Forming closely spaced electrodes
    31.
    发明申请
    Forming closely spaced electrodes 有权
    形成紧密间隔的电极

    公开(公告)号:US20050014357A1

    公开(公告)日:2005-01-20

    申请号:US10803244

    申请日:2004-03-18

    摘要: The present invention provides an apparatus and a method of fabricating the apparatus. The apparatus comprises a substrate having a planar surface and first and second electrodes located on the planar surface. The first electrode has a top surface and a lateral surface, and the lateral surface has an edge near or in contact with the substrate. An electrode insulating layer is located on the top surface and a self-assembled layer located on the lateral surface. The second electrode is in contact with both the self-assembled layer and the electrode insulating layer.

    摘要翻译: 本发明提供一种制造该装置的装置和方法。 该装置包括具有平坦表面的基底和位于平坦表面上的第一和第二电极。 第一电极具有顶表面和侧表面,并且侧表面具有与基底接近或接触的边缘。 电极绝缘层位于顶表面上,并且位于侧表面上的自组装层。 第二电极与自组装层和电极绝缘层接触。

    Wheel chock
    32.
    外观设计

    公开(公告)号:USD971812S1

    公开(公告)日:2022-12-06

    申请号:US29833310

    申请日:2022-04-02

    申请人: Jie Zheng

    设计人: Jie Zheng

    LUMINESCENT NANOPARTICLE COMPOSITIONS
    33.
    发明申请
    LUMINESCENT NANOPARTICLE COMPOSITIONS 有权
    发光纳米颗粒组合物

    公开(公告)号:US20140193837A1

    公开(公告)日:2014-07-10

    申请号:US14124057

    申请日:2012-06-14

    申请人: Jie Zheng

    发明人: Jie Zheng

    IPC分类号: G01N33/58

    摘要: A composition is disclosed which is capable of being used for detection, comprising a noble metal nanoparticle. The inventive compositions exhibit little interaction with serum proteins while exhibiting pH-dependent adsorption onto live cell membranes. The nanoparticles of the claimed invention are capable of interacting with cell membranes, which in turn permits the advantages of nanoparticle bio-imaging to be extended to many pH dependent biological processes such as targeting acidic tumor microenvironment.

    摘要翻译: 公开了能够用于检测的组合物,其包含贵金属纳米颗粒。 本发明的组合物与血清蛋白质几乎没有相互作用,同时在活细胞膜上显示pH依赖性吸附。 所要求保护的发明的纳米颗粒能够与细胞膜相互作用,这反过来允许纳米颗粒生物成像的优点扩展到许多pH依赖性生物过程,例如靶向酸性肿瘤微环境。

    Task prioritization management in a virtualized environment
    34.
    发明授权
    Task prioritization management in a virtualized environment 有权
    虚拟化环境中的任务优先级管理

    公开(公告)号:US08756599B2

    公开(公告)日:2014-06-17

    申请号:US13007895

    申请日:2011-01-17

    IPC分类号: G06F9/455 G06F9/50

    CPC分类号: G06F9/45533 G06F9/5077

    摘要: A method, computer program product, and system for managing tasks for a virtual machine are presented. An amount of resources to perform a task for the virtual machine are identified in response to receiving a request to perform the task for the virtual machine in a set of data processing systems. A set of resources in the set of data processing systems available to complete the task for the virtual machine are identified. A set of priorities for a set of phases of the task are identified. Operations are scheduled on the set of resources to perform the task for the virtual machine based on the set of priorities identified for the set of phases of the task.

    摘要翻译: 提出了一种用于管理虚拟机的任务的方法,计算机程序产品和系统。 响应于在一组数据处理系统中接收到执行虚拟机的任务的请求来识别用于执行虚拟机的任务的资源的量。 识别可用于完成虚拟机任务的一组数据处理系统中的一组资源。 确定了一系列任务阶段的优先事项。 根据为任务的一组阶段确定的优先级集合,在该组资源上安排操作以执行虚拟机的任务。

    METHOD OF COATING A PART OF A HEAT EXCHANGER AND HEAT EXCHANGER
    35.
    发明申请
    METHOD OF COATING A PART OF A HEAT EXCHANGER AND HEAT EXCHANGER 审中-公开
    热交换器和热交换器的一部分涂覆方法

    公开(公告)号:US20130248157A1

    公开(公告)日:2013-09-26

    申请号:US13990365

    申请日:2011-11-30

    申请人: Jie Zheng

    发明人: Jie Zheng

    IPC分类号: F28F19/06 F28F21/08

    摘要: A method of coating an internal surface of an assembled heat exchanger is provided. The heat exchanger comprising a first passage for a first heat exchange fluid, and a second passage for a second heat exchange fluid. The first and second passages are separated by at least one heat transfer element. The heat transfer element has a first surface facing the first passage. The method comprises; pre-treating the first surface by circulating at least one pre-treatment liquid through the first passage of the heat exchanger and a pre-treatment liquid storage separate from the heat exchanger, and electroless nickel plating the first surface by circulating a solution comprising nickel ions through the first passage of the heat exchanger and a solution container separate from the heat exchanger. A heat exchanger comprising a nickel plating is also disclosed.

