公开(公告)号：US20220228686A1

公开(公告)日：2022-07-21

申请号：US17712501

申请日：2022-04-04

Applicant: Life Technologies Corporation

Inventor： Ryan S. Beus ,  Brandon R. Burtenshaw ,  Eric Davis ,  Patrick L. Draper ,  Michael E. Goodwin ,  Brandon M. Knudsen ,  Jeremy K. Larsen ,  Kevin R. Pickup

IPC: F16L33/207 ,  F16L33/22 ,  B29C65/00 ,  B29C65/68 ,  B29C65/56 ,  A61M39/12

Abstract: A coupling assembly includes: a tubular compression collar having a tubular body made of a resiliently flexible polymeric material and having an interior surface and an opposing exterior surface; an end of a tube disposed within a throughway of the compression collar; and a tube fitting disposed within the passageway of the tube. The tube fitting includes: a tubular stem; a flange radially outwardly projecting from an exterior surface of the stem; and an annular barb encircling and radially outwardly projecting from the exterior surface of the stem, the annular barb including a frustoconical outside face that extends along and outwardly slopes away from the stem as the outside face extends toward the flange. The compression collar radially inwardly compresses the tube against the annular barb of the tube fitting so that a liquid tight seal is formed between the tube and the tube fitting.

公开(公告)号：US11148836B2

公开(公告)日：2021-10-19

申请号：US16385775

申请日：2019-04-16

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael E. Goodwin ,  Jeremy K. Larsen ,  Patrick L. Draper ,  Brandon M. Knudsen

IPC: B65B3/00 ,  B65B1/04 ,  B65B3/02 ,  B65B3/04 ,  B65B51/02 ,  B65B51/22 ,  A61J1/10

Abstract: A method of dispensing a fluid includes coupling a manifold to a fluid source, the manifold including at least portions of opposing flexible sheets welded together to form a fluid flow path therebetween; passing a fluid from the fluid source through the fluid flow path of the manifold and into a plurality of flexible bags coupled to the manifold; sealing closed each of the flexible bags; progressively collapsing the fluid flow path along a length of the manifold so as to force a portion of the fluid remaining within the fluid flow path into one of the flexible bags before all of the flexible bags are sealed closed; and removing each sealed bag from the manifold.

公开(公告)号：US20210237011A1

公开(公告)日：2021-08-05

申请号：US17236238

申请日：2021-04-21

Applicant: Life Technologies Corporation

Inventor： Nephi D. Jones ,  Brandon M. Knudsen ,  Whitt F. Woods

IPC: B01F15/00 ,  C12M1/00 ,  B01F7/00 ,  B01F7/16 ,  B01F7/22 ,  B01F11/00 ,  B01F15/02 ,  C12M1/06 ,  C12M3/06 ,  C12M3/00 ,  C12M1/02

Abstract: A method for mixing a fluid includes: dispensing a first volume of a fluid into a flexible container, the flexible container being at least partially disposed within the chamber of a support housing; repeatedly moving the support housing and the flexible container contained therein so as to mix the first volume of fluid within the flexible container; adding further fluid into the flexible container after moving the support housing to form a second volume of fluid; and manipulating a mixing element within the flexible container so as to mix the second volume of fluid.

公开(公告)号：US11020718B2

公开(公告)日：2021-06-01

申请号：US16026771

申请日：2018-07-03

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Nephi D. Jones ,  Brandon M. Knudsen ,  Whitt F. Woods

IPC: B01F15/00 ,  C12M1/00 ,  B01F7/00 ,  B01F7/16 ,  B01F7/22 ,  B01F11/00 ,  B01F15/02 ,  C12M1/06 ,  C12M3/06 ,  C12M3/00 ,  C12M1/02

Abstract: A method for mixing a fluid includes: dispensing a first volume of a fluid into a flexible container, the flexible container being at least partially disposed within the chamber of a support housing; repeatedly moving the support housing and the flexible container contained therein so as to mix the first volume of fluid within the flexible container; adding further fluid into the flexible container after moving the support housing to form a second volume of fluid; and manipulating a mixing element within the flexible container so as to mix the second volume of fluid.

公开(公告)号：US10850243B2

公开(公告)日：2020-12-01

申请号：US16165650

申请日：2018-10-19

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Jeremy K. Larsen ,  Clinton C. Staheli ,  Brandon M. Knudsen

IPC: B01F7/00 ,  B01F7/22 ,  B01F15/00 ,  B01F7/16

Abstract: A fluid mixing system includes a flexible bag having a first end, an opposing second end, and an interior surface bounding a compartment. A first rotational assembly includes a first casing mounted to the first end of the flexible bag and a first hub rotatably mounted to the first casing. A second rotational assembly includes a second casing mounted to the second end of the flexible bag and a second hub rotatably mounted to the second casing. An elongated member has a first end coupled with the first hub and an opposing second end coupled with the second hub, the connector being flexible and having a uniform flexibility along its entire length. A first impeller is mounted to the connector.

