
申请日:1996-09-18
申请人: George Wallace , Jay Lenker , Thomas J. Berryman
发明人: George Wallace , Jay Lenker , Thomas J. Berryman
CPC分类号: A61F2/962 , A61B17/12118 , A61B17/1214 , A61F2/92 , A61B17/12022 , A61B17/122 , A61F2/90 , A61F2002/9511 , A61F2210/0076 , A61F2230/0095 , A61F2250/0098
摘要: A stent and stent catheter for intra-cranial use. The stent is a rolled sheet stent and is releasably mounted on the distal tip of the catheter with a low profile retaining tab. The stent is rolled tightly on the distal tip of the catheter and flexibility of the tightly rolled stent is promoted by ribbed or slatted construction (or, alternatively, slotted construction) in which the various layers of the stent are provided with numerous slats which counter align when the stent is expanded to form an imperforate wall from a plurality of perforate layers.
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公开(公告)号:US5958444A
公开(公告)日:1999-09-28
申请号:US874677
申请日:1997-06-13
申请人: George Wallace , Richard J. Greff
发明人: George Wallace , Richard J. Greff
CPC分类号: A61L31/042 , A61L31/048 , A61F2/0036 , Y10S514/953
摘要: Disclosed are methods for treating vesicoureteral reflux in a mammal wherein a composition comprising a water insoluble biocompatible polymer and a biocompatible solvent is delivered to the subureteral tissue of the mammal.
摘要翻译: 公开了用于治疗哺乳动物膀胱输尿管反流的方法,其中将包含水不溶性生物相容性聚合物和生物相容性溶剂的组合物递送至哺乳动物的输尿管组织。
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公开(公告)号:US08663304B2
公开(公告)日:2014-03-04
申请号:US12136749
申请日:2008-06-10
IPC分类号: A61F2/06
CPC分类号: A61F2/962 , A61B17/12022 , A61B17/12118 , A61B17/1214 , A61B17/122 , A61B2017/1205 , A61B2017/12063 , A61B2017/12068 , A61F2/90 , A61F2/92 , A61F2002/823 , A61F2002/9511 , A61F2002/9517 , A61F2210/0076 , A61F2230/0095 , A61F2250/0071 , A61F2250/0098
摘要: A stent and stent catheter for intra-cranial use, and a method of treating vascular disease in blood vessels in the brain.
摘要翻译: 用于颅内使用的支架和支架导管,以及治疗脑中血管中的血管疾病的方法。
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公开(公告)号:US20080243071A1
公开(公告)日:2008-10-02
申请号:US11694536
申请日:2007-03-30
IPC分类号: A61M31/00
CPC分类号: A61F5/0003 , A61F5/0036 , A61F5/0046
摘要: A gastric space filler device for treating obesity in a patient by reducing the stomach volume features at least one inflatable space filler with drag delivery and stimulation features and includes therapeutic devices and anchoring apparatus enabling tracking, visualization and optimized management of inter-balloon connecting sections, drug reservoirs and pumping systems along with related improvements.
摘要翻译: 一种用于通过减少胃体积特征的用于治疗患者肥胖的胃空间填充装置,具有药物递送和刺激特征的至少一个可充气空间填充物,并且包括能够跟踪,可视化和优化管理球囊间连接部分的治疗装置和锚定装置, 药物储库和抽水系统以及相关改进。
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