公开(公告)号：US20050120410A1

公开(公告)日：2005-06-02

申请号：US10505744

申请日：2003-03-05

申请人： Tesfaye Mengiste ,  Xi Chen ,  John Salmeron ,  Robert Dietrich

发明人： Tesfaye Mengiste ,  Xi Chen ,  John Salmeron ,  Robert Dietrich

IPC分类号： C07K14/415 ,  C12N15/29 ,  C12N15/82 ,  A01H1/00 ,  C07H21/04 ,  C12N9/24

CPC分类号： C12N15/8271 ,  C07K14/415 ,  C12N15/8216 ,  C12N15/8279 ,  C12N15/8282

摘要： The present invention pertains to nucleic acid molecules isolated from Arabidopisis thaliana comprising nucleotide sequences that encode proteins for biotic and abiotic stress tolerance. The invention particularly relates to methods of using nucleic acid molecules and/or proteins from Arabidopisis in transgenic plants to confer enhanced biotic and/or abiotic stress tolerance, and to use such nucleic acids to assist germplasm enhancement by breeding. In particular, the invention pertains to nucleic acid molecules isolated from Arabidopisis thaliana of the BOS1 cDNA and genomic gene and encoding the BOS1 polypeptide. The present invention also pertains to nucleic acid molecules isolated from Arabidopisis thaliana that encode a promoter from the BOS1 gene, and methods of using the promoter. Also, the invention relates to host cells, plants or progeny thereof comprising the nucleic acid molecules or recombinant molecules described herein.

摘要翻译： 本发明涉及从拟南芥中分离的核酸分子，其包含编码用于生物和非生物胁迫耐受性的蛋白质的核苷酸序列。 本发明特别涉及在转基因植物中使用来自Arabidopisis的核酸分子和/或蛋白质赋予增强的生物和/或非生物胁迫耐受性的方法，并且使用这样的核酸通过育种来辅助种质增殖。 特别地，本发明涉及从BOS1 cDNA和基因组基因的拟南芥中分离的编码BOS1多肽的核酸分子。 本发明还涉及从编码来自BOS1基因的启动子的拟南芥中分离的核酸分子以及使用该启动子的方法。 此外，本发明涉及包含本文所述的核酸分子或重组分子的宿主细胞，植物或其后代。

公开(公告)号：US20050031584A1

公开(公告)日：2005-02-10

申请号：US10410980

申请日：2003-04-09

申请人： Shawn DeFrees ,  David Zopf ,  Robert Bayer ,  Caryn Bowe ,  David Hakes ,  Xi Chen

发明人： Shawn DeFrees ,  David Zopf ,  Robert Bayer ,  Caryn Bowe ,  David Hakes ,  Xi Chen

IPC分类号： A61K38/00 ,  C07K1/00 ,  C07K1/107 ,  C07K1/13 ,  C07K9/00 ,  C07K14/505 ,  A61K38/20 ,  C07K14/54

CPC分类号： C07K1/006 ,  A61K38/00 ,  C07K1/1077 ,  C07K1/13 ,  C07K9/00 ,  C07K14/505

摘要： The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.

摘要翻译： 本发明包括用于重组肽分子的方法和组合物，包括向肽添加或缺失一个或多个糖基，和/或向肽中加入修饰基团。

公开(公告)号：US20050024225A1

公开(公告)日：2005-02-03

申请号：US10929784

申请日：2004-08-31

申请人： Michael Sokol ,  Xi Chen

发明人： Michael Sokol ,  Xi Chen

IPC分类号： G05B23/02 ,  G06F15/173

CPC分类号： G05B19/042 ,  G05B2219/23154

摘要： A programmable LED display system is disclosed. The system includes a programmable controller; a driver operative to generate a control signal in response to a signal provided by the programmable controller; and a display device operative to provide a visual representation of the state of the system in response to the control signal. The system also includes means for determining which state condition is displayed when more than one state condition exists.