公开(公告)号：US20190209981A1

公开(公告)日：2019-07-11

申请号：US16358263

申请日：2019-03-19

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Clinton C. Staheli ,  Brandon M. Knudsen ,  Trevor G. Williams ,  Steven R. Kjar

IPC: B01F7/00 ,  B01F15/00 ,  B01F7/20 ,  C12M1/06 ,  C12M1/00 ,  B01F7/16

CPC classification number: B01F7/00683 ,  B01F7/00058 ,  B01F7/001 ,  B01F7/00158 ,  B01F7/00291 ,  B01F7/00316 ,  B01F7/00633 ,  B01F7/00675 ,  B01F7/1695 ,  B01F7/20 ,  B01F15/00668 ,  B01F15/00681 ,  B01F15/00707 ,  B01F15/0085 ,  C12M23/14 ,  C12M23/52 ,  C12M27/02

Abstract: A fluid mixing system includes a container, such as a flexible bag, bounding a compartment. A flexible drive line is disposed within the compartment, the drive line having a first end rotatably connected to a first end of the container and an opposing second end rotatably connected to a second end of the container. At least one mixing element, such as an impeller, can be coupled with the flexible drive line. Rotation of the drive line facilitates rotation of the impeller within the container.

公开(公告)号：US10308378B2

公开(公告)日：2019-06-04

申请号：US14728717

申请日：2015-06-02

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael E. Goodwin ,  Jeremy K. Larsen ,  Patrick L. Draper ,  Brandon M. Knudsen

IPC: B65B3/04 ,  B65B1/04 ,  B65B3/00 ,  B65B3/02 ,  B65B51/02 ,  B65B51/22 ,  A61J1/10

Abstract: A fluid manifold system includes a manifold having at least portions of opposing flexible sheets welded together to form a fluid flow path therebetween, a fluid inlet communicating with the fluid flow path. A plurality of receiving containers are in fluid communication with the fluid flow path of the manifold, each receiving container bounding a compartment. The receiving containers can be formed integral with the manifold by welding together a second portion of the opposing flexible sheets or can comprise separate containers that are coupled to the manifold.

公开(公告)号：US10272400B2

公开(公告)日：2019-04-30

申请号：US15803327

申请日：2017-11-03

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Clinton C. Staheli ,  Brandon M. Knudsen ,  Trevor G. Williams ,  Steven R. Kjar

IPC: B01F7/16 ,  B01F7/00 ,  B01F7/20 ,  B01F15/00 ,  C12M1/00 ,  C12M1/06

Abstract: A fluid mixing system includes a container, such as a flexible bag, bounding a compartment. A flexible drive line is disposed within the compartment, the drive line having a first end rotatably connected to a first end of the container and an opposing second end rotatably connected to a second end of the container. At least one mixing element, such as an impeller, can be coupled with the flexible drive line. Rotation of the drive line facilitates rotation of the impeller within the container.

公开(公告)号：US09839886B2

公开(公告)日：2017-12-12

申请号：US14390956

申请日：2013-03-14

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Clinton C. Staheli ,  Brandon M. Knudsen ,  Trevor G. Williams ,  Steven R. Kjar

IPC: B01F7/16 ,  B01F7/00 ,  B01F7/20 ,  B01F15/00 ,  C12M1/00 ,  C12M1/06

CPC classification number: B01F7/00683 ,  B01F7/00058 ,  B01F7/001 ,  B01F7/00158 ,  B01F7/00291 ,  B01F7/00316 ,  B01F7/00633 ,  B01F7/00675 ,  B01F7/1695 ,  B01F7/20 ,  B01F15/00668 ,  B01F15/00681 ,  B01F15/00707 ,  B01F15/0085 ,  C12M23/14 ,  C12M23/52 ,  C12M27/02

Abstract: A fluid mixing system includes a container, such as a flexible bag, bounding a compartment. A flexible drive line is disposed within the compartment, the drive line having a first end rotatably connected to a first end of the container and an opposing second end rotatably connected to a second end of the container. At least one mixing element, such as an impeller, is coupled with the flexible drive line. Rotation of the drive line facilitates rotation of the impeller within the container.