公开(公告)号：US20140314875A1

公开(公告)日：2014-10-23

申请号：US14322564

申请日：2014-07-02

申请人： Malaysian Palm Oil Board ,  Commonwealth Scientific and Industrial Research Organisation (CSIRO)

发明人： Mahinda Abeywardena ,  Ravigadevi Sambanthamurthi ,  Yew Ai Tan ,  Kalyana Sundram P. Manickam ,  Mohd Basri Wahid

IPC分类号： A61K36/889 ,  A23L1/30 ,  A61K45/06

CPC分类号： A61K36/889 ,  A23L33/105 ,  A23V2002/00 ,  A61K45/06 ,  A23V2200/326 ,  A23V2250/21

摘要： The present invention relates to a composition for the use in improving vascular health, including treating and preventing vascular diseases and diseases related thereto, using a botanical extract of oil palm vegetation liquor from the palm oil milling process.

摘要翻译： 本发明涉及一种用于改善血管健康的组合物，包括使用来自棕榈油研磨过程的油棕榈植物液的植物提取物来治疗和预防与之相关的血管疾病和疾病。

公开(公告)号：US12058968B2

公开(公告)日：2024-08-13

申请号：US17131384

申请日：2020-12-22

申请人： Malaysian Palm Oil Board

发明人： Rajinder Singh ,  Leslie Low Eng Ti ,  Leslie Ooi Cheng Li ,  Meilina Ong Abdullah ,  Rajanaidu Nookiah ,  Ravigadevi Sambanthamurthi ,  Andrew Van Brunt ,  Muhammad A. Budiman ,  Steven W. Smith ,  Nathan D. Lakey ,  Rob Martienssen ,  Jared Ordway

IPC分类号： A01H1/04 ,  A01H5/08 ,  A01H5/10 ,  C07K14/415 ,  C12N15/82 ,  C12Q1/6895

CPC分类号： A01H1/045 ,  A01H5/08 ,  A01H5/10 ,  C07K14/415 ,  C12N15/8261 ,  C12Q1/6895 ,  C12Q2600/13 ,  C12Q2600/156 ,  Y02A40/146

摘要： Nucleic acid and polypeptide sequences for predicting and controlling shell phenotype in palm.

公开(公告)号：US11033596B2

公开(公告)日：2021-06-15

申请号：US15462433

申请日：2017-03-17

申请人： Malaysian Palm Oil Board

发明人： Ravigadevi Sambanthamurthi ,  Tan Yew AI ,  T. G. Sambandan ,  Cho Kyun Rha ,  Anthony J. Sinskey

IPC分类号： A61K36/889 ,  A61K31/191 ,  A61K31/192 ,  A61K31/235

摘要： Compositions comprising oil palm phenolics and shikimic acid or derivatives thereof and their use in enhancing anti-oxidative and anti-inflammatory properties.

公开(公告)号：US20210105961A1

公开(公告)日：2021-04-15

申请号：US17131384

申请日：2020-12-22

申请人： Malaysian Palm Oil Board

发明人： Rajinder Singh ,  Leslie Low Eng Ti ,  Leslie Ooi Cheng Li ,  Meilina Ong Abdullah ,  Rajanaidu Nookiah ,  Ravigadevi Sambanthamurthi ,  Andrew Van Brunt ,  Muhammad A. Budiman ,  Steven W. Smith ,  Nathan D. Lakey ,  Rob Martienssen ,  Jared Ordway

IPC分类号： A01H1/04 ,  C12Q1/6895 ,  A01H5/08 ,  C07K14/415 ,  C12N15/82 ,  A01H5/10

摘要： Nucleic acid and polypeptide sequences for predicting and controlling shell phenotype in palm.

公开(公告)号：US10603348B2

公开(公告)日：2020-03-31

申请号：US15944616

申请日：2018-04-03

申请人： MALAYSIAN PALM OIL BOARD

发明人： T.G. Sambandan ,  ChoKyun Rha ,  Anthony J. Sinskey ,  Ravigadevi Sambanthamurthi ,  Yew Ai Tan ,  Kalyana Sundram P. Manickam ,  Mohd Basri Wahid

IPC分类号： A61K36/889

摘要： A composition comprising caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, said caffeoylshikimic acids and their derivatives extracted from any part of oil palm including but not confined to the vegetation liquor of palm oil milling and palm oil mill effluent, and a method for use in the preparation of a composition containing caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, said caffeoylshikimic acids and their derivatives. The method includes the steps of pre-concentrating an extract containing the caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, caffeoylshikimic acids and their derivatives and isolating the caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, said caffeoylshikimic acids and their derivatives from said extract by liquid chromatography, wherein the elution activity of said caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, with the caffeoylshikimic acids and their derivatives varying depending on the stationary phase and the composition of the mobile phase.

