公开(公告)号：US11280327B2

公开(公告)日：2022-03-22

申请号：US16054323

申请日：2018-08-03

Applicant: Insulet Corporation

Inventor： Daniel Allis ,  Ian McLaughlin ,  Kenneth Phillips

IPC: F04B19/00 ,  F04B1/02 ,  F04B53/10 ,  F04B1/047 ,  F04B1/0452 ,  F04B7/00 ,  F04B9/06 ,  F04B19/22 ,  F04B23/02

Abstract: A low-force, non-displacement, micro/miniature valve and/or pump assembly is provided. A tube component having a first side port coupled to an inlet portion and a second side port coupled to an outlet portion can be selectively moved to alternatively couple the side ports to a first or second piston pump chamber. First and second pistons can be actuated after positioning the tube component to either draw in fluid or push out fluid from either the first or second piston pump chambers during each actuation of the pistons. The fluid can be drawn in from a reservoir and can be expelled to a patient for providing a dose of the fluid to the patient.

公开(公告)号：US11746765B2

公开(公告)日：2023-09-05

申请号：US17667135

申请日：2022-02-08

Applicant: Insulet Corporation

Inventor： Daniel Allis ,  Ian McLaughlin ,  Kenneth Phillips

IPC: F04B19/00 ,  F04B1/02 ,  F04B53/10 ,  F04B1/047 ,  F04B1/0452 ,  F04B7/00 ,  F04B9/06 ,  F04B19/22 ,  F04B23/02

CPC classification number: F04B19/006 ,  F04B1/02 ,  F04B1/047 ,  F04B1/0452 ,  F04B7/003 ,  F04B7/0026 ,  F04B7/0049 ,  F04B7/0053 ,  F04B7/0096 ,  F04B9/06 ,  F04B19/22 ,  F04B23/02 ,  F04B53/109

Abstract: A low-force, non-displacement, micro/miniature valve and/or pump assembly is provided. A tube component having a first side port coupled to an inlet portion and a second side port coupled to an outlet portion can be selectively moved to alternatively couple the side ports to a first or second piston pump chamber. First and second pistons can be actuated after positioning the tube component to either draw in fluid or push out fluid from either the first or second piston pump chambers during each actuation of the pistons. The fluid can be drawn in from a reservoir and can be expelled to a patient for providing a dose of the fluid to the patient.

公开(公告)号：US11090434B2

公开(公告)日：2021-08-17

申请号：US17079393

申请日：2020-10-23

Applicant: Insulet Corporation

Inventor： Jason O'Connor ,  Daniel Allis ,  David Nazzaro ,  John R. Bussiere ,  John D'Arco

IPC: A61M5/172 ,  G16H40/63 ,  G16H20/17 ,  A61M5/142

Abstract: Systems and methods for automatically delivering medication to a user. An automated drug delivery system may include a sensor and a wearable automated drug delivery device. The wearable automated drug delivery device may be configured to couple to the skin of a user and may include a controller and a pump. The pump may be configured to output the medication. The controller may be within the wearable automated drug delivery device. The sensor may be coupled to the user and may be configured to collect information regarding the user. The controller of the wearable automated drug delivery device may use the collected information to locally determine an amount of medication to be output from the wearable automated drug delivery device and cause delivery of the amount of medication.

公开(公告)号：US12090498B2

公开(公告)日：2024-09-17

申请号：US17820703

申请日：2022-08-18

Applicant: INSULET CORPORATION

Inventor： Soroush Kamrava ,  Daniel Allis

IPC: B05B11/10 ,  A61M5/142 ,  F04B43/02 ,  G01N30/32

CPC classification number: B05B11/10 ,  A61M5/142 ,  F04B43/02 ,  G01N2030/326

Abstract: Disclosed herein are various embodiments of a pump mechanism comprising a rigid structure having an open end and a closed end, a plunger disposed in the open end of the rigid structure, and a flexible, fluid-proof sheet of material attached to an inner wall of the rigid structure and bonded to the head of the plunger such as to form a fluid barrier between the interior of the rigid structure and the plunger. Movement of the plunger toward the closed end of the rigid structure causes a rolling corner to be formed between the head of the plunger and the rigid structure and a fluid contained within the pump chamber to be forced out of the pump chamber via a fluid port defined in the closed end of the rigid structure.

公开(公告)号：US11724027B2

公开(公告)日：2023-08-15

申请号：US16884802

申请日：2020-05-27

Applicant: Insulet Corporation

Inventor： Daniel Allis ,  Kenneth Phillips ,  Jacob Anthony Coumans

IPC: A61M5/168 ,  G16H20/17 ,  A61M5/142 ,  A61M5/145

CPC classification number: A61M5/16854 ,  A61M5/1452 ,  A61M5/14248 ,  A61M5/16831 ,  G16H20/17 ,  A61M2005/14264 ,  A61M2005/16863 ,  A61M2205/18 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/3379 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/70

Abstract: A wearable drug delivery device for monitoring unintended over-delivery and/or under-delivery of a stored liquid drug are provided. An absolute pressure sensor can be positioned within the fluid path of the drug delivery device. The absolute pressor sensor can detect both ambient pressure (e.g., absolute or atmospheric pressure) and relative pressure (gage or pumping pressure). Based on the detected pressures, the effects of external ambient pressure on air with the fluid path can be determined during both intended drug delivery events and unintended drug delivery events. In turn, under-delivery and/or over-delivery of the liquid drug can be determined. Based on the severity of the determined under-delivery or over-delivery of the liquid drug, alarms indicating different urgencies can be provided to the user.

