摘要:
The invention provides methods for sequencing a polynucleotide comprising stopping an extension cycle in a sequence by synthesis reaction before the reaction has run to near or full completion.
摘要:
The invention provides methods for sequencing polynucleotide molecules using single molecule sequencing techniques, where a plurality of labeled nucleotides are incorporated consecutively into an individual primer molecule.
摘要:
In one aspect the invention relates to an apparatus for analyzing the presence of a single molecule using total internal reflection. In one embodiment an apparatus for single molecule analysis includes a support having a sample located thereon; two sources of light at distinct wavelengths, a collimator for directing the light onto the sample through a total internal reflection objective; a receiver for receiving a fluorescent emission produced by a single molecule in the sample in response to the light; and a detector for detecting each of the wavelengths in the fluorescent emission. In another embodiment the apparatus further comprises a focusing laser for maintaining focus of the objective on the sample.
摘要:
The invention provides methods for sequencing a polynucleotide comprising stopping an extension cycle in a sequence by synthesis reaction before the reaction has run to near or full completion.
摘要:
A multi-core processor with a shared physical memory is described. In an embodiment a sending core sends a memory write request to a destination core so that the request may be acted upon by the destination core as if it originated from the destination core. In an example, a data structure is configured in the shared physical memory and mapped to be accessible to the sending and destination cores. In an example, the shared data structure is used as a message channel between the sending and destination cores to carry data using the memory write request. In an embodiment a notification mechanism is enabled using the shared physical memory in order to notify the destination core of events by updating a notification data structure. In an example, the notification mechanism triggers a notification process at the destination core to inform a receiving process of a notification.
摘要:
A multi-core processor with a shared physical memory is described. In an embodiment a sending core sends a memory write request to a destination core so that the request may be acted upon by the destination core as if it originated from the destination core. In an example, a data structure is configured in the shared physical memory and mapped to be accessible to the sending and destination cores. In an example, the shared data structure is used as a message channel between the sending and destination cores to carry data using the memory write request. In an embodiment a notification mechanism is enabled using the shared physical memory in order to notify the destination core of events by updating a notification data structure. In an example, the notification mechanism triggers a notification process at the destination core to inform a receiving process of a notification.
摘要:
A method of optimizing code which invokes methods on a system across an interface is described. High level information relating to the system is accessed and this information is used in performing code transformations in order to optimize the code.
摘要:
A transactional memory system is described for reporting memory access violations which occur when memory accesses made from instructions within a transaction conflict with memory accesses to the same memory location made from a non-transactional instruction. In an embodiment this is achieved by creating two mappings of a physical heap being used by a thread. The thread (which may be part of a multi-threaded process) comprises instructions for both transactional and non-transactional accesses to the physical heap which may execute concurrently as part of that thread. One of the mappings is used for non-transactional memory accesses to the physical heap. The other mapping is used for transactional memory accesses to the physical heap. Access permissions associated with the mappings are controlled to enable attempted memory access violations to be detected and reported.
摘要:
The invention provides methods for sequencing a polynucleotide comprising stopping an extension cycle in a sequence by synthesis reaction before the reaction has run to near or full completion.
摘要:
The invention provides methods for sequencing a polynucleotide comprising stopping an extension cycle in a sequence by synthesis reaction before the reaction has run to near or full completion.