公开(公告)号：US20130010646A1

公开(公告)日：2013-01-10

申请号：US13636709

申请日：2010-06-04

申请人： Yang Liu ,  Nan Li ,  Yuqin Chen ,  Feng Xie ,  Lin Chen ,  Ling Xu ,  Huiying Fang

发明人： Yang Liu ,  Nan Li ,  Yuqin Chen ,  Feng Xie ,  Lin Chen ,  Ling Xu ,  Huiying Fang

IPC分类号： H04W84/18

CPC分类号： H04L41/042 ,  H04L41/12 ,  H04L45/42 ,  H04L67/125 ,  H04W4/70 ,  H04W36/0083 ,  H04W40/248 ,  H04W84/18

摘要： The disclosure discloses a method for managing network topology structure of a Machine to Machine (M2M) network. The method mainly includes: a control station of the M2M network obtains wireless link information of the M2M network; the control station completes establishment and/or adjustment of the network topology structure of the M2M network according to the obtained wireless link information. The disclosure also provides a device for managing network topology structure of an M2M network. By the disclosure, performing self-adaptive management on numerous terminals can be realized by the M2M network; by applying the disclosure to the wireless network management of the M2M network, manpower cost is saved and working efficiency is improved, and also it is of important significance to the smooth development of the telecom operation.

摘要翻译： 本公开公开了一种用于管理机器对机器（M2M）网络的网络拓扑结构的方法。 该方法主要包括：M2M网络的控制站获取M2M网络的无线链路信息; 根据获得的无线链路信息，控制站完成对M2M网络的网络拓扑结构的建立和/或调整。 本公开还提供了一种用于管理M2M网络的网络拓扑结构的设备。 通过本公开，可以通过M2M网络实现对多个终端执行自适应管理; 通过将该公开内容应用于M2M网络的无线网络管理，节省了人力成本，提高了工作效率，对电信运营的顺利发展具有重要意义。

公开(公告)号：US20120276924A1

公开(公告)日：2012-11-01

申请号：US13519896

申请日：2010-07-19

申请人： Jinmin Li ,  Ling Xu ,  Yu Shi ,  Hui Yue

发明人： Jinmin Li ,  Ling Xu ,  Yu Shi ,  Hui Yue

IPC分类号： H04W4/02

CPC分类号： H04W8/245 ,  G06F21/88 ,  H04L67/26 ,  H04W4/029 ,  H04W4/14 ,  H04W12/00503 ,  H04W12/1206

摘要： The disclosure discloses a method for positioning a mobile terminal, which comprises: a server sends a push notification to a mobile terminal; the mobile terminal performs self-positioning after receiving the push notification, to acquire geographical position information regarding the mobile terminal, and sends the geographical position information to the server; the server receives and displays the geographical position information sent by the mobile terminal. The disclosure also discloses a system for positioning a mobile terminal for implementing the method for positioning a mobile terminal and a mobile terminal. With such method and device, the server can be used to send a push notification to the mobile terminal after a user finds that the mobile terminal is lost. The mobile terminal positions geographical position information thereof and sends the geographical position information to the server to help the user retrieve the mobile terminal.

摘要翻译： 本公开公开了一种用于定位移动终端的方法，其包括：服务器向移动终端发送推送通知; 移动终端在接收到推送通知之后执行自定位，以获取关于移动终端的地理位置信息，并将地理位置信息发送到服务器; 服务器接收并显示移动终端发送的地理位置信息。 本公开还公开了一种用于定位用于实现用于定位移动终端和移动终端的方法的移动终端的系统。 利用这种方法和装置，在用户发现移动终端丢失之后，服务器可以用于向移动终端发送推送通知。 移动终端定位其地理位置信息，并将地理位置信息发送到服务器以帮助用户检索移动终端。

公开(公告)号：US20120250563A1

公开(公告)日：2012-10-04

申请号：US13515391

申请日：2010-01-12

申请人： Yang Liu ,  Yuqin Chen ,  Hongyun Qu ,  Ling Xu ,  Zhengguang Zhao ,  Yan Long ,  Xuming Fang ,  Xiaopeng Hu ,  Yue Zhao

发明人： Yang Liu ,  Yuqin Chen ,  Hongyun Qu ,  Ling Xu ,  Zhengguang Zhao ,  Yan Long ,  Xuming Fang ,  Xiaopeng Hu ,  Yue Zhao

IPC分类号： H04L12/26

CPC分类号： H04W40/12 ,  H04L45/42

摘要： The present invention discloses a method and an apparatus for establishing a service route, wherein the method comprises the steps of: collecting, by a control station, channel quality information of all links on each path of a terminal; according to the channel quality information, selecting an access station which establishes a route with the terminal. The present invention realizes selecting the access station which establishes a route with the terminal according to the actual application situation.

