公开(公告)号：US10722640B2

公开(公告)日：2020-07-28

申请号：US16053227

申请日：2018-08-02

Applicant: Insulet Corporation

Inventor： Ian McLaughlin

IPC: A61M5/00 ,  A61L2/20 ,  A61M5/31 ,  A61L2/00 ,  A61M5/142

Abstract: A system for sterilizing a drug delivery device includes a drug delivery device having a first self-healing seal configured to seal a fluid reservoir disposed within the drug delivery device. A sealable container is configured to receive the drug delivery device therein. The sealable container has a base portion and a cover portion. The cover portion has a second self-healing seal positioned to align with the first self-healing seal when the drug delivery device is disposed within the sealable container. A fill port includes a fill path, the fill path being configured to pass through the first and second self-healing seals to fluidly couple the fill port to the reservoir of the drug delivery device. Other systems, methods, and devices of sterilization are also disclosed.

公开(公告)号：US10561797B2

公开(公告)日：2020-02-18

申请号：US15676604

申请日：2017-08-14

Applicant: Insulet Corporation

Inventor： David Nazzaro ,  Ian McLaughlin ,  Daniel Allis ,  Simon Kozin ,  Maureen McCaffrey

IPC: A61M5/315 ,  A61M5/142 ,  A61M5/145 ,  A61M5/20

Abstract: Systems and methods for monitoring an operational state and/or a fill status of a drug container of a drug delivery device are provided. The drug container can hold a liquid drug. A plunger can be positioned within the drug container. A drive system can advance the plunger to expel the liquid drug from the container. A monitoring system can detect a movement and/or a position of the plunger and/or any component coupled to the plunger. The detection can enable determination of an amount of liquid drug that has been expelled and/or an amount of liquid drug remaining in the drug container. Dosing rates, flow rates, and dosage completion can also be determined.

公开(公告)号：US10245377B2

公开(公告)日：2019-04-02

申请号：US15809532

申请日：2017-11-10

Applicant: Insulet Corporation

Inventor： Ian McLaughlin

IPC: A61M5/168 ,  A61M5/162 ,  A61M5/24 ,  A61L2/00 ,  A61M5/00 ,  A61M5/145 ,  A61M5/19 ,  A61M5/31 ,  A61M5/32 ,  A61M39/10 ,  A61L2/07 ,  A61L2/08 ,  A61L2/20

Abstract: The present disclosure relates generally to the field of drug delivery. In particular, the present disclosure relates to a drug delivery system that includes a sealed and sterile fluid path attached to a drug-loaded container. The disclosure further relates to methods for sterilizing a portion of the drug delivery system without exposing the drug-loaded container to harmful sterilization parameters.

公开(公告)号：US20140127048A1

公开(公告)日：2014-05-08

申请号：US13854456

申请日：2013-04-01

Applicant: Insulet Corporation

Inventor： Steven DiIanni ,  Ian McLaughlin ,  Jason Brian O'Connor ,  Robert Campbell ,  Kevin Schmid

IPC: F04B9/02

CPC classification number: A61M5/14566 ,  A61B5/14532 ,  A61B5/14865 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/1452 ,  A61M5/158 ,  A61M5/1723 ,  A61M5/3291 ,  A61M2005/1403 ,  A61M2005/14252 ,  A61M2005/14506 ,  A61M2230/201 ,  F04B9/02 ,  F04C2270/041

Abstract: A fluid delivery device comprising a fluid reservoir; a transcutaneous access tool fluidly coupled to the fluid reservoir; and a drive mechanism for driving fluid from the reservoir, the drive mechanism comprising a plunger received in the reservoir; a leadscrew extending from the plunger; a nut threadably engaged with the leadscrew; a drive wheel; and a clutch mechanism coupled to the drive wheel, wherein the clutch mechanism is configured to allow the nut to pass through when disengaged and is configured to grip the nut when engaged such that the drive wheel rotates the nut to advance the drive rod and the plunger into the reservoir.

Abstract translation: 一种流体输送装置，包括流体储存器; 与液体储存器流体耦合的经皮通路工具; 以及用于驱动来自储存器的流体的驱动机构，所述驱动机构包括容纳在所述储存器中的柱塞; 从柱塞延伸的丝杠; 与丝杠螺纹接合的螺母; 驱动轮 以及联接到所述驱动轮的离合器机构，其中所述离合器机构构造成允许所述螺母在分离时通过，并且构造成在接合时夹紧所述螺母，使得所述驱动轮旋转所述螺母以使所述驱动杆和所述柱塞 进入水库。

公开(公告)号：US11819675B2

公开(公告)日：2023-11-21

申请号：US17125150

申请日：2020-12-17

Applicant: Insulet Corporation

Inventor： Maureen McCaffrey ,  Ian McLaughlin

IPC: A61M5/32 ,  A61M5/142 ,  A61M5/158 ,  A61M5/168

CPC classification number: A61M5/3287 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/158 ,  A61M5/168 ,  A61M2005/14252 ,  A61M2005/1583 ,  A61M2005/1585

Abstract: A needle mechanism module for automatically inserting a fluid path into a patient for drug delivery is provided. The needle mechanism module can be a component of a wearable drug delivery device. The needle mechanism module can insert a needle and cannula into the patient responsive to activation of the drug delivery device by a user. After insertion, the needle can be automatically retracted, leaving only the cannula in the patient. As a result, discomfort of the user is reduced.

