公开(公告)号：US5171470A

公开(公告)日：1992-12-15

申请号：US563698

申请日：1990-08-07

申请人： Hiroyuki Nohira ,  Takahiro Ishizuka ,  Kazuo Yoshinaga

发明人： Hiroyuki Nohira ,  Takahiro Ishizuka ,  Kazuo Yoshinaga

IPC分类号： C07C31/38 ,  C07C33/42 ,  C09K19/04

CPC分类号： C07C31/38 ,  C07C33/423 ,  C09K19/04

摘要： A bifunctional optically active liquid crystal intermediate compound represented by the following Formula (I): X--Y--C.sub.* H(M)--CH.sub.2 --OH is disclosed, wherein X represents CH.sub.2 .dbd.CH--, HOCH.sub.2 --CH.sub.2 --, HSCH.sub.2 --CH.sub.2 --, HOCH.sub.2 --, HOOC--, HOCH.sub.2 CH.dbd.CH--, CH.sub.3 CH(OH)-- or HOCH.sub.2 C.sub.* H(Z)--; Y represents --CH.sub.2).sub.n or --CH.sub.2 (.sub.m O).sub.l CH.sub.2 --, where n represents an integer of 1 to 18, m represents an integer of 1 to 12, and l represents an integer of 1 to 4; M and Z each represents halogen atom, an alkyl group or an alkoxy group, said halogen atom being selected from the group consisting of I, Cl, Br and F, and said alkyl group or alkoxy group having 1 to 8 carbon atoms; and the mark * represents an asymmetric carbon atom. A process for preparing the intermediate compound is also disclosed.

摘要翻译： 公开了由下式（I）表示的双官能光学活性液晶中间体化合物：XYC * H（M）-CH 2 -OH，其中X表示CH 2 = CH-，HOCH 2 -CH 2 - ，HSCH 2 -CH 2 - ，HOCH 2 - ，HOOC-，HOCH2CH = CH-，CH3CH（OH） - 或HOCH2C * H（Z） - ; Y表示-CH 2）n或-CH 2（mO）l CH 2 - ，其中n表示1至18的整数，m表示1至12的整数，l表示1至4的整数; M和Z各自表示卤素原子，烷基或烷氧基，所述卤素原子选自I，Cl，Br和F，所述烷基或具有1至8个碳原子的烷氧基; 标记*表示不对称碳原子。 还公开了制备中间体化合物的方法。

公开(公告)号：US5098600A

公开(公告)日：1992-03-24

申请号：US630845

申请日：1990-12-20

申请人： Shinichi Nakamura ,  Yoko Yamada ,  Hiroyuki Nohira ,  Takao Takiguchi ,  Takashi Iwaki ,  Takeshi Togano

发明人： Shinichi Nakamura ,  Yoko Yamada ,  Hiroyuki Nohira ,  Takao Takiguchi ,  Takashi Iwaki ,  Takeshi Togano

IPC分类号： C07D285/12 ,  C07D417/04 ,  C09K19/34 ,  C09K19/42

CPC分类号： C07D285/12 ,  C07D417/04 ,  C09K19/3497

摘要： There is provided a liquid crystal compound represented by the following general formula (I), a liquid crystal composite including at least one kind of above liquid crystal compound and a liquid crystal device in which the liquid crystal composite is disposed between a pair of electrode substrates. ##STR1## In the above formula (I), R.sub.1 is a straight chain alkyl having 1-12 carbon atoms. R.sub.2 is a straight chain or branched chain alkyl, which may have a substituted radical, having 1-18 carbon atoms and in which one or more than two methylene, which do not adjoin, may be substituted by --Y--, ##STR2## --CH.dbd.CH--, or --C.vertline.C--. Y is O or S. A is --A.sub.1 -- or --A.sub.1 --A.sub.2 --, and B is --B.sub.1 -- or --B.sub.1 --B.sub.2 --. A.sub.1, A.sub.2, B.sub.1, and B.sub.2 each is selected from ##STR3## and a single bond. Z is hydrogen, halogen, cyano or methyl. X.sub.1 is a single bond when A is a single bond and is --CH.sub.2 O--, ##STR4## in other cases. n is 0 or 1, ##STR5## --OCH.sub.2 -- or --CH.sub.2 O, and D is a single bond, ##STR6## and *designates an asymmetric carbon atom.