摘要翻译： 本发明公开了一种建立业务路由的方法和装置，其特征在于，该方法包括以下步骤：通过控制站收集终端各路径上所有链路的信道质量信息; 根据信道质量信息，选择与终端建立路由的接入站。 本发明实现根据实际应用情况选择与终端建立路由的接入站。

公开(公告)号：US20120034676A1

公开(公告)日：2012-02-09

申请号：US13209124

申请日：2011-08-12

申请人： Paul L. HALLENBECK ,  Seshidar Reddy Police ,  Laura M. Hales ,  Carl M. Hay ,  Shanthi Ganesh ,  Ling Xu ,  Jingping Yang ,  Cheng Cheng

发明人： Paul L. HALLENBECK ,  Seshidar Reddy Police ,  Laura M. Hales ,  Carl M. Hay ,  Shanthi Ganesh ,  Ling Xu ,  Jingping Yang ,  Cheng Cheng

IPC分类号： C12N7/00 ,  C12N5/09

CPC分类号： A61K35/768 ,  A61K39/00 ,  A61K2039/525 ,  C07K14/005 ,  C07K16/1009 ,  C12N7/00 ,  C12N2770/32021 ,  C12N2770/32022 ,  C12N2770/32032 ,  C12N2770/32033 ,  C12N2770/32061 ,  G01N33/5011 ,  G01N2333/085

摘要： The present invention relates to a novel RNA picornavirus that is called Seneca Valley virus (“SVV”). The invention provides isolated SVV nucleic acids and proteins encoded by these nucleic acids. Further, the invention provides antibodies that are raised against the SVV proteins. Because SVV has the ability to selectively kill some types of tumors, the invention provides methods of using SVV and SVV polypeptides to treat cancer. Because SVV specifically targets certain tumors, the invention provides methods of using SVV nucleic acids and proteins to detect cancer. Additionally, due to the information provided by the tumor-specific mechanisms of SVV, the invention provides methods of making new oncolytic virus derivatives and of altering viruses to have tumor-specific tropisms.

摘要翻译： 本发明涉及一种称为塞尼卡谷病毒（“SVV”）的新型小RNA病毒RNA。 本发明提供了由这些核酸编码的分离的SVV核酸和蛋白质。 此外，本发明提供针对SVV蛋白产生的抗体。 由于SVV具有选择性地杀死一些类型的肿瘤的能力，本发明提供了使用SVV和SVV多肽治疗癌症的方法。 由于SVV特异性靶向某些肿瘤，本发明提供了使用SVV核酸和蛋白质来检测癌症的方法。 另外，由于SVV的肿瘤特异性机制提供的信息，本发明提供了制备新的溶瘤病毒衍生物和改变病毒以具有肿瘤特异性嗜性的方法。

公开(公告)号：US20120034255A1

公开(公告)日：2012-02-09

申请号：US13232775

申请日：2011-09-14

申请人： Peter Kwong ,  John Mascola ,  Gary Nabel ,  Richard Wyatt ,  Barna Dey ,  Ling Xu ,  Tongqing Zhou ,  Joseph Sodroski ,  Wen Yuan ,  Shi-Hua Xiang

发明人： Peter Kwong ,  John Mascola ,  Gary Nabel ,  Richard Wyatt ,  Barna Dey ,  Ling Xu ,  Tongqing Zhou ,  Joseph Sodroski ,  Wen Yuan ,  Shi-Hua Xiang

IPC分类号： A61K39/21 ,  A61P31/18 ,  C07K14/16

CPC分类号： C07K14/005 ,  A61K39/12 ,  A61K39/21 ,  A61K2039/53 ,  A61K2039/54 ,  A61K2039/545 ,  C07K14/70514 ,  C12N2740/15022 ,  C12N2740/16122 ,  C12N2740/16134

摘要： Stabilized forms of gp120 polypeptide, nucleic acids encoding these stabilized forms, vectors comprising these nucleic acids, and methods of using these polypeptides, nucleic acids, vectors and host cells are disclosed. Crystal structures and computer systems including atomic coordinates for stabilized forms of gp120, and gp120 with an extended V3 loop, and methods of using these structures and computer systems are also disclosed.