摘要翻译： 公开了一种可编程LED显示系统。 该系统包括一个可编程控制器; 驱动器，用于响应于由可编程控制器提供的信号而产生控制信号; 以及显示装置，其可操作以响应于所述控制信号提供所述系统的状态的视觉表示。 该系统还包括用于当存在多于一个状态条件时确定显示状态的装置。

公开(公告)号：US6008352A

公开(公告)日：1999-12-28

申请号：US34189

申请日：1998-03-03

申请人： Xi Chen

发明人： Xi Chen

IPC分类号： C07D217/22 ,  C07D405/12 ,  C07D401/04 ,  C07D405/14

CPC分类号： C07D405/12 ,  C07D217/22

摘要： Disclosed are compounds useful in treating psychotic disorders such as schizophrenia and other central nervous system diseases, where the compounds have general Formula I: ##STR1## wherein: Ar represents an aryl or heteroaryl group;R.sub.1 and R.sub.2 independently represent hydrogen, halogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, hydroxy, amino, mono- or di(C.sub.1 -C.sub.6)alkyl amino, cyano or trifluoromethyl; andR.sub.5 represents hydrogen or C.sub.1 -C.sub.6 alkyl.

摘要翻译： 公开了可用于治疗精神病如精神分裂症和其他中枢神经系统疾病的化合物，其中化合物具有通式I：其中：Ar表示芳基或杂芳基; R 1和R 2独立地表示氢，卤素，C 1 -C 6烷基，C 1 -C 4烷氧基，C 1 -C 4烷硫基，羟基，氨基，单或二（C 1 -C 6）烷基氨基，氰基或三氟甲基; 并且R 5表示氢或C 1 -C 6烷基。

公开(公告)号：US5883257A

公开(公告)日：1999-03-16

申请号：US994588

申请日：1997-12-19

申请人： Jun Yuan ,  Xi Chen

发明人： Jun Yuan ,  Xi Chen

IPC分类号： C07D295/12 ,  A61K31/44 ,  A61K31/445 ,  A61K31/451 ,  A61K31/495 ,  A61P25/00 ,  A61P25/18 ,  A61P25/20 ,  A61P25/28 ,  A61P25/30 ,  C07D211/14 ,  C07D211/28 ,  C07D211/70 ,  C07D217/02 ,  C07D295/13 ,  C07D401/12

CPC分类号： C07D295/13 ,  C07D211/14 ,  C07D211/70 ,  C07C2103/24

摘要： Disclosed are compounds of the formula: ##STR1## or the pharmaceutically acceptable acid addition salts thereof, wherein: R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8 and R.sub.9 are the same or different and represent hydrogen, C.sub.1 -C.sub.6 alkyl, halogen, hydroxy, amino, cyano, nitro, trifluoromethyl, trifluoromethoxy, C.sub.1 -C.sub.6 alkoxy, --O.sub.2 CR', --NHCOR', --COR', --SO.sub.m R', where R' is C.sub.1 -C.sub.6 alkyl and wherein m is 0, 1 or 2; orR.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8 and R.sub.9 independently represent --CONR'R", or --NR'R" where R' and R" independently represent hydrogen or C.sub.1 -C.sub.6 alkyl;R.sub.10 is hydrogen or C.sub.1 -C.sub.6 alkyl; andR represents an aminoalkyl group;which compounds are useful in the treatment of affective disorders such as schizophrenia, depression, Alzheimer's disease, movement disorders such as Parkinsonism and dystonia, and other disorders which respond to dopaminergic blockade such as substance abuse and obsessive compulsive disorders. Further, compounds of this invention may be useful in treating the extrapyramidal side effects associated with the use of conventional neuroleptic agents.

摘要翻译： 公开了下式的化合物或其药学上可接受的酸加成盐，其中：R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8和R 9相同或不同，表示氢，C 1 -C 6 烷基，卤素，羟基，氨基，氰基，硝基，三氟甲基，三氟甲氧基，C 1 -C 6烷氧基，-O 2 CR'，-NHCOR'，-COR'，-SO m R'，其中R'是C 1 -C 6烷基， ，1或2; 或R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8和R 9独立地表示-CONR'R“或-NR'R”，其中R'和R“独立地表示氢或C1-C6烷基; R 10是氢或C 1 -C 6烷基; R表示氨基烷基; 哪些化合物可用于治疗情感障碍如精神分裂症，抑郁症，阿尔茨海默氏病，运动障碍如帕金森综合征和肌张力障碍，以及其他对多巴胺能阻滞作用的药物滥用和强迫症。 此外，本发明的化合物可用于治疗与使用常规精神抑制剂相关的锥体束外副作用。

公开(公告)号：US5703235A

公开(公告)日：1997-12-30

申请号：US619351

申请日：1996-03-21

申请人： Jun Yuan ,  Xi Chen

发明人： Jun Yuan ,  Xi Chen

IPC分类号： C07D295/12 ,  A61K31/44 ,  A61K31/445 ,  A61K31/451 ,  A61K31/495 ,  A61P25/00 ,  A61P25/18 ,  A61P25/20 ,  A61P25/28 ,  A61P25/30 ,  C07D211/14 ,  C07D211/28 ,  C07D211/70 ,  C07D217/02 ,  C07D295/13 ,  C07D401/10 ,  C07D295/15