公开(公告)号：US5021593A

公开(公告)日：1991-06-04

申请号：US551110

申请日：1990-07-11

申请人： Hiroyuki Nohira ,  Hidemasa Takaya ,  Akira Miyashita

发明人： Hiroyuki Nohira ,  Hidemasa Takaya ,  Akira Miyashita

IPC分类号： B01J31/22 ,  C07B35/02 ,  C07B53/00 ,  C07B57/00 ,  C07B61/00 ,  C07C51/36 ,  C07C53/128 ,  C07C55/02 ,  C07C67/303 ,  C07C69/34 ,  C07C205/06 ,  C07C205/12 ,  C07C231/16 ,  C07C233/47 ,  C07C233/83 ,  C07F9/50 ,  C07F15/00 ,  C07F19/00

CPC分类号： C07C51/36 ,  C07C201/12 ,  C07C209/36 ,  C07C209/62 ,  C07C231/02 ,  C07F15/0053 ,  C07F9/5027

摘要： A ruthenium-optically active phosphine complex having, as a ligand, BICHEP which means 2,2'-bis(dicyclohexylphosphino)-6,6'-dimethyl-1,1'-biphenyl represented by formula (I): ##STR1## is disclosed, which can catalyze asymmetric syntheses, such as asymmetric hydrogenation, asymmetric isomerization, and asymmetric silylation, exhibiting excellent catalytic activity and providing high optical purity.

公开(公告)号：US4917817A

公开(公告)日：1990-04-17

申请号：US222426

申请日：1988-07-21

申请人： Hiroyuki Nohira ,  Masanao Kamei ,  Hideki Kanazawa ,  Tetsuya Abe ,  Yoko Yamada ,  Yuko Etoh

发明人： Hiroyuki Nohira ,  Masanao Kamei ,  Hideki Kanazawa ,  Tetsuya Abe ,  Yoko Yamada ,  Yuko Etoh

IPC分类号： C07B57/00 ,  C07B31/00 ,  C07B61/00 ,  C07C27/00 ,  C07C29/136 ,  C07C29/147 ,  C07C31/38 ,  C07C41/00 ,  C07C43/20 ,  C07C43/225 ,  C07C43/23 ,  C07C45/00 ,  C07C51/00 ,  C07C51/487 ,  C07C53/21 ,  C07C59/125 ,  C07C65/21 ,  C07C67/00 ,  C07C69/63 ,  C07C69/92 ,  C07C69/94 ,  C09K19/04 ,  C09K19/12 ,  C09K19/54 ,  C09K19/58

CPC分类号： C09K19/586 ,  C07C31/38 ,  C07C43/23 ,  C07C45/004 ,  C07C51/487 ,  C07C53/21 ,  C07C65/21 ,  C09K19/04 ,  C09K19/0403 ,  C09K19/126

摘要： An optically active functional compound represented by the following formula (1) is disclosed: ##STR1## wherein R denotes an alkyl group having 1-14 carbon atoms; -X- denotes ##STR2## denotes a single bond, ##STR3## n=0, 1 or 2; and C* denotes an asymmetric carbon atom. The compound of the formula (1) may be produced through an optically active compound of the following formula (2) or (3): ##STR4## The compounds of the above formulas (1)-(3) are all characterized by a trifluoromethyl group providing a large spontaneous polarization attached to an asymmetric carbon atom.