    摘要翻译: 提供了一种涂覆组装的热交换器的内表面的方法。 所述热交换器包括用于第一热交换流体的第一通道和用于第二热交换流体的第二通道。 第一和第二通道被至少一个传热元件隔开。 传热元件具有面向第一通道的第一表面。 该方法包括: 通过使热交换器的第一通道循环至少一个预处理液体和与热交换器分离的预处理液体储存器来预处理第一表面,以及通过使包含镍离子的溶液循环来无电镀镍第一表面 通过热交换器的第一通道和与热交换器分离的溶液容器。 还公开了一种包括镀镍的热交换器。

    Prokaryotic expression of soluble, active Dkk
    36.
    发明授权
    Prokaryotic expression of soluble, active Dkk 失效
    可溶性,活性Dkk的原核表达

    公开(公告)号:US08470554B2

    公开(公告)日:2013-06-25

    申请号:US13133474

    申请日:2009-12-18

    申请人: Jie Zheng

    发明人: Jie Zheng

    CPC分类号: C07K14/4718

    摘要: Dickkopf (Dkk) proteins inhibit the canonical Wnt signaling pathway. Each of the members of the Dkk family has been previously cloned and expressed as a soluble protein in eukaryotic cells, while expression in bacterial cells has resulted in the formation of insoluble inclusion bodies that require further processing. The present invention provides compositions and methods for producing soluble, active dkk protein in prokaryotic host cells, by expressing the dkk protein as a fusion protein with a solubilization molecule, thereby providing an inexpensive and convenient source of pure active Dkk.

    摘要翻译: Dickkopf(Dkk)蛋白抑制规范的Wnt信号通路。 Dkk家族的每个成员之前已被克隆并在真核细胞中表达为可溶性蛋白质,而在细菌细胞中的表达导致需要进一步处理的不溶性包涵体的形成。 本发明提供了通过用溶解分子表达作为融合蛋白的dkk蛋白质,从而提供廉价且方便的纯活性Dkk来源,从而在原核宿主细胞中生产可溶性活性dkk蛋白质的组合物和方法。

    DIAMOND METAL COMPOSITE
    37.
    发明申请
    DIAMOND METAL COMPOSITE 有权
    金刚石金属复合材料

    公开(公告)号:US20100279138A1

    公开(公告)日:2010-11-04

    申请号:US12741318

    申请日:2008-10-30

    申请人: Jie Zheng

    发明人: Jie Zheng

    IPC分类号: B32B1/00 B22F3/10 B22F1/00

    摘要: The present invention relates to a method for producing diamond-metal composites comprising mixing diamond particles with metal-filler particles forming a diamond/metal-filler mixture, forming a green body of the diamond/metal-filler mixture, optionally green machining the green body to a work piece before or after pre-sintering by heating the green body to a temperature ≦500° C., infiltrating the green body or the work piece with one or more wetting elements or infiltrating the green body or the work piece with one or more wetting alloys, which infiltration step being carried out under vacuum or in an inert gas atmosphere at a pressure ≦200 Bar. The invention relates further to a green body, a diamond metal composite, and use of the diamond metal composite.

    摘要翻译: 本发明涉及一种生产金刚石 - 金属复合材料的方法,包括将金刚石颗粒与形成金刚石/金属 - 填料混合物的金属 - 填料颗粒混合,形成金刚石/金属 - 填料混合物的生坯,任选地绿色加工生坯 通过将生坯体加热至温度<500℃而在预烧结之前或之后的工件; 500℃,用一种或多种润湿元件渗透生坯或工件,或者用一个或多个润湿元件浸入生坯或工件 或更多润湿合金,该渗透步骤在真空下或在惰性气体气氛中在压力为200巴下进行。 本发明进一步涉及生坯,金刚石金属复合材料和金刚石金属复合材料的用途。

    Forming closely spaced electrodes
    38.
    发明授权
    Forming closely spaced electrodes 有权
    形成紧密间隔的电极

    公开(公告)号:US07569416B2

    公开(公告)日:2009-08-04

    申请号:US11424655

    申请日:2006-06-16

    IPC分类号: H01L21/00

    摘要: The present invention provides an apparatus and a method of fabricating the apparatus. The apparatus comprises a substrate having a planar surface and first and second electrodes located on the planar surface. The first electrode has a top surface and a lateral surface, and the lateral surface has an edge near or in contact with the substrate. An electrode insulating layer is located on the top surface and a self-assembled layer located on the lateral surface. The second electrode is in contact with both the self-assembled layer and the electrode insulating layer.

    摘要翻译: 本发明提供一种制造该装置的装置和方法。 该装置包括具有平坦表面的基底和位于平坦表面上的第一和第二电极。 第一电极具有顶表面和侧表面,并且侧表面具有与基底接近或接触的边缘。 电极绝缘层位于顶表面上,并且位于侧表面上的自组装层。 第二电极与自组装层和电极绝缘层接触。

    GTPase inhibitors and methods of use
    39.
    发明授权
    GTPase inhibitors and methods of use 有权
    GTPase抑制剂和使用方法

    公开(公告)号:US07517890B2

    公开(公告)日:2009-04-14

    申请号:US10994165

    申请日:2004-11-19

    IPC分类号: A61K31/506

    摘要: The preferred embodiments generally relate to methods and compositions that affect the GTP-binding activity of members of the Rho family GTPases, preferably Rac (Rac1, Rac2 and/or Rac3), such compositions include compounds that modulate the GTP/GDP exchange activity, along with uses for the compounds including screening for compounds which recognize Rac GTPase, and methods of treating pathological conditions associated or related to a Rho family GTPase, including Rac. The preferred embodiments also relate to methods of using such compounds, or derivatives thereof, e.g., in therapeutics, diagnostics, and as research tools.

    摘要翻译: 优选的实施方案通常涉及影响Rho家族GTP酶,优选Rac(Rac1,Rac2和/或Rac3)成员的GTP-结合活性的方法和组合物,所述组合物包括调节GTP / GDP交换活性的化合物 用于化合物的用途,包括筛选识别Rac GTP酶的化合物,以及治疗与Rho家族GTP酶(包括Rac)相关或相关的病理状况的方法。 优选实施方案还涉及使用这些化合物或其衍生物的方法,例如在治疗学,诊断学和研究工具中。