公开(公告)号：US11672917B2

公开(公告)日：2023-06-13

申请号：US17039570

申请日：2020-09-30

Applicant: Insulet Corporation

Inventor： Steven Cardinali ,  David Nazzaro ,  Daniel Allis ,  Maureen McCaffrey

IPC: A61M5/315

CPC classification number: A61M5/31576 ,  A61M5/315 ,  A61M5/31501 ,  A61M5/31535 ,  A61M5/31566 ,  A61M5/31593 ,  A61M5/31511 ,  A61M5/31533 ,  A61M5/31543

Abstract: Drive systems for a drug delivery device are provided. The drive systems can be positioned within a container that stores a liquid drug to be delivered to a user. The drive systems can be coupled to a plunger positioned within the container. The drive systems can be incrementally advanced to drive the plunger further into the container, thereby expelling a portion of the stored liquid drug from the container for delivery to the user. The container can be any type of container including a pre-filled, standardized drug cartridge. The drive systems and container can be components of a wearable drug delivery device.

公开(公告)号：US10716896B2

公开(公告)日：2020-07-21

申请号：US15359187

申请日：2016-11-22

Applicant: INSULET CORPORATION

Inventor： Jason O'Connor ,  Daniel Allis ,  David Nazzaro ,  John R. Bussiere ,  John D'Arco

IPC: A61M5/172 ,  G16H40/63 ,  G16H20/17 ,  A61M5/142 ,  G06F19/00

Abstract: Systems and methods for automatically delivering medication to a user. A sensor coupled to a user can collect information regarding the user. A controller can use the collected information to determine an amount of medication to provide the user. The controller can instruct a drug delivery device to dispense the medication to the user. The drug delivery device can be a wearable insulin pump that is directly coupled to the user. The controller can be part of or implemented in a cellphone. A user can be required to provide a confirmation input to allow a determined amount of insulin to be provided to the user based on detected glucose levels of the user. The sensor, controller, and drug delivery device can communicate wirelessly.

公开(公告)号：US12246160B2

公开(公告)日：2025-03-11

申请号：US17552407

申请日：2021-12-16

Applicant: Insulet Corporation

Inventor： Steven Cardinali ,  Daniel Allis ,  Ian Hanson ,  Maureen McCaffrey ,  Chris Goetchius

IPC: A61M5/142 ,  A61M5/145 ,  F04B17/03

Abstract: Examples of fluid delivery drive system and/or pump system that creates a vacuum in a fluid line for drawing and expelling fluid are provided. The vacuum may be created by separating two components that are positioned within the sealed fluid line. Once the two components are separated and the fluid is contained within the volume created between the separated components, the two components may be shuttled within the sealed volume. The movement of the two components can seal off an inlet to the fluid line and then open a pathway to an outlet from the fluid line while ensuring the created volume between the two components is maintained constant. The two components can then be moved back together to expel the fluid from the created volume through the outlet for delivery, for example, to a patient. Other examples are disclosed and described.

公开(公告)号：US11786668B2

公开(公告)日：2023-10-17

申请号：US16140165

申请日：2018-09-24

Applicant: Insulet Corporation

Inventor： David Nazzaro ,  Ian McLaughlin ,  Jeff Barnes ,  Daniel Allis

IPC: A61M5/315 ,  A61M5/32 ,  A61M5/24 ,  A61M5/142 ,  A61M5/145

CPC classification number: A61M5/31565 ,  A61M5/1454 ,  A61M5/14248 ,  A61M5/2455 ,  A61M5/3287 ,  A61M2005/14252 ,  A61M2005/14268 ,  A61M2005/14506 ,  A61M2005/31518

Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can include a spring coupled to a plurality of force transfer elements. The force transfer elements can have a variety of shapes and configurations.

公开(公告)号：US11725741B2

公开(公告)日：2023-08-15

申请号：US16514183

申请日：2019-07-17

Applicant: Insulet Corporation

Inventor： Ian McLaughlin ,  Daniel Allis

IPC: F16K11/07 ,  F16K99/00 ,  G05D7/01 ,  A61M5/142 ,  A61M39/22

CPC classification number: F16K11/0716 ,  A61M5/14216 ,  A61M39/223 ,  F16K99/0011 ,  F16K99/0057 ,  G05D7/0153 ,  A61M2039/224 ,  F16K2099/0086

Abstract: Disclosed are examples of valve systems and methods of operating the respective valve systems. An example valve system may include a valve body, an inlet component, an outlet component and a valve tube. The valve body may include a first void and a second void. The inlet component may be coupled to the first void and the outlet component may be coupled to the second void. The valve tube may include a side port and may be positioned through the valve body and coupled to the first void, the inlet component, the second void, and the outlet component. Other valve system examples may include including a valve body, a first septum, a second septum, a first piston, a second piston and a tube. The disclosed methods describe the interaction of the respective components of the respective valve system example.