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公开(公告)号：US20100286496A1
公开(公告)日：2010-11-11
申请号：US12838691
申请日：2010-07-19
申请人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathburn K. Rhodes , Mark A. Tapsak
发明人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathburn K. Rhodes , Mark A. Tapsak
IPC分类号： A61B5/1473
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1495 , A61B5/7203 , A61B5/742 , A61B2560/0223 , B33Y70/00 , B33Y80/00
摘要： Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.
摘要翻译： 本文公开了用于连续分析物传感器（例如连续葡萄糖传感器）的系统和方法。 一个这样的系统利用第一和第二工作电极来测量分析物或非分析物相关的信号，这两个电极都包括干涉域。
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公开(公告)号：US07693560B2
公开(公告)日：2010-04-06
申请号：US11692154
申请日：2007-03-27
申请人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathburn K. Rhodes , Mark A. Tapsak
发明人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathburn K. Rhodes , Mark A. Tapsak
IPC分类号： A61B5/00
摘要： Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.
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公开(公告)号：US08255033B2
公开(公告)日：2012-08-28
申请号：US11410392
申请日：2006-04-25
CPC分类号： A61B5/1473 , A61B5/145 , A61B5/14503 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/14735 , A61B5/14865
摘要： The present invention relates generally to systems and methods for increasing oxygen availability to implantable devices. The preferred embodiments provide a membrane system configured to provide protection of the device from the biological environment and/or a catalyst for enabling an enzymatic reaction, wherein the membrane system includes a polymer formed from a high oxygen soluble material. The high oxygen soluble polymer material is disposed adjacent to an oxygen-utilizing source on the implantable device so as to dynamically retain high oxygen availability to the oxygen-utilizing source during oxygen deficits. Membrane systems of the preferred embodiments are useful for implantable devices with oxygen-utilizing sources and/or that function in low oxygen environments, such as enzyme-based electrochemical sensors and cell transplantation devices.
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公开(公告)号：US08255030B2
公开(公告)日：2012-08-28
申请号：US11410555
申请日：2006-04-25
CPC分类号： A61B5/1473 , A61B5/145 , A61B5/14503 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/14735 , A61B5/14865
摘要： The present invention relates generally to systems and methods for increasing oxygen availability to implantable devices. The preferred embodiments provide a membrane system configured to provide protection of the device from the biological environment and/or a catalyst for enabling an enzymatic reaction, wherein the membrane system includes a polymer formed from a high oxygen soluble material. The high oxygen soluble polymer material is disposed adjacent to an oxygen-utilizing source on the implantable device so as to dynamically retain high oxygen availability to the oxygen-utilizing source during oxygen deficits. Membrane systems of the preferred embodiments are useful for implantable devices with oxygen-utilizing sources and/or that function in low oxygen environments, such as enzyme-based electrochemical sensors and cell transplantation devices.
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公开(公告)号：US07761130B2
公开(公告)日：2010-07-20
申请号：US11692154
申请日：2007-03-27
申请人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathbun K. Rhodes , Mark A. Tapsak
发明人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathbun K. Rhodes , Mark A. Tapsak
IPC分类号： A61B5/00
CPC分类号： A61B5/1495 , A61B5/14532 , A61B5/14865 , B33Y70/00
摘要： Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.
摘要翻译： 本文公开了用于连续分析物传感器（例如连续葡萄糖传感器）的系统和方法。 一个这样的系统利用第一和第二工作电极来测量分析物或非分析物相关的信号，这两个电极都包括干涉域。
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公开(公告)号：US20090076356A1
公开(公告)日：2009-03-19
申请号：US12264160
申请日：2008-11-03
申请人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathburn K. Rhodes , Mark A. Tapsak
发明人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathburn K. Rhodes , Mark A. Tapsak
IPC分类号： A61B5/145
CPC分类号： A61B5/1495 , A61B5/14532 , A61B5/14865 , B33Y70/00
摘要： Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.