公开(公告)号：US11786668B2

公开(公告)日：2023-10-17

申请号：US16140165

申请日：2018-09-24

Applicant: Insulet Corporation

Inventor： David Nazzaro ,  Ian McLaughlin ,  Jeff Barnes ,  Daniel Allis

IPC: A61M5/315 ,  A61M5/32 ,  A61M5/24 ,  A61M5/142 ,  A61M5/145

CPC classification number: A61M5/31565 ,  A61M5/1454 ,  A61M5/14248 ,  A61M5/2455 ,  A61M5/3287 ,  A61M2005/14252 ,  A61M2005/14268 ,  A61M2005/14506 ,  A61M2005/31518

Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can include a spring coupled to a plurality of force transfer elements. The force transfer elements can have a variety of shapes and configurations.

公开(公告)号：US11725741B2

公开(公告)日：2023-08-15

申请号：US16514183

申请日：2019-07-17

Applicant: Insulet Corporation

Inventor： Ian McLaughlin ,  Daniel Allis

IPC: F16K11/07 ,  F16K99/00 ,  G05D7/01 ,  A61M5/142 ,  A61M39/22

CPC classification number: F16K11/0716 ,  A61M5/14216 ,  A61M39/223 ,  F16K99/0011 ,  F16K99/0057 ,  G05D7/0153 ,  A61M2039/224 ,  F16K2099/0086

Abstract: Disclosed are examples of valve systems and methods of operating the respective valve systems. An example valve system may include a valve body, an inlet component, an outlet component and a valve tube. The valve body may include a first void and a second void. The inlet component may be coupled to the first void and the outlet component may be coupled to the second void. The valve tube may include a side port and may be positioned through the valve body and coupled to the first void, the inlet component, the second void, and the outlet component. Other valve system examples may include including a valve body, a first septum, a second septum, a first piston, a second piston and a tube. The disclosed methods describe the interaction of the respective components of the respective valve system example.

公开(公告)号：US11684713B2

公开(公告)日：2023-06-27

申请号：US16796853

申请日：2020-02-20

Applicant: Insulet Corporation

Inventor： Steven Diianni ,  Ian McLaughlin ,  Jason O'Connor ,  Robert Campbell ,  Kevin Schmid

IPC: A61M5/145 ,  A61B5/145 ,  A61B5/1486 ,  A61M5/142 ,  F04B9/02 ,  A61M5/172 ,  A61M5/158 ,  A61M5/32 ,  A61M5/14

CPC classification number: A61M5/14566 ,  A61B5/14532 ,  A61B5/14865 ,  A61M5/1452 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/158 ,  A61M5/1723 ,  F04B9/02 ,  A61M5/3291 ,  A61M2005/1403 ,  A61M2005/14252 ,  A61M2005/14506 ,  A61M2230/201 ,  F04C2270/041

Abstract: Disclosed is a fluid delivery device including a fluid reservoir and a transcutaneous access tool fluidly coupled to the fluid reservoir, wherein the transcutaneous access tool includes a needle or a trocar. The fluid delivery device may further include a transcutaneous access tool insertion mechanism for deploying the transcutaneous access tool, wherein the insertion mechanism is configured to insert and retract the needle/trocar in a single, uninterrupted motion.

公开(公告)号：US11551802B2

公开(公告)日：2023-01-10

申请号：US16787223

申请日：2020-02-11

Applicant: INSULET CORPORATION

Inventor： David Nazzaro ,  Steven Cardinali ,  Nicholas Conte ,  Daniel Allis ,  Jason O'Connor ,  Joon Bok Lee ,  Ashutosh Zade ,  Timothy Henning ,  Thomas Metzmaker ,  Ian McLaughlin

IPC: G16H20/60 ,  G16H20/17

Abstract: Disclosed are examples of a device, a system, methods and computer-readable medium products operable to implement functionality to determine and respond to a purpose of a meal. An algorithm or application may receive data that may include data related to a meal purpose from data sources and determine whether any of the data received from the plurality of data sources was received from a direct data source or an indirect data source. The data may be evaluated to determine a purpose of the meal. Based on the results of the evaluation, instructions may be generated to provide an appropriate response based on the determined purpose of the meal. The generated instructions to provide the appropriate response based on the determined purpose of the meal may be output.

公开(公告)号：US11446435B2

公开(公告)日：2022-09-20

申请号：US16697920

申请日：2019-11-27

Applicant: Insulet Corporation

Inventor： Steven Cardinali ,  Lucas McGahren ,  Nicholas Lau ,  Ian McLaughlin

IPC: A61M5/168 ,  A61M5/142 ,  A61M5/145

Abstract: A multiple pulse volume shuttle pump powered by a shape memory alloy (SMA) wire is disclosed. In some embodiments, a shuttle pump system may include a pump chamber, a valve operable with the pump chamber, and a wire coupled to a valve shaft of the valve for controlling a position of the valve. The shuttle pump system may further include a pin disposed within an inset pathway of a cam, wherein the pin is moveable between multiple positions of the inset pathway in response to actuation of the valve shaft.