公开(公告)号：US4867903A

公开(公告)日：1989-09-19

申请号：US22928

申请日：1987-03-06

申请人： Hiroyuki Nohira ,  Masanao Kamei ,  Shinichi Nakamura ,  Kazuharu Katagiri

发明人： Hiroyuki Nohira ,  Masanao Kamei ,  Shinichi Nakamura ,  Kazuharu Katagiri

IPC分类号： C07C69/773 ,  C07D239/26 ,  C09K19/06 ,  C09K19/12 ,  C09K19/20 ,  C09K19/34 ,  C09K19/46 ,  C09K19/48

CPC分类号： C07D239/26 ,  C09K19/06 ,  C09K19/126 ,  C09K19/2021 ,  C09K19/3463 ,  C09K19/46 ,  C09K19/48

摘要： A fluoroalkane derivative represented by the formula: ##STR1## wherein R denotes an alkyl group having 1-16 carbon atoms, C* denotes an asymmetric carbon atom, R.sup.1 denotes an alkyl or alkoxy group having 1-16 carbon atoms; ##STR2## respectively denote a phenylene group ##STR3## a cyclohexylene group ##STR4## or a pyrimidinylene group ##STR5## p is 0 or 1, q is 0 or 1 when p is 1, r is 0 or 1; and l, m and n are respectively 0 or a positive integer satisfying the relationship of l+m+n.gtoreq.1. The fluoroalkane derivative has a fluorine atom providing a large dipole moment and directly connected to an asymmetric carbon atom, so that it provides a high speed responsive characteristic through an increased spontaneous polarization when contained in a liquid crystal composition, especially a ferroelectric liquid crystal composition.

摘要翻译： 由下式表示的氟烷烃衍生物：其中R表示具有1-16个碳原子的烷基，C *表示不对称碳原子，R1表示具有1-16个碳原子的烷基或烷氧基; 分别表示亚苯基“亚甲基”或“嘧啶基”，p为0或1，当p为1时，q为0或1，r为0或1; l，m和n分别为0或满足l + m + n> / = 1的关系的正整数。 氟烷烃衍生物具有提供大的偶极矩并直接连接到不对称碳原子的氟原子，从而当包含在液晶组合物，特别是铁电液晶组合物中时，通过增加的自发极化提供高速响应特性。

公开(公告)号：US4845272A

公开(公告)日：1989-07-04

申请号：US207229

申请日：1988-06-16

申请人： Hiroyuki Nohira ,  Shinichi Yoshida

发明人： Hiroyuki Nohira ,  Shinichi Yoshida

IPC分类号： C07B57/00 ,  C07C51/487 ,  C07C61/40 ,  C07C67/48 ,  C07C69/747

CPC分类号： C07C51/487

摘要： A method for optically resolving (.+-.)-cis or (.+-.)-trans-permethric acid which comprises reacting (.+-.)-cis-permethric acid and optically active 1-(p-tolyl)ethylamine or optically active cis-N-benzyl-2-(hydroxymethyl)cyclohexylamine, or reaction (.+-.)-trans-permethric acid and optically active 1-(p-isopropylphenyl)ethylamine, optically active 1-ethylbenzylamine or optically active cis-N-benzyl-2-(hydroxymethyl)cyclohexylamine.

公开(公告)号：US06603032B1

公开(公告)日：2003-08-05

申请号：US10148895

申请日：2002-06-18

申请人： Masashi Sugiya ,  Hiroyuki Nohira

发明人： Masashi Sugiya ,  Hiroyuki Nohira

IPC分类号： C07F950

CPC分类号： C07F9/5027 ,  B01J31/24 ,  B01J2231/645 ,  B01J2531/822 ,  C07B53/00

摘要： The present invention provides a novel bisphosphine compound having a chiral center on the phosphorus atom, which is suitable as a ligand for an asymmetric catalyst for use in asymmetric hydrogenation, this bisphosphine compound being represented by the following formula (1): (where t—C8H17 denotes 1,1,3,3-tetramethylbutyl), and a process for the production of this bisphosphine compound. Also provided are a transition metal complex having this bisphosphine compound as a ligand, and a process for the asymmetric hydrogenation of an unsubstituted carboxylic acid or its ester.

摘要翻译： 本发明提供了一种在磷原子上具有手性中心的新型双膦化合物，其适合作为用于不对称氢化的不对称催化剂的配体，该双膦化合物由下式（1）表示:(其中t- C8H17表示1,1,3,3-四甲基丁基），以及该双膦化合物的制造方法。 还提供了具有这种双膦化合物作为配体的过渡金属络合物，以及未取代的羧酸或其酯的不对称氢化的方法。

公开(公告)号：US06177591B1

公开(公告)日：2001-01-23

申请号：US09371050

申请日：1999-08-10

申请人： Masashi Sugiya ,  Hiroyuki Nohira

发明人： Masashi Sugiya ,  Hiroyuki Nohira

IPC分类号： C07B5700

CPC分类号： C07F9/5304

摘要： An optically active 1-phenylethylamine is reacted to a phosphine oxide carboxylic acid of a racemic modification shown by the following general formula (2): and a produced diastereomeric salt is separated using the difference in solubility against a solvent, which is subsequently decomposed by acid, so as to free and separate an optically active phosphine oxide carboxylic acid.

