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公开(公告)号：US20220057362A1
公开(公告)日：2022-02-24
申请号：US17407667
申请日：2021-08-20
Applicant: Meso Scale Technologies, LLC
Inventor： Mark Billadeau , Nicholas Carbone , Charles Clinton , Scott Dowdell , Manish Kochar , Nicholas Fox-Lyon , Bandele Jeffrey-Coker , Alexander Tucker-Schwartz , George Sigal , Gisbert Spieles , Jules Vandersarl , Jacob Wohlstadter
IPC: G01N27/49 , G01N27/327
Abstract: An electrochemical cell includes a plurality of working electrode zones disposed, and defining a pattern, on a surface of the cell and at least one auxiliary electrode disposed on the surface. The auxiliary electrode may have a defined interfacial potential.
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公开(公告)号：US11135594B2
公开(公告)日：2021-10-05
申请号：US16292521
申请日：2019-03-05
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , Bandele Jeffrey-Coker , Kenneth Page , Sandor Kovacs , Sudeep Kumar , Kristian Roth
IPC: B01L3/00 , F16K11/074
Abstract: Assay cartridges are described that have a plurality of chambers and a fluidic network that includes fluidic conduits and a multi-port valve designed to selectively connect the valve inlet and one valve outlet through a fluidic connector in the valve as the remaining valve outlets are sealed.
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公开(公告)号：US11065615B2
公开(公告)日：2021-07-20
申请号：US15882914
申请日：2018-01-29
Applicant: MESO SCALE TECHNOLOGIES, LLC
Inventor： Eli N. Glezer , Bandele Jeffrey-Coker , Jeffery D. Debad , Sudeep M. Kumar , George B. Sigal , Gisbert Spieles , Michael Tsionsky , Michael Warnock
IPC: G01N33/543 , B01L3/00 , G01N33/53
Abstract: We describe assay modules (e.g., assay plates, cartridges, multi-well assay plates, reaction vessels, etc.), processes for their preparation, and method of their use for conducting assays. Reagents may be present in free form or supported on solid phases including the surfaces of compartments (e.g., chambers, channels, flow cells, wells, etc.) in the assay modules or the surface of colloids, beads, or other particulate supports. In particular, dry reagents can be incorporated into the compartments of these assay modules and reconstituted prior to their use in accordance with the assay methods. A desiccant material may be used to maintain and stabilize these reagents in a dry state.
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公开(公告)号：US10782227B2
公开(公告)日：2020-09-22
申请号：US16845560
申请日：2020-04-10
Applicant: Meso Scale Technologies, LLC.
Inventor： Jacob N. Wohlstadter , Eli Glezer , James Wilbur , George Sigal , Kent Johnson , Charles Clinton , Alan Kishbaugh , Bandele Jeffrey-Coker , Jeff D. Debad , Alan B. Fischer
Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
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Patent Agency Ranking
公开(公告)号：USD889685S1
公开(公告)日：2020-07-07
申请号：US29675799
申请日：2019-01-04
Applicant: Meso Scale Technologies, LLC.
Designer： Aaron Leimkuehler , Manish Kochar , Jennifer Parker , Nicholas Sammons , Bandele Jeffrey-Coker
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公开(公告)号：US10539501B2
公开(公告)日：2020-01-21
申请号：US15587968
申请日：2017-05-05
Applicant: Meso Scale Technologies, LLC.
Inventor： Jacob N. Wohlstadter , Eli Glezer , James Wilbur , George Sigal , Kent Johnson , Charles Clinton , Alan Kishbaugh , Bandele Jeffrey-Coker , Jeff D. Debad , Alan B. Fischer
Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
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公开(公告)号：US20190219794A1
公开(公告)日：2019-07-18
申请号：US16360257
申请日：2019-03-21
Applicant: Meso Scale Technologies, LLC.
Inventor： Ian Chamberlin , Charlles M. Clinton , Eli N. Glezer , Bandele Jeffrey-Coker , Manish Kochar , Sandor Kovacs , D.T. Le , Aaron Leimkuehler , George Sigal , Leo Tabakin , Jon Willoughby
CPC classification number: G02B7/36 , G01N21/253 , G01N21/6452 , G01N35/028
Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.
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公开(公告)号：US20140378341A1
公开(公告)日：2014-12-25
申请号：US14478197
申请日：2014-09-05
Applicant: Meso Scale Technologies, LLC
Inventor： Eli N. Glezer , Jonathan K. Leland , Mark A. Billadeau , Joseph M. Leginus , Bandele Jeffrey-Coker , Jeff D. Debad , Koustubh A. Phalnikar , Sriram Jambunathan
IPC: G01N33/543 , G01N21/76
CPC classification number: G01N21/76 , B01J19/0046 , B01J2219/00653 , B01J2219/00725 , B01J2219/0074 , B01L3/5027 , B01L3/502715 , B01L3/5029 , B01L9/527 , B01L2200/0684 , B01L2200/10 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0867 , B01L2300/0887 , B01L2400/049 , B01L2400/0688 , B33Y80/00 , C12Q1/001 , C40B40/10 , G01N27/30 , G01N33/5438 , G01N2458/30 , Y10T436/25 , Y10T436/25375 , Y10T436/255
Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.
Abstract translation: 测定模块，优选测定盒，被描述为可用于控制模块操作的方面的读取器设备。 模块优选地包括具有集成电极的检测室，其可用于执行电极诱导的发光测量。 描述了以这种控制方式将测定试剂固定在这些电极和其它表面上的方法。 还描述了具有检测室，优选地具有集成电极的测定模块和盒，以及可以包括样品室，废物室，导管，通风口，气泡阱，试剂室，干试剂丸区等的其它流体组分。 在某些优选实施例中，这些模块适于接收和分析在施用器棒上收集的样品。
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公开(公告)号：US20140151224A1
公开(公告)日：2014-06-05
申请号：US14170721
申请日：2014-02-03
Applicant: Meso Scale Technologies, LLC
Inventor： Eli N. Glezer , Jonathan K. Leland , Mark A. Billadeau , Joseph M. Leginus , Bandele Jeffrey-Coker , Jeff D. Debad , Koustubh A. Phalnikar , Sriram Jambunathan
IPC: G01N27/30
CPC classification number: G01N21/76 , B01J19/0046 , B01J2219/00653 , B01J2219/00725 , B01J2219/0074 , B01L3/5027 , B01L3/502715 , B01L3/5029 , B01L9/527 , B01L2200/0684 , B01L2200/10 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0867 , B01L2300/0887 , B01L2400/049 , B01L2400/0688 , B33Y80/00 , C12Q1/001 , C40B40/10 , G01N27/30 , G01N33/5438 , G01N2458/30 , Y10T436/25 , Y10T436/25375 , Y10T436/255
Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.
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