CPC分类号： C07D295/13 ,  C07D211/14 ,  C07D211/70 ,  C07C2103/24

摘要： Disclosed are compounds of the formula: ##STR1## or the pharmaceutically acceptable acid addition salts thereof, wherein: R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8 and R.sub.9 are the same or different and represent hydrogen, C.sub.1 -C.sub.6 alkyl, halogen, hydroxy, amino, cyano, nitro, trifluoromethyl, trifluoromethoxy, C.sub.1 -C.sub.6 alkoxy, --O.sub.2 CR', --NHCOR', --COR', --SO.sub.m R', where R' is C.sub.1 -C.sub.6 alkyl and wherein m is 0, 1 or 2; or R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8 and R.sub.9 independently represent --CONR'R", or --NR'R" where R' and R" independently represent hydrogen or C.sub.1 -C.sub.6 alkyl; R.sub.10 is hydrogen or C.sub.1 -C.sub.6 alkyl; and R represents an aminoalkyl group; which compounds are useful in the treatment of affective disorders such as schizophrenia, depression, Alzheimer's disease, movement disorders such as Parkinsonism and dystonia, and other disorders which respond to dopaminergic blockade such as substance abuse and obsessive compulsive disorders. Further, compounds of this invention may be useful in treating the extrapyramidal side effects associated with the use of conventional neuroleptic agents.

摘要翻译： 公开了下式的化合物或其药学上可接受的酸加成盐，其中：R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8和R 9相同或不同，表示氢，C 1 -C 6 烷基，卤素，羟基，氨基，氰基，硝基，三氟甲基，三氟甲氧基，C 1 -C 6烷氧基，-O 2 CR'，-NHCOR'，-COR'，-SO m R'，其中R'是C 1 -C 6烷基， ，1或2; 或R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8和R 9独立地表示-CONR'R“或-NR'R”，其中R'和R“独立地表示氢或C1-C6烷基; R 10是氢或C 1 -C 6烷基; R表示氨基烷基; 哪些化合物可用于治疗情感障碍如精神分裂症，抑郁症，阿尔茨海默氏病，运动障碍如帕金森综合征和肌张力障碍，以及其他对多巴胺能阻滞作用的药物滥用和强迫症。 此外，本发明的化合物可用于治疗与使用常规精神抑制剂相关的锥体束外副作用。

公开(公告)号：US09980569B1

公开(公告)日：2018-05-29

申请号：US15406447

申请日：2017-01-13

申请人： Xi Chen

发明人： Xi Chen

IPC分类号： A47C1/12 ,  A47C7/00 ,  A47C5/00

CPC分类号： A47C7/002 ,  A47C3/12

摘要： An axial and compressive load support assembly for supporting an axial load and longitudinal compression provides axial load and compressive support for a seat and a load. The assembly provides support through a vertical polyhedron member with radially extending L-shaped legs that from an obtuse angle. The polyhedron member bears an axial load, such as the seat and a load. A plurality of struts extend between the legs and the polyhedron member at an angle. The struts resist longitudinal compression by providing outwards-facing support in a lengthwise direction. A crossbar extends between the strut and the legs. The crossbar is defined by apertures configured to align with the fastening holes in the polyhedron member and enable passage of at least one fastener for detachably fastening the connected legs, struts, and crossbars to the polyhedron member. A wooden extension can be integrated into the second rod of the legs.

公开(公告)号：US20160285581A1

公开(公告)日：2016-09-29

申请号：US15033520

申请日：2014-10-31

申请人： Alan MICKELSON ,  Zheng LI ,  Moustafa MOHAMED ,  Xi CHEN ,  THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE

发明人： Alan Mickelson ,  Zheng Li ,  Moustafa Mohamed ,  Xi Chen

IPC分类号： H04J14/02 ,  H04B10/516 ,  H04B10/80 ,  H04B10/40 ,  H04B10/67

CPC分类号： H04J14/0254 ,  H04B10/40 ,  H04B10/516 ,  H04B10/671 ,  H04B10/801

摘要： A variation-tolerant receiver includes a plurality of receiver resonators configured to demultiplex a multiplexed modulated signal received from at least one wavelength division multiplexing (WDM) transmitter having a plurality of transmitter resonators and wherein operationally each of the receiver resonators has a receiver resonance linewidth not exceeding a minimum spacing between two adjacent transmitter resonances of the transmitter resonators, the receiver resonances collectively spanning a free spectral range of one of the receiver resonators such that the variation-tolerant receiver achieves gapless spectral response. A method passively compensates transmitter-receiver channel mismatch in a transceiver by: separating a broadband carrier into a plurality of narrowband transmitter carriers; modulating the narrowband transmitter carriers to form a plurality of modulated signals; multiplexing each of the modulated signals to form a multiplexed modulated signal; and demultiplexing the multiplexed modulated signal onto a plurality of receiver channels.