摘要翻译： 本文公开了用于连续分析物传感器（例如连续葡萄糖传感器）的系统和方法。 一个这样的系统利用第一和第二工作电极来测量分析物或非分析物相关的信号，这两个电极都包括干涉域。
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公开(公告)号：US08483793B2
公开(公告)日：2013-07-09
申请号：US12916289
申请日：2010-10-29
申请人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathburn K. Rhodes , Mark A. Tapsak
发明人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathburn K. Rhodes , Mark A. Tapsak
IPC分类号： A61B5/05
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1495 , A61B5/7203 , A61B5/742 , A61B2560/0223 , B33Y70/00 , B33Y80/00
摘要： Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.
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公开(公告)号：US20110046467A1
公开(公告)日：2011-02-24
申请号：US12916289
申请日：2010-10-29
申请人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathburn K. Rhodes , Mark A. Tapsak
发明人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathburn K. Rhodes , Mark A. Tapsak
IPC分类号： A61B5/1473
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1495 , A61B5/7203 , A61B5/742 , A61B2560/0223 , B33Y70/00 , B33Y80/00
摘要： Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.
摘要翻译： 本文公开了用于连续分析物传感器（例如连续葡萄糖传感器）的系统和方法。 一个这样的系统利用第一和第二工作电极来测量分析物或非分析物相关的信号，这两个电极都包括干涉域。
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公开(公告)号：US07828728B2
公开(公告)日：2010-11-09
申请号：US11675063
申请日：2007-02-14
申请人： Robert Boock , Monica Rixman , James H. Brauker , James R. Petisce , Peter C. Simpson , Mark Brister , Mark A. Tapsak , Victoria Carr-Brendel
发明人： Robert Boock , Monica Rixman , James H. Brauker , James R. Petisce , Peter C. Simpson , Mark Brister , Mark A. Tapsak , Victoria Carr-Brendel
CPC分类号： A61B5/14865 , A61B5/0031 , A61B5/14532 , A61B5/418 , B33Y70/00
摘要： The present invention relates generally to membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the invention relates to novel silicone-hydrophilic polymer blend membranes, and to devices and implantable devices including these membranes.
摘要翻译： 本发明一般涉及与可植入装置一起使用的膜，例如用于检测生物样品中分析物浓度的装置。 更具体地说，本发明涉及新的有机硅 - 亲水性聚合物共混膜，以及包括这些膜的装置和可植入装置。
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公开(公告)号：US20100145172A1
公开(公告)日：2010-06-10
申请号：US12688763
申请日：2010-01-15
IPC分类号： A61B5/1468
CPC分类号： A61B5/1473 , A61B5/145 , A61B5/14503 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/14735 , A61B5/14865
摘要： The present invention relates generally to systems and methods for increasing oxygen availability to implantable devices. The preferred embodiments provide a membrane system configured to provide protection of the device from the biological environment and/or a catalyst for enabling an enzymatic reaction, wherein the membrane system includes a polymer formed from a high oxygen soluble material. The high oxygen soluble polymer material is disposed adjacent to an oxygen-utilizing source on the implantable device so as to dynamically retain high oxygen availability to the oxygen-utilizing source during oxygen deficits. Membrane systems of the preferred embodiments are useful for implantable devices with oxygen-utilizing sources and/or that function in low oxygen environments, such as enzyme-based electrochemical sensors and cell transplantation devices.
摘要翻译： 本发明一般涉及用于增加可植入装置的氧气可用性的系统和方法。 优选的实施方案提供了一种膜系统，其被配置为提供该装置与生物环境的保护和/或用于实现酶反应的催化剂，其中所述膜系统包括由高氧可溶性材料形成的聚合物。 高氧可溶性聚合物材料与可植入装置上的氧气源相邻设置，以便在缺氧期间动态地保持氧利用源的高氧可利用性。 优选实施方案的膜系统对于具有氧利用源的可植入装置和/或在低氧环境中起作用，例如基于酶的电化学传感器和细胞移植装置是有用的。
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