摘要翻译： 将光学活性的1-苯基乙胺与由以下通式（2）表示的外消旋化合物的氧化膦羧酸反应：使用与溶剂分解的溶剂的差异分离生成的非对映异构体盐，其随后被酸分解 ，以便游离和分离光学活性氧化膦羧酸。

公开(公告)号：US5720898A

公开(公告)日：1998-02-24

申请号：US332475

申请日：1994-10-31

申请人： Hiroyuki Nohira ,  Yuuta Kumano ,  Kazuharu Katagiri ,  Kenji Shinjo ,  Kazuo Yoshinaga

发明人： Hiroyuki Nohira ,  Yuuta Kumano ,  Kazuharu Katagiri ,  Kenji Shinjo ,  Kazuo Yoshinaga

IPC分类号： C09K19/38 ,  C09K19/40 ,  G02F1/1333 ,  C09K19/52 ,  G02F1/13

CPC分类号： C09K19/3804 ,  C09K19/408 ,  G02F1/133365

摘要： A liquid crystal composition, comprising a main chain-type mesomorphic polymer and a mesomorphic monomer and showing a smectic phase including a plurality of molecular layers, wherein a linkage of a covalent bond is present between adjacent molecular layers among the plurality molecular layers. Because of the presence of the covalent bond linkage between the molecular layers, the elastic energy of the liquid crystal per se relating to the elastic energy between the smectic liquid crystal molecular layers can be controlled to provide a uniform alignment. The mesomorphic polymer preferably has a structure represented by the following formula (1): ##STR1## wherein A denotes a terminal flexible chain group, M denotes a mesogen group, F denotes a spacer flexible chain group, x is 0 or 1, B denotes an ester bond group, ether bond group, thioester bond group, dimethylsiloxane bond group or thioether bond group, and y is 1-200.

摘要翻译： 一种液晶组合物，其包含主链型介晶聚合物和介晶单体，并且显示包含多个分子层的近晶相，其中在多个分子层之间的相邻分子层之间存在共价键的键。 由于存在分子层之间的共价键，因此可以控制与近晶型液晶分子层之间的弹性能相关的液晶本身的弹性能量，以提供均匀的取向。 介晶聚合物优选具有由下式（1）表示的结构：其中A表示末端柔性链基，M表示介晶基，F表示间隔基柔性链基，x为0或1 B表示酯键基团，醚键基团，硫酯键合基团，二甲基硅氧烷键合基团或硫醚键基团，y表示1-200。

公开(公告)号：US5690858A

公开(公告)日：1997-11-25

申请号：US714512

申请日：1996-09-16

申请人： Hiroyuki Nohira ,  Michihiro Yamada ,  Kazuo Yoshinaga

发明人： Hiroyuki Nohira ,  Michihiro Yamada ,  Kazuo Yoshinaga

IPC分类号： C08G77/38 ,  C09K19/40 ,  C09K19/52

CPC分类号： C09K19/406 ,  C08G77/38 ,  C09K19/408 ,  Y10T428/1014

摘要： A mesomorphic compound represented by the following formula (I): ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 independently denote methyl group or a mesomorphic residual group, at least one of R.sub.1, R.sub.2 and R.sub.3 being a mesomorphic residual group having an optically active group of the formula below as a terminal flexible group: ##STR2## wherein R.sub.4 is an alkyl group having 1-12 carbon atoms; n is an integer of 0-10; m is an integer of 1-10; and L is an integer of 1-100. The mesomorphic compound is usable for constituting a liquid crystal composition and a liquid crystal device having a large picture area and capable of showing an improved switching characteristic and a good impact resistance.

摘要翻译： 由下式（I）表示的介晶化合物：其中R 1，R 2和R 3独立地表示甲基或介晶残基，R 1，R 2和R 3中的至少一个是具有光学活性基团的介晶残余基团 作为末端柔性基团的下式：其中R 4是具有1-12个碳原子的烷基; n是0-10的整数; m为1-10的整数; L为1-100的整数。 介晶化合物可用于构成液晶组合物和具有大图像面积并且能够显示出改进的切换特性和良好的耐冲击性的液晶装置。