公开(公告)号：US08078199B2

公开(公告)日：2011-12-13

申请号：US12278020

申请日：2007-02-15

申请人： Ning Wang ,  Ling Xu ,  Hong Chen ,  Dushi Lou

发明人： Ning Wang ,  Ling Xu ,  Hong Chen ,  Dushi Lou

IPC分类号： H04W68/00 ,  H04B7/00

CPC分类号： H04W68/02 ,  H04W76/10 ,  H04W80/04

摘要： An implementation method and system for accelerating the paging access of a mobile station in broadband wireless system are disclosed, and this system comprises base stations, mobile stations, an anchor access network gateway, an authenticator and a paging controller. The implementation method includes: (a) the anchor access network gateway sends to the base station a Paging Announce message including at least mobile station identifier and the authenticator identifier of the mobile station; (b) the base station keeps the corresponding relationship of the authenticator identifier and the mobile station, and sends a MOS-PAG-ADV message to the mobile station; (c) after the base station receives the RNG-REQ message from the mobile station, it interacts with the authenticator using the authenticator identifier to obtain the authentication key and perform the authentication; and acquire the information of mobile station from the paging controller; (d) before or after the base station requests the anchor access network gateway to establish a data channel, it sends a RNG-RES message to the mobile station; (e) after the anchor access network gateway receives the Data Channel Establishment Acknowledgement message, it informs the paging controller to delete the mobile station information thereon. The present invention can accelerate the process of paging access of the mobile station.

摘要翻译： 公开了一种用于加速宽带无线系统中的移动台的寻呼接入的实现方法和系统，该系统包括基站，移动台，锚接入网关，认证器和寻呼控制器。 所述实现方法包括：（a）所述锚定接入网络网关向所述基站发送包括移动台标识符和所述移动台的认证符标识符的寻呼宣告消息; （b）基站保持认证者标识符与移动台的对应关系，向移动台发送MOS-PAG-ADV消息; （c）在基站从移动站接收到RNG-REQ消息之后，使用认证者标识符与认证者进行交互，获得认证密钥并进行认证; 并从寻呼控制器获取移动台的信息; （d）在基站请求主机接入网关建立数据信道之前或之后，向移动台发送RNG-RES消息; （e）锚定接入网关收到数据信道建立确认消息后，通知寻呼控制器删除其上的移动台信息。 本发明可以加速移动台的寻呼接入过程。

公开(公告)号：US20090280840A1

公开(公告)日：2009-11-12

申请号：US12301531

申请日：2007-03-12

申请人： Ling Xu ,  Qinghai Zeng

发明人： Ling Xu ,  Qinghai Zeng

IPC分类号： H04W68/00

CPC分类号： H04W68/00

摘要： A method for improving performance of mobile broadband wireless access system is disclosed. The method comprises the steps: first, a paging controller controls base stations to transmit paging broadcasting messages to mobile stations; the mobile stations respond to the paging controller through the base station which responds with the mobile stations; then, the paging controller transmits paging notice message to note that the base stations which do not respond with the mobile stations stop transmitting the paging broadcasting messages in the paging group; last, the base stations in the paging group immediately stop transmitting the paging broadcasting messages as to the mobile station, and delete the corresponding data, after they receive the paging notice message which the paging controller transmits. By use of the present method, the base station processing and the storing cost are not remarkably increased, legal-user's paging errors caused by non-legal accessing message are avoided, and the occupying of network wireless resources and system resources can be effectively reduced.

摘要翻译： 公开了一种提高移动宽带无线接入系统性能的方法。 该方法包括以下步骤：首先，寻呼控制器控制基站向移动台发送寻呼广播消息; 移动台通过基站对呼叫控制器进行响应，响应移动台; 然后，寻呼控制器发送寻呼通知消息，注意到与移动站不进行响应的基站停止在寻呼组中发送寻呼广播消息; 最后，寻呼组中的基站立即停止向移动台发送寻呼广播消息，并且在接收到寻呼控制器发送的寻呼通知消息之后删除对应的数据。 通过使用本方法，基站处理和存储成本不会显着增加，避免了由非合法访问消息引起的合法用户的寻呼错误，可以有效降低网络无线资源和系统资源的占用。