公开(公告)号：US10308583B2

公开(公告)日：2019-06-04

申请号：US15943777

申请日：2018-04-03

申请人： MALAYSIAN PALM OIL BOARD

发明人： Sambandan Tg ,  Chokyun Rha ,  Ravigadevi Sambanthamurthi ,  Anthony J. Sinskey ,  Yew Ai Tan ,  Kalyana Sundram P. Manickam ,  Mohd Basri Wahid

IPC分类号： A61K31/19 ,  C07C51/50 ,  C07C51/48 ,  C07C51/42 ,  C12N9/10

摘要： The present invention provides compositions and method for production of shikimic acid based on extracts obtained from oil palm-based materials, and more particularly oil palm-based waste materials and by-products. The method includes purifying shikimic acid from extracts comprising oil palm phenolics (OPP).

公开(公告)号：US20180314794A1

公开(公告)日：2018-11-01

申请号：US15962359

申请日：2018-04-25

申请人： Malaysian Palm Oil Board

发明人： Meilina Ong Abdullah ,  Ooi Siew Eng ,  Leslie Low Eng Ti ,  Rajinder Singh ,  Rajanaidu Nookiah ,  Ravigadevi Sambanthamurthi ,  Nan Jiang ,  Steven W. Smith ,  Nathan D. Lakey ,  Rob Martienssen ,  Jared Ordway ,  Michael Hogan

IPC分类号： G06F19/22 ,  C12N15/113 ,  C12Q1/6895 ,  G06F19/18

CPC分类号： G06F19/22 ,  C12N15/113 ,  C12N2310/14 ,  C12Q1/6895 ,  C12Q2537/164 ,  C12Q2600/13 ,  C12Q2600/154 ,  C12Q2600/158 ,  C12Q2600/16 ,  G06F19/18

摘要： Methods, compositions, kits, and computer program code are provided for predicting somaclonal abnormality (e.g., a Mantled phenotype) in a plant and or sorting plants based on the predicted presence or absence of somaclonal abnormality.

公开(公告)号：US20180185433A1

公开(公告)日：2018-07-05

申请号：US15898477

申请日：2018-02-17

申请人： Malaysian Palm Oil Board

发明人： Soon Sen Leow ,  Ravigadevi Sambanthamurthi ,  Yew Ai Tan ,  Kalyana Sundram P. Manickam ,  Mohd Basri wahid

IPC分类号： A61K36/889 ,  A61K31/05

CPC分类号： A61K36/889 ,  A61K31/05

摘要： A composition comprising extracts containing oil palm phenolics in an amount effective for use in a method of reducing cholesterol biosynthesis and thus preventing obesity. The composition up regulates fatty acid beta oxidation and down regulates cholesterol biosynthesis in livers. The composition is useful for prevention of obesity associated diseases. The composition delays the onset of obesity and attenuates the inflammatory response of atherogenic diet, whereby the composition aids to suppress the inflammatory response thereby ameliorating artherosclerosis. The composition delays weight gain or obesity thereby preventing the effects of dyslipidemia.

公开(公告)号：US09931368B2

公开(公告)日：2018-04-03

申请号：US14531731

申请日：2014-11-03

申请人： Malaysian Palm Oil Board

发明人： Soon Sen Leow ,  Ravigadevi Sambanthamurthi ,  Yew Ai Tan ,  Kalyana Sundram P. Manickam ,  Mohd Basri Wahid

IPC分类号： A61K36/889 ,  A61K31/05

CPC分类号： A61K36/889 ,  A61K31/05

摘要： A composition comprising extracts containing oil palm phenolics in an amount effective for use in a method of reducing cholesterol biosynthesis and thus preventing obesity. The composition up regulates fatty acid beta oxidation and down regulates cholesterol biosynthesis in livers. The composition is useful for prevention of obesity associated diseases. The composition delays the onset of obesity and attenuates the inflammatory response of atherogenic diet, whereby the composition aids to suppress the inflammatory response thereby ameliorating artherosclerosis. The composition delays weight gain or obesity thereby preventing the effects of dyslipidemia.

公开(公告)号：US09839662B2

公开(公告)日：2017-12-12

申请号：US14691410

申请日：2015-04-20

申请人： Malaysian Palm Oil Board

发明人： Hjh Che Anishas HJ. Che Idris ,  Nagendran Balasundram ,  Ravigadevi Sambanthamurthi ,  Yew Ai Tan ,  Kalyana Sundram P. Manickam ,  Mohd Basri Wahid

IPC分类号： A61K36/889 ,  A61K31/355 ,  A61K31/192 ,  A61K31/353

CPC分类号： A61K36/889 ,  A61K31/192 ,  A61K31/353 ,  A61K31/355 ,  A61K2300/00

摘要： The invention provides a composition the prevention and treatment of cardiovascular disease, wherein said composition compounds obtained from palm oil mill effluents, in particular from vegetative liquor from the milling of palm oil fruit.