Optical train and method for TIRF single molecule detection and analysis
    33.
    发明申请
    Optical train and method for TIRF single molecule detection and analysis 审中-公开
    光学列车和TIRF单分子检测与分析方法

    公开(公告)号:US20070070349A1

    公开(公告)日:2007-03-29

    申请号:US11234420

    申请日:2005-09-23

    IPC分类号: G01N21/64

    摘要: In one aspect the invention relates to an apparatus for analyzing the presence of a single molecule using total internal reflection. In one embodiment an apparatus for single molecule analysis includes a support having a sample located thereon; two sources of light at distinct wavelengths, a collimator for directing the light onto the sample through a total internal reflection objective; a receiver for receiving a fluorescent emission produced by a single molecule in the sample in response to the light; and a detector for detecting each of the wavelengths in the fluorescent emission. In another embodiment the apparatus further comprises a focusing laser for maintaining focus of the objective on the sample.

    摘要翻译: 一方面,本发明涉及一种使用全内反射来分析单个分子的存在的装置。 在一个实施方案中,用于单分子分析的装置包括具有位于其上的样品的载体; 两个不同波长的光源,用于通过全内反射物镜将光引导到样品上的准直器; 接收器,用于响应于光接收由样品中的单个分子产生的荧光发射; 以及用于检测荧光发射中的每个波长的检测器。 在另一个实施例中,该装置还包括聚焦激光器,用于保持物体在样本上的焦点。

    Remote core operations in a multi-core computer
    35.
    发明授权
    Remote core operations in a multi-core computer 有权
    多核计算机中的远程核心操作

    公开(公告)号:US09471532B2

    公开(公告)日:2016-10-18

    申请号:US13025446

    申请日:2011-02-11

    摘要: A multi-core processor with a shared physical memory is described. In an embodiment a sending core sends a memory write request to a destination core so that the request may be acted upon by the destination core as if it originated from the destination core. In an example, a data structure is configured in the shared physical memory and mapped to be accessible to the sending and destination cores. In an example, the shared data structure is used as a message channel between the sending and destination cores to carry data using the memory write request. In an embodiment a notification mechanism is enabled using the shared physical memory in order to notify the destination core of events by updating a notification data structure. In an example, the notification mechanism triggers a notification process at the destination core to inform a receiving process of a notification.

    摘要翻译: 描述了具有共享物理内存的多核处理器。 在一个实施例中,发送核心向目的地核心发送存储器写入请求,使得请求可以被目的地核心作为来自目的地核心的动作。 在一个示例中,在共享物理内存中配置数据结构,并将其映射到发送和目标内核可访问。 在一个示例中,共享数据结构被用作发送和目的地核心之间的消息通道,以使用存储器写入请求携带数据。 在一个实施例中,使用共享物理存储器启用通知机制,以通过更新通知数据结构来通知目的地核心的事件。 在一个示例中,通知机制触发目的地核心处的通知处理,以通知接收进程通知。

    Remote Core Operations In A Multi-Core Computer
    36.
    发明申请
    Remote Core Operations In A Multi-Core Computer 有权
    多核计算机中的远程核心操作

    公开(公告)号:US20120210071A1

    公开(公告)日:2012-08-16

    申请号:US13025446

    申请日:2011-02-11

    IPC分类号: G06F12/08 G06F12/10

    摘要: A multi-core processor with a shared physical memory is described. In an embodiment a sending core sends a memory write request to a destination core so that the request may be acted upon by the destination core as if it originated from the destination core. In an example, a data structure is configured in the shared physical memory and mapped to be accessible to the sending and destination cores. In an example, the shared data structure is used as a message channel between the sending and destination cores to carry data using the memory write request. In an embodiment a notification mechanism is enabled using the shared physical memory in order to notify the destination core of events by updating a notification data structure. In an example, the notification mechanism triggers a notification process at the destination core to inform a receiving process of a notification.

    摘要翻译: 描述了具有共享物理内存的多核处理器。 在一个实施例中,发送核心向目的地核心发送存储器写入请求,使得请求可以被目的地核心作为来自目的地核心的动作。 在一个示例中,在共享物理内存中配置数据结构,并将其映射到发送和目标内核可访问。 在一个示例中,共享数据结构被用作发送和目的地核心之间的消息通道,以使用存储器写入请求携带数据。 在一个实施例中,使用共享物理存储器启用通知机制,以通过更新通知数据结构来通知目的地核心的事件。 在一个示例中,通知机制触发目的地核心处的通知处理,以通知接收进程通知。

    Memory conflict detection via mapping of the physical heap to control access permissions to the memory
    38.
    发明授权
    Memory conflict detection via mapping of the physical heap to control access permissions to the memory 有权
    通过物理堆映射来检测内存冲突,以控制对内存的访问权限

    公开(公告)号:US08180986B2

    公开(公告)日:2012-05-15

    申请号:US12212025

    申请日:2008-09-17

    IPC分类号: G06F12/00

    CPC分类号: G06F12/145 G06F9/528

    摘要: A transactional memory system is described for reporting memory access violations which occur when memory accesses made from instructions within a transaction conflict with memory accesses to the same memory location made from a non-transactional instruction. In an embodiment this is achieved by creating two mappings of a physical heap being used by a thread. The thread (which may be part of a multi-threaded process) comprises instructions for both transactional and non-transactional accesses to the physical heap which may execute concurrently as part of that thread. One of the mappings is used for non-transactional memory accesses to the physical heap. The other mapping is used for transactional memory accesses to the physical heap. Access permissions associated with the mappings are controlled to enable attempted memory access violations to be detected and reported.

    摘要翻译: 描述了一种事务性存储器系统,用于报告存储器访问冲突的发生,当由事务内的指令进行的存储器访问与从非事务性指令进行的存储器访问的存储器访问冲突时发生。 在一个实施例中,这是通过创建由线程使用的物理堆的两个映射来实现的。 线程(可以是多线程进程的一部分)包括用于对物理堆的事务和非事务性访问的指令,该物理堆可以作为该线程的一部分同时执行。 其中一个映射用于对物理堆的非事务内存访问。 另一个映射用于对物理堆的事务内存访问。 控制与映射关联的访问权限,以便检测和报告尝试的内存访问冲突。