摘要翻译： 一种变形容限接收机包括多个接收机谐振器，其被配置为对从具有多个发射机谐振器的至少一个波分多路复用（WDM）发射机接收的复用调制信号进行解复用，并且其中每个接收机谐振器的接收机共振线宽不是 超过发射机谐振器的两个相邻发射机谐振之间的最小间距，接收机谐振共同跨越一个接收机谐振器的自由频谱范围，使得变化容限接收机实现无缝隙频谱响应。 一种方法通过以下方式被动地补偿收发信机中的发射机 - 接收机信道不匹配：将宽带载波分离成多个窄带发射机载波; 调制窄带发射机载波以形成多个调制信号; 复用每个调制信号以形成多路调制信号; 以及将多路复用的调制信号解复用到多个接收机信道上。

公开(公告)号：US09378290B2

公开(公告)日：2016-06-28

申请号：US13331023

申请日：2011-12-20

申请人： Matthew Robert Scott ,  Huihua Hou ,  Weipeng Liu ,  Hao Wei ,  Chiwei Che ,  Byron Huntley Changuion ,  Weijiang Xu ,  Xi Chen

发明人： Matthew Robert Scott ,  Huihua Hou ,  Weipeng Liu ,  Hao Wei ,  Chiwei Che ,  Byron Huntley Changuion ,  Weijiang Xu ,  Xi Chen

IPC分类号： G06F17/30 ,  G06F17/24 ,  G06F17/27

CPC分类号： G06F17/30867 ,  G06F17/24 ,  G06F17/276 ,  G06F17/3087

摘要： An input method editor (IME) described herein couples scenarios of the input of the user with specific network services to offer more relevant and richer candidates for higher input productivity. Data relating to a computer application in which the input candidates are to be input and/or context relating to a user-submitted query is collected and analyzed to determine a scenario. The input candidates may include text candidates and rich candidates. The IME may select a scenario-tuned and type specific engine to identify the text candidates and/or rich candidates. The scenario-tuned text candidate engines leverage scenario-tuned language models and lexicons, and the scenario-tuned rich candidate engines leverage scenario-relevant web services, such as image, mapping, and video search, when available and appropriate.

摘要翻译： 这里描述的输入法编辑器（IME）将具有特定网络服务的用户输入的情景耦合到一起，以提供更多的相关和更丰富的候选，以获得更高的输入生产率。 收集和分析与要输入候选输入的计算机应用有关的数据和/或与用户提交的查询相关的上下文以确定场景。 输入候选人可以包括文本候选人和富有的候选人。 IME可以选择一种情景调节和类型特定的引擎来识别文本候选人和/或富有的候选人。 情景调优的文本候选引擎利用情景调节的语言模型和词典，并且在可用和适当时，情景调优的候选引擎利用与场景相关的Web服务（如图像，映射和视频搜索）。

公开(公告)号：US09353413B2

公开(公告)日：2016-05-31

申请号：US14372143

申请日：2012-01-13

申请人： Chenyu Zhang ,  Xi Chen

发明人： Chenyu Zhang ,  Xi Chen

IPC分类号： C12Q1/68 ,  C12N15/11

CPC分类号： C12Q1/6876 ,  C12N15/111 ,  C12N2310/141 ,  C12N2320/10 ,  C12Q1/6874 ,  C12Q2600/158 ,  C12Q2600/166 ,  C12Q2600/178

摘要： Disclosed are standardized reference genes for microRNAs and the use thereof. The reference gene is microRNA let-7d, let-7g, let-7i or a combination thereof. The reference genes have extremely high stability and accuracy compared to the currently most commonly used reference genes in microRNA quantitation.

摘要翻译： 公开了用于微小RNA的标准参考基因及其用途。 参考基因是microRNA let-7d，let-7g，let-7i或其组合。 参考基因与目前最常用的参考基因在microRNA定量相比具有非常高的稳定性和准确性。