公开(公告)号：US20090214588A1

公开(公告)日：2009-08-27

申请号：US11632522

申请日：2005-07-15

申请人： Gary J. Nabel ,  Yue Huang ,  Zengguang Wang ,  Ling Xu ,  Bimal Chakrabarti ,  Lan Wu ,  Zhi-yong Yang ,  Jason G.D. Gall ,  C. Richter King

发明人： Gary J. Nabel ,  Yue Huang ,  Zengguang Wang ,  Ling Xu ,  Bimal Chakrabarti ,  Lan Wu ,  Zhi-yong Yang ,  Jason G.D. Gall ,  C. Richter King

IPC分类号： A61K39/21 ,  C12N15/11 ,  C07K14/00

CPC分类号： A61K39/21 ,  A61K39/00 ,  A61K39/12 ,  A61K2039/53 ,  A61K2039/54 ,  A61K2039/545 ,  A61K2039/57 ,  A61K2039/70 ,  C07K14/005 ,  C12N2740/16122 ,  C12N2740/16134 ,  C12N2740/16171 ,  C12N2740/16222 ,  C12N2740/16234 ,  C12N2740/16271 ,  C12N2740/16322 ,  C12N2740/16334 ,  C12N2740/16371

摘要： The present disclosure provides compositions for eliciting an immune response, including a prophylactic immune response, against human immunodeficiency virus. The composition includes nucleic acid constructs encoding HIV antigenic polypeptides of multiple clades or strains. Methods for eliciting an immune response by administering the composition to a subject are also provided.

摘要翻译： 本公开提供了针对人类免疫缺陷病毒引发免疫应答（包括预防性免疫应答）的组合物。 该组合物包括编码多个进化枝或菌株的HIV抗原多肽的核酸构建体。 还提供了通过将受试者施用组合物引起免疫应答的方法。

公开(公告)号：US08699451B2

公开(公告)日：2014-04-15

申请号：US12595622

申请日：2007-12-12

申请人： Sean Cai ,  Ling Xu

发明人： Sean Cai ,  Ling Xu

IPC分类号： H04W4/00

CPC分类号： H04B7/155 ,  H04B7/2606 ,  H04W16/26

摘要： A method for updating a connection relationship of a wireless relay station, comprises the following steps of: (a) a wireless relay station RS1 already connecting to a wireless communication network group comprising a base station and wireless relay stations subjected to the base station, and if determining that the connection relationship of RS1 needs to be changed, selecting a target node; (b) instructing RS1 to update the connection to the target node, and after receiving the instructions, RS1 starting a connection update, establishing a wireless link to a new node and releasing no longer used resource in an existing data tunnel. The present invention can fulfill the update of the connection relationship of a wireless relay station, and can take steps to further guarantee the service suspension time of the terminals and RSs subjected to the wireless relay station is the shortest.

摘要翻译： 一种用于更新无线中继站的连接关系的方法，包括以下步骤：（a）已经连接到包括基站的无线通信网络组的无线中继站RS1和经受基站的无线中继站，以及 如果确定需要改变RS1的连接关系，则选择目标节点; （b）指示RS1更新与目标节点的连接，在接收到指令后，RS1开始连接更新，建立到新节点的无线链路，并释放现有数据隧道中不再使用的资源。 本发明可以实现无线中继站的连接关系的更新，并且可以采取步骤进一步保证终端的服务暂停时间和经受无线中继站的RS最短。

公开(公告)号：US20130090475A1

公开(公告)日：2013-04-11

申请号：US13704379

申请日：2010-12-02

申请人： Mingfeng Shi ,  Dan Li ,  Ling Xu

发明人： Mingfeng Shi ,  Dan Li ,  Ling Xu

IPC分类号： C07D295/15

CPC分类号： C07D295/15 ,  A61K31/495

摘要： A process for the preparation of ranolazine comprises the step of condensing N-(2,6-dimethylphenyl)-1-piperazinyl acetamide with a compound of formula (I) to obtain ranolazine, in which X is chlorine or bromine Ranolazine is prepared by condensing ring-opening halide which replaces epoxide in this process.

摘要翻译： 制备雷诺嗪的方法包括将N-（2,6-二甲基苯基）-1-哌嗪基乙酰胺与式（I）化合物缩合以获得雷诺嗪的步骤，其中X是氯或溴。 在此过程中取代环氧化物的开环卤化物。