摘要:
The present disclosure provides compositions for eliciting an immune response, including a prophylactic immune response, against human immunodeficiency virus. The composition includes nucleic acid constructs encoding HIV antigenic polypeptides of multiple clades or strains. Methods for eliciting an immune response by administering the composition to a subject are also provided.
摘要:
The present disclosure provides compositions for eliciting an immune response, including a prophylactic immune response, against human immunodeficiency virus. The composition includes nucleic acid constructs encoding HIV antigenic polypeptides of multiple clades or strains. Methods for eliciting an immune response by administering the composition to a subject are also provided.
摘要:
The present disclosure provides compositions for eliciting an immune response, including a prophylactic immune response, against human immunodeficiency virus. The composition includes nucleic acid constructs encoding HIV antigenic polypeptides of multiple clades or strains. Methods for eliciting an immune response by administering the composition to a subject are also provided.
摘要:
A method for treating highly concentrated resin-desorption liquid generated from wastewater deep purification, including channeling the highly concentrated desorption liquid generated from anion exchange resin treatment through a nanofiltration membrane, the liquid being separated into nanofiltration permeate that can be reused as the desorption agent and highly concentrated nanofiltration retentate; adding a coagulating agent to the highly concentrated nanofiltration retentate to generate coagulation-precipitation; subjecting the supernatant formed after the coagulation-precipitation process to Fenton oxidation or ozone oxidation; after the reaction, adding to the liquid an alkali solution for further coagulation-precipitation; then channeling the liquid so treated back to the biochemical system of biochemical effluent treatment for further biodegradation is provided. The recycled treatment of the highly concentrated desorption liquid consequently reduces the treatment cost and prevents secondary pollution by realizing innocuous treatment and reclamation of resin-desorption liquid as well as reduction of its total volume.
摘要:
The disclosure provides an anchor authenticator relocation method and system. The method includes: after an old authenticator accepts an anchor authenticator relocation request of a Mobile Station (MS), a new authenticator sends an authenticator relocation request to an AAA server; when the AAA server's verification on the new authenticator is passed and the old authenticator confirms that the new authenticator is trusted, the anchor authenticator is relocated to the new authenticator. The disclosure provides a detailed solution to perform anchor authenticator relocation without re-authentication.
摘要:
The present invention relates to a novel RNA picornavirus that is called Seneca Valley virus (“SVV”). The invention provides isolated SVV nucleic acids and proteins encoded by these nucleic acids. Further, the invention provides antibodies that are raised against the SVV proteins. Because SVV has the ability to selectively kill some types of tumors, the invention provides methods of using SVV and SVV polypeptides to treat cancer. Because SVV specifically targets certain tumors, the invention provides methods of using SVV nucleic acids and proteins to detect cancer. Additionally, due to the information provided by the tumor-specific mechanisms of SVV, the invention provides methods of making new oncolytic virus derivatives and of altering viruses to have tumor-specific tropisms.
摘要:
Stabilized forms of gp120 polypeptide, nucleic acids encoding these stabilized forms, vectors comprising these nucleic acids, and methods of using these polypeptides, nucleic acids, vectors and host cells are disclosed. Crystal structures and computer systems including atomic coordinates for stabilized forms of gp120, and gp120 with an extended V3 loop, and methods of using these structures and computer systems are also disclosed.
摘要:
A method for a device to join a wireless communication network, after the device accesses to the wireless communication network group through a source node, the method comprising the following steps of: (a) if the device needs a handover, completes the handover successfully by accessing to a target node and establishes a service connection, proceeding to step (b), otherwise proceeding to step (c); (b) a management node of the wireless communication network group to which the target node accessed to by the device belongs updating a stored wireless network topology information of the wireless network group, to complete the joining of said wireless communication device, and the method ending; (c) a management node of the wireless communication network group to which the source node accessed to by the device belongs updating a stored wireless network topology information of the wireless communication network group, to complete the joining of said device.
摘要:
The invention relates to a polyoxometalate topical composition for removing a contaminant from an environment, comprising a topical carrier and at least one polyoxometalate, with the proviso that the polyoxometalate is not H5PV2Mo10O40; K5Si(H2O)MnIIIW11O39; K4Si(H2O)MnIVW11O39; or K5CoIIIW12O40. The invention further relates to a method for removing a contaminant from an environment, comprising contacting the polyoxometalate topical composition of the present invention with the environment containing the contaminant for a sufficient time to remove the contaminant from the environment. The invention further relates to a modified polyoxometalate, wherein the modified polyoxometalate comprises the admixture of (1) a polyoxometalate and (2) a cerium compound, a silver compound, a gold compound, a platinum compound, or a combination thereof. The invention further relates to a method for removing a contaminant from an environment, comprising contacting a modified material with the environment containing the contaminant for a sufficient time to remove the contaminant from the environment, wherein the modified material comprises (1) a material and (2) a metal compound comprising a transition metal compound, an actinide compound, a lanthanide compound, or a combination thereof, wherein the metal compound is not a polyoxometalate. The invention further relates to an article comprising the modified material of the present invention.
摘要:
Isolated immunogens including a HIV-1 gp120 polypeptide or immunogenic fragment thereof stabilized in a CD4 bound confirmation by crosslinked cysteines, and methods of their use are disclosed. The immunogens are useful, for example, for generating an immune response to HIV-1 gp120 in a subject.